Name	Description
`minus_k1`	`172.1`
`eq_NaPi`	`224.0`
`body_temp`	`310.0`
`eq_HPi`	`0.000169`
`eq_K_e`	`0.213`
`partition_factor`	`-0.031288692380984445`
`cPi_sum`	`4.2`
`minus_k2`	`40.1`
`cH`	`8.1283e-5`
`k4`	`320.0`
`eq_Na_base_i`	`2.49`
`eq_KPi`	`292.0`
`eq_MgATP`	`2.51`
`cK_e`	`5.4`
`eq_K_i`	`0.5`
`cMgATP`	`9.8`
`k1`	`1050.0`
`gas_const`	`8.314`
`cK_i`	`140.0`
`k3`	`2000.0`
`minus_k4`	`40.1`
`minus_k3`	`79287.1`
`cNa_e`	`150.0`
`faraday_const`	`96485.0`
`eq_Na_base_e`	`15.5`
`k2`	`481.0`

States:

Name	Description
`Vm(time)`	`-150.0`
`cMgADP(time)`	`0.01`
`cNa_i(time)`	`50.0`

sneyd_dufour_2002 — v0.0.1

Sneyd, Dufour, 2002

Details

Parameters:

Name	Description
`k_2a`	`37.4`
`k_4a`	`4.0`
`k_3a`	`0.11`
`k_3b`	`29.8`
`c`	`1.0`
`L_3`	`0.025`
`l_4a`	`1.7`
`l_4b`	`2.5`
`L_1`	`0.12`
`l_2b`	`0.8`
`k_1a`	`0.64`
`k_4b`	`0.54`
`k_1b`	`0.04`
`k_2b`	`1.4`
`l_6a`	`4707.0`
`l_6b`	`11.4`
`l_2a`	`1.7`
`p`	`10.0`
`L_5`	`54.7`

States:

Name	Description
`O(time)`	`0.0`
`I_2(time)`	`0.0`
`A(time)`	`0.0`
`R(time)`	`1.0`
`I_1(time)`	`0.0`

sneyd_tsaneva-atanasova_yule_thompson_shuttleworth_2004: sneyd_tsaneva_atanasova_yule_thompson_shuttleworth_2004 — v0.0.1

Sneyd, Tsaneva-Atanasova, Yule, Thompson, Shuttleworth, 2004

Details

sneyd_tsanevaatanasova_bruce_straub_giovannucci_yule_2003 — v0.0.1

Sneyd, Tsanevaatanasova, Bruce, Straub, Giovannucci, Yule, 2003

Details

sneyd_wetton_charles_sanderson_1995 — v0.0.1

Snyed, Wetton, Charles, Sanderson, 1995

Details

Intercellular calcium waves mediated by diffusion of inostol trisphosphate: a two dimensional model.

Parameters:

Name	Description
`tau_h`	`0.2`
`b`	`0.11`
`k_flux`	`3.0`
`beta`	`0.15`
`IPR_3_flux`	`0.72`
`k_mu`	`0.01`
`k_2`	`0.7`
`V_p`	`0.08`
`gamma`	`1.0`
`k_gamma`	`0.27`
`k_p`	`1.0`
`k_1`	`0.7`

States:

Name	Description
`P(time)`	`0.0`
`h(time)`	`1.0`
`c(time)`	`0.3`

snyder_palmer_moore_2000 — v0.0.1

Snyder, Palmer, Moore, 2000

Details

Parameters:

Name	Description
`k_on2`	`1.3e7`
`Bmax_c`	`0.00012`
`Vmax_s`	`0.000525`
`k_s`	`9.0`
`Kb_c`	`9.6e-7`
`Ca_e`	`0.002`
`k_on1`	`2.0e9`
`V_s`	`0.07`
`K_ons`	`8772.0`
`Bmax_f1`	`0.0002`
`Kb_dye`	`2.0e-7`
`kf`	`2500.0`
`Kb_f2`	`1.3e-5`
`K_offs`	`5.596536`
`V_c`	`0.9287`
`Rt`	`1.5e-7`
`Bmax_f2`	`0.0011`
`Km_s`	`2.5e-7`
`k_off2`	`3.9`
`Vmax_NaCaX`	`0.0012`
`Km_NaCaX`	`3.6e-5`
`k_off1`	`1400.0`
`k1`	`0.2`
`dye_c`	`0.0`
`V_f`	`0.0013`
`Bmax_s`	`0.008`
`Kb_f1`	`1.7e-5`

States:

Name	Description
`Ca_f(time)`	`1.2e-7`
`Ca_CSQ(time)`	`0.0`
`Ca_S2(time)`	`0.0`
`Ca_2_S1(time)`	`0.0`
`S1(time)`	`0.0`
`Ca_c(time)`	`1.0e-7`
`cas2(time)`	`0.0`
`cas1(time)`	`0.0`
`Ca_s(time)`	`0.000201`
`S2(time)`	`0.0`

sobie_dilly_dossantoscruz_lederer_jafri_2002 — v0.0.1

Sobie, Dilly, Dossantoscruz, Lederer, Jafri, 2002

Details

soboleva_vetharaniam_nixon_montenegro_pearson_sneyd_2005 — v0.0.1

Soboleva, Vetharaniam, Nixon, Montenegro, Pearson, Sneyd, 2005

Details

Parameters:

Name	Description
`T`	`9.0`
`delta_U`	`7.5`
`b`	`100.0`
`d01`	`13.0`
`a`	`358000.0`
`P0`	`0.25`
`delta_R`	`1.905`
`ti`	`1.0`
`kappa`	`240000.0`
`alpha0`	`4.15`
`s`	`371000.0`
`delta_x`	`0.207`
`kappa0`	`6550.0`
`delta_b1`	`7.5`
`alpha1`	`3.02`
`G`	`35.6`
`P1`	`20.0`
`PE`	`20.55`
`d12`	`4720.0`
`b0`	`263.0`
`a0`	`23300.0`
`delta_b2`	`50.0`

States:

Name	Description
`B1(time)`	`1.0`
`R(time)`	`1.0`
`B2(time)`	`1.0`
`x(time)`	`0.0`
`U(time)`	`1.0`

spiro_parkinson_othmer_1997 — v0.0.1

Spiro, Parkinson, Othmer, 1997

Details

Parameters:

Name	Description
`k1c`	`0.17`
`Z`	`40.0`
`k2c`	`0.017`
`k4a`	`10.0`
`k4b`	`17.0`
`k13`	`34.56`
`k9`	`45.0`
`k10`	`48.0`
`k_5`	`70.0`
`k1a`	`10.0`
`k_4`	`30000.0`
`L`	`3.0`
`k8`	`15.0`
`k3a`	`10.0`
`k2b`	`17.0`
`k2a`	`10.0`
`k_y`	`500000.0`
`kb`	`800000.0`
`k_2`	`30000.0`
`Y0`	`20.0`
`k6`	`7.0e7`
`k11`	`0.0`
`k12`	`16.5`
`k1b`	`17.0`
`k_3`	`400000.0`
`B0`	`1.7`
`k_7`	`70.0`
`k4c`	`0.51`
`k3c`	`5.1`
`k_b`	`0.35`
`k7`	`7.0e7`
`k_6`	`70.0`
`k3b`	`17.0`
`ky`	`3.0e7`
`R`	`0.3`
`k5`	`7.0e7`
`k_1`	`400000.0`

States:

Name	Description
`T2pR(time)`	`0.01`
`LT3pR(time)`	`0.01`
`LT2pR(time)`	`0.01`
`T3(time)`	`0.01`
`T2p(time)`	`0.01`
`LT4(time)`	`0.01`
`LT2p(time)`	`0.01`
`LT3p(time)`	`0.01`
`T3pR(time)`	`0.01`
`T4(time)`	`0.01`
`LT2R(time)`	`0.01`
`LT4p(time)`	`0.01`
`LT3(time)`	`0.01`
`LT3R(time)`	`0.01`
`T3p(time)`	`0.01`
`Yp(time)`	`0.01`
`T2R(time)`	`0.01`
`T2(time)`	`0.01`
`LT2(time)`	`0.01`
`T3R(time)`	`0.01`
`T4p(time)`	`0.01`
`Bp(time)`	`0.01`

Spronck_Martens_2012 — v0.0.1

Spronck, 2012

Details

A lumped parameter model of cerebral blood flow control combining 1 cerebral autoregulation and neurovascular coupling

sriram_bernot_kepes_2007 — v0.0.1

Sriram, Bernot, Kepes, 2007

Details

Parameters:

Name	Description
`k_c3`	`0.6`
`j_3`	`0.6`
`v_d3`	`3.0`
`k_m1`	`5.0`
`k_m2`	`5.0`
`j_1`	`0.9`
`v_d2`	`1.052`
`k_d3`	`0.8`
`v_12`	`15.0`
`k_d2`	`0.9`
`k_c1`	`0.2`
`k_c2`	`0.22`
`v_10`	`15.0`
`k_100`	`10.0`
`v_11`	`15.0`
`k_d5`	`0.16`
`k_d6`	`0.16`
`k_d4`	`0.16`
`k_d1`	`0.8`
`k_120`	`10.0`
`j_2`	`0.5`
`k_m3`	`5.0`
`v_d1`	`6.0`
`k_110`	`10.0`
`n`	`2.0`

States:

Name	Description
`C_1(time)`	`0.0`
`T_2(time)`	`5.0`
`T_1(time)`	`6.0`
`C_3(time)`	`0.0`
`T_3(time)`	`1.0`
`C_2(time)`	`0.0`

starbuck_wiley_lauffenburger_1990 — v0.0.1

Starbuck, Wiley, Lauffenburger, 1990

Details

Parameters:

Name	Description
`RT`	`nothing`
`K_DC`	`nothing`
`kuc`	`nothing`
`L`	`nothing`
`kdeg`	`nothing`
`Kcp`	`nothing`
`kf`	`nothing`
`Vvesicle`	`nothing`
`kt`	`nothing`
`Nav`	`nothing`
`kr_`	`nothing`
`ku_`	`nothing`
`ks`	`nothing`
`krec_p`	`nothing`
`kc`	`nothing`
`K_DT`	`nothing`
`fr`	`nothing`
`PT`	`nothing`
`krec_i`	`nothing`
`krec_c`	`nothing`
`kr`	`nothing`
`PT_RT`	`nothing`
`Vendosome`	`nothing`
`lamda`	`nothing`
`plate`	`nothing`
`cell`	`nothing`

States:

Name	Description
`Cs(time)`	`nothing`
`Ts(time)`	`nothing`
`Cii(time)`	`nothing`
`Pi(time)`	`nothing`
`Rii(time)`	`nothing`
`Ps(time)`	`nothing`
`Cic(time)`	`nothing`
`Ric(time)`	`nothing`
`Lo(time)`	`nothing`
`Lii(time)`	`nothing`
`Lic(time)`	`nothing`
`Ti(time)`	`nothing`
`Rs(time)`	`nothing`

stern_song_sham_yang_boheler_rios_1999 — v0.0.1

Stern, Song, Sham, Yang, Boheler, Rios, 1999

Details

Parameters:

Name	Description
`ko`	`35.0`
`ki`	`0.5`
`kim`	`0.005`
`kom`	`0.06`
`Ca`	`0.0001`

States:

Name	Description
`O(time)`	`1.0`
`I(time)`	`1.0`
`R(time)`	`1.0`
`RI(time)`	`1.0`

stewart_aslanidi_noble_noble_boyett_zhang_2009 — v0.0.1

Stewart, Aslanidi, Noble, Noble, Boyett, Zhang, 2009

Details

Parameters:

Name	Description
`T`	`310.0`
`EC`	`1.5`
`P_kna`	`0.03`
`Km_Ca`	`1.38`
`g_bca`	`0.000592`
`K_buf_sr`	`0.3`
`V_rel`	`0.102`
`K_sat`	`0.1`
`Km_Nai`	`87.5`
`g_f_K`	`0.0234346`
`g_to`	`0.08184`
`Cm`	`0.185`
`V_xfer`	`0.0038`
`g_pK`	`0.0146`
`P_NaK`	`2.724`
`K_mNa`	`40.0`
`g_bna`	`0.00029`
`g_Ks`	`0.2352`
`g_K1`	`0.065`
`k3`	`0.06`
`K_pCa`	`0.0005`
`g_Kr`	`0.0918`
`g_sus`	`0.0227`
`k1_prime`	`0.15`
`V_ss`	`5.468e-5`
`Na_o`	`140.0`
`K_buf_ss`	`0.00025`
`min_sr`	`1.0`
`K_up`	`0.00025`
`K_mk`	`1.0`
`max_sr`	`2.5`
`Ca_o`	`2.0`
`g_pCa`	`0.1238`
`V_sr`	`0.001094`
`Buf_ss`	`0.4`
`k4`	`0.005`
`V_c`	`0.016404`
`K_o`	`5.4`
`K_buf_c`	`0.001`
`Buf_sr`	`10.0`
`alpha`	`2.5`
`g_Na`	`130.5744`
`k2_prime`	`0.045`
`Vmax_up`	`0.006375`
`V_leak`	`0.00036`
`Buf_c`	`0.2`
`g_f_Na`	`0.0145654`
`gamma`	`0.35`
`g_CaL`	`3.98e-5`
`K_NaCa`	`1000.0`
`R`	`8314.472`
`F`	`96485.3415`

States:

Name	Description
`d(time)`	`0.000287906256206415`
`Xr1(time)`	`0.00550281999719088`
`V(time)`	`-69.1370441635924`
`h(time)`	`0.190678733735145`
`Ca_ss(time)`	`0.000446818714055411`
`f2(time)`	`0.995474890442185`
`y(time)`	`0.0457562667986602`
`f(time)`	`0.989328560287987`
`K_i(time)`	`136.781894160227`
`R_prime(time)`	`0.991580051907845`
`Xs(time)`	`0.00953708522974789`
`Xr2(time)`	`0.313213286437995`
`r(time)`	`0.00103618091196912`
`j(time)`	`0.238219836154029`
`fCass(time)`	`0.999955429598213`
`m(time)`	`0.0417391656294997`
`Ca_SR(time)`	`3.10836886659417`
`Ca_i(time)`	`0.000101878186157052`
`s(time)`	`0.96386101799501`
`Na_i(time)`	`8.80420286531673`

sthilaire_gronfier_zeitzer_klerman_2007 — v0.0.1

Sthilaire, Gronfier, Zeitzer, Klerman, 2007

Details

Parameters:

Name	Description
`betaIS`	`0.065`
`tau_x`	`24.2`
`betaCP`	`0.025`
`k`	`0.55`
`alpha`	`0.067`
`I0`	`9500.0`
`G`	`37.0`
`betaIP`	`0.047`
`mu`	`0.13`
`beta`	`0.007`
`alph_0`	`0.1`
`Amax`	`4.834`
`m`	`7.0`
`betaCS`	`0.028`
`lamda`	`0.588`
`t_off`	`29.867`
`q`	`0.333333`
`p`	`0.6`
`t_on`	`21.93`

States:

Name	Description
`H1(time)`	`nothing`
`xc(time)`	`nothing`
`H3(time)`	`nothing`
`A(time)`	`nothing`
`n(time)`	`nothing`
`I(time)`	`nothing`
`x(time)`	`nothing`
`H2(time)`	`nothing`
`A_(time)`	`nothing`

stilianakis_dietz_schenzle_1997 — v0.0.1

Stilianakis, Dietz, Schenzle, 1997

Details

Parameters:

Name	Description
`X0`	`1.0e11`
`b`	`1.0`
`mu2`	`1.0`
`Kmax`	`20.0`
`mu0`	`0.004`
`a`	`1.0`
`rho`	`0.5`
`beta`	`1000.0`
`theta`	`1.0e-6`
`C1`	`0.04`
`C2`	`1000.0`
`omega`	`1.0e-16`
`lamda`	`4.0e8`
`mu1`	`0.3`

States:

Name	Description
`Z(time)`	`0.0`
`K(time)`	`1.35e-14`
`V(time)`	`1.0`
`X(time)`	`1.0e11`
`Y(time)`	`1.0`

Sulman_et_al_2008 — v0.0.1

Sulman et al. 2008

Details

Parameters:

Name	Description
`stim_start`	`0.06`
`n_NaK`	`1.5`
`alpha_P_lengthening`	`16.0`
`length`	`74.0`
`d_NaCa`	`0.0`
`alpha_2`	`14.6`
`flag_ingib`	`0.0`
`b_2_on`	`1000.0`
`Km_f2ds`	`0.001`
`delta_f`	`0.0001`
`a_on`	`70000.0`
`E_fibro_stretch`	`0.0`
`g_Kr1`	`0.0021`
`g_fibro`	`0.0002`
`K_cyca`	`0.00015`
`m_0`	`0.9`
`K_mNa`	`24.2`
`beta_S_shortening`	`0.0`
`g_bna`	`0.0006`
`kappa_0`	`3.0`
`g_1`	`0.6`
`g_Ks`	`0.0026`
`beta_Q`	`5.0`
`P_Ca_L`	`0.1`
`K_srca`	`0.5`
`F_afterload`	`2.0`
`alpha_G`	`1.0`
`Na_o`	`140.0`
`V_ds_ratio`	`0.1`
`speed_d`	`3.0`
`Kdecay`	`10.0`
`K_m_rel`	`10000.0`
`B_1_tot`	`0.08`
`a_off`	`200.0`
`pi_min`	`0.03`
`b_2_off`	`3.0`
`v_max`	`5.5`
`kappa`	`0.705`
`K_m_Ca_ds`	`0.01`
`radius`	`12.0`
`beta_CaS`	`32500.0`
`K_m_Ca_cyt`	`0.0005`
`K_xcs`	`0.4`
`isotonic`	`0.0`
`P_CaK`	`0.002`
`K_mK`	`1.0`
`q_4`	`15.0`
`speed_f`	`0.3`
`alpha_CaS`	`50000.0`
`beta_P_shortening`	`0.0015`
`stim_amplitude`	`-3.0`
`alpha_P_shortening`	`16.0`
`Km_f2`	`100000.0`
`P_CaNa`	`0.01`
`c_fibro`	`1.0e-5`
`alpha_P`	`4.0`
`F`	`96485.3415`
`K_b`	`4.0`
`T`	`310.0`
`g_Kr2`	`0.0013`
`P_kna`	`0.03`
`k_A`	`40.0`
`x_st`	`0.964285`
`g_bca`	`0.00025`
`g_fibro_stretch`	`0.0`
`alpha_up`	`1.0`
`S_0`	`1.14`
`g_2`	`0.52`
`i_NaK_max`	`0.7`
`a_tr`	`15.0`
`beta_P_lengthening`	`0.0015`
`g_to`	`0.006`
`Cm`	`9.5e-5`
`beta_up`	`0.03`
`FRiNaCa`	`0.001`
`K_kna`	`20.0`
`FrICa`	`1.0`
`SRLeak`	`0.05`
`beta_2`	`0.0018`
`g_K1`	`0.5`
`delta_m`	`1.0e-5`
`beta_3`	`0.015`
`b_1_off`	`182.0`
`V_e_ratio`	`0.4`
`V_i_ratio`	`0.49`
`alpha_S_shortening`	`39.0`
`stim_duration`	`0.0025`
`g_tos`	`0.0`
`A_tot`	`0.07`
`n_NaCa`	`3.0`
`g_K_Na`	`0.0`
`Ca_o`	`2.0`
`q_3`	`17.3`
`a`	`0.25`
`mu`	`3.0`
`R_decay`	`20.0`
`stim_period`	`1.0`
`stim_end`	`10000.0`
`l_0`	`0.525139356105856`
`alpha_Q`	`10.0`
`g_fibro_junct`	`0.00029`
`k_mu`	`0.6`
`q_1`	`17.3`
`K_inh`	`4.0`
`K_mk1`	`10.0`
`lambda`	`30.0`
`V_up_ratio`	`0.03`
`b_1_on`	`100000.0`
`alpha_3`	`48.0`
`V_rel_ratio`	`0.003`
`g_Na`	`2.5`
`alpha_1`	`14.6`
`q_2`	`259.0`
`g_pna`	`0.004`
`alpha_S_lengthening`	`46.0`
`beta_S_lengthening`	`0.0`
`CaS_tot`	`40.0`
`beta_1`	`0.84`
`d_h`	`0.5`
`B_2_tot`	`0.1`
`gamma`	`0.5`
`k_NaCa`	`0.0005`
`R`	`8314.472`

States:

Name	Description
`V_fibro(time)`	`-20.0`
`l_3(time)`	`0.088805830771694`
`xs(time)`	`0.001`
`v(time)`	`0.0`
`f(time)`	`1.0`
`ActFrac(time)`	`0.001914`
`ProdFrac(time)`	`0.2854569`
`K_o(time)`	`3.988`
`m(time)`	`0.0015`
`l_1(time)`	`0.436333342969918`
`s(time)`	`0.997044616031121`
`Na_i(time)`	`5.18787513289509`
`w(time)`	`0.0`
`d(time)`	`0.0`
`xr2(time)`	`1.53745791069154e-7`
`Ca_rel(time)`	`0.989665`
`l_2(time)`	`0.436333525334166`
`h(time)`	`0.995`
`V(time)`	`-93.658148`
`f2(time)`	`1.0`
`K_i(time)`	`139.054`
`N(time)`	`7.455e-8`
`B_1(time)`	`0.0`
`Ca_ds(time)`	`2.55e-6`
`r(time)`	`1.63117173173398e-8`
`B_2(time)`	`0.0`
`A(time)`	`0.00015`
`xr1(time)`	`8.88859784542779e-6`
`Ca_i(time)`	`6.15e-6`
`Ca_up(time)`	`0.994579`
`f2ds(time)`	`0.997`

surkis_peskin_tranchina_leonard_1998 — v0.0.1

Surkis, Peskin, Tranchina, Leonard, 1998

Details

sveiczer_csikasznagy_gyorffy_tyson_novak_2000 — v0.0.1

Sveiczer, Csikasznagy, Gyorffy, Tyson, Novak, 2000

Details

Parameters:

Name	Description
`Jmikr`	`0.15`
`Vwee`	`10.0`
`epsilon_p`	`0.025`
`kaa_`	`0.01`
`Vpyp`	`0.07`
`k25`	`1.0`
`V2_`	`0.02`
`V25_`	`0.05`
`kai`	`0.1`
`k25r_`	`0.4`
`kir`	`0.5`
`k6_`	`0.1`
`Jwee`	`0.2`
`kad`	`0.1`
`kwr`	`1.0`
`kste9r_`	`0.03`
`kmr`	`5.0`
`Vmik`	`2.0`
`kste9r`	`8.0`
`Y`	`0.0`
`Jmik`	`0.15`
`k3`	`0.1`
`km`	`1.0`
`epsilon`	`0.05`
`Jste9r`	`0.01`
`K`	`0.06`
`kpp`	`100.0`
`kwr_`	`0.4`
`kmr_`	`0.01`
`Vwee_`	`0.08`
`Jweer`	`0.2`
`Pyp3`	`1.0`
`J25r`	`0.05`
`mu`	`0.00462`
`V2c`	`0.5`
`V2`	`1.0`
`ki`	`50.0`
`k6`	`5.0`
`Vmik_`	`0.04`
`J25`	`0.05`
`ks`	`0.1`
`kpp_`	`1.0`
`k25r`	`2.0`
`kp`	`100.0`
`V2c_`	`0.02`
`kaa`	`0.1`
`V4`	`1.0`
`kj`	`400.0`
`k1`	`0.02`
`kste9`	`5.0`
`Jste9`	`0.01`
`kw`	`2.0`
`kas`	`0.1`
`SK`	`0.018`
`V25`	`10.0`
`k5`	`0.1`
`V4_`	`0.01`
`kjr`	`1.0`

States:

Name	Description
`Inh(time)`	`0.0`
`Cdc25(time)`	`0.0`
`R_dna(time)`	`1.0`
`Mik1(time)`	`0.0`
`Rum1(time)`	`0.0`
`preMPF(time)`	`1.0`
`Wee1(time)`	`0.0`
`Slp1(time)`	`0.0`
`Rum1P(time)`	`0.0`
`CRP(time)`	`0.0`
`Slp1_a(time)`	`0.0`
`PI(time)`	`0.2`
`mass(time)`	`1.0`
`MPF(time)`	`0.0`
`Ste9(time)`	`0.0`
`CR(time)`	`0.0`

SVP_Templates200906 — v0.0.1

Standard Virtual Parts Template Models v200906

Details

Templates for the Standard Virtual Parts Library, v200906

swanson_true_lin_buhler_vessella_murray_2001 — v0.0.1

Swanson, True, Lin, Buhler, Vessella, Murray, 2001

Details

Parameters:

Name	Description
`beta_h`	`0.0`
`Vo`	`20.0`
`Vh`	`0.0`
`gamma`	`1.2896`
`beta_c`	`1.721`
`rho`	`0.0655`

States:

Name	Description
`p(time)`	`0.0`

swat_2004 — v0.0.1

Bifurcation analysis of the regulatory modules of the mammalian G1/S transition

Details

MOTIVATION: Mathematical models of the cell cycle can contribute to an understanding of its basic mechanisms. Modern simulation tools make the analysis of key components and their interactions very effective. This paper focuses on the role of small modules and feedbacks in the gene-protein network governing the G1/S transition in mammalian cells. Mutations in this network may lead to uncontrolled cell proliferation. Bifurcation analysis helps to identify the key components of this extremely complex interaction network. RESULTS: We identify various positive and negative feedback loops in the network controlling the G1/S transition. It is shown that the positive feedback regulation of E2F1 and a double activator-inhibitor module can lead to bistability. Extensions of the core module preserve the essential features such as bistability. The complete model exhibits a transcritical bifurcation in addition to bistability. We relate these bifurcations to the cell cycle checkpoint and the G1/S phase transition point. Thus, core modules can explain major features of the complex G1/S network and have a robust decision taking function.

Parameters:

Name	Description
`j13`	`0.002`
`k76`	`0.1`
`Fm`	`0.0`
`k25`	`0.9`
`j18`	`0.6`
`km1`	`0.5`
`j12`	`5.0`
`phi_pRBpp`	`0.04`
`j11`	`0.5`
`phi_CycDi`	`0.023`
`a`	`0.04`
`j15`	`0.001`
`k89`	`0.07`
`phi_pRB`	`0.005`
`phi_E2F1`	`0.1`
`phi_pRBp`	`0.06`
`k61`	`0.3`
`km4`	`0.3`
`phi_CycDa`	`0.03`
`k67`	`0.7`
`j61`	`5.0`
`k98`	`0.01`
`j68`	`7.0`
`kp`	`0.05`
`k23`	`0.3`
`phi_CycEi`	`0.06`
`k16`	`0.4`
`km9`	`0.005`
`k43`	`0.01`
`k1`	`1.0`
`j62`	`8.0`
`j65`	`6.0`
`k3`	`0.05`
`k28`	`0.06`
`km2`	`4.0`
`phi_CycEa`	`0.05`
`phi_AP1`	`0.01`
`j63`	`2.0`
`k2`	`1.6`
`k34`	`0.04`

States:

Name	Description
`pRBp(time)`	`0.0`
`CycEa(time)`	`0.0`
`E2F1(time)`	`0.0`
`CycDa(time)`	`0.0`
`pRBpp(time)`	`0.0`
`CycDi(time)`	`0.0`
`pRB(time)`	`0.0`
`AP1(time)`	`0.0`
`CycEi(time)`	`0.0`

SystemsModelTutorial1 — v0.0.1

Tutorial on Constructing a Systems Model from SVPs

Details

T

tabak_mascagni_bertram_2010 — v0.0.1

Tabak, Mascagni and Bertram 2010

Details

Parameters:

Name	Description
`wi`	`0.0`
`ka`	`-0.05`
`n`	`0.01`
`w`	`0.8`
`taus`	`250.0`
`th0`	`0.17`
`ths`	`0.2`
`ks`	`0.05`

States:

Name	Description
`a(time)`	`0.1`
`s(time)`	`0.3`

tabak_toporikova_freeman_bertram_2007 — v0.0.1

Tabak, Toporikova, Freeman, Bertram, 2007

Details

Parameters:

Name	Description
`sh`	`5.0`
`C`	`10.0`
`VK`	`-75.0`
`vn`	`-5.0`
`gSK`	`1.7`
`lambda`	`0.7`
`sm`	`12.0`
`ks`	`0.5`
`gK`	`4.0`
`tau_h`	`20.0`
`tau_n`	`30.0`
`kc`	`0.16`
`alpha`	`0.0015`
`gA`	`25.0`
`fc`	`0.01`
`sn`	`10.0`
`vh`	`-60.0`
`gCa`	`2.0`
`kPRL`	`1.0`
`sf`	`5.6`
`va`	`-20.0`
`vm`	`-20.0`
`sa`	`10.0`
`gBK`	`0.2`
`vf`	`-20.0`
`VCa`	`50.0`

States:

Name	Description
`V(time)`	`-60.0`
`n(time)`	`0.1`
`h(time)`	`0.1`
`Ca(time)`	`0.1`

tentusscher_noble_noble_panfilov_2004 — v0.0.1

Tentusscher, Noble, Noble, Panfilov, 2004

Details

Parameters:

Name	Description
`T`	`310.0`
`stim_start`	`10.0`
`P_kna`	`0.03`
`Km_Ca`	`1.38`
`c_rel`	`0.008232`
`g_bca`	`0.000592`
`K_buf_sr`	`0.3`
`K_sat`	`0.1`
`Km_Nai`	`87.5`
`tau_g`	`2.0`
`a_rel`	`0.016464`
`g_to`	`0.073`
`Cm`	`0.185`
`g_pK`	`0.0146`
`P_NaK`	`1.362`
`K_mNa`	`40.0`
`g_bna`	`0.00029`
`b_rel`	`0.25`
`g_Ks`	`0.245`
`g_K1`	`5.405`
`K_pCa`	`0.0005`
`g_Kr`	`0.096`
`Na_o`	`140.0`
`stim_duration`	`1.0`
`K_up`	`0.00025`
`K_mk`	`1.0`
`Ca_o`	`2.0`
`g_pCa`	`0.825`
`stim_period`	`1000.0`
`V_sr`	`0.001094`
`V_c`	`0.016404`
`K_o`	`5.4`
`K_buf_c`	`0.001`
`Buf_sr`	`10.0`
`alpha`	`2.5`
`g_Na`	`14.838`
`Vmax_up`	`0.000425`
`stim_amplitude`	`52.0`
`V_leak`	`8.0e-5`
`Buf_c`	`0.15`
`gamma`	`0.35`
`g_CaL`	`0.000175`
`K_NaCa`	`1000.0`
`R`	`8314.472`
`F`	`96485.3415`

States:

Name	Description
`d(time)`	`0.0`
`g(time)`	`1.0`
`Xr1(time)`	`0.0`
`V(time)`	`-86.2`
`h(time)`	`0.75`
`f(time)`	`1.0`
`K_i(time)`	`138.3`
`Xs(time)`	`0.0`
`fCa(time)`	`1.0`
`Xr2(time)`	`1.0`
`r(time)`	`0.0`
`j(time)`	`0.75`
`m(time)`	`0.0`
`Ca_SR(time)`	`0.2`
`Ca_i(time)`	`0.0002`
`s(time)`	`1.0`
`Na_i(time)`	`11.6`

tentusscher_noble_noble_panfilov_2006 — v0.0.1

Tentusscher, Noble, Noble, Panfilov, 2006

Details

Parameters:

Name	Description
`T`	`310.0`
`P_kna`	`0.03`
`Km_Ca`	`1.38`
`c_rel`	`0.008232`
`g_bca`	`0.000592`
`K_buf_sr`	`0.3`
`K_sat`	`0.1`
`Km_Nai`	`87.5`
`tau_g`	`2.0`
`a_rel`	`0.016464`
`g_to`	`0.073`
`Cm`	`0.185`
`g_pK`	`0.0146`
`P_NaK`	`1.362`
`IstimPulseDuration`	`1.0`
`K_mNa`	`40.0`
`g_bna`	`0.00029`
`b_rel`	`0.25`
`g_Ks`	`0.245`
`g_K1`	`5.405`
`K_pCa`	`0.0005`
`g_Kr`	`0.096`
`Na_o`	`140.0`
`K_up`	`0.00025`
`K_mk`	`1.0`
`Ca_o`	`2.0`
`g_pCa`	`0.825`
`V_sr`	`0.001094`
`V_c`	`0.016404`
`K_o`	`5.4`
`K_buf_c`	`0.001`
`Buf_sr`	`10.0`
`IstimAmplitude`	`-52.0`
`alpha`	`2.5`
`g_Na`	`14.838`
`Vmax_up`	`0.000425`
`IstimEnd`	`50000.0`
`V_leak`	`8.0e-5`
`Buf_c`	`0.15`
`IstimPeriod`	`1000.0`
`gamma`	`0.35`
`g_CaL`	`0.000175`
`K_NaCa`	`1000.0`
`IstimStart`	`100.0`
`R`	`8314.472`
`F`	`96485.3415`

States:

Name	Description
`d(time)`	`0.0`
`g(time)`	`1.0`
`Xr1(time)`	`0.0`
`V(time)`	`-86.2`
`h(time)`	`0.75`
`f(time)`	`1.0`
`K_i(time)`	`138.3`
`Xs(time)`	`0.0`
`fCa(time)`	`1.0`
`Xr2(time)`	`1.0`
`r(time)`	`0.0`
`j(time)`	`0.75`
`m(time)`	`0.0`
`Ca_SR(time)`	`0.2`
`Ca_i(time)`	`0.0002`
`s(time)`	`1.0`
`Na_i(time)`	`11.6`

tentusscher_panfilov_2006 — v0.0.1

Tentusscher, Panfilov, 2006

Details

Parameters:

Name	Description
`T`	`310.0`
`stim_start`	`10.0`
`EC`	`1.5`
`P_kna`	`0.03`
`Km_Ca`	`1.38`
`g_bca`	`0.000592`
`K_buf_sr`	`0.3`
`V_rel`	`0.102`
`K_sat`	`0.1`
`Km_Nai`	`87.5`
`g_to`	`0.294`
`Cm`	`0.185`
`V_xfer`	`0.0038`
`g_pK`	`0.0146`
`P_NaK`	`2.724`
`K_mNa`	`40.0`
`g_bna`	`0.00029`
`g_Ks`	`0.392`
`g_K1`	`5.405`
`k3`	`0.06`
`K_pCa`	`0.0005`
`g_Kr`	`0.153`
`k1_prime`	`0.15`
`V_ss`	`5.468e-5`
`Na_o`	`140.0`
`stim_duration`	`1.0`
`K_buf_ss`	`0.00025`
`min_sr`	`1.0`
`K_up`	`0.00025`
`K_mk`	`1.0`
`max_sr`	`2.5`
`Ca_o`	`2.0`
`g_pCa`	`0.1238`
`stim_period`	`1000.0`
`V_sr`	`0.001094`
`Buf_ss`	`0.4`
`k4`	`0.005`
`V_c`	`0.016404`
`K_o`	`5.4`
`K_buf_c`	`0.001`
`Buf_sr`	`10.0`
`alpha`	`2.5`
`g_Na`	`14.838`
`k2_prime`	`0.045`
`Vmax_up`	`0.006375`
`stim_amplitude`	`52.0`
`V_leak`	`0.00036`
`Buf_c`	`0.2`
`gamma`	`0.35`
`g_CaL`	`3.98e-5`
`K_NaCa`	`1000.0`
`R`	`8314.472`
`F`	`96485.3415`

States:

Name	Description
`d(time)`	`3.373e-5`
`Xr1(time)`	`0.00621`
`V(time)`	`-85.23`
`h(time)`	`0.7444`
`Ca_ss(time)`	`0.00036`
`f2(time)`	`0.9755`
`f(time)`	`0.7888`
`K_i(time)`	`136.89`
`R_prime(time)`	`0.9073`
`Xs(time)`	`0.0095`
`Xr2(time)`	`0.4712`
`r(time)`	`2.42e-8`
`j(time)`	`0.7045`
`fCass(time)`	`0.9953`
`m(time)`	`0.00172`
`Ca_SR(time)`	`3.64`
`Ca_i(time)`	`0.000126`
`s(time)`	`0.999998`
`Na_i(time)`	`8.604`

terkildsen_niederer_crampin_hunter_smith_2008 — v0.0.1

Terkildsen, Niederer, Crampin, Hunter, Smith, 2008

Details

Parameters:

Name	Description
`c`	`0.01`
`T`	`295.0`
`K_m_K`	`1.5`
`A_1`	`-29.0`
`B_CMDN`	`0.05`
`alpha_2`	`0.13`
`i_NaK_max`	`9.5e-5`
`K_L`	`0.00022`
`k_on`	`100.0`
`d`	`100.0`
`k_Ref_off`	`0.2`
`g_B_K`	`1.38e-7`
`Cm`	`0.0001`
`theta_R`	`0.012`
`alpha_r2`	`0.00175`
`k_sat`	`0.1`
`K_mNa`	`87.5`
`eta`	`0.35`
`J_L`	`0.000913`
`V_L`	`-2.0`
`J_R`	`0.02`
`V_myo`	`25850.0`
`g_K1`	`2.4e-5`
`del_VL`	`7.0`
`K_mCa`	`1.38`
`A_3`	`129.0`
`alpha_0`	`0.008`
`tau_R`	`2.43`
`a_endo`	`0.583`
`T_ref`	`56.2`
`phi_R`	`0.05`
`Na_o`	`140.0`
`Ca_50ref`	`0.00105`
`stim_duration`	`10.0`
`E_Ca`	`65.0`
`n_Hill`	`3.0`
`z_p`	`0.85`
`b`	`14.0`
`g_B_Na`	`8.015e-8`
`g_ss`	`7.0e-6`
`Ca_o`	`1.2`
`K_z`	`0.15`
`V_SR`	`2098.0`
`g_pCa`	`3.5e-6`
`K_mpCa`	`0.0005`
`a`	`0.0625`
`k_CMDN`	`0.002382`
`g_D`	`0.065`
`stim_period`	`1000.0`
`b_endo`	`0.417`
`N`	`50000.0`
`alpha_r1`	`0.002`
`f_Na`	`0.2`
`K_o`	`5.4`
`g_NCX`	`0.0385`
`A_2`	`138.0`
`beta_0`	`4.9`
`K_m_Na`	`10.0`
`n_Rel`	`3.0`
`alpha_3`	`0.625`
`K_SERCA`	`0.0005`
`g_t`	`3.5e-5`
`g_SERCA`	`0.00045`
`V_SR_uL`	`2.098e-6`
`Ca_TRPN_Max`	`0.07`
`g_Na`	`0.0008`
`g_B_Ca`	`3.24e-5`
`gamma_trpn`	`2.0`
`g_f`	`1.45e-6`
`alpha_1`	`0.03`
`stim_amplitude`	`-0.0006`
`tau_L`	`650.0`
`K_RyR`	`0.041`
`phi_L`	`2.35`
`beta_1`	`-4.0`
`g_CaB`	`2.6875e-8`
`g_SRl`	`1.8951e-5`
`R`	`8314.5`
`t_L`	`1.0`
`F`	`96487.0`
`V_myo_uL`	`2.585e-5`

States:

Name	Description
`z_1(time)`	`0.98794`
`y(time)`	`0.0026369`
`z_2(time)`	`0.00887`
`s_slow(time)`	`0.42756`
`j(time)`	`0.60876276`
`Q_3(time)`	`0.0`
`z_3(time)`	`0.003156`
`m(time)`	`0.0054828`
`s(time)`	`0.8823`
`Na_i(time)`	`11.28`
`V(time)`	`-78.8`
`TRPN(time)`	`0.0661796`
`h(time)`	`0.6095126`
`r_ss(time)`	`0.0033545`
`s_ss(time)`	`0.266596`
`z(time)`	`0.020023`
`K_i(time)`	`138.7225`
`Q_2(time)`	`0.0`
`r(time)`	`0.002542`
`Ca_SR(time)`	`0.72196`
`Ca_i(time)`	`0.00011423`
`Q_1(time)`	`0.0`

testing-Sed-ML-nesting: testing_Sed_ML_nesting — v0.0.1

Some test SED-ML to play with the nested proposal

Details

A place to store and track SED-ML documents which demonstrate various aspects of the various proposals to extend SED-ML with nested tasks and/or simulations.

teusink_passarge_reijenga_esgalhado_vanderweijden_schepper_walsh_bakker_vandam_westerhoff_snoep_2000 — v0.0.1

Teusink, Passarge, Reijenga, Esgalhado, Vanderweijden, Schepper, Walsh, Bakker, Vandam, Westerhoff, Snoep, 2000

Details

tham_2008 — v0.0.1

Tham 2008

Details

thomas_2000 — v0.0.1

Thomas, 2000

Details

Parameters:

Name	Description
`sigma_GLU`	`0.5`
`b`	`4.0`
`sigma_LAC`	`0.5`
`Km`	`0.1`
`ksh`	`1.213`
`L`	`4.0`
`PGLU`	`1.2`
`PLAC`	`33.93`
`VolFract`	`0.3`
`GlyFract`	`0.2`
`c_DVR_GLU_0`	`10.0`
`N_0`	`128.0`

States:

Name	Description
`F_AVR_GLU(x)`	`0.01`
`F_DVR_v(x)`	`3.75`
`F_DVR_GLU(x)`	`0.01`
`F_AVR_v(x)`	`0.01`
`F_DVR_LAC(x)`	`0.01`
`F_AVR_LAC(x)`	`0.01`

thomsen_neubig_1989 — v0.0.1

Thomsen, Neubig, 1989

Details

Parameters:

Name	Description
`GDP`	`nothing`
`k4_`	`nothing`
`k1`	`nothing`
`k3_`	`nothing`
`GTP`	`nothing`
`k2_`	`nothing`
`k4`	`nothing`
`k3`	`nothing`
`k6`	`nothing`
`k5`	`nothing`
`k1_`	`nothing`
`k2`	`nothing`

States:

Name	Description
`DR(time)`	`nothing`
`DRG_GDP(time)`	`nothing`
`G_GDP(time)`	`nothing`
`DRG_GTP(time)`	`nothing`
`DRG(time)`	`nothing`
`R(time)`	`nothing`
`D(time)`	`nothing`
`Gstar_GTP(time)`	`nothing`

tolic_mosekilde_sturis_2000 — v0.0.1

Tolic, Mosekilde, Sturis, 2000

Details

Parameters:

Name	Description
`C3`	`1000.0`
`Rm`	`210.0`
`td`	`36.0`
`a1`	`300.0`
`Gin`	`216.0`
`Ub`	`72.0`
`alpha`	`0.29`
`C4`	`80.0`
`E`	`0.2`
`Um`	`940.0`
`beta`	`1.77`
`C1`	`2000.0`
`C2`	`144.0`
`tp`	`6.0`
`ti`	`100.0`
`U0`	`40.0`
`Vp`	`3.0`
`C5`	`26.0`
`Vg`	`10.0`
`Rg`	`180.0`
`Vi`	`11.0`

States:

Name	Description
`Ii(time)`	`243.2865183`
`x3(time)`	`104.5878705`
`G(time)`	`12342.61665`
`x2(time)`	`112.7601171`
`Ip(time)`	`93.36441699`
`x1(time)`	`110.420253`

tomida_hirose_takizawa_shibasaki_iino_2003 — v0.0.1

Tomida, Hirose, Takizawa, Shibasaki, Iino, 2003

Details

Parameters:

Name	Description
`stim_duration`	`0.5`
`k3`	`0.06`
`k4`	`0.035`
`stim_wavelength`	`3.0`
`k1_unstim`	`0.0`
`k1_stim`	`0.359`
`k2`	`0.147`
`time_before_stim`	`1.0`

States:

Name	Description
`NFAT_cyt(time)`	`0.0`
`NFAT_nuc(time)`	`0.0`
`NFATP_cyt(time)`	`5000.0`

topp_promislow_devries_miura_finegood_2000 — v0.0.1

Topp, Promislow, Devries, Miura, Finegood, 2000

Details

Parameters:

Name	Description
`SI`	`0.72`
`sigma`	`43.2`
`r1`	`0.00084`
`r2`	`2.4e-6`
`d0`	`0.06`
`alpha`	`2000.0`
`k`	`432.0`
`R0`	`846.0`
`EG0`	`1.44`

States:

Name	Description
`G(time)`	`600.0`
`I(time)`	`0.0`
`beta(time)`	`0.0`

tran_2009 — v0.0.1

Tran 2010

Details

A metabolite-sensitive, thermodynamically-constrained model of cardiac cross-bridge cycling: Implications for force development during ischemia, Kenneth Tran, Nicolas P. Smith, Denis S. Loiselle and Edmund J. Crampin, 2010, Biophysical Journal, 98, 267-276. PubMed ID: 20338848

Parameters:

Name	Description
`koffH`	`0.025`
`kn_p`	`0.5`
`SEon`	`1.0`
`perm50`	`0.5`
`koffL`	`0.25`
`hb`	`0.4`
`hfmdc`	`5.0`
`gslmod`	`6.0`
`hbmdc`	`0.0`
`kMgATP`	`1.54e10`
`pH`	`7.15`
`fapp`	`0.5`
`Qgapp`	`2.5`
`len_hbare`	`0.1`
`MgATP_cons`	`5000.0`
`len_thick`	`1.65`
`kdADP`	`4.0`
`kp_n`	`0.05`
`Qkn_p`	`1.6`
`kon`	`0.05`
`sigman`	`1.0`
`hf`	`2.0`
`KSE`	`1.0`
`SLrest`	`1.85`
`Cai`	`200.0`
`Qkon`	`1.5`
`Qkp_n`	`1.6`
`Qhf`	`6.25`
`PCon_t`	`0.002`
`MgATP`	`5000.0`
`PCon_c`	`0.02`
`SLset`	`1.9`
`xPi_cons`	`2000.0`
`sigmap`	`8.0`
`gapp`	`0.07`
`gxb`	`0.07`
`len_thin`	`1.2`
`Qkoff`	`1.3`
`PExp_c`	`70.0`
`MgADP_cons`	`36.0`
`xPi`	`2000.0`
`nperm`	`15.0`
`SL_c`	`2.25`
`MgADP`	`36.3`
`TmpC`	`299.0`
`Qgxb`	`6.25`
`x_0`	`0.007`
`koffmod`	`1.0`
`Trop_conc`	`70.0`
`kdHCa`	`0.02`
`xPsi`	`2.0`
`m`	`1.0`
`Qhb`	`6.25`
`xbmodsp`	`0.2`
`Qfapp`	`6.25`
`PExp_t`	`10.0`

States:

Name	Description
`P(time)`	`0.999997834540066`
`TRPNCaL(time)`	`0.0147730085063734`
`P_NoXB(time)`	`4.07437173988636e-8`
`TRPNCaH(time)`	`0.13066096561522`
`SL(time)`	`2.2`
`xXBprer(time)`	`3.41212828972468e-8`
`XBprer(time)`	`3.0494964880038e-7`
`N_NoXB(time)`	`0.999999959256274`
`xXBpostr(time)`	`0.00700005394873882`
`XBpostr(time)`	`1.81017564383744e-6`
`intf(time)`	`-4.5113452510363e-6`

tran_smith_loiselle_crampin_2009 — v0.0.1

Tran, Smith, Loiselle, Crampin, 2009

Details

Parameters:

Name	Description
`P_i`	`1.0`
`ATP`	`5.0`
`kdh1`	`1.09e-5`
`k_m1`	`2.0`
`k_m2`	`67200.0`
`Ca_sr`	`1.0`
`Ca_i`	`0.001`
`H_i`	`0.0001`
`k_p3`	`20.5`
`kdcasr`	`2.24`
`k_p1`	`25900.0`
`k_p2`	`2540.0`
`k_m3`	`149.0`
`kdhsr`	`1.05e-8`
`kdh`	`7.24e-5`
`kdcai`	`0.9`
`ADP`	`0.02`
`kdhi`	`0.00354`
`n`	`2.0`

States:

Name	Description
`Ca_sr(time)`	`0.0`
`ATP(time)`	`0.01`

tyson_1991 — v0.0.1

Tyson, 1991

Details

Parameters:

Name	Description
`k4_`	`0.018`
`k9`	`100.0`
`P`	`1.0`
`k4`	`180.0`
`k7`	`0.6`
`k6`	`1.0`
`aa`	`1.0`
`k2`	`0.0`

States:

Name	Description
`pM(time)`	`0.001`
`CP(time)`	`0.001`
`M(time)`	`0.001`
`YP(time)`	`0.001`
`Y(time)`	`0.001`
`C2(time)`	`0.001`

tyson_hong_thron_novak_1999 — v0.0.1

Tyson, Hong, Thron, Novak, 1999

Details

Parameters:

Name	Description
`vp`	`0.5`
`kp3`	`0.1`
`km`	`0.1`
`kp1`	`10.0`
`vm`	`1.0`
`Jp`	`0.05`
`Pcrit`	`0.1`
`Keq`	`200.0`
`kp2`	`0.03`

States:

Name	Description
`M(time)`	`0.0`
`Pt(time)`	`0.0`

U

ueda_hagiwara_kitano_2001 — v0.0.1

Ueda, Hagiwara, Kitano, 2001

Details

Parameters:

Name	Description
`V3`	`1.63`
`B1`	`0.0`
`L8`	`0.2`
`r`	`4.0`
`T4`	`0.52`
`V1`	`1.45`
`T3`	`1.63`
`S4`	`0.48`
`L6`	`0.2`
`D2`	`0.44`
`S2`	`0.48`
`D7`	`0.54`
`R1`	`1.02`
`K4`	`2.0`
`A3`	`0.8`
`D6`	`0.29`
`T2`	`0.72`
`A1`	`0.45`
`D1`	`0.94`
`K1`	`2.0`
`L1`	`0.3`
`L5`	`0.2`
`C3`	`0.0`
`K2`	`2.0`
`B2`	`0.0`
`L4`	`0.2`
`a`	`1.0`
`L2`	`0.2`
`D9`	`0.6`
`C2`	`0.0`
`C1`	`0.0`
`S1`	`1.45`
`B3`	`0.6`
`A2`	`0.45`
`L3`	`0.3`
`V2`	`1.45`
`D4`	`0.44`
`L9`	`0.2`
`S5`	`1.63`
`D10`	`0.3`
`S3`	`1.45`
`V4`	`1.63`
`Cyc_c`	`1.0`
`Dbt_c`	`1.0`
`L7`	`0.13`
`T1`	`1.73`
`D3`	`0.94`
`R3`	`0.89`
`D8`	`0.6`
`L10`	`0.2`
`S6`	`0.47`
`D5`	`0.44`
`D0`	`0.012`
`R2`	`1.02`
`K3`	`2.0`

States:

Name	Description
`Per_c(time)`	`0.6`
`PT_c(time)`	`0.9`
`CC_c(time)`	`0.3`
`Tim_c(time)`	`0.8`
`Clk_c(time)`	`0.2`
`Clk_m(time)`	`0.1`
`Per_m(time)`	`0.5`
`CC_n(time)`	`0.4`
`PT_n(time)`	`1.0`
`Tim_m(time)`	`0.7`

V

vanbeek_2007 — v0.0.1

Vanbeek, 2007

Details

Parameters:

Name	Description
`PS_tot_ADP`	`13.3`
`V_max_syn`	`15040.0`
`J_hyd_basis_1`	`486.5`
`Kia`	`750.0`
`Vmax_MM_f`	`11440.0`
`Kic`	`204.8`
`PS_tot_PCr`	`155.0`
`KPi`	`800.0`
`nb_of_cycles_1`	`5.0`
`Kb`	`5200.0`
`Kd`	`500.0`
`Vmax_MM_b`	`48040.0`
`PS_tot_Pi`	`194.0`
`Vmax_Mi_b`	`3704.0`
`PS_tot_Cr`	`155.0`
`J_hyd_basis_2`	`627.6`
`freq_1`	`135.0`
`PS_tot_ATP`	`13.3`
`Kid`	`1600.0`
`Vmax_Mi_f`	`882.0`
`V_cyt`	`0.75`
`KADP`	`25.0`
`Kib`	`28800.0`
`V_ims`	`0.0625`
`freq_2`	`220.0`

States:

Name	Description
`PCr_ims(time)`	`5000.0`
`ATP_ims(time)`	`5912.77`
`Pi_ims(time)`	`910.0`
`ADP_ims(time)`	`39.0`
`ATP_cyt(time)`	`5912.77`
`Cr_ims(time)`	`10500.0`
`ADP_cyt(time)`	`64.0`
`PCr_cyt(time)`	`5000.0`
`Cr_cyt(time)`	`10500.0`
`Pi_cyt(time)`	`913.0`

vancapelle_durrer_1980 — v0.0.1

Vancapelle, Durrer, 1980

Details

Parameters:

Name	Description
`T`	`50.0`
`C`	`0.01`
`cf`	`0.2531834`
`df`	`2.356256`
`bf`	`0.00584649`
`Vm`	`-78.6`
`af`	`3.837854e-5`

States:

Name	Description
`Y(time)`	`0.07`

vanderpol_vandermark_1928 — v0.0.1

Vanderpol, Vandermark, 1928

Details

Parameters:

Name	Description
`epsilon`	`1.0`

States:

Name	Description
`x(time)`	`-2.0`
`y(time)`	`0.0`

vangoor_lebeau_krsmanovic_sherman_catt_stojilkovic_2000 — v0.0.1

Vangoor, Lebeau, Krsmanovic, Sherman, Catt, Stojilkovic, 2000

Details

Parameters:

Name	Description
`tau_h`	`22.0`
`i_app`	`15.0`
`g_M`	`4.0`
`g_ir`	`1.71`
`g_d`	`0.044`
`g_Na`	`60.0`
`Vh`	`40.0`
`k1`	`0.3`
`V_K`	`-80.0`
`g_K_dr`	`20.0`
`k2_`	`0.01`
`V_Ca`	`100.0`
`g_Ca_L`	`1.3`
`g_Ca_T`	`0.94`
`V_Na`	`60.0`
`Cm`	`14.0`
`k1_`	`0.03`
`k2`	`0.001`

States:

Name	Description
`D_(time)`	`0.0`
`A(time)`	`1.0`
`n(time)`	`0.0`
`h(time)`	`0.0`
`m(time)`	`0.0`
`V(time)`	`-60.0`
`D(time)`	`0.0`
`A_(time)`	`0.0`

vasalou_henson_2010 — v0.0.1

Vasalou and Henson 2010

Details

Parameters:

Name	Description
`v_Cl2`	`19.0`
`KmB`	`0.4`
`v_Cl1`	`15.5`
`K_D`	`0.08`
`V2PC`	`0.1`
`kdnc`	`0.12`
`kf`	`0.001`
`K_Ca`	`22.0`
`beta_IP3`	`0.5`
`v_PK`	`1.9`
`Cl0`	`1.0`
`E_Na_0`	`45.0`
`K_A`	`0.67`
`v_v0`	`0.09`
`Ca_ex`	`5.0`
`ksC`	`1.6`
`vdPCN`	`0.7`
`V_MK`	`5.0`
`K_VIP`	`15.0`
`v_sP0`	`1.0`
`K_ex2`	`1.0`
`k3`	`0.4`
`E_ex`	`0.0`
`V3PC`	`0.4`
`v_M2`	`149.5`
`v_ex1`	`105.0`
`vdCC`	`0.7`
`kd_VIP`	`0.5`
`nCl`	`-0.2`
`vmB`	`0.8`
`k_q`	`8.75e-5`
`KmP`	`0.31`
`v_gk`	`10.0`
`K_Cl2`	`1.0`
`K_gk`	`10.0`
`GABA0`	`0.2`
`nkk`	`0.1`
`E_L_0`	`-29.0`
`Kd`	`0.3`
`k6`	`0.2`
`vdPCC`	`0.7`
`V2C`	`0.1`
`V4B`	`0.2`
`K_GABA`	`3.0`
`k_MK`	`2.9`
`nd_VIP`	`0.2`
`npk`	`-2.0`
`Cl_ex`	`114.5`
`kdmb`	`0.01`
`V1P`	`0.4`
`k_b`	`2.0`
`K_kk`	`0.02`
`ksB`	`0.12`
`m`	`2.0`
`Na_ex`	`145.0`
`K_ex1`	`5.7405e8`
`P_Cl`	`0.3`
`k2`	`0.2`
`n`	`4.0`
`vdBC`	`0.5`
`F`	`96485.0`
`K_v0`	`4.5`
`vdIN`	`0.8`
`T`	`37.0`
`P_Na`	`0.036`
`V_R`	`0.41`
`V_theta`	`20.0`
`k8`	`0.1`
`vP`	`1.0`
`V2P`	`0.3`
`V3B`	`0.5`
`V4PC`	`0.1`
`v_M1`	`0.0003`
`K2CB`	`0.01`
`vmP`	`1.1`
`v_GABA`	`19.0`
`V1C`	`0.6`
`K_2`	`5.0`
`KmC`	`0.4`
`Cm`	`5.0`
`KAP`	`0.6`
`V1B`	`0.5`
`kdn`	`0.01`
`WT`	`1.0`
`KAC`	`0.6`
`v_kk`	`3.3`
`n_VIP`	`1.9`
`vmC`	`1.0`
`V_b`	`2.0`
`V1PC`	`0.4`
`nex2`	`-1.0`
`K_Cl1`	`4.0`
`K_R`	`34.0`
`vsC`	`1.1`
`vsB`	`1.0`
`T_room`	`22.0`
`nex1`	`2.5`
`v_Ca`	`12.3`
`E_K_0`	`-97.0`
`K1CB`	`0.01`
`v_M3`	`400.0`
`kdmp`	`0.01`
`K_PK`	`1.0`
`ksP`	`0.6`
`V2B`	`0.1`
`v_VIP`	`0.5`
`C_T`	`1.6`
`kdmc`	`0.01`
`Kdp`	`0.1`
`K_ex`	`1.0`
`k4`	`0.2`
`v_KCa`	`3.0`
`vdPC`	`0.7`
`v`	`2.0`
`g_K0`	`9.7`
`K_KCa`	`0.16`
`P_Ca`	`0.05`
`g_Na`	`36.0`
`nkca`	`-1.0`
`Kp`	`0.1`
`nv0`	`4.5`
`k1`	`0.45`
`g_inhib`	`12.3`
`nca`	`2.2`
`K_C`	`0.15`
`KIB`	`2.2`
`k7`	`0.5`
`v_ex2`	`4.4`
`vdBN`	`0.6`
`k5`	`0.4`
`R`	`8.314`
`p`	`4.2`
`T_abs`	`273.15`

States:

Name	Description
`IN(time)`	`0.05`
`BC(time)`	`2.41`
`PCNP(time)`	`0.091`
`BN(time)`	`1.94`
`PCCP(time)`	`0.2`
`PC(time)`	`0.4`
`CB(time)`	`0.12`
`BCP(time)`	`0.48`
`MP(time)`	`2.8`
`CCP(time)`	`9.0`
`VIP(time)`	`0.0`
`Ca_store(time)`	`0.1`
`PCN(time)`	`0.16`
`CC(time)`	`12.0`
`PCP(time)`	`0.13`
`PCC(time)`	`1.26`
`Ca_in(time)`	`0.1`
`MB(time)`	`7.94`
`MC(time)`	`2.0`
`BNP(time)`	`0.32`

vaseghi_baumeister_rizzi_reuss_1999 — v0.0.1

Vaseghi, Baumeister, Rizzi, Reuss, 1999

Details

Parameters:

Name	Description
`K_NADP_2`	`1.848`
`rmax_PKDA`	`0.004`
`rmax_Ru5PE`	`0.85`
`Ki_MgATP_2`	`0.109`
`rmax_G6PDH`	`44.19`
`K_PKDA`	`0.0032`
`K_RPPK`	`0.0034`
`rmax_TAL`	`3.0`
`rmax_TKL1`	`3.24`
`K_NADP_1`	`0.116`
`Ki_MgATP_1`	`0.33`
`Ki_NADPH_2`	`0.055`
`mu`	`1.0`
`C_GAP`	`0.064`
`rmax_R5PI`	`0.57`
`rmax_6PGDH`	`0.654`
`Ki_NADPH_1`	`1.702`
`rmax_TKL2`	`10.5`
`rmax_RPPK`	`0.003`

States:

Name	Description
`C_Ru5P(time)`	`0.033`
`C_R5P(time)`	`0.118`
`C_G6P(time)`	`0.9`
`C_MgATP(time)`	`2.3`
`C_E4P(time)`	`0.029`
`C_NADPH(time)`	`0.168`
`C_S7P(time)`	`0.082`
`C_NADP(time)`	`0.168`
`C_X5P(time)`	`0.041`
`C_6PG(time)`	`0.25`

vempati_karagiannis_popel_2007 — v0.0.1

Vempati, Karagiannis, Popel, 2007

Details

Parameters:

Name	Description
`kon_pM9T1M3`	`34000.0`
`koff_M3pM9`	`0.001`
`kon_M9T1_star`	`5.6e6`
`kon_TrpM9`	`10000.0`
`koff_M3pM9T1`	`0.001`
`koff_pM9T1M3`	`7.48e-5`
`koff_M9T1`	`0.00025`
`kon_M3_pM9T1`	`1.9e6`
`kon_M3T1`	`1.9e6`
`kon_pM9T1`	`34000.0`
`koff_TrpM9T1M3`	`0.007`
`koff_M3_pM9T1`	`0.000126`
`koff_M9T1_star`	`1.6e-5`
`kon_M9_M3T1`	`7.48e-5`
`koff_M9_M3T1`	`34000.0`
`kon_M3pM9T1M3`	`10000.0`
`kact_M3pM9`	`0.0019`
`kact_TrpM9T1`	`0.0006`
`koff_M3T1`	`0.000126`
`kon_TrpM9T1`	`10000.0`
`koff_TrpM9T1`	`0.007`
`koff_pM9T1`	`7.48e-5`
`kon_M3pM9`	`10000.0`
`kon_M9T1`	`0.00063`
`kon_TrpM9T1M3`	`10000.0`
`kact_M3pM9T1`	`0.00057`
`kon_M3pM9T1`	`10000.0`
`koff_TrpM9`	`0.007`
`koff_M3pM9T1M3`	`0.001`
`kact_TrpM9T1M3`	`0.0006`
`kact_M3pM9T1M3`	`0.00057`
`kact_M9T1M3`	`0.000126`
`kact_TrpM9`	`0.002`

States:

Name	Description
`M9_T1_M3(time)`	`0.0`
`pM9_T1(time)`	`0.0`
`pM9_T1_M3(time)`	`0.0`
`M3_pM9(time)`	`0.0`
`M3(time)`	`5.0e-8`
`Tr_pM9(time)`	`0.0`
`M9_T1(time)`	`0.0`
`Tr_pM9_T1(time)`	`0.0`
`M3_pM9_T1_M3(time)`	`0.0`
`M9_T1_star(time)`	`0.0`
`pM9(time)`	`3.0e-7`
`Tr(time)`	`1.0e-7`
`M3_pM9_T1(time)`	`0.0`
`Tr_pM9_T1_M3(time)`	`0.0`
`M9(time)`	`0.0`
`M3_T1(time)`	`0.0`
`T1(time)`	`3.0e-7`

vendelin_kongas_saks_2000 — v0.0.1

Vendelin, Kongas, Saks, 2000

Details

vilar_2006 — v0.0.1

Vilar 2006

Details

Parameters:

Name	Description
`ka`	`1.0`
`kr`	`0.033333333`
`p_RII`	`4.0`
`ki`	`0.333333333`
`kcd`	`0.0277777778`
`klid`	`0.25`
`alpha`	`1.0`
`p_RI`	`8.0`

States:

Name	Description
`RII(time)`	`20.0`
`l_RI_RII_endo(time)`	`40.0`
`RII_endo(time)`	`0.0`
`l_RI_RII(time)`	`0.0`
`RI(time)`	`20.0`
`RI_endo(time)`	`0.0`

vilar_kueh_barkai_leibler_2002 — v0.0.1

Vilar, Kueh, Barkai, Leibler, 2002

Details

Parameters:

Name	Description
`Delta_1`	`1.0`
`Delta_4`	`10.0`
`Delta_3`	`0.2`
`Thetha_1`	`50.0`
`Delta_2`	`1.0`
`Gamma_1`	`2.0`
`Delta_5`	`0.5`
`Alpha_2`	`500.0`
`Gamma_2`	`1.0`
`Gamma_3`	`1.0`
`BetaR_1`	`5.0`
`Alpha_1`	`50.0`
`Alpha_3`	`0.01`
`BetaA_1`	`50.0`
`Alpha_4`	`50.0`
`Theta_2`	`100.0`

States:

Name	Description
`DR(time)`	`1.0`
`DA(time)`	`1.0`
`MR(time)`	`0.0`
`A(time)`	`0.0`
`R(time)`	`0.0`
`DRP(time)`	`1.0`
`MA(time)`	`0.0`
`C(time)`	`0.0`
`DAp(time)`	`0.0`

vinnakota_kemp_kushmerick_2006 — v0.0.1

Vinnakota, Kemp and Kushmerick, 2006

Details

Parameters:

Name	Description
`T1`	`298.15`
`R`	`0.008314`

States:

Name	Description
`PEP(time)`	`1.0e-9`
`G6P(time)`	`1.0e-9`
`Pi(time)`	`0.035`
`G3P(time)`	`1.0e-9`
`Mg(time)`	`0.0004913450725`
`Gly(time)`	`0.04`
`Cr(time)`	`0.029999999`
`AMP(time)`	`1.0e-9`
`P3G(time)`	`1.0e-9`
`ATP(time)`	`0.005`
`pH_calc(time)`	`7.3`
`F6P(time)`	`1.0e-9`
`FBP(time)`	`1.0e-9`
`G1P(time)`	`1.0e-9`
`ADP(time)`	`1.0e-9`
`BPG(time)`	`1.0e-9`
`PCr(time)`	`1.0e-9`
`PYR(time)`	`1.0e-9`
`GAP(time)`	`1.0e-9`
`NAD(time)`	`0.0005`
`protonload(time)`	`0.0`
`DHAP(time)`	`1.0e-9`
`LAC(time)`	`1.0e-9`
`P2G(time)`	`1.0e-9`
`NADH(time)`	`1.0e-9`

vinnakota_rusk_palmer_shankland_kushmerick_2010 — v0.0.1

Vinnakota, Rusk, Palmer, Shankland and Kushmerick, 2010

Details

Parameters:

Name	Description
`clamp`	`1.0`

States:

Name	Description
`PEP(time)`	`1.0e-9`
`G6P(time)`	`1.0e-9`
`Pi(time)`	`0.0054`
`G3P(time)`	`1.0e-9`
`mg(time)`	`0.001`
`Gly(time)`	`0.02`
`Cr(time)`	`0.0075`
`AMP(time)`	`1.0e-8`
`HCO3_cy(time)`	`0.015`
`P3G(time)`	`1.0e-9`
`HCO3_ec(time)`	`0.03`
`ATP(time)`	`0.0055`
`pH_ec(time)`	`7.439766507222684`
`pH_calc(time)`	`7.14`
`F6P(time)`	`1.0e-9`
`FBP(time)`	`1.0e-9`
`G1P(time)`	`1.0e-9`
`ADP(time)`	`1.0e-5`
`BPG(time)`	`1.0e-9`
`CO2_ec(time)`	`0.001564425`
`PCr(time)`	`0.0145`
`PYR(time)`	`1.0e-9`
`CO2_cy(time)`	`0.001564425`
`GAP(time)`	`1.0e-9`
`NAD(time)`	`0.000406654344`
`DHAP(time)`	`1.0e-9`
`LAC(time)`	`1.0e-9`
`MOPS(time)`	`0.0`
`MOPSH(time)`	`0.0`
`P2G(time)`	`1.0e-9`
`LAC_ec(time)`	`0.0`
`NADH(time)`	`4.06654344e-8`

virtualbacterialphotography — v0.0.1

Virtual Bacterial Photography

Details

viswanathan_shaw_rudy_1999 — v0.0.1

Viswanathan, Shaw, Rudy, 1999

Details

Parameters:

Name	Description
`nicholsarea`	`5.0e-5`
`preplength`	`0.001`
`gamma_Cai`	`1.0`
`gamma_Cao`	`0.341`
`hATP`	`2.0`
`stim_start`	`100.0`
`Tn_max`	`0.07`
`T`	`310.0`
`P_Na`	`6.75e-7`
`Km_Ca`	`0.0006`
`PNaK`	`0.01833`
`P_K`	`1.93e-7`
`K_mup`	`0.00092`
`G_rel_max`	`60000.0`
`d_NaCa`	`0.001`
`delta_Ca_ith`	`0.00018`
`Ko`	`4.5`
`gamma_Nao`	`0.75`
`Logicthresh`	`0.98`
`CMDN_max`	`0.05`
`delta_m`	`1.0e-5`
`tau_tr`	`0.18`
`Ca_NSR_max`	`15.0`
`kATP`	`0.00025`
`stim_duration`	`2.0`
`n_NaCa`	`3.0`
`Cao`	`1.8`
`g_Nab`	`0.004`
`K_mpCa`	`0.0005`
`gamma_Nai`	`0.75`
`stim_period`	`1000.0`
`stim_end`	`9.9999e7`
`K_mCSQN`	`0.8`
`K_mCMDN`	`0.00238`
`radius`	`0.00011`
`gamma_Ki`	`0.75`
`K_m_ns_Ca`	`0.0012`
`A_cap`	`1.434e-7`
`I_pCa`	`1.15`
`I_NaK`	`2.0`
`Nao`	`132.0`
`ATPi`	`3.0`
`K_mNai`	`10.0`
`P_Ca`	`0.00054`
`g_Na`	`16.0`
`I_up`	`5.0`
`g_Cab`	`0.003016`
`g_Kp`	`0.00552`
`stim_amplitude`	`-25.5`
`G_rel_overload`	`4000.0`
`K_mrel`	`0.0008`
`CSQN_max`	`10.0`
`gamma_Ko`	`0.75`
`g_CaT`	`0.05`
`K_mTn`	`0.0005`
`nATP`	`0.24`
`gamma`	`0.5`
`K_mKo`	`1.5`
`CSQNthresh`	`0.7`
`K_NaCa`	`0.002`
`F`	`96485.0`
`R`	`8314.0`

States:

Name	Description
`OVRLDtrack3(time)`	`2.2645e-282`
`xr(time)`	`0.0007500578`
`Ca_NSR(time)`	`2.7872629`
`OVRLDtrack2(time)`	`-2.5e-323`
`f(time)`	`0.995259`
`Cainfluxtrack(time)`	`1.660129e-87`
`APtrack2(time)`	`2.07066e-86`
`xs1(time)`	`0.0421517`
`j(time)`	`0.99511469`
`m(time)`	`0.0008601`
`xs2(time)`	`0.08866`
`Nai(time)`	`14.177596`
`APtrack3(time)`	`0.01924195`
`APtrack(time)`	`3.7458e-87`
`zdv(time)`	`0.01198974`
`d(time)`	`3.538268e-6`
`g(time)`	`0.9341828`
`OVRLDtrack(time)`	`2.0e-323`
`V(time)`	`-88.5004`
`h(time)`	`0.992806`
`ydv(time)`	`0.97497`
`Ca_JSR(time)`	`0.8204291`
`Ki(time)`	`138.37949`
`b(time)`	`0.0010301`
`Cai(time)`	`0.00034209`

VPH-MIP: VPH_MIP — v0.0.1

VPH-MIP case study on CellML

Details

Models used in the VPH-MIP standards and ontologies module for the CellML case study.

W

Walmsley_Rodriguez_2013 — v0.0.1

mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: A population-based simulation study

Details

mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: A population-based simulation study. This is an example of a model that uses parameter uncertainty, which is specified in terms of probability density functions.

wanant_quon_2000 — v0.0.1

Wanant, Quon, 2000

Details

Parameters:

Name	Description
`k1`	`1.0e6`
`k1_`	`0.0004`
`k5_`	`0.004`
`k4_`	`0.0004`
`k3`	`1.0e6`
`k4`	`1.0e6`
`k5`	`1.0e7`
`k3_`	`0.0004`
`k2`	`1.0e6`
`k2_`	`0.04`

States:

Name	Description
`x4(time)`	`1.0`
`x6(time)`	`1.0`
`x3(time)`	`1.0`
`x9(time)`	`1.0`
`x5(time)`	`1.0`
`x7(time)`	`1.0`
`x8(time)`	`1.0`
`x2(time)`	`0.1`
`x1(time)`	`10.0`

wang_cirit_haugh_2009 — v0.0.1

Wang, Cirit and Haugh 2009

Details

Parameters:

Name	Description
`Kph`	`4.64`
`kd_x2`	`2.85`
`Vmax_x12_KM_x12`	`4.71`
`KDL`	`1.5`
`L`	`1.0`
`KM_x21`	`21.6`
`Vmax_zph2_KM_zph2`	`0.228`
`KM_zph2`	`31.5`
`kd_w`	`0.0333`
`Vmax_y2_KM_y2`	`31.9`
`K_GR`	`495.0`
`KM_yph2`	`12.7`
`ke`	`0.2`
`Vmax_y1_KM_y1`	`11.8`
`kappa_PI3K`	`0.3`
`K_GP`	`5.09`
`Vmax_x21_KM_x21`	`0.405`
`k_FB_f`	`0.976`
`k_minusx`	`0.07`
`kd_x1`	`0.745`
`k_FB_ph`	`2.34`
`Wph`	`0.385`
`kxR0`	`0.3`
`KM_zph1`	`14.0`
`K_x2`	`6.77`
`KM_y2`	`8.81`
`kt`	`0.005`
`Zf`	`0.272`
`KM_y1`	`31.9`
`k_Ras`	`1.0`
`Vmax_x11_KM_x11`	`1.18`
`Vmax_yph1_KM_yph1`	`4.4`
`Kf`	`3.76`
`alpha_PI3K`	`80.0`
`KM_x12`	`45.5`
`KM_x11`	`30.3`
`Vmax_zph1_KM_zph1`	`0.451`
`KM_x22`	`15.7`
`gamma`	`0.1`
`KM_yph1`	`44.0`
`Vmax_yph2_KM_yph2`	`6.77`
`k_3PI`	`1.0`
`Vmax_x22_KM_x22`	`2.41`
`p`	`1.98`
`n`	`1.03`

States:

Name	Description
`e_ph(time)`	`1.0`
`zpp(time)`	`0.0`
`x2(time)`	`0.0`
`m_3PI(time)`	`0.0`
`y(time)`	`1.0`
`m_Ras(time)`	`0.0`
`z(time)`	`1.0`
`f_GEF(time)`	`1.0`
`c2(time)`	`0.0`
`r(time)`	`0.5`
`ypp(time)`	`0.0`
`w(time)`	`0.0`
`x1(time)`	`0.0`

wang_huang_huang_2006 — v0.0.1

Wang, Huang, Huang, 2006

Details

A quantitative kinetic model for ATP-induced intracellular Ca2+ oscillations.

Parameters:

Name	Description
`n`	`4.0`
`K_C2`	`2.0`
`k_5`	`0.12`
`k_4`	`1.2`
`K_D`	`0.01`
`K_S`	`0.025`
`k_0`	`0.0001`
`k_2`	`4.0`
`lambda`	`0.001`
`k_8`	`10.5`
`w`	`3.0`
`C_PLC_T`	`0.01`
`K_P`	`0.004`
`k_3`	`4.5`
`k_11`	`0.26`
`beta`	`0.05`
`rho`	`0.2`
`k_7`	`2.0`
`K_C1`	`1.0`
`k_10`	`3.0`
`m`	`2.0`
`K_G`	`0.025`
`K_R`	`0.2`
`k_6`	`14.0`
`k_9`	`0.6`
`K_ER`	`0.075`
`k_1`	`3.4`

States:

Name	Description
`G(time)`	`0.001`
`C_cyt(time)`	`0.2`
`C_ER(time)`	`1.0`
`IP_3(time)`	`0.001`
`APLC(time)`	`0.001`

wang_li_kuang_2007 — v0.0.1

Wang, Li, Kuang, 2007

Details

Parameters:

Name	Description
`C3`	`1000.0`
`alpha`	`0.29`
`Ub`	`72.0`
`C4`	`80.0`
`di`	`0.0107`
`Um`	`940.0`
`beta`	`1.77`
`C2`	`144.0`
`ti`	`100.0`
`U0`	`40.0`
`Vp`	`3.0`
`C5`	`26.0`
`Vg`	`10.0`
`Rg`	`180.0`
`Vi`	`11.0`

States:

Name	Description
`G(time)`	`150.0`
`I(time)`	`5.0`

wang_lin_lin_wu_2008 — v0.0.1

Wang, Lin, Lin, Wu, 2008

Details

Parameters:

Name	Description
`b_bar`	`0.28`
`C_m`	`0.009`
`I_mag`	`2.0`
`g_KCa`	`0.5`
`E_K`	`-70.0`
`V_beta_n`	`40.0`
`E_m`	`-42.0`
`k_2`	`0.011`
`V_alpha_m`	`10.0`
`beta_h_max`	`3.382`
`d_2`	`1.0`
`a_bar`	`0.48`
`kd`	`0.18`
`g_K`	`0.415`
`alpha_n_max`	`0.0229`
`k_pmca`	`0.2`
`E_Na`	`50.0`
`RT`	`2577.0`
`g_Ca0`	`0.05`
`V_beta_m`	`18.0`
`E_h`	`-41.0`
`E_Ca`	`50.0`
`f_cyt`	`0.01`
`k_serca`	`0.4`
`f_er`	`0.01`
`V_beta_h`	`7.6`
`alpha_h_max`	`0.0156`
`alpha_m_max`	`0.208`
`t_1`	`6.0`
`E_L`	`-75.0`
`alpha`	`4.5e-6`
`g_Na`	`0.45`
`p_leak`	`0.0005`
`v_cytver`	`5.0`
`V_alpha_h`	`14.7`
`E_n`	`-40.0`
`beta_n_max`	`0.09616`
`R_s`	`15.0`
`C_t`	`0.04`
`d_1`	`0.84`
`beta_m_max`	`2.081`
`g_Lmax`	`0.0024`
`V_alpha_n`	`7.0`
`t_0`	`5.0`
`k_1`	`0.18`

States:

Name	Description
`d(time)`	`0.0`
`o(time)`	`0.15`
`h(time)`	`1.0`
`n(time)`	`0.0`
`m(time)`	`0.0`
`c(time)`	`0.15`
`cer(time)`	`200.0`
`V_m(time)`	`-75.0`
`V_T(time)`	`-70.0`

wang_sobie_2008 — v0.0.1

Wang, Sobie, 2008

Details

Parameters:

Name	Description
`Vss`	`3.0734e-8`
`Kpc_max`	`0.23324`
`Clo`	`132000.0`
`R`	`8.314`
`T`	`298.0`
`stim_start`	`20.0`
`E_CaT`	`50.0`
`Km_CSQN`	`800.0`
`Kpcb`	`0.0005`
`k_minus_htrpn`	`3.2e-5`
`Km_Nai`	`21000.0`
`k_plus_a`	`0.00608`
`kf`	`0.023761`
`Cli`	`30000.0`
`Km_Cl`	`4.0`
`Ko`	`5400.0`
`i_NaK_max`	`0.88`
`Cm`	`1.0`
`v3`	`0.09`
`Km_CMDN`	`0.238`
`g_Kto_f`	`0.1017`
`k_sat`	`0.1`
`K_mNa`	`87500.0`
`eta`	`0.35`
`LTRPN_tot`	`35.0`
`g_Ks`	`0.046`
`n_ClCa`	`3.0`
`i_CaL_max`	`7.0`
`tau_tr`	`20.0`
`g_Kr`	`1.17`
`g_K1`	`0.235`
`K_mCa`	`1380.0`
`Acap`	`1.541e-5`
`Km_pCa`	`0.5`
`k_minus_a`	`0.07125`
`stim_duration`	`0.5`
`k_minus_b`	`0.965`
`v1`	`0.45`
`i_pCa_max`	`0.2`
`Cao`	`1000.0`
`Vmyo`	`2.2826e-6`
`Km_up`	`0.5`
`g_Nab`	`0.0026`
`tau_xfer`	`8.0`
`Kpc_half`	`20.0`
`Km_Ko`	`1500.0`
`stim_period`	`2000.0`
`stim_end`	`500000.0`
`k_minus_ltrpn`	`0.0196`
`kb`	`0.036778`
`k_plus_b`	`0.00405`
`CSQN_tot`	`15000.0`
`CMDN_tot`	`25.0`
`E_CaL`	`63.0`
`Nao`	`140000.0`
`P_ClCa`	`2.74e-7`
`HTRPN_tot`	`70.0`
`g_Na`	`10.0`
`VJSR`	`1.2e-9`
`k_plus_c`	`0.009`
`g_Cab`	`0.00025`
`stim_amplitude`	`-80.0`
`VNSR`	`2.098e-7`
`m`	`3.0`
`g_Kss`	`0.015`
`v2`	`2.088e-5`
`k_minus_c`	`0.0008`
`g_CaT`	`0.055`
`g_CaL`	`0.19019`
`k_plus_ltrpn`	`0.0327`
`g_Kur`	`0.0048`
`k_NaCa`	`907.68`
`k_plus_htrpn`	`0.00237`
`F`	`96.5`
`n`	`4.0`

States:

Name	Description
`O_K(time)`	`0.0021`
`ato_f(time)`	`0.0032`
`P_C2(time)`	`0.1003`
`C2(time)`	`0.00016996`
`HTRPN_Ca(time)`	`66.0407`
`C3(time)`	`1.1754e-8`
`C_K2(time)`	`0.00083641`
`O(time)`	`4.4776e-12`
`I2(time)`	`6.4226e-8`
`j(time)`	`0.9744`
`P_RyR(time)`	`2.8603e-14`
`nKs(time)`	`0.0026`
`C4(time)`	`6.1239e-10`
`m(time)`	`0.0032`
`Nai(time)`	`21747.0`
`ito_f(time)`	`0.753`
`Cass(time)`	`0.1867`
`g(time)`	`0.902`
`V(time)`	`-80.6475`
`h(time)`	`0.9606`
`LTRPN_Ca(time)`	`8.922`
`CaJSR(time)`	`705.5417`
`C_K1(time)`	`0.0011`
`aur(time)`	`0.00052471`
`iur(time)`	`0.9866`
`P_O1(time)`	`0.0011`
`Ki(time)`	`136450.0`
`b(time)`	`0.0047`
`I_K(time)`	`0.00043522`
`CaNSR(time)`	`703.3063`
`I3(time)`	`6.5201e-7`
`Cai(time)`	`0.2049`
`P_O2(time)`	`2.9799e-8`
`aKss(time)`	`0.85`
`I1(time)`	`1.545e-9`

warashina_ogura_2004 — v0.0.1

Warashina, Ogura, 2004

Details

Parameters:

Name	Description
`tau_m`	`nothing`
`T`	`nothing`
`a1`	`nothing`
`E_l`	`nothing`
`L`	`nothing`
`diameter`	`nothing`
`n_SK`	`nothing`
`beta_k`	`nothing`
`E_K`	`nothing`
`tau_s`	`nothing`
`Vmax`	`nothing`
`DCa`	`nothing`
`g_l`	`nothing`
`E_rev`	`nothing`
`vol0`	`nothing`
`FCaDy`	`nothing`
`Cm`	`nothing`
`tau1`	`nothing`
`a3`	`nothing`
`D`	`nothing`
`Dyi2`	`nothing`
`k1b`	`nothing`
`vol_i`	`nothing`
`g_K`	`nothing`
`TBu`	`nothing`
`tau2`	`nothing`
`Ai2`	`nothing`
`Ca_rest`	`nothing`
`Cac`	`nothing`
`E_Na`	`nothing`
`b1`	`nothing`
`Cai`	`nothing`
`PCa`	`nothing`
`Fm`	`nothing`
`Nc`	`nothing`
`a2`	`nothing`
`Cao`	`nothing`
`Kex`	`nothing`
`Fr`	`nothing`
`Ff`	`nothing`
`k1d`	`nothing`
`k2b`	`nothing`
`TDy`	`nothing`
`g_SK`	`nothing`
`A`	`nothing`
`F0`	`nothing`
`k2d`	`nothing`
`g_Na`	`nothing`
`Fs`	`nothing`
`Dkd`	`nothing`
`tau_f`	`nothing`
`A0`	`nothing`
`Ddy`	`nothing`
`R`	`nothing`
`F`	`nothing`
`Ca1`	`nothing`

States:

Name	Description
`Dy(time)`	`nothing`
`V(time)`	`nothing`
`Ca0(time)`	`nothing`
`CaDy(time)`	`nothing`
`h(time)`	`nothing`
`Bu(time)`	`nothing`
`B(time)`	`nothing`
`G(time)`	`nothing`
`n(time)`	`nothing`
`m(time)`	`nothing`
`Cai(time)`	`nothing`
`CaBu(time)`	`nothing`

warren_tawhai_crampin_2009 — v0.0.1

Warren, Tawhai, Crampin, 2009

Details

Parameters:

Name	Description
`Ka`	`0.3722419`
`P_pm_2`	`28.0`
`R`	`8314.0`
`Kpm`	`0.6`
`Jer0`	`0.0035`
`T`	`310.0`
`Ca_ext`	`1300.0`
`K_rc`	`0.3`
`k2`	`0.5`
`V_ATP`	`0.001`
`beta_4`	`0.01`
`Kc`	`0.0571428`
`alpha_4`	`0.06`
`PIP2_Total`	`25.0`
`Beta_2`	`36.0`
`K_IP3`	`0.01`
`P_pm_1`	`0.6`
`V_mech0`	`1.0`
`Vm`	`-39.0`
`Kb`	`0.636005`
`z_Ca`	`2.0`
`k1_`	`0.88`
`Jryr0`	`0.0`
`Vpm`	`0.072`
`Beta_1`	`0.0`
`alpha_1`	`40.0`
`C_4`	`10.0`
`volume_i0`	`1450.0`
`Kserca`	`0.04`
`beta_1`	`0.8`
`K_ATP`	`0.0001`
`Jipt0`	`28.0`
`C_1`	`2.6`
`k3`	`0.5`
`J_ip3R0`	`10.0`
`Vserca`	`0.09`
`gamma`	`4.9`
`MechanicalStimulation`	`0.0`
`k5`	`0.02`
`C_2`	`0.02`
`F`	`96485.0`
`C_3`	`2.3`

States:

Name	Description
`volume_iIP3(time)`	`-3.28287434380887e-93`
`O(time)`	`-2.42013500345263e-89`
`I2(time)`	`1.01276768045278e-40`
`volumeCa_i(time)`	`75.8335890358239`
`PIP2(time)`	`1.0`
`volumeCa_er(time)`	`1199.73747802144`
`ATP_e(time)`	`0.0`
`I1(time)`	`2.24343309680416e-81`

waugh_sherratt_2006 — v0.0.1

Waugh, Sherratt, 2006

Details

Parameters:

Name	Description
`tau1`	`-2.47`
`d1`	`0.2`
`alpha`	`0.8`
`k1`	`0.05`
`tau3`	`6.41`
`tau4`	`1.75`
`tau2`	`21.94`
`k4`	`0.07`
`k3`	`0.002`
`k2`	`0.693`
`d2`	`9.1`

States:

Name	Description
`T(time)`	`6.0`
`phi_I(time)`	`200.0`
`phi_R(time)`	`200.0`

waugh_sherratt_2007 — v0.0.1

Waugh, Sherratt, 2007

Details

Parameters:

Name	Description
`k10`	`0.924`
`k9`	`0.0015`
`k8`	`0.015`
`tau4`	`0.2527`
`k4`	`0.07`
`d6`	`0.7`
`k6`	`0.0004`
`k11`	`5.0`
`tau1`	`0.0092`
`d2`	`9.1`
`d1`	`0.2`
`k12`	`0.001`
`tau3`	`0.6279`
`k1`	`0.05`
`d5`	`1.5e-5`
`d3`	`4.0`
`tau2`	`-0.1552`
`k3`	`0.002`
`k7`	`0.004`
`d4`	`2.5`
`k5`	`0.0025`
`k2`	`0.693`

States:

Name	Description
`P(time)`	`2.0`
`H(time)`	`0.01`
`T(time)`	`6.0`
`phi_I(time)`	`200.0`
`C(time)`	`10.0`
`F(time)`	`50.0`
`phi_R(time)`	`200.0`

webb_sherratt_fish_2002 — v0.0.1

Webb, Sherratt, Fish, 2002

Details

Parameters:

Name	Description
`k10`	`3110.0`
`k9`	`8.73e9`
`k1`	`8.38e-10`
`k8`	`1.92e10`
`k4`	`0.35`
`k3`	`5.9413`
`k7`	`0.35`
`k6`	`2244.0`
`k5`	`2.52e-9`
`k2`	`0.006`
`k11`	`13.9`

States:

Name	Description
`SL(time)`	`0.0`
`T(time)`	`500.0`
`m(time)`	`500.0`
`LT(time)`	`0.0`
`Lm(time)`	`1000.0`
`Rm(time)`	`1000.0`
`RT(time)`	`10000.0`

wein_damato_perelson_1998 — v0.0.1

Wein, D'Amato, Perelson 1998

Details

Parameters:

Name	Description
`c1`	`3.07`
`N1`	`480.1`
`delta2_M`	`0.062`
`m21`	`3.4e-5`
`mu`	`0.0014`
`Tmax`	`450.0`
`N2`	`475.3`
`lambda`	`0.01`
`s`	`0.0`
`c2`	`3.07`
`delta1_M`	`0.062`
`m12`	`3.4e-5`
`m11`	`1.0`
`k1`	`3.43e-8`
`delta1`	`0.69`
`r1`	`0.9`
`r2`	`0.25`
`N1_M`	`534.4`
`k2_M`	`4.67e-9`
`N2_M`	`529.0`
`p2`	`0.25`
`delta2`	`0.69`
`lambda_M`	`2.0`
`mu_M`	`0.04`
`p1`	`0.99`
`m22`	`1.0`
`k2`	`3.43e-8`
`k1_M`	`4.67e-9`

States:

Name	Description
`T1_star(time)`	`1.19`
`M1_star(time)`	`0.49`
`V2(time)`	`450.0`
`M(time)`	`49.2`
`V1(time)`	`133500.0`
`T(time)`	`178.81`
`M2_star(time)`	`0.0017`
`V2_I(time)`	`450.0`
`V1_I(time)`	`133500.0`
`T2_star(time)`	`0.004`

weinstein_1998 — v0.0.1

Weinstein, 1998

Details

Parameters:

Name	Description
`k7b`	`2.6e10`
`P`	`5.0`
`k9`	`1.75`
`k6a`	`5.0e7`
`k8`	`54.0`
`k3a`	`5.3e9`
`k6_`	`5.0e10`
`k10_`	`50.0`
`k1_`	`6.5`
`k5_`	`200.0`
`k6b`	`5.0e7`
`k4_`	`2.5e6`
`k3b_`	`660.0`
`k6a_`	`8.0e12`
`k3`	`1.3e9`
`ADP`	`0.04`
`k3b`	`5.3e9`
`K`	`20.0`
`k7b_`	`1.5e8`
`k3a_`	`660.0`
`ATP`	`2.0`
`k10`	`50000.0`
`k7_`	`3.4e7`
`k7a`	`2.6e10`
`k2b_`	`73000.0`
`k2b`	`8900.0`
`k9_`	`35.0`
`k2a`	`8900.0`
`k4`	`50.0`
`k8_`	`32.0`
`k6b_`	`8.0e12`
`k6`	`5.0e7`
`k7a_`	`1.5e8`
`H`	`4.0`
`k11`	`500.0`
`k11_`	`5.0`
`k1`	`1.3e7`
`k3_`	`500.0`
`k2_`	`40000.0`
`k2a_`	`73000.0`
`k7`	`2.0e10`
`k5`	`40.0`
`k2`	`4000.0`

States:

Name	Description
`K2_E2(time)`	`nothing`
`H2_E1_ATP(time)`	`nothing`
`K2_E1(time)`	`nothing`
`H2_E2_P(time)`	`nothing`
`K_E2_P(time)`	`nothing`
`H2_E1_P(time)`	`nothing`
`H_E1_P(time)`	`nothing`
`H_E2_P(time)`	`nothing`
`H_E1_ATP(time)`	`nothing`
`K_E2_ATP(time)`	`nothing`
`K_E1(time)`	`nothing`
`K2_E2_P(time)`	`nothing`
`K2_E2_ATP(time)`	`nothing`
`E2_P(time)`	`nothing`
`E1_ATP(time)`	`nothing`
`K_E2(time)`	`nothing`
`K_E1_ATP(time)`	`nothing`
`K2_E1_ATP(time)`	`nothing`

weinstein_2000 — v0.0.1

Weinstein 2000

Details

A mathematical model of the outer medullary collecting duct of the rat

Parameters:

Name	Description
`Pc_pp`	`61.0`
`Cl_i`	`29.0`
`K_I`	`172.0`
`Kc_p`	`50.0`
`Kb_p`	`198.0`
`Kc_pp`	`50.0`
`Cl_e`	`114.0`
`Kb_pp`	`198.0`
`Pb_p`	`1247.0`
`HCO3_e`	`26.0`
`Pb_pp`	`135.0`
`x_Tmax`	`1.0`
`Pc_p`	`562.0`

States:

Name	Description
`HCO3_i(time)`	`0.0`

westermark_lansner_2003 — v0.0.1

Westermark, Lansner, 2003

Details

Parameters:

Name	Description
`Pfba`	`0.5`
`dw_per_ml`	`0.3333`
`G6P_F6P_init`	`3.71728`
`Sgk`	`8.0`
`Spfk`	`4.0`
`Sfba`	`0.005`
`a`	`1.0`
`one`	`1.0`
`Sgapdh`	`0.005`
`Keq_FBA`	`0.1`
`h_PFK`	`2.5`
`Keq`	`0.045455`
`V_GK_min`	`10.0`
`hx`	`2.5`
`FBP_init`	`0.00063612`
`alpha`	`5.0`
`Qfba`	`0.275`
`min_to_sec`	`60.0`
`h_GK`	`1.7`
`V_PFK_min`	`100.0`
`V_min`	`25.0`
`V_GAPDH_min`	`250.0`
`Y_init`	`0.00063612`
`h_act`	`1.0`
`Keq_TPI`	`0.045455`
`Keq_GPI`	`0.3`
`two`	`2.0`
`Xpfk`	`0.01`
`DHAP_G3P_init`	`0.00262966`
`V_FBA_min`	`25.0`

States:

Name	Description
`DHAP_G3P(time)`	`0.00262966`
`Y(time)`	`0.00063612`
`FBP(time)`	`0.00063612`
`G6P_F6P(time)`	`3.71728`

wierschem_bertram_2004 — v0.0.1

Wierschem 2004

Details

Parameters:

Name	Description
`v`	`10.0`
`f`	`0.001`
`s_m`	`12.0`
`C_m`	`5300.0`
`g_K_`	`3000.0`
`tau_n`	`16.0`
`k`	`20.0`
`alpha`	`2.25e-6`
`v_n`	`-16.0`
`k_D`	`0.3`
`eta`	`185.0`
`V_K`	`-75.0`
`g_KATP_`	`350.0`
`V_Ca`	`25.0`
`tau_c`	`1200.0`
`k_c`	`0.1`
`g_KCa_`	`300.0`
`g_Ca_`	`1200.0`
`v_m`	`-20.0`
`s_n`	`5.6`

States:

Name	Description
`V(time)`	`-67.018`
`n(time)`	`0.00011`
`c(time)`	`0.15666`
`ATP(time)`	`2.1047`
`ADP(time)`	`0.085817`

wilkins_sneyd_1998 — v0.0.1

Wilkins, Sneyd, 1998

Details

Parameters:

Name	Description
`dc_dy2`	`nothing`
`Dc`	`nothing`
`tau_h`	`nothing`
`c`	`nothing`
`dc_dx2`	`nothing`
`b`	`nothing`
`k1`	`nothing`
`kf`	`nothing`
`k_mu`	`nothing`
`gamma`	`nothing`
`k_gamma`	`nothing`
`k2`	`nothing`
`p`	`nothing`

States:

Name	Description
`h(time)`	`nothing`
`mu_p(time)`	`nothing`

winograd_destexhe_sanchezvives_2008 — v0.0.1

Winograd, Destexhe, Sanchezvives, 2008

Details

Parameters:

Name	Description
`Z`	`2.0`
`tau_m`	`0.02`
`V_T`	`-55.0`
`T`	`296.65`
`i_stimAmplitude`	`-0.3`
`E_h`	`-20.0`
`C_m`	`0.001`
`tau_r`	`0.017`
`k_4`	`1.0`
`Ca_o`	`2.0`
`n_Ca`	`4.0`
`cac`	`0.006`
`E_K`	`-95.0`
`g_KD`	`7.0`
`i_stimStart`	`5.0`
`period`	`9.0`
`k_2`	`0.1`
`P_c`	`0.01`
`Ca_inf`	`0.0001`
`g_inc`	`2.0`
`d`	`0.0001`
`V_S`	`0.0`
`Ca_c`	`0.006`
`P_Ca`	`0.000276`
`g_Na`	`70.0`
`k`	`0.1`
`E_leak`	`-70.0`
`n_exp`	`1.0`
`p_C`	`0.01`
`tau_max`	`4.0`
`g_hbar`	`0.02`
`i_stimEnd`	`9.0`
`g_KM`	`0.004`
`g_leak`	`1.0`
`E_Na`	`50.0`
`R`	`8.314`
`F`	`96489.0`

States:

Name	Description
`p_1(time)`	`nothing`
`p(time)`	`nothing`
`V(time)`	`nothing`
`h(time)`	`nothing`
`m(time)`	`nothing`
`n(time)`	`nothing`
`Ca_i(time)`	`nothing`
`q(time)`	`nothing`
`o_2(time)`	`nothing`

winslow_rice_jafri_marban_ororke_1999 — v0.0.1

Winslow, Rice, Jafri, Marban, Ororke, 1999

Details

Parameters:

Name	Description
`f`	`300.0`
`k_a_minus`	`576.0`
`K_mEGTA`	`0.00015`
`stim_start`	`0.1`
`T`	`310.0`
`C_sc`	`0.001`
`K_SR`	`1.0`
`i_Ca_half`	`-0.265`
`Vmaxr`	`0.318`
`k_htrpn_plus`	`20000.0`
`K_sat`	`0.2`
`omega`	`10.0`
`K_mK1`	`13.0`
`k_b_minus`	`1930.0`
`Ko`	`4.0`
`k_htrpn_minus`	`0.066`
`V_NSR`	`2.1e-6`
`g`	`2000.0`
`K_mNa`	`87.5`
`eta`	`0.35`
`LTRPN_tot`	`0.07`
`k_b_plus`	`4.05e9`
`g_Ks`	`0.0027134`
`k_c_plus`	`100.0`
`g_K1`	`2.8`
`tau_tr`	`0.0005747`
`g_Kr`	`0.0034`
`V_myo`	`2.584e-5`
`K_mCa`	`1.38`
`k_c_minus`	`0.8`
`EGTA_tot`	`0.0`
`k_a_plus`	`1.215e13`
`stim_duration`	`0.002`
`fprime`	`7.0`
`v1`	`1800.0`
`b`	`2.0`
`Cao`	`2.0`
`V_SS`	`1.2e-9`
`g_Nab`	`0.0031`
`tau_xfer`	`0.0267`
`K_mpCa`	`5.0e-5`
`a`	`2.0`
`tau_factor`	`1.0`
`stim_period`	`1.0`
`stim_end`	`1.0e8`
`V_JSR`	`1.6e-7`
`K_mCSQN`	`0.8`
`K_mCMDN`	`0.00238`
`K_fb`	`0.000168`
`gprime`	`7000.0`
`A_cap`	`0.0001534`
`k_ltrpn_minus`	`40.0`
`I_pCa`	`0.05`
`I_NaK`	`0.693`
`CSQN_tot`	`15.0`
`k_ltrpn_plus`	`40000.0`
`Nao`	`138.0`
`CMDN_tot`	`0.05`
`K_mNai`	`10.0`
`N_rb`	`1.0`
`N_fb`	`1.2`
`HTRPN_tot`	`0.14`
`g_to1`	`0.23815`
`P_Ca`	`0.0003125`
`g_Na`	`12.8`
`Vmaxf`	`0.0813`
`g_Cab`	`0.0003842`
`g_Kp`	`0.002216`
`stim_amplitude`	`-21.1268`
`K_rb`	`3.29`
`m`	`3.0`
`K_NaCa`	`0.3`
`K_mKo`	`1.5`
`R`	`8.314472`
`P_K`	`5.79e-7`
`F`	`96.4853415`
`n`	`4.0`

States:

Name	Description
`X_kr(time)`	`0.51`
`P_C1(time)`	`0.47`
`Ca_ss(time)`	`0.00011`
`Ca_NSR(time)`	`0.257`
`P_C2(time)`	`0.53`
`C0(time)`	`0.997208`
`y(time)`	`0.798`
`C2(time)`	`1.535e-9`
`C3(time)`	`1.63909e-14`
`HTRPNCa(time)`	`0.98`
`O(time)`	`9.84546e-21`
`j(time)`	`0.99254`
`C_Ca0(time)`	`0.00272826`
`C_Ca3(time)`	`2.87031e-15`
`m(time)`	`0.0328302`
`X_to1(time)`	`2.63`
`C4(time)`	`6.56337e-20`
`Y_to1(time)`	`0.99`
`Nai(time)`	`10.0`
`LTRPNCa(time)`	`0.078`
`X_ks(time)`	`0.264`
`C_Ca4(time)`	`4.59752e-20`
`V(time)`	`-96.1638`
`h(time)`	`0.988354`
`C_Ca1(time)`	`6.99215e-7`
`C1(time)`	`6.38897e-5`
`P_O1(time)`	`0.0`
`Ki(time)`	`157.8`
`Ca_JSR(time)`	`0.257`
`O_Ca(time)`	`0.0`
`Cai(time)`	`8.0e-5`
`P_O2(time)`	`0.0`
`C_Ca2(time)`	`6.71989e-11`

wodarz_2003 — v0.0.1

Wodarz, 2003

Details

Parameters:

Name	Description
`k_1`	`1.0`
`g`	`0.01`
`a_1`	`0.03`
`alpha_1`	`0.1`
`r`	`0.5`
`a_2`	`1.0`
`beta_2`	`1.0`
`beta_1`	`1.0`
`alpha_2`	`0.1`
`epsilon`	`0.1`
`k_2`	`1.0`
`u`	`0.5`
`d`	`0.01`

States:

Name	Description
`P_2(time)`	`1.0`
`I_2(time)`	`0.0`
`I_21(time)`	`0.0`
`R_1(time)`	`0.0`
`P_1(time)`	`1.0`
`S(time)`	`100.0`
`I_1(time)`	`0.0`
`R_2(time)`	`0.0`
`I_12(time)`	`0.0`
`R_12(time)`	`0.0`

wodarz_hamer_2007 — v0.0.1

Wodarz, Hamer, 2007

Details

Parameters:

Name	Description
`c`	`1.0`
`k`	`10.0`
`alpha`	`0.2`
`b`	`0.1`
`r`	`1.0`
`eta`	`1.0`
`a`	`0.2`
`delta`	`0.01`
`rho`	`0.3`
`beta`	`0.3`
`epsilon`	`1.0`
`phi`	`1.5`
`lambda`	`1.0`
`xi`	`0.01`
`gamma`	`0.01`
`u`	`1.0`
`p`	`45.0`
`d`	`0.001`

States:

Name	Description
`m_7(time)`	`0.0`
`m_4(time)`	`0.0`
`m_3(time)`	`0.0`
`T(time)`	`1000.0`
`I(time)`	`0.0001`
`v(time)`	`0.0001`
`x(time)`	`10.0`
`y(time)`	`0.0`
`z(time)`	`0.0`
`m_9(time)`	`0.0`
`m_0(time)`	`0.1`
`m_5(time)`	`0.0`
`m_8(time)`	`0.0`
`m_1(time)`	`0.0`
`m_6(time)`	`0.0`
`m_2(time)`	`0.0`
`w(time)`	`0.0`

wodarz_jansen_2003 — v0.0.1

Wodarz, Jansen, 2003

Details

Parameters:

Name	Description
`delta_1`	`0.1`
`k`	`10.0`
`alpha`	`0.05`
`r`	`0.5`
`eta`	`2.0`
`mu`	`0.1`
`delta_2`	`1.5`
`epsilon`	`1.0`
`gamma`	`1.0`
`lambda`	`1.0`
`q`	`0.5`
`d`	`0.1`

States:

Name	Description
`A(time)`	`1.0`
`T(time)`	`0.1`
`C(time)`	`0.015`
`A_star(time)`	`2.0`

wodarz_nowak_1999 — v0.0.1

Wodarz, Nowak, 1999

Details

Parameters:

Name	Description
`p`	`1.0`
`d`	`0.1`
`c`	`0.1`
`b`	`0.01`
`lamda`	`1.0`
`q`	`0.5`
`a`	`0.2`
`h`	`0.1`
`beta`	`0.5`

States:

Name	Description
`x(time)`	`10.0`
`y(time)`	`0.1`
`w(time)`	`0.001`
`z(time)`	`0.0`

wodarz_sierro_klenerman_2007 — v0.0.1

Wodarz, Sierro, Klenerman, 2007

Details

Parameters:

Name	Description
`pa`	`1.0e-6`
`a0`	`0.1`
`k`	`1.0`
`a1`	`0.2`
`alpha`	`0.2`
`r`	`1.0`
`eta`	`0.01`
`ba`	`0.1`
`beta`	`0.1`
`ci`	`12.0`
`bi`	`0.1`
`phi`	`0.1`
`lambda`	`10.0`
`xi`	`0.01`
`ca`	`15.5`
`gamma`	`0.5`
`p_i`	`1.0`
`u`	`1.0`
`d`	`0.1`

States:

Name	Description
`m_7(time)`	`0.0`
`m_4(time)`	`0.0`
`m_3(time)`	`0.0`
`v(time)`	`1.0`
`x(time)`	`1.0`
`y1(time)`	`0.0`
`L(time)`	`0.0`
`m_0(time)`	`0.0`
`m_5(time)`	`0.0`
`m_8(time)`	`0.0`
`m_1(time)`	`0.0`
`za(time)`	`1.0`
`m_6(time)`	`0.0`
`m_2(time)`	`0.0`
`zi(time)`	`0.1`
`y0(time)`	`0.0`

wolf_heinrich_2000 — v0.0.1

Wolf, Heinrich, 2000

Details

Parameters:

Name	Description
`A`	`4.0`
`K_I`	`0.52`
`Jo`	`3.0`
`k`	`1.3`
`k_5`	`1.28`
`k_4`	`100.0`
`k_3`	`16.0`
`N`	`1.0`
`kappa`	`13.0`
`k_2`	`6.0`
`phi`	`0.1`
`k_6`	`12.0`
`q`	`4.0`
`k_1`	`100.0`

States:

Name	Description
`S3(time)`	`0.2`
`S4_ex(time)`	`0.1`
`S1(time)`	`5.8`
`A3(time)`	`2.4`
`N2(time)`	`0.1`
`S2(time)`	`0.9`
`S4(time)`	`0.2`

wolf_passarge_somsen_snoep_heinrich_westerhoff_2000 — v0.0.1

Wolf, Passarge, Somsen, Snoep, Heinrich, Westerhoff, 2000

Details

Parameters:

Name	Description
`k_1`	`550.0`
`k_PGK_plus`	`76411.1`
`K_i`	`1.0`
`A`	`4.0`
`Jo`	`50.0`
`k_8`	`85.7`
`k_GAPDH_minus`	`57823.1`
`k_5`	`9.7`
`k_4`	`80.0`
`k`	`375.0`
`k_7`	`28.0`
`k_PGK_minus`	`23.7`
`k_GAPDH_plus`	`323.8`
`N`	`1.0`
`k_2`	`9.8`
`phi`	`0.1`
`k_6`	`2000.0`
`k_9`	`80.0`
`n`	`4.0`

States:

Name	Description
`S6(time)`	`0.078042624`
`S6_ex(time)`	`0.025277594`
`S3(time)`	`0.468657507`
`S5(time)`	`8.210114438`
`S1(time)`	`1.57981839`
`A3(time)`	`1.972814237`
`N2(time)`	`0.384873894`
`S4(time)`	`0.589391932`
`S2(time)`	`4.8279999`

wolf_sohn_heinrich_kuriyama_2001 — v0.0.1

Wolf, Sohn, Heinrich, Kuriyama, 2001

Details

Parameters:

Name	Description
`k14`	`10.0`
`Kc`	`0.1`
`KA`	`1.0`
`v0`	`1.6`
`k18`	`1.0`
`k9`	`10.0`
`KH`	`0.5`
`k15`	`5.0`
`A_m`	`2.0`
`k8`	`10.0`
`k4`	`0.2`
`N`	`2.0`
`k6`	`0.12`
`v10`	`80.0`
`k11`	`10.0`
`v13`	`4.0`
`k12`	`5.0`
`alpha`	`0.1`
`k16`	`10.0`
`A_c`	`2.0`
`S`	`2.0`
`m`	`4.0`
`k3`	`0.2`
`k7`	`10.0`
`k17`	`0.02`
`k5`	`0.1`
`k2`	`0.2`
`n`	`4.0`

States:

Name	Description
`sul(time)`	`0.012871557`
`aps(time)`	`0.053366179`
`hyd(time)`	`0.159317029`
`A3_c(time)`	`1.570847601`
`eth(time)`	`10.25246999`
`oah(time)`	`5.571685096`
`aco(time)`	`1.139360412`
`A3_m(time)`	`1.835158493`
`oxy(time)`	`6.146549084`
`pap(time)`	`0.082791522`
`cys(time)`	`0.805117739`
`S1(time)`	`1.892468811`
`N2(time)`	`1.933616149`

wu_jeneson_beard_2006 — v0.0.1

Wu, Jeneson, Beard, 2006

Details

Parameters:

Name	Description
`X_PI2`	`327.0`
`k_PIH`	`0.0002542`
`mincond`	`1.0e-6`
`r`	`4.559`
`V_mito`	`0.056`
`dG_C4o`	`-122.94`
`dG_F1o`	`36.03`
`n_A`	`3.0`
`k_mADP`	`3.5e-6`
`mincon`	`1.0e-9`
`X_CK`	`1.0e7`
`k_PI2`	`0.0008222`
`X_AK`	`1.0e7`
`X_F1`	`1000.0`
`k_PI3`	`0.0003601`
`X_Hle`	`200.0`
`O2_x`	`3.48e-5`
`k_PI4`	`0.005651`
`X_MgA`	`1.0e7`
`X_KH`	`5.651e7`
`NAD_tot`	`0.00297`
`k_PI1`	`0.0001553`
`X_AtC`	`0.0`
`RT`	`2.5775`
`K_c`	`0.15`
`X_C1`	`4405.0`
`K_AK`	`0.4331`
`C_IM`	`6.75e-6`
`k_O2`	`0.00012`
`X_C3`	`4.887`
`V_cyto`	`0.894`
`Q_tot`	`0.00135`
`K_DT`	`2.4e-5`
`x_buff`	`100.0`
`C_tot`	`0.0027`
`X_A`	`85.0`
`dG_C3o`	`-32.53`
`dG_C1o`	`-69.37`
`pH_C`	`7.0`
`X_K`	`0.0`
`X_ANT`	`0.008123`
`X_C4`	`6.766e-5`
`K_DD`	`0.000347`
`gamma`	`5.99`
`X_DH`	`0.0866`
`X_PI1`	`385000.0`
`CR_tot`	`0.0427`
`K_CK`	`1.66e9`
`F`	`0.096484`

States:

Name	Description
`NADH_x(time)`	`0.0015723`
`ATP_mc(time)`	`0.0079786`
`ADP_mc(time)`	`5.1958e-5`
`Mg_x(time)`	`0.0010229`
`K_x(time)`	`0.14661`
`Q_x(time)`	`0.000675`
`Mg_c(time)`	`0.001003`
`pH_x(time)`	`7.0`
`PI_i(time)`	`0.000172`
`ADP_i(time)`	`6.5773e-5`
`ADP_c(time)`	`6.85e-5`
`ADP_mi(time)`	`4.8866e-5`
`Cox_x(time)`	`0.00135`
`ADP_mx(time)`	`0.0054765`
`Mg_i(time)`	`0.0010029`
`PI_x(time)`	`0.000172`
`ADP_x(time)`	`0.0073343`
`AMP_c(time)`	`3.0911e-7`
`ATP_i(time)`	`0.0065339`
`AMP_i(time)`	`2.8837e-7`
`ATP_mi(time)`	`0.0063812`
`ATP_x(time)`	`0.0026657`
`ATP_mx(time)`	`0.0026046`
`ATP_c(time)`	`0.0081312`
`PCr_c(time)`	`0.023589`
`PI_c(time)`	`0.0087702`
`deltaPsi(time)`	`166.67`

wu_yang_vinnakota_beard_2007 — v0.0.1

Wu, Yang, Vinnakota, Beard, 2007

Details

Parameters:

Name	Description
`X_mdh`	`0.077060004692409`
`dGf1_O2`	`16.4`
`KMg_COASH_x`	`1.0e20`
`dGf1_ATP`	`-2771.0`
`dFADH2_x_dt`	`0.0`
`K_aADP`	`0.0001`
`K_mMAL`	`0.0001977`
`K_iSCOA`	`0.00014`
`KK_NAD_x`	`1.0e20`
`dGf1_COQ`	`65.17`
`rho_m`	`272500.0`
`KMg_QH2_x`	`1.0e20`
`J_AtC`	`0.0`
`KH_K_x`	`1.0e20`
`X_KH`	`4.758023126099895e6`
`K_mMALi`	`0.0014`
`K_ir_akgd`	`6.04e-7`
`dGf1_Cox`	`-6.52`
`KK_NADH_x`	`1.0e20`
`dGf1_Cred`	`-27.41`
`KK_K_x`	`1.0e20`
`K_iAMP`	`0.00065`
`KK_ASP_x`	`1.0e20`
`dGf1_QH2`	`-23.3`
`n_H`	`3.0`
`KH_COQ_x`	`1.0e20`
`K_mB`	`5.5e-5`
`KK_FADH2_x`	`1.0e20`
`dGf1_ACCOA`	`-178.19`
`k_PIHt`	`0.00161251709168`
`dGf1_GLU`	`-692.4`
`dGf1_GLC`	`-907.21`
`K_mP`	`4.7e-5`
`K_iNADH`	`4.0e-5`
`W_x`	`0.651384`
`K_mSUC`	`0.000467`
`dGf1_FUM`	`-603.32`
`K_iASPi`	`2.8e-5`
`X_pdh`	`0.205093643103884`
`X_GLUH`	`2.725114215177993e8`
`X_CITMAL`	`80.43211032286638`
`X_PIHt`	`3.335568500871044e7`
`K_mFUM`	`0.0012`
`X_akgd`	`0.087630003425524`
`KH_ACCOA_x`	`1.0e20`
`F`	`0.096484`
`dGf1_PYR`	`-470.82`
`KMg_NADH_x`	`1.0e20`
`zero`	`0.0`
`K_ir`	`1.11e-5`
`KK_Mg_x`	`1.0e20`
`Ki_G6P`	`1.0e-5`
`dGf1_CIT`	`-1165.59`
`KH_PYR_x`	`1.0e20`
`theta`	`0.6`
`X_isod`	`0.492047553306503`
`KMg_FADH2_x`	`1.0e20`
`cytC_tot`	`0.0027`
`X_Hle`	`302.092849850504`
`dGf1_NAD`	`18.1`
`X_PiHt`	`3.335568500871044e7`
`K_Mg`	`1.0e20`
`KK_GLU_x`	`1.0e20`
`dGf1_ADP`	`-1903.96`
`KMg_COQ_x`	`1.0e20`
`KH_FADH2_x`	`1.0e20`
`CO2_tot_x`	`0.0214`
`dAMP_x_dt`	`0.0`
`KMg_FAD_x`	`1.0e20`
`K_mNAD`	`9.055e-5`
`NAD_tot`	`0.00297`
`KH_QH2_x`	`1.0e20`
`minCon`	`1.0e-32`
`dGf1_FAD`	`19.55`
`K_mQH2`	`2.45e-6`
`V_mf`	`0.087630003425524`
`A_tot`	`0.01`
`dGf1_GDP`	`-1903.96`
`dGf1_Pi`	`-1098.27`
`X_C1`	`32364.81869934019`
`KMg_H_x`	`1.0e20`
`KH_H_x`	`1.0e20`
`X_C3`	`0.790813746051711`
`B_x`	`0.02`
`dGf1_GTP`	`-2771.0`
`KMg_CO2_tot_x`	`1.0e20`
`KMg_AKG_x`	`1.0e20`
`X_ndk`	`0.025543515147654`
`X_SUCMAL`	`96.99561824738987`
`KK_PYR_x`	`1.0e20`
`K_mMALx`	`0.0007`
`K_ic`	`0.002`
`KK_COQ_x`	`1.0e20`
`X_sdh`	`0.08578867843174`
`K_aFUM`	`0.000375`
`KK_QH2_x`	`1.0e20`
`KK_AKG_x`	`1.0e20`
`k_PiHt`	`0.00161251709168`
`X_C4`	`0.0001076088893810943`
`X_MALPI`	`16.062441848715917`
`K_iATP`	`5.0e-5`
`KK_ACCOA_x`	`1.0e20`
`KK_O2_x`	`1.0e20`
`k_PI_2`	`0.003474542589709`
`X_scoas`	`0.448520452008943`
`p_TI`	`85.0`
`StateType`	`2.0`
`p_PI`	`327.0`
`dGf1_AKG`	`-793.41`
`K_mR`	`1.11e-5`
`n_A`	`3.0`
`K_iCIT`	`0.0035`
`KK_OAA_x`	`1.0e20`
`KH_NAD_x`	`1.0e20`
`k_mADP`	`3.5e-6`
`X_CK`	`1.0e7`
`W_i`	`0.072376`
`FAD_tot`	`0.0001`
`KK_FUM_x`	`1.0e20`
`X_AK`	`1.0e7`
`KH_AKG_x`	`1.0e20`
`dGf1_SCOA`	`-507.55`
`K_H`	`1.0e20`
`p_A`	`85.0`
`dGf1_OAA`	`-794.74`
`KH_Mg_x`	`1.0e20`
`X_ASPGLU`	`5.865621634754698e-5`
`K_ib`	`4.7e-5`
`K_iGDP`	`0.00033`
`K_iAKG`	`0.0166`
`KH_NADH_x`	`1.0e20`
`KMg_FUM_x`	`1.0e20`
`X_acon`	`0.027665411180519`
`X_got`	`4.551391837332316`
`pKa_ASPGLU`	`6.5`
`dGf1_ASP`	`-692.26`
`k_PI_1`	`3.248913595933763e-5`
`X_cits`	`9.82530750761898`
`K_mAKGi`	`0.0003`
`K_mC`	`2.1e-5`
`K_mNADH`	`2.58e-6`
`k_O2`	`0.00012`
`K_iCOASH`	`6.7e-5`
`KMg_Mg_x`	`1.0e20`
`Q_tot`	`0.00135`
`K_ir1`	`6.010527470838273e-7`
`dGf1_Cr`	`-252.68`
`K_ia`	`0.001`
`X_ANT`	`0.007522124149343`
`m`	`1.8`
`dGf1_AMP`	`-1034.66`
`KK_ICIT_x`	`1.0e20`
`CR_tot`	`0.0427`
`K_BX`	`1.0e-7`
`K_mA`	`8.0e-5`
`K_mCOQ`	`0.00048`
`dGf1_H2O`	`-235.74`
`K_iGTP`	`8.0e-5`
`K_aSUC`	`0.00045`
`ExpType`	`1.0`
`K_iq`	`6.9e-6`
`K_iOAA`	`1.5e-6`
`dGf1_ICIT`	`-1158.94`
`X_F1`	`8120.393248498723`
`X_AKGMAL`	`0.282091450119444`
`KK_CO2_tot_x`	`1.0e20`
`KK_COASH_x`	`1.0e20`
`dGf1_NADH`	`39.31`
`dCO2_tot_x_dt`	`0.0`
`K_mAKGx`	`0.00017`
`dGf1_SUC`	`-690.44`
`KMg_O2_x`	`1.0e20`
`KK_SCOA_x`	`1.0e20`
`conversion_factor`	`1.0`
`dGf1_CO2_tot`	`-530.71`
`K_ip`	`4.7e-5`
`KMg_NAD_x`	`1.0e20`
`dGf1_PI`	`-1098.27`
`KK_FAD_x`	`1.0e20`
`minCond`	`1.0e-9`
`dGf1_MAL`	`-842.66`
`K_iADP`	`0.0004`
`KMg_SCOA_x`	`1.0e20`
`C_IM`	`6.75e-6`
`KMg_ACCOA_x`	`1.0e20`
`K_iGLUx`	`0.0016`
`dFAD_x_dt`	`0.0`
`K_iACCOA`	`4.02e-5`
`K_mOAA`	`6.128e-6`
`K_iASPx`	`0.0028`
`K_ir2`	`1000.0`
`KH_OAA_x`	`1.0e20`
`KH_O2_x`	`1.0e20`
`dGf1_COASH`	`-0.72`
`KK_H_x`	`1.0e20`
`dO2_x_dt`	`0.0`
`dGf1_G6P`	`-1758.87`
`KH_FAD_x`	`1.0e20`
`K_mQ`	`0.001`
`dGf1_PCr`	`0.0`
`X_fum`	`0.00707728025683`
`gamma`	`5.99`
`K_K`	`1.0e20`
`KMg_K_x`	`1.0e20`
`dGf1_FADH2`	`-67.6`
`X_PYRH`	`2.996779273769102e8`
`K_iGLUi`	`0.00018`

States:

Name	Description
`AKG_c(time)`	`1.0e-9`
`G6P_c(time)`	`1.0e-9`
`FUM_c(time)`	`1.0e-9`
`ASP_x(time)`	`0.00010217`
`FUM_x(time)`	`7.8476e-9`
`QH2_x(time)`	`0.0`
`GLU_c(time)`	`5.754e-12`
`ICIT_i(time)`	`1.0e-9`
`ADP_i(time)`	`1.0e-9`
`ADP_c(time)`	`1.0e-9`
`AKG_i(time)`	`9.9995e-10`
`SUC_i(time)`	`1.0e-9`
`GDP_x(time)`	`0.005`
`GLU_i(time)`	`5.7539e-12`
`OAA_x(time)`	`0.00089236`
`PI_x(time)`	`0.00029918`
`ADP_x(time)`	`0.01`
`ATP_i(time)`	`1.0e-9`
`SCOA_x(time)`	`6.9627e-10`
`GLU_x(time)`	`9.9311e-12`
`ICIT_c(time)`	`1.0e-9`
`PCr_c(time)`	`1.0e-9`
`CIT_i(time)`	`1.0e-9`
`Cred_i(time)`	`9.6996e-8`
`ACCOA_x(time)`	`2.5507e-12`
`PYR_i(time)`	`9.1804e-10`
`AKG_x(time)`	`4.7979e-11`
`NADH_x(time)`	`8.4842e-21`
`Mg_x(time)`	`0.0046388`
`COASH_x(time)`	`0.0030107`
`MAL_i(time)`	`1.0e-9`
`K_x(time)`	`0.086878`
`H_c(time)`	`1.0e-7`
`MAL_c(time)`	`1.0e-9`
`dPsi(time)`	`-14.087`
`Mg_c(time)`	`0.005`
`ICIT_x(time)`	`9.3558e-7`
`PI_i(time)`	`0.00011574`
`PYR_x(time)`	`1.2076e-11`
`AMP_x(time)`	`1.0e-6`
`PYR_c(time)`	`1.0e-9`
`SUC_c(time)`	`1.0e-9`
`GLC_c(time)`	`1.0e-9`
`CO2_tot_x(time)`	`0.0214`
`ASP_i(time)`	`4.4404e-9`
`CIT_x(time)`	`6.8151e-5`
`FUM_i(time)`	`1.0e-9`
`AMP_c(time)`	`1.0e-9`
`O2_x(time)`	`6.5e-5`
`AMP_i(time)`	`1.0e-9`
`ATP_x(time)`	`1.025e-11`
`SUC_x(time)`	`2.1681e-7`
`CIT_c(time)`	`1.0e-9`
`K_c(time)`	`0.15`
`ATP_c(time)`	`1.0e-9`
`MAL_x(time)`	`3.2191e-8`
`GTP_x(time)`	`2.7157e-10`
`ASP_c(time)`	`4.4404e-9`
`PI_c(time)`	`0.00011574`
`H_x(time)`	`5.7919e-8`

Y

yamaguchi_takaki_matsubara_yasuhara_suga_1996 — v0.0.1

Yamaguchi, Takaki, Matsubara, Yasuhara, Suga, 1996

Details

Parameters:

Name	Description
`f`	`10.0`
`g`	`10.0`
`Ca_max`	`1.0`
`L_0`	`0.0`
`D_Ca`	`0.1`
`L`	`1.0`
`CumCB_on_end`	`1.0`
`Total_CB`	`1.0`
`Total_Tn`	`1.0`
`F_max`	`0.228`
`epsilon`	`1.0`
`phi`	`1.0`
`k_2`	`20.0`
`s`	`1.0`
`k_1`	`40.0`

States:

Name	Description
`TnCa(t)`	`0.0`
`CumCB_off(t)`	`0.0`
`CB_on(t)`	`0.0`
`FTI(t)`	`0.0`
`CumCB_on(t)`	`0.0`

yanagihara_1980 — v0.0.1

Yanagihara 1980

Details

Parameters:

Name	Description
`Cm`	`1.0`

States:

Name	Description
`d(time)`	`3.2e-5`
`V(time)`	`-62.83`
`h(time)`	`0.95994`
`n(time)`	`0.509494`
`m(time)`	`0.047938`
`f(time)`	`1.0`
`q(time)`	`0.010759`

yang_clark_bryan_robertson_2003 — v0.0.1

Yang, Clark, Bryan, Robertson, 2003

Details

Parameters:

Name	Description
`R`	`nothing`
`Kr2`	`nothing`
`K3`	`nothing`
`Kr1`	`nothing`
`T`	`nothing`
`fAM`	`nothing`
`k_1`	`nothing`
`P_Na`	`nothing`
`g_Kb`	`nothing`
`sigma`	`nothing`
`fAMp`	`nothing`
`d_NaCa`	`nothing`
`lc`	`nothing`
`B`	`nothing`
`Km_Nai`	`nothing`
`K_CaCM`	`nothing`
`lopt`	`nothing`
`lx`	`nothing`
`Cm`	`nothing`
`vx`	`nothing`
`Vol_u`	`nothing`
`k_d`	`nothing`
`Vol_i`	`nothing`
`Vol_r`	`nothing`
`g_NaCa`	`nothing`
`Am`	`nothing`
`Ps_infinity`	`nothing`
`kd`	`nothing`
`K4`	`nothing`
`g_K`	`nothing`
`Ca_u`	`nothing`
`tau_Pf`	`nothing`
`B_F_Ca`	`nothing`
`ia`	`nothing`
`tau_tr`	`nothing`
`g_Ca_L`	`nothing`
`Kr2_`	`nothing`
`S_CM_Ca`	`nothing`
`tau_rel`	`nothing`
`Na_o`	`nothing`
`kx2`	`nothing`
`K2`	`nothing`
`g_K_Ca`	`nothing`
`sigma_1_2`	`nothing`
`g_Nab`	`nothing`
`K7`	`nothing`
`Ca_o`	`nothing`
`Km_up`	`nothing`
`Km_Ko`	`nothing`
`l0`	`nothing`
`I_Ca_P`	`nothing`
`K_o`	`nothing`
`G_Ki`	`nothing`
`ls0`	`nothing`
`n_Ki`	`nothing`
`delta_ls`	`nothing`
`ks`	`nothing`
`I_NaK`	`nothing`
`mu_s`	`nothing`
`K5`	`nothing`
`A`	`nothing`
`kp`	`nothing`
`k`	`nothing`
`kx1`	`nothing`
`P_Ca`	`nothing`
`I_up`	`nothing`
`k1`	`nothing`
`g_Cab`	`nothing`
`beta`	`nothing`
`la`	`nothing`
`Vol_Ca`	`nothing`
`alpha_s`	`nothing`
`tau_Ps`	`nothing`
`gamma`	`nothing`
`alpha_p`	`nothing`
`Kr1_`	`nothing`
`V_1_2`	`nothing`
`P_K`	`nothing`
`k_sigma`	`nothing`
`F`	`nothing`

States:

Name	Description
`Mp(time)`	`nothing`
`P1(time)`	`nothing`
`R00(time)`	`nothing`
`ff(time)`	`nothing`
`R01(time)`	`nothing`
`AMp(time)`	`nothing`
`P2(time)`	`nothing`
`Na_i(time)`	`nothing`
`d(time)`	`nothing`
`Pf(time)`	`nothing`
`M(time)`	`nothing`
`R10(time)`	`nothing`
`V(time)`	`nothing`
`ls(time)`	`nothing`
`AM(time)`	`nothing`
`Ps(time)`	`nothing`
`K_i(time)`	`nothing`
`S_CM_cal(time)`	`nothing`
`Ca_r(time)`	`nothing`
`B_F_cal(time)`	`nothing`
`Ca_up(time)`	`nothing`
`Ca_i(time)`	`nothing`
`R11(time)`	`nothing`

yang_tong_mccarver_hines_beard_2006 — v0.0.1

Yang, Tong, Mccarver, Hines, Beard, 2006

Details

Parameters:

Name	Description
`Q`	`1221.34`
`K2`	`0.8532`
`P`	`15.61`
`V`	`1454.0`
`Qc`	`6445.65`
`Km`	`198.0`
`n2`	`1.0`
`age`	`5.0`
`Va`	`2148.0`
`Vv`	`3431.0`
`Vmax`	`0.009433`
`F`	`0.48`

States:

Name	Description
`C(time)`	`0.0`
`Ca(time)`	`6.6685`

yasamura_suga_1987 — v0.0.1

Yasumura, Suga, 1988

Details

yates_stark_klein_antia_callard_2007 — v0.0.1

Yates, Stark, Klein, Antia, Callard, 2007

Details

Parameters:

Name	Description
`v`	`0.5`
`f`	`100.0`
`d1`	`0.005`
`kappa`	`1.0`
`r`	`1.0`
`a`	`0.03333`
`p`	`200.0`
`mu`	`0.023`

States:

Name	Description
`x(time)`	`1.0`
`y(time)`	`0.0`
`z(time)`	`0.01`
`w(time)`	`0.0`

yi_fogelson_keener_peskin_2003 — v0.0.1

Yi, Fogelson, Keener, Peskin, 2003

Details

youm_kim_han_kim_joo_leem_goto_noma_earm_2006 — v0.0.1

Youm, Kim, Han, Kim, Joo, Leem, Goto, Noma, Earm, 2006

Details

Parameters:

Name	Description
`pNaK`	`79.0`
`Na_o`	`140.0`
`T`	`309.15`
`IP3_IP4`	`0.004`
`dt_CellML`	`0.01`
`Ca_o`	`1.8`
`dt`	`0.2`
`pleak`	`0.45`
`I_ext`	`0.0`
`PCaL`	`5.76`
`Pup`	`7728.0`
`PAI`	`15.61`
`Km_Ca_i`	`0.08`
`K_o`	`5.4`
`pPMCA`	`927.4`
`g_Ki`	`4.32`
`PNaCa`	`8.458`
`Km_Ca_o`	`0.002`
`ZNa`	`1.0`
`Vi`	`715.5`
`kci`	`0.000849`
`Km_K_o`	`0.27`
`PIP3R`	`217.2`
`ZK`	`1.0`
`Cm`	`25.0`
`Km_Na_o`	`670000.0`
`koi`	`0.02`
`ptr`	`20.5`
`ZCa`	`2.0`
`IP3total`	`0.0033`
`Km_Na_i`	`670.0`
`PIP2_IP4`	`0.0`
`R`	`8.314`
`F`	`96.485`
`PVDDR`	`7.92`

States:

Name	Description
`Cai_A(time)`	`0.0035`
`Ca_rel(time)`	`13.1`
`h(time)`	`0.0`
`y(time)`	`0.1`
`K_i(time)`	`140.0`
`Vm(time)`	`-68.0`
`m(time)`	`0.0`
`Ca_up(time)`	`4.6`
`PIP2(time)`	`0.002664`
`IP3(time)`	`0.0002682`
`Na_i(time)`	`5.4`

Z

zager_schlosser_tran_2007 — v0.0.1

Zager, Schlosser, Tran, 2007

Details

Parameters:

Name	Description
`Ppp`	`0.59`
`tbasal`	`0.0865`
`cv`	`1.0`
`cgen`	`0.06561`
`kcon_urine`	`0.0`
`m_rat`	`0.25`
`Prp`	`1.94`
`VGI`	`0.011`
`Vpp`	`0.188`
`Km`	`0.6231`
`Pl`	`3.61`
`kgen_urine`	`9.5`
`Vmax`	`25.25`
`Vl`	`0.0092`
`epsilon`	`0.1`
`VROB`	`0.2408`
`ct`	`1.0107`
`kbile`	`111.72`
`Vrp`	`0.012`

States:

Name	Description
`Cgen_l(time)`	`0.0`
`Cgen_GI(time)`	`0.0`
`Cgen_pp(time)`	`0.0`
`Ccon_ROB(time)`	`0.0`
`Acon_b(time)`	`0.0`
`Cgen_rp(time)`	`0.0`
`Ccon_l(time)`	`0.0`

zeng_laurita_rosenbaum_rudy_1995 — v0.0.1

Zeng, Laurita, Rosenbaum, Rudy, 1995

Details

Parameters:

Name	Description
`gamma_Cai`	`nothing`
`gamma_Cao`	`nothing`
`T`	`nothing`
`TRPN_max`	`nothing`
`calcium_overload`	`nothing`
`P_Na`	`nothing`
`Km_Ca`	`nothing`
`delta_Ca_i2`	`nothing`
`K_mup`	`nothing`
`Ca_JSR_old`	`nothing`
`delta_Ca_ith`	`nothing`
`K_sat`	`nothing`
`gamma_Nao`	`nothing`
`tau_on`	`nothing`
`CMDN_max`	`nothing`
`Cm`	`nothing`
`P_ns_Ca`	`nothing`
`R_A_V`	`nothing`
`P_NaK`	`nothing`
`K_mNa`	`nothing`
`eta`	`nothing`
`V_myo`	`nothing`
`tau_tr`	`nothing`
`Ca_NSR_max`	`nothing`
`K_mCa`	`nothing`
`Cao`	`nothing`
`g_Nab`	`nothing`
`K_mpCa`	`nothing`
`gamma_Nai`	`nothing`
`Cai_old`	`nothing`
`K_mCSQN`	`nothing`
`t`	`nothing`
`gamma_Ki`	`nothing`
`I_st`	`nothing`
`K_m_ns_Ca`	`nothing`
`K_mCMDN`	`nothing`
`tau_off`	`nothing`
`A_cap`	`nothing`
`I_pCa`	`nothing`
`I_NaK`	`nothing`
`Nao`	`nothing`
`K_mTRPN`	`nothing`
`K_mNai`	`nothing`
`P_Ca`	`nothing`
`g_Na`	`nothing`
`I_up`	`nothing`
`V_cleft`	`nothing`
`g_Cab`	`nothing`
`CSQN_th`	`nothing`
`g_Kp`	`nothing`
`K_mrel`	`nothing`
`CSQN_max`	`nothing`
`g_Ca_T`	`nothing`
`gamma_Ko`	`nothing`
`K_NaCa`	`nothing`
`K_mKo`	`nothing`
`R`	`nothing`
`P_K`	`nothing`
`F`	`nothing`

States:

Name	Description
`d(time)`	`nothing`
`g(time)`	`nothing`
`delta_Cai(time)`	`nothing`
`V(time)`	`nothing`
`h(time)`	`nothing`
`Ca_NSR(time)`	`nothing`
`c1(time)`	`nothing`
`f(time)`	`nothing`
`b1(time)`	`nothing`
`Xs(time)`	`nothing`
`Ko(time)`	`nothing`
`Ki(time)`	`nothing`
`b(time)`	`nothing`
`j(time)`	`nothing`
`Ca_total(time)`	`nothing`
`m(time)`	`nothing`
`Xr(time)`	`nothing`
`Nai(time)`	`nothing`
`Ca_foot(time)`	`nothing`