Inverse Problems
An inverse problem is a collection of trials which define a multi-simulation optimization problem. The solution to an inverse problem are the "good parameters" which make the simulations simultaniously fit their respective data sufficiently well.
Constructing InverseProblems
JuliaSimModelOptimizer.InverseProblem
— TypeInverseProblem(trials, model, search_space)
The InverseProblem
stores the information needed to perform the optimization and find the model
parameters and/or initial conditions that best fit the data. The model
is an MTK ODESystem
describing the dynamics of the investigated system. The trials
constitute a collection that groups the individual trials according to their interpretation, such as IndependentTrials
(there is no link between trials) or SteadyStateTrials
(the first trial computes a steady state that other trials may continue to solve from).
The search_space
is a Vector
of pairs. Each pair consists of a parameter or initial condition to be optimized and its lower and upper bounds. When using an MCMCOpt
method, search_space
can hold distributions for each parameter instead of bounds, e.g. see TransformedBeta
or see the Distributions.jl documentation) for more options.