CellMLPhysiome: N - S

N

noble_difrancesco_denyer_1989 — v0.0.1

Noble, Difrancesco, Denyer, 1989

Details

Parameters:

Name	Description
`tau_rel`	`0.01`
`V_e_ratio`	`0.1`
`T`	`310.0`
`C`	`6.0e-5`
`I_p`	`0.45`
`n_NaCa`	`3.0`
`Cao`	`2.0`
`Ca_up_max`	`5.0`
`g_Nab`	`0.0007`
`Km_f`	`45.0`
`K_mf2`	`0.0005`
`length`	`0.11`
`d_NaCa`	`0.0001`
`radius`	`0.008`
`g_f_K`	`0.06`
`delta_f`	`0.0001`
`speed_y`	`2.0`
`Km_K1`	`10.0`
`delta_d`	`0.0001`
`Nao`	`140.0`
`alpha_f2`	`10.0`
`K_mK`	`1.0`
`tau_rep`	`0.2`
`P_si`	`0.12`
`g_Na`	`0.0125`
`tau_up`	`0.005`
`rCa`	`2.0`
`K_mNa`	`40.0`
`g_Cab`	`0.0001`
`g_f_Na`	`0.06`
`g_K1`	`0.0075`
`delta_m`	`1.0e-5`
`i_K_max`	`0.8`
`gamma`	`0.5`
`K_NaCa`	`2.0e-5`
`K_mCa`	`0.002`
`R`	`8314.472`
`F`	`96485.3415`
`Kc`	`3.0`

States:

Name	Description
`d(time)`	`1.26333192869164e-5`
`Ca_rel(time)`	`0.177741556496929`
`V(time)`	`-67.797059970601`
`h(time)`	`0.138105285882671`
`f2(time)`	`0.485471180273736`
`x(time)`	`0.129303443591363`
`f(time)`	`0.999507224159629`
`y(time)`	`0.0743464067197738`
`Ki(time)`	`139.859968229045`
`p(time)`	`0.176207580044253`
`m(time)`	`0.042697621819783`
`Ca_up(time)`	`3.70806465918854`
`Cai(time)`	`5.84191784887783e-5`
`Nai(time)`	`7.51007221193712`

noble_noble_1984 — v0.0.1

Noble, Noble, 1984

Details

Parameters:

Name	Description
`T`	`310.0`
`C`	`0.006`
`Ca_up_max`	`5.0`
`length`	`0.08`
`d_NaCa`	`0.0001`
`g_f_K`	`6.0`
`Kb`	`3.0`
`delta_f`	`0.0001`
`delta_x`	`0.0001`
`Km_K1`	`10.0`
`tau_rep`	`0.2`
`tau_up`	`0.005`
`K_mNa`	`40.0`
`g_K1`	`0.75`
`delta_m`	`1.0e-5`
`delta_y`	`1.0e-5`
`K_mCa`	`0.002`
`tau_rel`	`0.01`
`V_e_ratio`	`0.1`
`I_p`	`50.0`
`Cao`	`2.0`
`n_NaCa`	`3.0`
`g_Nab`	`0.07`
`K_mf2`	`0.0005`
`Km_f`	`45.0`
`radius`	`0.08`
`speed_y`	`2.0`
`delta_d`	`0.0001`
`Nao`	`140.0`
`alpha_f2`	`10.0`
`K_mK`	`1.0`
`rCa`	`2.0`
`P_si`	`7.5`
`g_Na`	`1.25`
`g_Cab`	`0.01`
`g_f_Na`	`6.0`
`i_K_max`	`20.0`
`gamma`	`0.5`
`K_NaCa`	`0.002`
`R`	`8314.472`
`V_e`	`0.00016077`
`pf`	`1.0`
`F`	`96485.3415`

States:

Name	Description
`d(time)`	`0.0011`
`Ca_rel(time)`	`0.55`
`V(time)`	`-60.0`
`h(time)`	`0.015`
`f2(time)`	`0.785`
`x(time)`	`0.54`
`f(time)`	`0.785`
`y(time)`	`0.007`
`Kc(time)`	`3.0`
`Ki(time)`	`140.0`
`p(time)`	`0.785`
`m(time)`	`0.076`
`Ca_up(time)`	`1.98`
`Cai(time)`	`5.8e-5`
`Nai(time)`	`7.5`

noble_noble_2001 — v0.0.1

Noble, Noble, 2001

Details

Parameters:

Name	Description
`T`	`310.0`
`stim_start`	`0.1`
`g_Kr2`	`0.0017`
`P_kna`	`0.03`
`alpha_Calmod`	`100000.0`
`g_bca`	`0.00025`
`alpha_Trop`	`100000.0`
`length`	`74.0`
`d_NaCa`	`0.0`
`K_leak_rate`	`0.05`
`alpha_up`	`0.4`
`i_NaK_max`	`0.7`
`g_to`	`0.005`
`delta_f`	`0.0001`
`Trop`	`0.05`
`Cm`	`9.5e-5`
`beta_up`	`0.03`
`FRiNaCa`	`0.001`
`g_Kr1`	`0.0028`
`FrICa`	`0.7`
`K_cyca`	`0.0003`
`beta_Trop`	`200.0`
`K_mNa`	`40.0`
`g_bna`	`0.0006`
`g_Ks`	`0.0016`
`g_K1`	`0.5`
`delta_m`	`1.0e-5`
`P_Ca_L`	`1.0`
`KCaChoff`	`0.01`
`K_srca`	`0.5`
`V_e_ratio`	`0.4`
`Na_o`	`140.0`
`V_ds_ratio`	`0.1`
`stim_duration`	`0.002`
`speed_d`	`3.0`
`Kdecay`	`10.0`
`K_m_rel`	`250.0`
`g_tos`	`0.0`
`n_NaCa`	`3.0`
`Kmdsinact`	`0.001`
`Ca_o`	`2.0`
`shift_h`	`0.0`
`V_up_ratio`	`0.01`
`stim_period`	`1.0`
`stim_end`	`600.0`
`K_mk1`	`10.0`
`K_m_Ca_ds`	`0.01`
`Calmod`	`0.02`
`radius`	`12.0`
`beta_Calmod`	`50.0`
`K_o`	`4.0`
`K_m_Ca_cyt`	`0.0005`
`K_xcs`	`0.4`
`V_rel_ratio`	`0.1`
`P_CaK`	`0.002`
`K_mK`	`1.0`
`g_Na`	`0.5`
`speed_f`	`0.3`
`g_pna`	`0.0027`
`stim_amplitude`	`-6.0`
`P_CaNa`	`0.01`
`gamma`	`0.2`
`k_NaCa`	`0.0005`
`R`	`8314.472`
`F`	`96485.3415`

States:

Name	Description
`d(time)`	`2.27643784381792e-8`
`Ca_Trop(time)`	`0.00013982468565579`
`xr2(time)`	`2.15138346929839e-7`
`Ca_rel(time)`	`0.185609773872992`
`V(time)`	`-93.0550060340878`
`h(time)`	`0.99465397024286`
`xs(time)`	`6.72192033116639e-7`
`f(time)`	`4.03082807230434e-9`
`K_i(time)`	`138.49601832864`
`ProdFrac(time)`	`0.0109931117325847`
`ActFrac(time)`	`0.000183030061767109`
`Ca_ds(time)`	`2.15623822848619e-7`
`r(time)`	`1.8398417043009e-8`
`m(time)`	`0.00157541794600382`
`xr1(time)`	`9.88715446781661e-6`
`Ca_i(time)`	`5.60867201979414e-6`
`s(time)`	`0.999870016703514`
`Ca_up(time)`	`0.187470810108547`
`Na_i(time)`	`5.68929064089788`
`Ca_Calmod(time)`	`0.000221858224298955`

noble_noble_bett_earm_ho_so_1991 — v0.0.1

Noble, Noble, Bett, Earm, Ho, So, 1991

Details

Parameters:

Name	Description
`T`	`310.0`
`stim_start`	`0.1`
`alpha_Calmod`	`100000.0`
`g_bca`	`0.00025`
`alpha_Trop`	`100000.0`
`length`	`0.074`
`d_NaCa`	`0.0`
`K_leak_rate`	`0.0`
`alpha_up`	`0.4`
`i_NaK_max`	`0.7`
`g_to`	`0.005`
`delta_f`	`0.0001`
`Trop`	`0.05`
`Cm`	`9.5e-5`
`beta_up`	`0.03`
`K_m_Ca`	`0.0005`
`K_cyca`	`0.0003`
`beta_Trop`	`200.0`
`K_mNa`	`40.0`
`g_bna`	`0.0006`
`g_K1`	`1.0`
`delta_m`	`1.0e-5`
`P_Ca_L`	`0.25`
`K_srca`	`0.5`
`V_e_ratio`	`0.4`
`Na_o`	`140.0`
`stim_duration`	`0.002`
`g_tos`	`0.0`
`speed_d`	`3.0`
`K_m_rel`	`250.0`
`n_NaCa`	`3.0`
`Ca_o`	`2.0`
`shift_h`	`0.0`
`V_up_ratio`	`0.01`
`stim_period`	`1.0`
`stim_end`	`100.0`
`K_mk1`	`10.0`
`Calmod`	`0.02`
`radius`	`0.012`
`beta_Calmod`	`50.0`
`K_o`	`4.0`
`g_bk`	`0.0006`
`K_xcs`	`0.4`
`V_rel_ratio`	`0.1`
`P_CaK`	`0.002`
`K_mK`	`1.0`
`g_Na`	`2.5`
`speed_f`	`0.5`
`stim_amplitude`	`-6.0`
`i_K_max`	`1.0`
`P_CaNa`	`0.01`
`gamma`	`0.5`
`k_NaCa`	`0.0005`
`R`	`8314.472`
`F`	`96485.3415`

States:

Name	Description
`d(time)`	`1.91821833548952e-8`
`Ca_Trop(time)`	`0.00033477224086766`
`Ca_rel(time)`	`0.591323137897127`
`V(time)`	`-93.7400119196694`
`h(time)`	`0.995414125415674`
`x(time)`	`0.00938586574433011`
`f(time)`	`0.999999956287155`
`K_i(time)`	`136.604284305878`
`ActFrac(time)`	`0.00267040300939318`
`ProdFrac(time)`	`0.522949441962453`
`r(time)`	`1.60424507876553e-8`
`m(time)`	`0.00143405969732302`
`Ca_up(time)`	`0.59333810408885`
`Ca_i(time)`	`1.34858164771406e-5`
`s(time)`	`0.997644968939185`
`Na_i(time)`	`7.50547214142684`
`Ca_Calmod(time)`	`0.000524570960945961`

noble_varghese_kohl_noble_1998 — v0.0.1

Noble, Varghese, Kohl, Noble, 1998

Details

Parameters:

Name	Description
`stim_start`	`0.1`
`cross_bridge_density`	`0.05`
`gama_SAC_IT`	`2.5`
`ITHST`	`1.0`
`K_D`	`0.00013`
`g_Ca_stretch`	`0.01`
`length`	`74.0`
`alpha_Trop`	`100000.0`
`d_NaCa`	`0.0`
`sarcomere_length`	`2.0`
`Km_f2ds`	`0.001`
`delta_f`	`0.0001`
`E_fibro_stretch`	`0.0`
`g_Na_stretch`	`0.01`
`g_Kr1`	`0.0021`
`KCont2`	`100.0`
`g_fibro`	`0.0002`
`K_cyca`	`0.0003`
`beta_Trop`	`200.0`
`K_mNa`	`40.0`
`g_bna`	`0.0006`
`g_K_ATP`	`0.0`
`g_Ks`	`0.0026`
`gama_SAC_SL`	`2.5`
`P_Ca_L`	`0.1`
`g_An_stretch`	`0.01`
`alpha_ACh`	`0.5`
`K_srca`	`0.5`
`ACh`	`5.0`
`Na_o`	`140.0`
`V_ds_ratio`	`0.1`
`speed_d`	`3.0`
`Kdecay`	`10.0`
`K_m_rel`	`250.0`
`shift_h`	`0.0`
`KCont1`	`12000.0`
`g_K_stretch`	`0.01`
`gama_SR_SL`	`2.5`
`K_m_Ca_ds`	`0.01`
`radius`	`12.0`
`SLHST`	`2.0`
`K_m_Ca_cyt`	`0.0005`
`K_xcs`	`0.4`
`P_CaK`	`0.002`
`K_mK`	`1.0`
`speed_f`	`0.3`
`g_KACh`	`0.0`
`KCont4`	`25.0`
`stim_amplitude`	`-3.0`
`KCont3`	`60.0`
`K_ATP`	`0.1`
`Km_f2`	`100000.0`
`P_CaNa`	`0.01`
`c_fibro`	`1.0e-5`
`gama_SR_IT`	`2.5`
`F`	`96485.3415`
`T`	`310.0`
`g_Kr2`	`0.0013`
`P_kna`	`0.03`
`alpha_Calmod`	`100000.0`
`g_bca`	`0.00025`
`g_fibro_stretch`	`0.0`
`K_leak_rate`	`0.005`
`alpha_up`	`0.4`
`i_NaK_max`	`0.7`
`g_to`	`0.005`
`Trop`	`0.05`
`Cm`	`9.5e-5`
`beta_ACh`	`0.5`
`beta_up`	`0.03`
`FRiNaCa`	`0.001`
`shiftK1`	`10.0`
`K_kna`	`20.0`
`FrICa`	`1.0`
`g_K1`	`0.5`
`KTrop`	`5000.0`
`delta_m`	`1.0e-5`
`V_e_ratio`	`0.4`
`ATP`	`0.0`
`stim_duration`	`0.003`
`g_tos`	`0.0`
`steepK1`	`1.25`
`n_NaCa`	`3.0`
`g_K_Na`	`0.0`
`Ca_o`	`2.0`
`R_decay`	`20.0`
`V_up_ratio`	`0.01`
`stim_period`	`1.0`
`stim_end`	`10000.0`
`K_mk1`	`10.0`
`g_fibro_junct`	`0.00029`
`Calmod`	`0.02`
`beta_Calmod`	`50.0`
`K_o`	`4.0`
`gama_Trop_SL`	`1.5`
`E_An_stretch`	`-20.0`
`V_rel_ratio`	`0.1`
`g_Na`	`2.5`
`g_pna`	`0.004`
`gamma`	`0.5`
`k_NaCa`	`0.0005`
`R`	`8314.472`

States:

Name	Description
`V_fibro(time)`	`-20.0`
`x_ACh(time)`	`0.0`
`xs(time)`	`0.001302`
`f(time)`	`1.0`
`ProdFrac(time)`	`0.2854569`
`ActFrac(time)`	`0.001914`
`m(time)`	`0.0016203`
`s(time)`	`0.9948645`
`Na_i(time)`	`7.3321223`
`Ca_Calmod(time)`	`0.0005555`
`d(time)`	`0.0`
`Ca_Trop(time)`	`0.0002`
`xr2(time)`	`2.0e-7`
`Ca_rel(time)`	`0.4481927`
`V(time)`	`-92.849333`
`f2(time)`	`0.9349197`
`h(time)`	`0.9944036`
`K_i(time)`	`136.5644281`
`cross_bridge(time)`	`8.09e-5`
`Ca_ds(time)`	`1.88e-5`
`r(time)`	`0.0`
`xr1(time)`	`1.03e-5`
`Ca_i(time)`	`1.4e-5`
`Ca_up(time)`	`0.4531889`
`f2ds(time)`	`0.9651958`
`light_chain(time)`	`3.32e-5`

novak_csikasznagy_gyorffy_chen_tyson_1998 — v0.0.1

Novak, Csikasznagy, Gyorffy, Chen, Tyson, 1998

Details

Parameters:

Name	Description
`Vwee`	`0.01`
`kaa_`	`1.0`
`k25`	`0.5`
`V2_`	`1.0`
`V25_`	`0.4`
`kir`	`1.0`
`k25r_`	`0.2`
`kad`	`0.1`
`Jmr`	`0.2`
`Vmik`	`0.002`
`k4_`	`0.15`
`kai_`	`0.25`
`kapr_`	`3.0`
`kapr`	`0.04`
`Japr`	`0.01`
`k3`	`0.15`
`km`	`0.1`
`kap`	`4.0`
`kwr_`	`0.2`
`kmr_`	`0.0`
`Vwee_`	`0.93`
`Jm`	`0.2`
`J25r`	`0.2`
`V2c`	`0.03`
`mu`	`0.005776`
`Jaa`	`0.1`
`V2`	`0.03`
`ki`	`200.0`
`kx`	`0.0`
`Vmik_`	`0.2`
`J25`	`0.2`
`alpha`	`0.1`
`V2c_`	`0.16`
`Puc1`	`0.013`
`kaa`	`0.001`
`k4__`	`20.0`
`Jap`	`0.01`
`k1`	`0.03`
`Jw`	`0.2`
`kw`	`0.5`
`Jwr`	`0.2`
`kas`	`0.25`
`Jai`	`0.1`
`V25`	`0.01`

States:

Name	Description
`APC(time)`	`0.0`
`Mik1(time)`	`0.0`
`Rum1(time)`	`0.0`
`Wee1(time)`	`0.0`
`AAE(time)`	`2.0`
`Cdc25P(time)`	`0.0`
`Cdc13_Cdc2(time)`	`1.0`
`Rum1_Cdc13_Cdc2(time)`	`0.0`
`mass(time)`	`1.0`
`Cdc13_P_Cdc2(time)`	`0.0`
`AAE_total(time)`	`2.0`

novak_pataki_ciliberto_tyson_2001 — v0.0.1

Novak, Pataki, Ciliberto, Tyson, 2001

Details

Parameters:

Name	Description
`k14`	`0.1`
`J10`	`0.01`
`Ja25`	`0.01`
`J16`	`0.01`
`k9`	`0.1`
`J15`	`0.01`
`k2__`	`1.0`
`k8`	`0.25`
`J8`	`0.001`
`k16__`	`2.0`
`Viwee`	`1.0`
`k12_`	`1.0`
`Vi25`	`0.25`
`k3__`	`10.0`
`J9`	`0.01`
`k5_`	`0.005`
`k25__`	`5.0`
`k4_`	`2.0`
`k12`	`0.01`
`J4`	`0.01`
`k12__`	`3.0`
`J3`	`0.01`
`kwee__`	`1.3`
`kwee_`	`0.15`
`Vawee`	`0.25`
`Jiwee`	`0.01`
`J5`	`0.3`
`k13`	`0.1`
`k10`	`0.04`
`Jawee`	`0.01`
`k2___`	`0.1`
`k15`	`1.5`
`Kdiss`	`0.001`
`mu`	`0.005`
`k5__`	`0.3`
`Va25`	`1.0`
`k4`	`35.0`
`k6`	`0.1`
`k11`	`0.1`
`k16_`	`1.0`
`J7`	`0.001`
`k1`	`0.03`
`k3_`	`1.0`
`k2_`	`0.03`
`k7`	`1.0`
`Ji25`	`0.01`
`k25_`	`0.05`

States:

Name	Description
`Slp1(time)`	`2.2`
`IEP(time)`	`0.0`
`M(time)`	`1.0`
`Slp1T(time)`	`0.0`
`SK(time)`	`0.0`
`Cdc13T(time)`	`0.2`
`Rum1T(time)`	`0.0`
`Ste9(time)`	`1.0`
`preMPF(time)`	`0.0`

novak_tyson_1993 — v0.0.1

Novak, Tyson, 1993

Details

Parameters:

Name	Description
`ka`	`0.01`
`kcak`	`0.25`
`V2__`	`1.0`
`Vwee_`	`0.1`
`K_c`	`0.01`
`Vwee__`	`1.0`
`kd_antiIE`	`0.095`
`kbPPase`	`0.125`
`Cdc2_T`	`100.0`
`K_d`	`0.01`
`V2_`	`0.015`
`V25_`	`0.1`
`Wee1_T`	`1.0`
`K_e`	`0.3`
`K_f`	`0.3`
`Cdc25_T`	`1.0`
`K_h`	`0.01`
`kfPPase`	`0.1`
`kc`	`0.1`
`K_a`	`0.1`
`khPPase`	`0.087`
`kinh`	`0.025`
`ke`	`0.0133`
`k1AA`	`1.0`
`IE_T`	`1.0`
`k3`	`0.01`
`K_g`	`0.01`
`V25__`	`2.0`
`UbE_T`	`1.0`
`K_b`	`0.1`
`kg`	`0.0065`

States:

Name	Description
`cyclin(time)`	`1.0`
`Wee1_P(time)`	`0.0`
`Tyr15P_dimer(time)`	`0.0`
`UbE(time)`	`0.0`
`MPF_pre(time)`	`0.0`
`Cdc25_P(time)`	`0.0`
`IE_P(time)`	`0.0`
`MPF_active(time)`	`0.0`
`cyclin_Cdc2(time)`	`0.0`

novak_tyson_1997 — v0.0.1

Novak, Tyson, 1997

Details

Parameters:

Name	Description
`V2_`	`0.0075`
`V25_`	`0.025`
`k8`	`10.0`
`Kmc`	`0.1`
`kir`	`0.1`
`ku2`	`1.0`
`k7r`	`0.1`
`k6_`	`0.0`
`Kmir`	`0.01`
`kwr`	`0.25`
`kc`	`1.0`
`Kmwr`	`0.1`
`Kmw`	`0.1`
`Kmur`	`0.01`
`kcr`	`0.25`
`k3`	`0.09375`
`Kmur2`	`0.05`
`V6_`	`0.0375`
`Vw_`	`0.035`
`Kmi`	`0.01`
`kur2`	`0.3`
`Kmp`	`0.001`
`Vw`	`0.35`
`mu`	`0.00495`
`kur`	`0.1`
`k4`	`0.1875`
`ki`	`0.4`
`V2`	`0.25`
`k8r`	`0.1`
`Kmu2`	`0.05`
`Kmcr`	`0.1`
`kp`	`3.25`
`alpha`	`0.25`
`k1`	`0.015`
`k2_`	`0.05`
`beta`	`0.05`
`ku`	`0.2`
`V6`	`7.5`
`kw`	`1.0`
`k7`	`100.0`
`V25`	`0.5`
`k5`	`0.00175`
`Kmu`	`0.01`

States:

Name	Description
`G1K(time)`	`0.0`
`UbE2(time)`	`0.0`
`Cdc25(time)`	`0.0`
`UbE(time)`	`1.0`
`PG2R(time)`	`0.0`
`PG2(time)`	`0.0`
`IE(time)`	`0.0`
`G2K(time)`	`0.0`
`Wee1(time)`	`0.0`
`G2R(time)`	`0.0`
`R(time)`	`0.4`
`G1R(time)`	`0.0`
`mass(time)`	`0.5`

novak_tyson_2004 — v0.0.1

Novak, Tyson, 2004

Details

Parameters:

Name	Description
`k_25`	`1000.0`
`k_2_`	`0.05`
`k_22`	`1.0`
`K_21`	`1.0`
`k_5`	`20.0`
`phi_B`	`2.0`
`lambda_E`	`5.0`
`J_13`	`0.005`
`epsilon`	`1.0`
`lambda_D`	`3.3`
`k_25r`	`10.0`
`gamma_B`	`1.0`
`eta_B`	`1.0`
`k_32`	`1.8`
`J_17`	`0.3`
`k_24`	`1000.0`
`k_26r`	`200.0`
`k_27`	`0.2`
`k_7`	`0.6`
`k_26`	`10.0`
`k_34`	`0.05`
`k_19`	`20.0`
`eta_E`	`0.5`
`k_28`	`0.2`
`k_16`	`0.25`
`k_8_`	`0.1`
`J_3`	`0.01`
`k_3_`	`7.5`
`k_3`	`140.0`
`k_11`	`1.5`
`lambda_B`	`5.0`
`E2FT`	`5.0`
`k_4`	`40.0`
`J_15`	`0.1`
`lambda_A`	`3.0`
`J_32`	`0.01`
`Rb_T`	`10.0`
`eta_A`	`0.5`
`k_6`	`100.0`
`J_8`	`0.1`
`J_1`	`0.1`
`k_1`	`0.6`
`k_23_`	`0.005`
`phi_E`	`25.0`
`k_29`	`0.05`
`k_30`	`20.0`
`k_13`	`5.0`
`k_19_`	`0.0`
`k_15`	`0.25`
`J_14`	`0.005`
`k_20`	`10.0`
`J_31`	`0.01`
`gamma_A`	`0.3`
`k_24r`	`10.0`
`k_10`	`5.0`
`k_31`	`0.7`
`psi_B`	`0.05`
`k_9`	`2.5`
`k_2__`	`1.0`
`k_18`	`10.0`
`k_7_`	`0.0`
`k_1_`	`0.1`
`k_2`	`20.0`
`k_11_`	`0.0`
`k_12`	`1.5`
`PP1_T`	`1.0`
`k_33`	`0.05`
`J_4`	`0.01`
`k_6_`	`10.0`
`k_17_`	`0.35`
`mu`	`0.061`
`k_23`	`1.0`
`k_8`	`2.0`
`k_14`	`2.5`
`psi_E`	`1.0`
`k_17`	`10.0`

States:

Name	Description
`Kip1(time)`	`nothing`
`E2F(time)`	`nothing`
`CycE_Kip1(time)`	`nothing`
`ERG(time)`	`nothing`
`Cdh1(time)`	`nothing`
`Cdc20(time)`	`nothing`
`PPX(time)`	`nothing`
`GM(time)`	`nothing`
`IEP(time)`	`nothing`
`CycE(time)`	`nothing`
`CycA_Kip1(time)`	`nothing`
`DRG(time)`	`nothing`
`CycB(time)`	`nothing`
`CycD_Kip1(time)`	`nothing`
`mass(time)`	`nothing`
`CycA(time)`	`nothing`
`CycD(time)`	`nothing`
`Cdc20_T(time)`	`nothing`

nowak_bangham_1996 — v0.0.1

Nowak, Bangham, 1996

Details

Parameters:

Name	Description
`beta`	`0.02`
`c`	`1.0`
`k`	`1.0`
`b`	`0.05`
`lambda`	`1.0`
`u`	`1.0`
`a`	`0.5`
`p`	`1.0`
`d`	`0.01`

States:

Name	Description
`v(time)`	`10.0`
`x(time)`	`100.0`
`y(time)`	`0.0`
`z(time)`	`1.0`

nygren_fiset_firek_clark_lindblad_clark_giles_1998 — v0.0.1

Nygren, Fiset, Firek, Clark, Lindblad, Clark, Giles, 1998

Details

Parameters:

Name	Description
`k_Ca`	`0.025`
`T`	`306.15`
`stim_start`	`0.1`
`P_Na`	`0.0016`
`tau_K`	`10.0`
`Mg_i`	`2.5`
`d_NaCa`	`0.0003`
`tau_di`	`0.01`
`k_NaK_K`	`1.0`
`alpha_rel`	`200000.0`
`i_NaK_max`	`70.8253`
`I_up_max`	`2800.0`
`phi_Na_en`	`-1.68`
`k_CaP`	`0.0002`
`Cm`	`0.05`
`Ca_b`	`1.8`
`Vol_rel`	`4.41e-5`
`Vol_i`	`0.005884`
`Na_b`	`130.0`
`Vol_up`	`0.0003969`
`g_Ks`	`1.0`
`g_K1`	`3.0`
`k_xcs`	`0.4`
`tau_tr`	`0.01`
`g_Kr`	`0.5`
`k_rel_i`	`0.0003`
`g_sus`	`2.75`
`g_Ca_L`	`6.75`
`stim_duration`	`0.006`
`g_B_Na`	`0.060599`
`k_rel_d`	`0.003`
`stim_period`	`1.0`
`stim_end`	`1.0e8`
`k_NaK_Na`	`11.0`
`k_srca`	`0.5`
`g_t`	`7.5`
`tau_Ca`	`24.7`
`r_recov`	`0.815`
`i_CaP_max`	`4.0`
`g_B_Ca`	`0.078681`
`stim_amplitude`	`-280.0`
`tau_Na`	`14.3`
`k_cyca`	`0.0003`
`E_Ca_app`	`60.0`
`gamma`	`0.45`
`k_NaCa`	`0.0374842`
`R`	`8314.0`
`F`	`96487.0`
`K_b`	`5.4`

States:

Name	Description
`O_TC(time)`	`0.0133`
`f_L_2(time)`	`0.9986`
`f_L_1(time)`	`0.9986`
`O_Calse(time)`	`0.4369`
`n(time)`	`0.0048357`
`d_L(time)`	`1.3005e-5`
`m(time)`	`0.0032017`
`s(time)`	`0.949`
`Na_i(time)`	`8.5547`
`O_C(time)`	`0.0275`
`r_sus(time)`	`0.00015949`
`Ca_rel(time)`	`0.6465`
`h2(time)`	`0.8742`
`O_TMgMg(time)`	`0.7094`
`V(time)`	`-74.2525`
`K_c(time)`	`5.3581`
`p_a(time)`	`0.0001`
`Ca_c(time)`	`1.8147`
`K_i(time)`	`129.435`
`Ca_d(time)`	`7.2495e-5`
`s_sus(time)`	`0.9912`
`r(time)`	`0.0010678`
`F1(time)`	`0.4284`
`h1(time)`	`0.8814`
`Na_c(time)`	`130.011`
`Ca_up(time)`	`0.6646`
`Ca_i(time)`	`6.729e-5`
`F2(time)`	`0.0028`
`O_TMgC(time)`	`0.1961`

O

obeyesekere_zimmerman_tecarro_auchmuty_1999 — v0.0.1

Obeyesekere, Zimmerman, Tecarro, Auchmuty, 1999

Details

Parameters:

Name	Description
`d_X`	`1.04`
`f`	`0.2`
`g`	`0.528`
`p_S`	`0.6`
`a_f`	`0.9`
`a_X`	`0.08`
`q_X`	`0.8`
`k`	`0.05`
`p_E`	`0.096`
`p_X`	`0.48`
`q_D`	`0.6`
`p_D`	`0.48`
`a_E`	`0.16`
`theta`	`1.5`
`R_T`	`2.5`
`a_D`	`0.4`
`d_E`	`0.2`
`GF`	`6.3`
`d_D`	`0.4`
`q_E`	`0.6`

States:

Name	Description
`E(time)`	`0.6`
`X(time)`	`0.7`
`R(time)`	`0.5`
`R_S(time)`	`1.0`
`D(time)`	`0.1`

olsen_hauser_kummer_2003 — v0.0.1

Olsen, Hauser, Kummer, 2003

Details

Parameters:

Name	Description
`k14`	`700000.0`
`k10`	`1.8e6`
`k9`	`6.0e7`
`k13`	`0.006`
`k12`	`8.0e-8`
`k1`	`3.0`
`k8`	`4.0e7`
`k4`	`5200.0`
`k3`	`150000.0`
`k7`	`2.0e7`
`k13_`	`0.006`
`k6`	`1.7e7`
`O2eq`	`1.2e-5`
`k5`	`2.0e7`
`k2`	`1.8e7`
`k11`	`100000.0`

States:

Name	Description
`coII(time)`	`2.6e-8`
`NAD_radical(time)`	`5.0e-10`
`Per2(time)`	`1.0e-10`
`Ar_radical(time)`	`1.2e-7`
`NAD2(time)`	`1.2e-7`
`O2(time)`	`5.33e-6`
`O2_radical(time)`	`2.6e-8`
`Per3(time)`	`5.9e-8`
`NAD(time)`	`0.000558`
`ArH(time)`	`0.00029988`
`coI(time)`	`8.9e-10`
`H2O2(time)`	`1.3e-8`
`coIII(time)`	`1.31e-6`
`NADH(time)`	`9.5e-7`

oomens_maenhout_vanoijen_drost_baaijens_2003 — v0.0.1

Oomens, Maenhout, Vanoijen, Drost, Baaijens, 2003

Details

ostby_oyehaug_einevoll_nagelhus_plahte_zeuthen_voipio_lloyd_ottersen_omholt_2008 — v0.0.1

Ostby, Oyehaug, Einevoll, Nagelhus, Plahte, Zeuthen, Voipio, Lloyd, Ottersen, Omholt, 2008

Details

Parameters:

Name	Description
`t0`	`10.0`
`Xi`	`12.41`
`T`	`300.0`
`nA`	`6.0221415e23`
`gNBC`	`9.03e-5`
`theta_KCC1`	`1.0`
`elementary_charge`	`1.6e-19`
`gCl`	`8.797e-5`
`gNa`	`0.0001314`
`K_Nai`	`10.0`
`K_Ko`	`1.5`
`Lp`	`0.00021`
`Pmax`	`1.4207e-10`
`gK`	`0.004`
`kc`	`0.0735`
`w_tot`	`0.0879`
`theta_NBC`	`1.0`
`theta_NKCC1`	`1.0`
`t2`	`30.0`
`alpha`	`2.0`
`t1`	`20.0`
`beta`	`14.0`
`gKCC1`	`1.0e-6`
`gNKCC1`	`5.54e-6`
`R`	`8.315`
`zNBC`	`-1.0`
`F`	`96490.0`

States:

Name	Description
`N_Cli(time)`	`0.32879`
`wi(time)`	`0.061`
`N_HCO3i(time)`	`0.58804`
`N_Nai(time)`	`0.99796`
`N_Ko(time)`	`0.0807`
`N_Ki(time)`	`5.52782`
`N_HCO3o(time)`	`0.432552`
`N_Nao(time)`	`4.301041`

overgaard_2007 — v0.0.1

Overgaard 2007

Details

Parameters:

Name	Description
`pEtot`	`0.144`
`kR`	`5.35`
`c`	`3.47`
`t_prime`	`45.12`
`Ts`	`2.45`
`M_b`	`3.0`
`tdose3`	`120.0`
`Nf`	`4.0`
`day_length`	`86400.0`
`delta_T`	`1.57`
`t_night`	`6.73`
`AMT_dose`	`3.0`
`tdose1`	`24.0`
`t_day`	`17.5`
`pEf1`	`1.0`
`Ns`	`4.0`
`pEf2`	`3.57`
`alpha`	`0.2229166`
`T_b`	`38.0`
`pEs2`	`2.43`
`kinc`	`0.0258`
`T_a`	`21.0`
`km`	`1.1375`
`pEf3`	`8.0`
`delta_high_dose`	`1.0`
`tdose2`	`72.0`
`Tf`	`0.368`
`pEs1`	`0.2`
`pEs3`	`50.0`

States:

Name	Description
`M(time)`	`3.5`
`T(time)`	`38.785`
`BR(time)`	`0.0`

oyehaug_ostby_lloyd_omholt_einevoll_2011 — v0.0.1

Oyehaug, Ostby, Lloyd, Omholt, Einevoll, 2011

Details

Parameters:

Name	Description
`P_Ko`	`3.0`
`t0`	`100.0`
`T`	`300.0`
`gNBC`	`80.0`
`P_Kg`	`100.0`
`P_wn`	`0.05`
`Xg`	`8.45`
`gCl`	`50.0`
`gNa`	`100.0`
`P_Vm_g`	`-85.0`
`P_Cln`	`50.0`
`gleakf`	`10.0`
`gKDR`	`5000.0`
`P_Kn`	`130.0`
`P_wg`	`0.05`
`Lp`	`2.0e-8`
`gK`	`1696.0`
`KmNa`	`10.0`
`KmK`	`1.5`
`Cm`	`1.0`
`P_Nan`	`10.0`
`I_NaKATPase_n_max`	`0.0289`
`gNaT`	`5000.0`
`gleakK`	`66.06`
`P_Nao`	`146.0`
`gNaP`	`150.0`
`P_HCO3o`	`15.0`
`P_wo`	`0.025`
`rho`	`0.5975`
`tau_activation`	`6.0`
`Ef_n`	`-70.0`
`gleakNa`	`20.0`
`t1`	`900.0`
`gKA`	`1000.0`
`I_NaKATPase_g_max`	`0.1151`
`gNKCC1`	`2.0`
`R`	`8.315`
`P_Nag`	`15.0`
`F`	`96490.0`

States:

Name	Description
`wg(time)`	`0.05`
`N_Nag(time)`	`0.75`
`N_Kg(time)`	`5.0`
`n(time)`	`0.0012`
`m(time)`	`0.005`
`N_Ko(time)`	`0.075`
`h(time)`	`0.9718`
`Vm_n(time)`	`-70.0`
`N_HCO3o(time)`	`0.375`
`N_Nao(time)`	`3.65`

oyehaug_ostby_lloyd_ottersen_omholt_einevoll_2009 — v0.0.1

Oyehaug, Ostby, Lloyd, Ottersen, Omholt, Einevoll, 2009

Details

Potassium-mediated positive feedback in astroglia-neuron interaction

Parameters:

Name	Description
`P_Ko`	`3.0`
`t0`	`100.0`
`T`	`300.0`
`gNBC`	`80.0`
`P_Kg`	`100.0`
`P_wn`	`0.05`
`Xg`	`8.45`
`gCl`	`50.0`
`gNa`	`100.0`
`P_Vm_g`	`-85.0`
`P_Cln`	`50.0`
`gleakf`	`10.0`
`gKDR`	`5000.0`
`P_Kn`	`130.0`
`P_wg`	`0.05`
`Lp`	`2.0e-8`
`gK`	`1696.0`
`KmNa`	`10.0`
`KmK`	`1.5`
`Cm`	`1.0`
`P_Nan`	`10.0`
`I_NaKATPase_n_max`	`0.0289`
`gNaT`	`5000.0`
`gleakK`	`66.06`
`P_Nao`	`146.0`
`gNaP`	`150.0`
`P_HCO3o`	`15.0`
`P_wo`	`0.025`
`rho`	`0.5975`
`tau_activation`	`6.0`
`Ef_n`	`-70.0`
`gleakNa`	`20.0`
`t1`	`900.0`
`gKA`	`1000.0`
`I_NaKATPase_g_max`	`0.1151`
`gNKCC1`	`2.0`
`R`	`8.315`
`P_Nag`	`15.0`
`F`	`96490.0`

States:

Name	Description
`wg(time)`	`0.05`
`N_Nag(time)`	`0.75`
`N_Kg(time)`	`5.0`
`n(time)`	`0.0012`
`m(time)`	`0.005`
`N_Ko(time)`	`0.075`
`h(time)`	`0.9718`
`Vm_n(time)`	`-70.0`
`N_HCO3o(time)`	`0.375`
`N_Nao(time)`	`3.65`

P

paci_hyttinen_aaltosetala_severi_2013 — v0.0.1

paci_hyttinen_aaltosetala_severi_2013

Details

Parameters:

Name	Description
`nifed_10nM`	`0.0`
`T`	`310.0`
`c_rel`	`8.232`
`PNaK`	`1.841424`
`Buf_C`	`0.25`
`Chromanol_iKs70`	`0.0`
`i_stim_Amplitude`	`5.5e-10`
`Kbuf_SR`	`0.3`
`tau_g`	`0.002`
`a_rel`	`16.464`
`Ko`	`5.4`
`nifed_30nM`	`0.0`
`g_to`	`29.9038`
`Cm`	`9.87109e-11`
`E4031_100nM`	`0.0`
`Chromanol_iKs90`	`0.0`
`TTX_3uM`	`0.0`
`Chromanol_iKs50`	`0.0`
`KmNai`	`87.5`
`tau_fCa`	`0.002`
`b_rel`	`0.25`
`TTX_10uM`	`0.0`
`g_Ks`	`2.041`
`VmaxUp`	`0.56064`
`i_stim_PulseDuration`	`0.005`
`g_K1`	`28.1492`
`g_Kr`	`29.8667`
`Kup`	`0.00025`
`E_f`	`-0.017`
`Kbuf_C`	`0.001`
`Km_Na`	`40.0`
`L0`	`0.025`
`g_b_Ca`	`0.69264`
`Q`	`2.3`
`Cao`	`1.8`
`KPCa`	`0.0005`
`V_SR`	`583.73`
`Ki`	`150.0`
`KmCa`	`1.38`
`i_stim_frequency`	`60.0`
`g_b_Na`	`0.9`
`nifed_100nM`	`0.0`
`i_stim_End`	`800.0`
`Vc`	`8800.0`
`Buf_SR`	`10.0`
`Ksat`	`0.1`
`PkNa`	`0.03`
`Nao`	`151.0`
`i_stim_Start`	`0.0`
`alpha`	`2.8571432`
`E4031_30nM`	`0.0`
`g_Na`	`3671.2302`
`g_f`	`30.10312`
`nifed_3nM`	`0.0`
`g_PCa`	`0.4125`
`V_leak`	`0.00044444`
`kNaCa`	`4900.0`
`Chromanol_iKs30`	`0.0`
`Km_K`	`1.0`
`TTX_30uM`	`0.0`
`g_CaL`	`8.635702e-5`
`gamma`	`0.35`
`stim_flag`	`0.0`
`R`	`8.314472`
`F`	`96485.3415`

States:

Name	Description
`d(time)`	`8.96088425225182e-5`
`g(time)`	`0.999999981028517`
`Xr1(time)`	`0.00778547011240132`
`h(time)`	`0.786926637881461`
`f2(time)`	`0.999965815466749`
`f1(time)`	`0.970411811263976`
`Xs(time)`	`0.0322944866983666`
`fCa(time)`	`0.998925296531804`
`Xr2(time)`	`0.432162576531617`
`r(time)`	`0.00573289893326379`
`j(time)`	`0.253943221774722`
`Xf(time)`	`0.100615100568753`
`Vm(time)`	`-0.0743340057623841`
`m(time)`	`0.102953468725004`
`Ca_SR(time)`	`-0.2734234751931`
`Cai(time)`	`1.80773974140477e-5`
`Nai(time)`	`10.9248496211574`
`q(time)`	`0.839295925773219`

palecek_horwitz_lauffenburger_1999 — v0.0.1

Palecek, Horwitz, Lauffenburger, 1999

Details

pandit_clark_giles_demir_2001 — v0.0.1

Pandit, Clark, Giles, Demir, 2001

Details

Parameters:

Name	Description
`k_a_minus`	`576.0`
`K_mEGTA`	`0.00015`
`stim_start`	`0.1`
`T`	`295.0`
`tau_Ca_inact`	`0.009`
`K_m_K`	`1.5`
`K_SR`	`0.55`
`Vmaxr`	`0.9`
`k_htrpn_plus`	`200000.0`
`d_NaCa`	`0.0001`
`k_b_minus`	`1930.0`
`i_NaK_max`	`0.0504`
`Cm`	`0.0001`
`k_htrpn_minus`	`0.066`
`g_B_K`	`0.000138`
`g_K_slow`	`0.014`
`V_NSR`	`5.04e-7`
`LTRPN_tot`	`0.07`
`V_myo`	`9.36e-6`
`EGTA_tot`	`0.0`
`g_K1`	`0.024`
`g_Ca_L`	`0.025916`
`tau_tr`	`0.0005747`
`k_b_plus`	`4.05e9`
`k_c_plus`	`100.0`
`k_c_minus`	`0.8`
`i_Ca_P_max`	`0.004`
`a_endo`	`0.583`
`k_a_plus`	`1.215e13`
`Na_o`	`140.0`
`stim_duration`	`0.005`
`E_Ca`	`65.0`
`v1`	`1800.0`
`b`	`0.31`
`g_B_Na`	`0.000100188`
`g_ss`	`0.005929`
`V_SS`	`1.2e-9`
`Ca_o`	`1.2`
`tau_xfer`	`0.0267`
`a`	`0.69`
`V_JSR`	`5.6e-8`
`stim_end`	`10.0`
`stim_period`	`1.0`
`b_endo`	`0.417`
`K_mCSQN`	`0.8`
`f_Na`	`0.2`
`K_mCMDN`	`0.00238`
`K_o`	`5.4`
`K_fb`	`0.000168`
`k_ltrpn_minus`	`40.0`
`CSQN_tot`	`15.0`
`K_m_Na`	`10.0`
`k_ltrpn_plus`	`40000.0`
`g_t`	`0.02975`
`CMDN_tot`	`0.05`
`N_fb`	`1.2`
`HTRPN_tot`	`0.14`
`N_rb`	`1.0`
`Vmaxf`	`0.032`
`g_B_Ca`	`1.62e-5`
`g_f`	`0.00145`
`g_Na`	`1.064`
`K_rb`	`3.29`
`stim_amplitude`	`-0.6`
`E_Ca_L`	`65.0`
`m`	`3.0`
`gamma_NaCa`	`0.5`
`K_NaCa`	`9.984e-6`
`R`	`8314.5`
`F`	`96487.0`
`n`	`4.0`

States:

Name	Description
`P_C1(time)`	`0.6348229`
`Ca_ss(time)`	`8.737212e-5`
`Ca_NSR(time)`	`0.06600742`
`P_C2(time)`	`0.3647471`
`y(time)`	`0.003578708`
`s_slow(time)`	`0.6421196`
`HTRPNCa(time)`	`0.1394301`
`f_11(time)`	`0.9999529`
`j(time)`	`0.6729362`
`s_K_slow(time)`	`0.314`
`m(time)`	`0.004164108`
`s(time)`	`0.9842542`
`Na_i(time)`	`10.73519`
`d(time)`	`2.171081e-6`
`LTRPNCa(time)`	`0.0051619`
`V(time)`	`-80.50146`
`h(time)`	`0.6735613`
`r_ss(time)`	`0.002907171`
`f_12(time)`	`0.9999529`
`s_ss(time)`	`0.3142767`
`K_i(time)`	`139.2751`
`Ca_JSR(time)`	`0.06607948`
`P_O1(time)`	`0.0004327548`
`r(time)`	`0.002191519`
`r_K_slow(time)`	`0.642`
`Ca_i(time)`	`7.901351e-5`
`P_O2(time)`	`6.06254e-10`
`Ca_inact(time)`	`0.9913102`

pandit_giles_demir_2003 — v0.0.1

Pandit, Giles, Demir, 2003

Details

Parameters:

Name	Description
`g_ss_normal`	`0.0077`
`k_a_minus`	`576.0`
`K_mEGTA`	`0.00015`
`stim_start`	`0.1`
`T`	`295.0`
`tau_Ca_inact`	`0.009`
`K_m_K`	`1.5`
`K_SR_normal`	`1.0`
`g_t_normal`	`0.04375`
`Vmaxr`	`0.9`
`k_htrpn_plus`	`200000.0`
`g_Ca_L_normal`	`0.0341`
`d_NaCa`	`0.0001`
`k_b_minus`	`1930.0`
`Diabetes`	`0.0`
`Cm`	`0.0001`
`k_htrpn_minus`	`0.066`
`g_B_K`	`0.000138`
`V_NSR`	`5.04e-6`
`Vmaxf_normal`	`0.04`
`i_NaK_max_normal`	`0.08`
`LTRPN_tot`	`0.07`
`V_myo`	`9.36e-6`
`EGTA_tot`	`10.0`
`g_K1`	`0.024`
`k_b_plus`	`4.05e9`
`tau_tr`	`0.0005747`
`k_c_plus`	`100.0`
`k_c_minus`	`0.8`
`i_Ca_P_max`	`0.004`
`k_a_plus`	`1.215e13`
`Na_o`	`140.0`
`stim_duration`	`0.005`
`v1`	`1800.0`
`Ca_o`	`1.2`
`V_SS`	`1.2e-8`
`tau_xfer`	`0.0267`
`V_JSR`	`5.6e-7`
`stim_end`	`10.0`
`stim_period`	`1.0`
`K_mCSQN`	`0.8`
`f_Na`	`0.2`
`K_mCMDN`	`0.00238`
`K_o`	`5.4`
`K_fb`	`0.000168`
`k_ltrpn_minus`	`40.0`
`CSQN_tot`	`15.0`
`K_m_Na`	`10.0`
`k_ltrpn_plus`	`40000.0`
`CMDN_tot`	`0.05`
`N_fb`	`1.2`
`HTRPN_tot`	`0.14`
`N_rb`	`1.0`
`g_Na`	`1.064`
`g_f`	`0.00145`
`g_B_Na_normal`	`8.015e-5`
`K_rb`	`3.29`
`stim_amplitude`	`-0.6`
`E_Ca_L`	`65.0`
`m`	`3.0`
`gamma_NaCa`	`0.5`
`g_B_Ca_normal`	`3.24e-5`
`K_NaCa`	`9.984e-6`
`R`	`8314.5`
`F`	`96487.0`
`n`	`4.0`

States:

Name	Description
`P_C1(time)`	`0.6348229`
`Ca_ss(time)`	`8.737212e-5`
`Ca_NSR(time)`	`0.06600742`
`P_C2(time)`	`0.3647471`
`y(time)`	`0.003578708`
`s_slow(time)`	`0.6421196`
`HTRPNCa(time)`	`0.1394301`
`f_11(time)`	`0.9999529`
`j(time)`	`0.6729362`
`m(time)`	`0.004164108`
`s(time)`	`0.9842542`
`Na_i(time)`	`10.73519`
`d(time)`	`2.171081e-6`
`LTRPNCa(time)`	`0.0051619`
`V(time)`	`-80.50146`
`h(time)`	`0.6735613`
`r_ss(time)`	`0.002907171`
`f_12(time)`	`0.9999529`
`s_ss(time)`	`0.3142767`
`K_i(time)`	`139.2751`
`Ca_JSR(time)`	`0.06607948`
`P_O1(time)`	`0.0004327548`
`r(time)`	`0.002191519`
`Ca_i(time)`	`7.901351e-5`
`P_O2(time)`	`6.06254e-10`
`Ca_inact(time)`	`0.9913102`

panerai_1980 — v0.0.1

Panerai, 1980

Details

Parameters:

Name	Description
`a_1`	`200.0`
`c_2_0`	`20.0`
`x`	`10.0`
`beta_p`	`20.0`
`x_po`	`0.221`
`t_d`	`0.3`
`h`	`12.0`
`beta_s`	`20.0`
`b_1`	`5.0`
`k_i`	`30.9`
`g_2`	`240.0`
`c_1`	`2.0e14`
`Ca_0`	`4.5e-7`
`x_so`	`0.0387`
`q`	`1.45`
`L_max`	`1.0`
`AT_0`	`2.0`
`g_1`	`40.0`
`alpha_s`	`0.1027`
`f_1`	`70.0`
`alpha_p`	`0.00224`
`F_PL`	`3.0`

States:

Name	Description
`A_c(t)`	`1.0`
`n(t)`	`0.0`

parent_supplisson_loo_wright_1992 — v0.0.1

Parent, Supplisson, Loo, Wright, 1992

Details

Electrogenic properties of the cloned Na+/Glucose cotransporter: II. A transport model under nonrapid equilibrium conditions.

Parameters:

Name	Description
`k0_54`	`1.83e7`
`k0_56`	`10.0`
`Na_o`	`0.14`
`k0_21`	`500.0`
`T`	`310.0`
`Na_i`	`0.0196`
`k0_34`	`50.0`
`k0_16`	`35.0`
`delta`	`0.7`
`z_c`	`-2.0`
`k0_25`	`0.3`
`z_Na`	`1.0`
`k0_12`	`80000.0`
`alpha_pp`	`0.0`
`k0_45`	`800.0`
`k0_43`	`50.0`
`k0_65`	`50.0`
`k0_32`	`20.0`
`glucose_o`	`0.005`
`glucose_i`	`0.0151`
`k0_61`	`5.0`
`area`	`1.0e6`
`N_Avo`	`6.022e23`
`k0_23`	`100000.0`
`k0_52`	`1.37`
`N_C`	`6.0e10`
`R`	`8.314`
`F`	`96485.34`
`n`	`2.0`

States:

Name	Description
`C_1(time)`	`1.505e-8`
`C_3(time)`	`2.4603e-10`
`V(time)`	`-0.0554`
`C_2(time)`	`7.3976e-8`
`C_5(time)`	`1.5338e-9`
`C_6_temp(time)`	`8.484e-9`
`C_4(time)`	`3.4444e-10`

pasek_simurda_christe_2006 — v0.0.1

Pasek, Simurda, Christe, 2006

Details

pasek_simurda_orchard_christe_2008 — v0.0.1

Pasek, Simurda, Orchard, Christe, 2008

Details

Parameters:

Name	Description
`f`	`300.0`
`fKNat`	`0.526`
`T`	`310.0`
`g_Naps`	`0.0053`
`fK1t`	`0.8`
`f2`	`5.0`
`fNabt`	`0.526`
`tau_K`	`0.2`
`K_e`	`5.4`
`kcm`	`0.8`
`i_NaCa_max`	`0.00025`
`omega`	`10.0`
`kam`	`576.0`
`i_NaK_max`	`1.5`
`g_KATP`	`1.0`
`Na_e`	`140.0`
`g`	`2000.0`
`P_nsK`	`1.75e-7`
`fCaLt`	`0.64`
`fKATPt`	`0.526`
`q_Ks`	`0.1975`
`rt`	`1.4815e-5`
`fnsKt`	`0.526`
`fNapst`	`0.526`
`ATP_i`	`6.8`
`fNaKt`	`0.526`
`P_nsNa`	`1.75e-7`
`P_KL`	`4.8e-6`
`fCabt`	`0.526`
`tau_r2`	`0.02`
`g_K1`	`0.75`
`tau_tr`	`0.03448`
`fNaCat`	`0.526`
`stim_Period`	`1.0`
`Lt`	`0.000593`
`fpCat`	`0.2`
`q_Kr`	`0.8`
`fKtot`	`0.526`
`fnsNat`	`0.526`
`P_CaL`	`0.0048`
`fNat`	`0.64`
`tau_r3`	`0.08`
`tau_d`	`0.003125`
`b`	`2.0`
`i_pCa_max`	`1.15`
`g_Nab`	`0.00075`
`a`	`2.0`
`PRNaK`	`0.01833`
`fr2`	`1.0`
`Ca_e`	`1.8`
`kbm`	`1930.0`
`g2`	`7000.0`
`ptcm`	`2.1028875e7`
`rc`	`0.000593`
`g_KNa`	`0.12848`
`kcp`	`18.0`
`tau_Ca`	`0.24`
`fKst`	`0.526`
`g_Na`	`30.0`
`Rot`	`83.33`
`fKrt`	`0.526`
`g_Cab`	`0.0021`
`Lc`	`0.013`
`g_Kp`	`0.006`
`g_Kto`	`0.0`
`tau_Na`	`0.2`
`fKpt`	`0.526`
`R`	`8310.0`
`F`	`96500.0`

States:

Name	Description
`Na_t(time)`	`139.93239`
`Cca2(time)`	`6.615513e-11`
`Cca1(time)`	`5.8135383e-7`
`TC1(time)`	`7.5720257e-5`
`CaSRrel(time)`	`1.0326252`
`TCca4(time)`	`4.6165955e-19`
`CaSRup(time)`	`1.0200296`
`K_t(time)`	`5.4140321`
`C3(time)`	`2.7463178e-14`
`y(time)`	`0.7813477`
`Vm_t(time)`	`-85.208034`
`Cca4(time)`	`4.6640361e-19`
`r3(time)`	`0.96250049`
`r2(time)`	`0.9625701`
`F4(time)`	`0.19442578`
`C1(time)`	`7.5722514e-5`
`TCca2(time)`	`6.6150547e-11`
`Ccast(time)`	`0.0019155065`
`TCcast(time)`	`0.0019155245`
`TCca3(time)`	`3.3423167e-15`
`Ca_t(time)`	`1.8476402`
`F2(time)`	`0.00026639195`
`BTRL(time)`	`0.081740868`
`Cca3(time)`	`3.3426555e-15`
`Cst(time)`	`0.99797984`
`xr(time)`	`0.00020469344`
`F3(time)`	`4.9455459e-10`
`Ca_ss(time)`	`9.5977033e-5`
`xs(time)`	`0.0061359896`
`C2(time)`	`2.1545646e-9`
`TCcao(time)`	`3.75926e-22`
`TCst(time)`	`0.99798934`
`TCo(time)`	`-1.3449454e-17`
`TC4(time)`	`-5.7367189e-17`
`m(time)`	`0.0034129472`
`C4(time)`	`-5.7569102e-17`
`Na_i(time)`	`11.120279`
`TCca1(time)`	`5.8133643e-7`
`h(time)`	`0.82699973`
`TC3(time)`	`2.7459475e-14`
`Vm_s(time)`	`-85.207812`
`BTRH(time)`	`0.96700747`
`K_i(time)`	`136.78926`
`Ccao(time)`	`3.7986638e-22`
`TC2(time)`	`2.1544156e-9`
`Co(time)`	`-1.3496934e-17`
`F1(time)`	`0.8053082`
`Ca_i(time)`	`8.8787034e-5`

pedersen_bertram_sherman_2005 — v0.0.1

Pedersen, Bertram, Sherman, 2005

Details

Parameters:

Name	Description
`K3`	`50000.0`
`I_max`	`20.0`
`fer`	`0.01`
`ngk`	`4.0`
`r`	`0.5`
`pleak`	`0.0002`
`gkATP_bar`	`2000.0`
`kPMCA`	`0.18`
`fatp`	`20.0`
`fcyt`	`0.01`
`glustep`	`0.0`
`nh`	`2.0`
`kSERCA`	`0.4`
`tau_I`	`10000.0`
`vCa`	`25.0`
`vK`	`-75.0`
`steptime`	`480000.0`
`fbt`	`20.0`
`Vgk`	`0.8`
`fmt`	`20.0`
`gluper`	`7.0`
`K4`	`1000.0`
`ffbp`	`0.2`
`glubasa1`	`7.0`
`autoadp`	`1.0`
`Kgk`	`7.0`
`Vglut`	`8.0`
`kg`	`0.1`
`K1`	`30.0`
`K2`	`1.0`
`adpknot`	`800.0`
`Kglut`	`7.0`
`delta`	`8.0`
`pfkbas`	`0.06`
`gkCa`	`400.0`
`ki`	`0.1`
`kappa`	`0.005`
`KD`	`0.5`
`gK`	`2700.0`
`alpha`	`4.5e-6`
`gCa`	`1000.0`
`r1`	`0.35`
`famp`	`0.02`
`cat`	`2.0`
`tau_a`	`300000.0`
`Atot`	`3000.0`
`sigmav`	`31.0`
`ky`	`2.2`
`gluamp`	`0.0`
`cm`	`5300.0`

States:

Name	Description
`G6P(time)`	`525.97`
`Gi(time)`	`6.0637`
`n(time)`	`0.00012`
`I(time)`	`0.316`
`FBP(time)`	`0.2088`
`v(time)`	`-66.7`
`Caer(time)`	`121.8`
`ADP(time)`	`537.6`
`Ca(time)`	`0.05626`

per_pixel_lighting — v0.0.1

Per Pixel Lighting

Details

perelson_kirschner_deboer_1993 — v0.0.1

Perelson 1993

Details

Parameters:

Name	Description
`N_AZT`	`1050.0`
`T_max`	`1500.0`
`T_0`	`1000.0`
`k_4`	`2.424`
`r`	`0.03`
`mu_V`	`2.4`
`tau`	`1096.0`
`N_initial`	`1400.0`
`k_3`	`0.023`
`mu_b`	`0.24`
`theta`	`1.0`
`mu_T`	`0.02`
`V_0`	`0.001`
`t_min`	`2.0`
`N`	`1000.0`
`k_2`	`0.003`
`gamma`	`2.0e-5`
`s`	`10.0`
`p`	`0.01`
`k_1`	`2.4e-5`

States:

Name	Description
`T_1(time)`	`0.0`
`T_2(time)`	`0.0`
`V(time)`	`0.001`
`T(time)`	`1000.0`

perelson_neumann_markowitz_leonard_ho_1996 — v0.0.1

Perelson, Neumann, Markowitz, Leonard, Ho, 1996

Details

Parameters:

Name	Description
`c`	`3.07`
`T`	`170000.0`
`N`	`774.0`
`k`	`2.4e-5`
`delta`	`0.49`

States:

Name	Description
`VNI(time)`	`0.0`
`VI(time)`	`216000.0`
`T_star(time)`	`0.0`

phillips_2007 — v0.0.1

Phillips 2007

Details

Parameters:

Name	Description
`tau_m`	`10.0`
`v_vc`	`-6.3`
`Qmax`	`100.0`
`Vao`	`1.0`
`mu`	`3.6`
`sigma`	`3.0`
`theta`	`10.0`
`tau_v`	`10.0`
`v_mv`	`-1.9`
`chi`	`10.8`
`v_vh`	`0.19`
`v_maQao`	`1.0`
`v_vm`	`-1.9`
`c0`	`1.0`

States:

Name	Description
`H(time)`	`15.0`
`Vv(time)`	`0.0`
`Vm(time)`	`0.0`

phillips_2008 — v0.0.1

Phillips 2008

Details

Parameters:

Name	Description
`tau_m`	`10.0`
`A`	`1.3`
`v_vc`	`-2.9`
`awake_start`	`167.04`
`Qmax`	`100.0`
`alpha`	`0.0`
`mu`	`4.4`
`sigma`	`3.0`
`theta`	`10.0`
`tau_v`	`10.0`
`v_mv`	`-1.8`
`chi`	`45.0`
`v_vh`	`1.0`
`awake_end`	`240.0`
`v_vm`	`-2.1`
`c0`	`4.5`

States:

Name	Description
`H(time)`	`15.0`
`Vv(time)`	`-12.5`
`Vm(time)`	`0.0`

pivonka_zimak_smith_gardiner_dunstan_sims_martin_mundy_2008 — v0.0.1

Pivonka, Zimak, Smith, Gardiner, Dunstan, Sims, Martin and Mundy, 2008

Details

Parameters:

Name	Description
`A_OC_a`	`0.7`
`KD_RANKL_activate`	`4.457`
`OC_a_initial`	`1.0`
`pd_OC_a`	`0.0`
`Deg_OPG`	`0.35`
`K_A1_RANKL`	`0.001`
`K_A2_RANKL`	`0.03412`
`D_OB_p`	`0.2674`
`KD_TGF_repress`	`0.001416`
`KD_TGF_activate`	`0.004545`
`k_res`	`200.0`
`RANK`	`10.0`
`KD_PTH_activate`	`0.2226`
`KD_PTH_repress`	`150.0`
`R2_OB_a_RANKL`	`0.0`
`Deg_RANKL`	`10.13`
`pd_OB_p`	`0.0`
`beta_RANKL`	`16840.0`
`beta2_OB_a_OPG`	`1.0`
`pd_OB_a`	`0.0`
`P_OPG_d`	`0.0`
`alpha`	`1.0`
`beta_PTH`	`250.0`
`P_PTH_d`	`0.0`
`Deg_PTH`	`86.0`
`k_form`	`1.571`
`D_OB_u`	`0.0007`
`OB_a_initial`	`1.0`
`R_RANKL`	`2.703e6`
`beta1_OB_p_OPG`	`0.0`
`R1_OB_p_RANKL`	`1.0`
`beta_OPG`	`1.625e8`
`A_OB_a`	`0.189`
`P_RANKL_d`	`0.0`
`OPG_max`	`2.0e8`

States:

Name	Description
`OB_p(time)`	`0.0006194`
`OB_a(time)`	`0.0005584`
`BV(time)`	`100.0`
`OC_a(time)`	`0.000807`

plant_1981 — v0.0.1

Plant, 1981

Details

Parameters:

Name	Description
`tau_xT`	`235.0`
`V_H_Na`	`115.0`
`K_c`	`0.0085`
`Kp`	`0.5`
`g_L`	`0.003`
`V_I`	`30.0`
`V_K`	`-75.0`
`V_L`	`-40.0`
`rho`	`0.0003`
`g_P`	`0.03`
`g_K`	`0.3`
`V_H_K`	`-12.0`
`V_Ca`	`140.0`

States:

Name	Description
`V(time)`	`-54.0`
`xT(time)`	`0.1`
`c(time)`	`0.1`
`xK(time)`	`0.1`
`yI(time)`	`0.1`

poh_2012 — v0.0.1

Poh, 2012

Details

Parameters:

Name	Description
`f_2`	`300.0`
`P_NCX`	`1992.335`
`Q10K`	`3.1`
`T`	`310.0`
`K_D_CaM`	`0.0001`
`Q10Na`	`2.45`
`n_CaM`	`4.0`
`Cao`	`2.0`
`g_NsK`	`0.017512`
`g_BK`	`80.0`
`CaM_total`	`0.012`
`t_ICCpeak`	`300.0`
`period`	`10000.0`
`g_Kv`	`1.0217`
`Ko`	`5.4`
`V_ICCamp`	`33.5`
`Cm`	`50.0`
`Q10Ca`	`2.1`
`t_slope`	`600.0`
`Nao`	`140.0`
`K_mK`	`1.0`
`K_mNai`	`87.5`
`g_Na`	`25.1`
`P_NaK`	`9.26`
`k_sat`	`0.1`
`Gcouple`	`2.6`
`t_ICCplateau`	`9700.0`
`V_ICCrest`	`-57.0`
`K_mNa`	`40.0`
`CRT_total`	`0.034`
`g_NsNa`	`0.022488`
`n_CRT`	`1.0`
`g_CaT`	`0.0425`
`f_1`	`12000.0`
`gamma`	`0.35`
`g_CaL`	`1.44`
`K_mCa`	`1.38`
`K_D_CRT`	`0.0009`
`R`	`8.314`
`F`	`96.48534`

States:

Name	Description
`IVf(time)`	`4.0998751301597e-6`
`x_Kv(time)`	`0.14714161078933`
`IVfCa(time)`	`8.84306615061238e-8`
`O_Na(time)`	`1.96760342050475e-6`
`C2(time)`	`0.0109545368437155`
`IVs(time)`	`1.1193313274705e-6`
`C0(time)`	`0.815464741971086`
`C2Ca(time)`	`0.000230369020877669`
`O2(time)`	`2.85143702125325e-8`
`C3Ca(time)`	`7.1754726923539e-6`
`C3(time)`	`0.973782548650071`
`IVsCa(time)`	`2.41429816075123e-8`
`I2(time)`	`0.00318975045717667`
`f_CaT(time)`	`0.377831534375835`
`O1(time)`	`5.55636826398253e-8`
`C4(time)`	`0.000759264410974374`
`Nai(time)`	`10.5731241425458`
`O_CaL(time)`	`3.88576045134351e-6`
`O3(time)`	`1.59832806123435e-6`
`C1Ca(time)`	`0.00328711668724504`
`V(time)`	`-73.5049651455872`
`d_CaT(time)`	`0.0791635737410974`
`C1(time)`	`0.0119443135223679`
`O4(time)`	`1.82113764497095e-6`
`C0Ca(time)`	`0.0175888495282545`
`Ki(time)`	`153.604280337996`
`y_Kv(time)`	`0.99994773314105`
`Cai(time)`	`5.38843941249284e-5`
`ICa(time)`	`8.38123983500905e-8`
`O0(time)`	`6.94960798375172e-7`
`I1(time)`	`0.000126882921013389`

potter_greller_cho_nuttall_stroup_suva_tobin_2005 — v0.0.1

Potter, Greller, Cho, Nuttall, Stroup, Suva, Tobin, 2005

Details

Parameters:

Name	Description
`kcl`	`0.005`
`De`	`0.0`
`dmin`	`0.0`
`k4_`	`0.4`
`j`	`9.0`
`k1`	`1.0e-6`
`k3_`	`0.0001`
`k2_`	`0.001`
`k4`	`0.002`
`Dd`	`0.015`
`k3`	`0.001`
`dmax`	`7.5`
`tau_on`	`0.5`
`tau_off`	`0.5`
`k1_`	`0.001`
`k2`	`1.0e-7`

States:

Name	Description
`P(time)`	`3.0`
`Ra(time)`	`16.9`
`Ci(time)`	`0.05`
`Ri(time)`	`1.7`
`Ca(time)`	`0.0004`

potter_zager_barton_2006 — v0.0.1

Potter, Zager, Barton, 2006

Details

Parameters:

Name	Description
`kDNA_offTTsec`	`2.4`
`kTR_on`	`0.14`
`kLH1`	`0.13`
`kDNA_onDDcd`	`0.14`
`kDNA_onTT5a`	`0.14`
`kTT_off`	`3.13`
`kDA_on`	`0.15`
`alpha_D`	`0.75`
`kTT_on`	`0.14`
`Ql`	`1.06`
`kcpl`	`1.17e-7`
`kcd1`	`0.014`
`kDT_off`	`3.13`
`kDNA_offDDsec`	`0.2`
`CTb`	`0.6275`
`kDNA_onDTsec`	`0.14`
`CDp`	`52.46`
`kDNA_onDT5a`	`0.14`
`kDNA_offTTcp`	`8.4`
`kDR_on`	`0.053`
`kLH4`	`0.8`
`kDNA_offDT5a`	`0.56`
`CTst`	`307.29`
`kLH2`	`0.026`
`VPL2`	`3.08e-6`
`k2T`	`0.17`
`alpha_T`	`0.25`
`kflo`	`0.043`
`k5a`	`3.02`
`VPC2`	`5.08e-5`
`CTp`	`11.38`
`CTif`	`307.29`
`PTst`	`1.0`
`k1R`	`68.15`
`CTl`	`9.92`
`kDA_off`	`5407.0`
`NDp`	`1.0`
`kQp`	`73.84`
`kDR_off`	`0.018`
`VPC1b`	`0.0001`
`kDNA_onDTcp`	`0.14`
`kLH3`	`0.000168`
`CTbl`	`7.6`
`kDNA_offDDcd`	`0.1`
`kDD_off`	`3.13`
`PTl`	`2.75`
`CDNAsec`	`0.075`
`Qc`	`6.08`
`kDNA_onDD5a`	`0.14`
`kDT_on`	`0.14`
`PDb`	`0.62`
`k1D`	`77.2`
`keR`	`71.9`
`kDNA_onTTcd`	`0.14`
`CA`	`500000.0`
`kDNA_offDDcp`	`0.7`
`kDNA_offDD5a`	`0.07`
`CDNA5a`	`0.075`
`CDNAcp`	`0.075`
`km5alpha`	`40.0`
`kDD_on`	`0.14`
`k1T`	`87.93`
`kTR_off`	`0.069`
`kTA_off`	`8131.0`
`kDNA_onDTcd`	`0.14`
`CDNAcd`	`0.075`
`kDNA_onDDcp`	`0.14`
`Qt`	`0.061`
`CDl`	`0.92`
`mu`	`1000.0`
`ts`	`0.56`
`kDNA_onTTsec`	`0.14`
`kDNA_onTTcp`	`0.14`
`kDNA_offDTcp`	`5.6`
`Vmax0`	`2.89`
`kDNA_offTT5a`	`0.84`
`CDbl`	`0.59`
`ksec`	`8.44e-6`
`PDl`	`2.0`
`PTif`	`1.96`
`NTp`	`0.79`
`PTb`	`1.0`
`kDNA_offDTcd`	`0.8`
`kDNA_onDDsec`	`0.14`
`CDb`	`0.019884`
`CLH`	`0.104`
`kDNA_offTTcd`	`1.2`
`kDNA_offDTsec`	`1.6`
`Vmax1`	`3.65`
`kTA_on`	`0.18`

States:

Name	Description
`CTTcp(time)`	`0.0`
`ATst(time)`	`0.0`
`ADbl(time)`	`0.0`
`CT_R(time)`	`0.0`
`VPC1(time)`	`0.0`
`ATb(time)`	`0.0`
`ATl(time)`	`0.0`
`CDD5a(time)`	`0.0`
`CDTsec(time)`	`0.0`
`CDD(time)`	`0.0`
`CTT(time)`	`0.0`
`CDTcd(time)`	`0.0`
`CDTcp(time)`	`0.0`
`CDT5a(time)`	`0.0`
`CT_A(time)`	`0.0`
`CDDsec(time)`	`0.0`
`CD_R(time)`	`0.0`
`AR(time)`	`0.0`
`ADb(time)`	`0.0`
`ATp(time)`	`0.0`
`ATbl(time)`	`0.0`
`VPL1(time)`	`0.0`
`CD_A(time)`	`0.0`
`CTTsec(time)`	`0.0`
`CTTcd(time)`	`0.0`
`ALH(time)`	`0.0`
`ATif(time)`	`0.0`
`CDDcp(time)`	`0.0`
`ADp(time)`	`0.0`
`CDT(time)`	`0.0`
`CTT5a(time)`	`0.0`
`CDDcd(time)`	`0.0`
`ADl(time)`	`0.0`

priebe_beuckelmann_1998 — v0.0.1

Priebe, Beuckelmann, 1998

Details

Parameters:

Name	Description
`preplength`	`100.0`
`T`	`310.15`
`Tn_max`	`0.07`
`failing`	`0.0`
`Km_Ca`	`0.0006`
`K_mup`	`0.00092`
`G_rel_max`	`22.0`
`stim_offset`	`0.0`
`delta_Ca_ith`	`5.0e-6`
`K_sat`	`0.1`
`Ko`	`4.0`
`Logicthresh`	`0.98`
`CMDN_max`	`0.05`
`V_step`	`0.0`
`Cm`	`153.4`
`V_clamp`	`0.0`
`K_mNa`	`87.5`
`eta`	`0.35`
`tau_tr`	`180.0`
`K_mCa`	`1.38`
`stim_duration`	`3.0`
`Cao`	`2.0`
`stim_period`	`1000.0`
`buffon`	`1.0`
`g_Ca_max`	`0.064`
`K_mCSQN`	`0.8`
`K_mCMDN`	`0.00238`
`radius`	`11.0`
`V_hold`	`-60.0`
`Nao`	`138.0`
`K_mNai`	`10.0`
`g_Na`	`16.0`
`G_rel_overload`	`3.0`
`stim_amplitude`	`-15.0`
`K_mrel`	`0.0008`
`CSQN_max`	`10.0`
`K_mTn`	`0.0005`
`g_Ks_max`	`0.02`
`K_mKo`	`1.5`
`CSQNthresh`	`0.7`
`R`	`8.3143`
`F`	`96.4867`
`g_Kr_max`	`0.015`

States:

Name	Description
`OVRLDtrack3(time)`	`1.0e-6`
`Ca_NSR(time)`	`2.5`
`OVRLDtrack2(time)`	`1.0e-6`
`t(time)`	`0.999897251531651`
`f(time)`	`0.92130376850548`
`Cainfluxtrack(time)`	`-7.71120176147331e-138`
`APtrack2(time)`	`-7.58517896402761e-136`
`j(time)`	`0.997011204496203`
`m(time)`	`0.000585525582501575`
`APtrack3(time)`	`4.82035353592764e-5`
`Nai(time)`	`10.0`
`APtrack(time)`	`-1.372158997089e-136`
`d(time)`	`2.50653215966786e-10`
`OVRLDtrack(time)`	`1.0e-6`
`V(time)`	`-90.7796417483135`
`h(time)`	`0.995865529216237`
`Xs(time)`	`0.00885658064818147`
`Ca_JSR(time)`	`2.5`
`Ki(time)`	`140.0`
`r(time)`	`1.75032478501027e-5`
`Cai(time)`	`0.0002`
`Xr(time)`	`0.000215523048438941`

proctor_2005 — v0.0.1

Proctor, 2005

Details

Mechanisms of aging and development

Parameters:

Name	Description
`k14`	`0.05`
`k21`	`1.0e-5`
`k20`	`0.1`
`k10`	`0.01`
`k9`	`1.0`
`k18`	`12.0`
`k13`	`0.5`
`k12`	`0.5`
`k15`	`0.08`
`k16`	`1000.0`
`k1`	`10.0`
`k8`	`500.0`
`k19`	`0.02`
`k4`	`1.0e-5`
`k3`	`50.0`
`k7`	`1.0e-7`
`k17`	`8.02e-9`
`k6`	`6.0e-7`
`k5`	`4.0e-6`
`k2`	`2.0e-5`
`k11`	`100.0`

States:

Name	Description
`HSE_TriH(time)`	`0.0`
`NatP(time)`	`6.0e6`
`ROS(time)`	`100.0`
`HCom(time)`	`5900.0`
`MCom(time)`	`0.0`
`ATP(time)`	`10000.0`
`AggP(time)`	`0.0`
`Hsp90(time)`	`300000.0`
`TriH(time)`	`0.0`
`MisP(time)`	`0.0`
`HSE(time)`	`1.0`
`DiH(time)`	`0.0`
`ADP(time)`	`1000.0`
`HSF1(time)`	`100.0`

proctor_2007 — v0.0.1

Proctor, 2007

Details

An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline

Parameters:

Name	Description
`k65`	`0.001`
`k69`	`0.0`
`k63`	`0.001`
`k72`	`1.0e-8`
`k61r`	`0.0002`
`k71`	`1.0e-8`
`k62`	`0.0002`
`k73`	`0.001`
`k66`	`1.0e-5`
`k1`	`0.01`
`k61`	`1.7e-5`
`k3`	`4.0e-6`
`k74`	`1.0e-5`
`k68`	`1.0e-5`
`k64`	`0.001`
`k2`	`2.0e-6`
`k67`	`1.0e-5`

States:

Name	Description
`MisP_Ub6(time)`	`0.0`
`MisP_Ub4(time)`	`0.0`
`Proteasome(time)`	`100.0`
`E3_MisP(time)`	`0.0`
`degUb5(time)`	`0.0`
`MisP_Ub7_Proteasome(time)`	`0.0`
`ROS(time)`	`10.0`
`AMP(time)`	`1000.0`
`E1(time)`	`100.0`
`ATP(time)`	`10000.0`
`MisP_Ub6_Proteasome(time)`	`0.0`
`degUb6(time)`	`0.0`
`MisP_Ub5(time)`	`0.0`
`degUb8(time)`	`0.0`
`SeqAggP(time)`	`0.0`
`MisP_Ub3(time)`	`0.0`
`E2_Ub(time)`	`0.0`
`ADP(time)`	`1000.0`
`NatP_refolded(time)`	`0.0`
`MisP_Ub5_Proteasome(time)`	`0.0`
`NatP(time)`	`500.0`
`E2(time)`	`100.0`
`Ub(time)`	`500.0`
`E1_Ub(time)`	`0.0`
`MisP_Ub7(time)`	`0.0`
`E3(time)`	`100.0`
`MisP_total(time)`	`0.0`
`AggP(time)`	`0.0`
`MisP_Ub(time)`	`0.0`
`MisP_Ub8_Proteasome(time)`	`0.0`
`MisP(time)`	`0.0`
`AggP_Proteasome(time)`	`0.0`
`degUb4(time)`	`0.0`
`MisP_Ub8(time)`	`0.0`
`degUb7(time)`	`0.0`
`MisP_Ub4_Proteasome(time)`	`0.0`
`DUB(time)`	`200.0`
`MisP_Ub2(time)`	`0.0`

puglisi_bers_2001 — v0.0.1

Puglisi, Bers, 2001

Details

Parameters:

Name	Description
`gamma_Cai`	`nothing`
`gamma_Cao`	`nothing`
`T`	`nothing`
`TRPN_max`	`nothing`
`C`	`nothing`
`P_Na`	`nothing`
`Km_Ca`	`nothing`
`g_Cl`	`nothing`
`delta_Ca_i2`	`nothing`
`K_mup`	`nothing`
`delta_Ca_ith`	`nothing`
`E_K`	`nothing`
`K_sat`	`nothing`
`delta_Ca_JSR`	`nothing`
`Y_to`	`nothing`
`gamma_Nao`	`nothing`
`tau_on`	`nothing`
`g_to`	`nothing`
`CMDN_max`	`nothing`
`V_NSR`	`nothing`
`E_Cl`	`nothing`
`R_A_V`	`nothing`
`P_NaK`	`nothing`
`K_mNa`	`nothing`
`eta`	`nothing`
`V_myo`	`nothing`
`I_stim`	`nothing`
`tau_tr`	`nothing`
`Ca_NSR_max`	`nothing`
`K_mCa`	`nothing`
`E_Na`	`nothing`
`Cao`	`nothing`
`X_to`	`nothing`
`g_Nab`	`nothing`
`K_mpCa`	`nothing`
`gamma_Nai`	`nothing`
`V_JSR`	`nothing`
`K_mCSQN`	`nothing`
`K_mCMDN`	`nothing`
`delta_Ca`	`nothing`
`gamma_Ki`	`nothing`
`t`	`nothing`
`tau_off`	`nothing`
`A_cap`	`nothing`
`I_pCa`	`nothing`
`I_NaK`	`nothing`
`Nao`	`nothing`
`K_mTRPN`	`nothing`
`K_mNai`	`nothing`
`P_Ca`	`nothing`
`g_Na`	`nothing`
`I_up`	`nothing`
`V_cleft`	`nothing`
`g_Cab`	`nothing`
`CSQN_th`	`nothing`
`g_Kp`	`nothing`
`K_mrel`	`nothing`
`CSQN_max`	`nothing`
`g_Ca_T`	`nothing`
`gamma_Ko`	`nothing`
`K_NaCa`	`nothing`
`K_mKo`	`nothing`
`R`	`nothing`
`P_K`	`nothing`
`F`	`nothing`

States:

Name	Description
`d(time)`	`nothing`
`g(time)`	`nothing`
`V(time)`	`nothing`
`h(time)`	`nothing`
`Ca_NSR(time)`	`nothing`
`f(time)`	`nothing`
`Xs(time)`	`nothing`
`Ko(time)`	`nothing`
`Ca_JSR(time)`	`nothing`
`Ki(time)`	`nothing`
`b(time)`	`nothing`
`j(time)`	`nothing`
`m(time)`	`nothing`
`Xr(time)`	`nothing`
`Nai(time)`	`nothing`
`Cai(time)`	`nothing`
`Ca_foot(time)`	`nothing`

purvis_butera_2005 — v0.0.1

Purvis, Butera, 2005

Details

Parameters:

Name	Description
`tau_m`	`5.0`
`tau_z`	`1.0`
`K2`	`0.04`
`E_Ca`	`40.0`
`i_stimAmplitude`	`10.0`
`C`	`0.04`
`theta_1`	`40.0`
`theta_h`	`70.0`
`sigma_h`	`3.0`
`sigma_1`	`5.0`
`theta_2`	`74.0`
`g_P`	`0.05`
`E_K`	`-80.0`
`g_N`	`0.05`
`sigma_2`	`7.5`
`i_stimStart`	`10.0`
`sigma_m`	`6.0`
`sigma_n`	`25.0`
`g_NaP`	`0.05`
`g_SK`	`0.3`
`tau_h`	`25.0`
`g_H`	`0.005`
`g_Na`	`0.7`
`theta_n`	`30.0`
`E_leak`	`-50.0`
`g_K`	`1.3`
`i_stimEnd`	`11.0`
`g_leak`	`0.005`
`g_T`	`0.1`
`E_H`	`-38.8`
`E_Na`	`60.0`
`theta_m`	`30.0`
`g_A`	`1.0`
`K1`	`-500.0`

States:

Name	Description
`V(time)`	`-71.847`
`h(time)`	`0.649`
`m(time)`	`0.001`
`n(time)`	`0.158`
`z(time)`	`0.0`
`Ca_conc(time)`	`0.0604`

purvis_smith_koizumi_butera_2007 — v0.0.1

Purvis, Smith, Koizumi, Butera, 2007

Details

Parameters:

Name	Description
`i_app`	`0.0`
`omega_m`	`-5.0`
`C`	`0.021`
`g_Na`	`28.0`
`theta_n`	`-29.0`
`omega_h`	`6.0`
`E_leak`	`-57.5`
`theta_h`	`-53.0`
`tau_h_max`	`10000.0`
`g_K`	`11.2`
`E_syn_e`	`0.0`
`E_K`	`-85.0`
`g_tonic_e`	`0.2`
`g_leak`	`2.2`
`tau_n_max`	`10.0`
`omega_n`	`-4.0`
`theta_m`	`-34.0`
`E_Na`	`50.0`
`g_NaP`	`1.5`

States:

Name	Description
`V(time)`	`-50.0`
`h(time)`	`0.92`
`n(time)`	`0.01`

Q

qu_maclellan_weiss_2003 — v0.0.1

Qu, Maclellan, Weiss, 2003

Details

Parameters:

Name	Description
`k2u`	`50.0`
`k14`	`1.0`
`bz`	`0.1`
`k10`	`10.0`
`k9`	`1.0`
`k13`	`1.0`
`bw`	`0.1`
`k15`	`1.0`
`aw`	`10.0`
`tau`	`25.0`
`k8`	`100.0`
`a`	`4.0`
`az`	`10.0`
`cz`	`1.0`
`ci`	`1.0`
`k4`	`30.0`
`k7u`	`0.0`
`k6`	`1.0`
`CDK_T`	`200.0`
`k11`	`1.0`
`k12`	`0.0`
`k16`	`2.0`
`k1`	`300.0`
`k16u`	`25.0`
`cw`	`1.0`
`k3`	`30.0`
`bi`	`0.1`
`k7`	`10.0`
`k5`	`0.1`
`ai`	`10.0`
`k2`	`5.0`

States:

Name	Description
`APC(time)`	`0.0`
`Cdc25(time)`	`0.0`
`wee1(time)`	`0.0`
`Cdc25_P(time)`	`0.0`
`CKI(time)`	`0.0`
`cyclin(time)`	`0.0`
`cyclin_CDK_CKI(time)`	`0.0`
`Cdc25_2P(time)`	`0.0`
`cyclin_CDK_inactive(time)`	`0.1`
`cyclin_CDK_CKI_P(time)`	`0.0`
`cyclin_CDK_active(time)`	`0.1`
`wee1_P(time)`	`0.0`

R

ralser_wamelink_kowald_gerisch_heeren_struys_klipp_jakobs_breitenbach_lehrach_krobitsch_2007 — v0.0.1

Ralser at el. 2007

Details

Parameters:

Name	Description
`KmG3PDHNAD`	`0.93`
`KmGLTGLCo`	`1.1918`
`KmGA3P`	`0.1`
`VmR5PIf`	`1039.0`
`KmADHACE`	`1.11`
`KmPGMP2G`	`0.08`
`GLY`	`0.15`
`VmDHAP`	`10900.0`
`VmPGI`	`339.677`
`CPFKAMP`	`0.0845`
`VmTransk1r`	`2.0`
`KmG3PDHDHAP`	`0.4`
`KmGLKADP`	`0.23`
`KmGAPDHBPG`	`0.0098`
`KmGAPDHNAD`	`0.09`
`KiNADPH`	`0.03`
`VmTransaldf`	`55.0`
`SUMAXP`	`4.1`
`KeqPGK`	`3200.0`
`VmTransk2f`	`3.2`
`VmTransaldr`	`10.0`
`cytoplasm`	`1.0`
`KmPFKF6P`	`0.1`
`CO2`	`1.0`
`KeqGLK`	`3800.0`
`KPFKAMP`	`0.0995`
`KmPYKATP`	`1.5`
`L0`	`0.66`
`VmGLK`	`226.452`
`KeqG3PDH`	`4300.0`
`VmG6PDH`	`4.0`
`KeqENO`	`6.7`
`VmTransk1f`	`4.0`
`KmENOP2G`	`0.04`
`KiADHNAD`	`0.92`
`KmPDCPYR`	`4.33`
`KmADHNADH`	`0.11`
`KmPFKATP`	`0.71`
`KmGluconate`	`0.02`
`VmGLT`	`97.264`
`VmGAPDHr`	`6549.68`
`KmEry4P`	`0.018`
`KmALDDHAP`	`2.4`
`KPFKF26BP`	`0.000682`
`KiPFKATP`	`0.65`
`Km6PGL`	`0.8`
`KmSeduhept`	`0.15`
`KmENOPEP`	`0.5`
`KmPYKADP`	`0.53`
`gR`	`5.12`
`VmPGK`	`1306.45`
`KeqALD`	`0.069`
`KmPGKBPG`	`0.003`
`CiPFKATP`	`100.0`
`ETOH`	`50.0`
`F26BP`	`0.02`
`KmPYKPYR`	`21.0`
`KmF6P`	`0.32`
`KmGLTGLCi`	`1.1918`
`VmPGM`	`2525.81`
`KmG3PDHGLY`	`1.0`
`VmG3PDH`	`70.15`
`KmPGKADP`	`0.2`
`KmXyl`	`1.5`
`Vm6PGL`	`4.0`
`KeqPYK`	`6500.0`
`KmG6P`	`0.04`
`KeqGLT`	`1.0`
`VmENO`	`365.806`
`KmDHAP`	`1.23`
`KeqTPI`	`0.045`
`KmRibo5P`	`1.6`
`kNADPH`	`2.0`
`VmPDC`	`174.194`
`KmRibose5P`	`0.1`
`KmRibu5P`	`1.6`
`SUCC`	`0.1`
`KmADHNAD`	`0.17`
`KmG3PDHNADH`	`0.023`
`KmALDGAP`	`2.0`
`VmADH`	`810.0`
`X`	`0.1`
`KeqPGI`	`0.314`
`KmGAPDHNADH`	`0.06`
`VmTransk2r`	`43.0`
`KeqADH`	`6.9e-5`
`VmPPIf`	`3458.0`
`VmPPIr`	`3458.0`
`KmPGIF6P`	`0.3`
`VmR5PIr`	`1039.0`
`CPFKF16BP`	`0.397`
`KiADHETOH`	`90.0`
`KATPASE`	`39.5`
`CPFKF26BP`	`0.0174`
`KeqPGM`	`0.19`
`KeqGAPDH`	`0.005`
`KSUCC`	`21.4`
`KmGLKGLCi`	`0.08`
`KmPYKPEP`	`0.14`
`KmADHETOH`	`17.0`
`KmNADP`	`0.03`
`KmPGIG6P`	`1.4`
`k_rel_TPI`	`1.0`
`nPDC`	`1.9`
`KiADHACE`	`1.1`
`VmPYK`	`1088.71`
`KmGLKG6P`	`30.0`
`VmPFK`	`182.903`
`KPFKF16BP`	`0.111`
`GLCo`	`50.0`
`KmGLKATP`	`0.15`
`KmPGKP3G`	`0.53`
`VmALD`	`322.258`
`KmPGMP3G`	`1.2`
`KmXyl5P`	`0.15`
`k_rel_GAPDH`	`1.0`
`KmPGKATP`	`0.3`
`KmALDF16P`	`0.3`
`KmALDGAPi`	`10.0`
`VmGAPDHf`	`1184.52`
`KiADHNADH`	`0.031`
`VmGluDH`	`4.0`
`VmGA3P`	`555.0`
`KeqAK`	`0.45`
`CPFKATP`	`3.0`
`KmGAPDHGAP`	`0.21`

States:

Name	Description
`P(time)`	`5.0`
`G6P(time)`	`1.39`
`PEP(time)`	`0.1`
`Ribulose5P(time)`	`0.1`
`Ribose5P(time)`	`0.1`
`P3G(time)`	`0.1`
`Xyl5P(time)`	`0.1`
`F6P(time)`	`0.28`
`D6PGluconate(time)`	`0.1`
`BPG(time)`	`0.1`
`GLCi(time)`	`0.087`
`Seduhept7P(time)`	`0.1`
`PYR(time)`	`3.36`
`GA3P(time)`	`0.05`
`NADPH(time)`	`1.6`
`F16P(time)`	`0.1`
`NADP(time)`	`0.4`
`NAD(time)`	`1.2`
`ACE(time)`	`0.04`
`DHAP(time)`	`1.0`
`D6PGluconoLactone(time)`	`0.1`
`Erythrose4P(time)`	`0.0`
`P2G(time)`	`0.1`
`NADH(time)`	`0.39`

ramirez_nattel_courtemanche_2000 — v0.0.1

Ramirez, Nattel, Courtemanche, 2000

Details

Parameters:

Name	Description
`Na_o`	`140.0`
`T`	`310.0`
`TRPN_max`	`0.35`
`K_up`	`0.00092`
`K_rel`	`30.0`
`Ca_up_max`	`15.0`
`Ca_o`	`1.8`
`g_B_Na`	`0.000674`
`g_Cl_Ca`	`0.3`
`V_rel`	`96.48`
`q_Ca`	`0.0`
`K_sat`	`0.1`
`i_NaK_max`	`0.6`
`K_o`	`5.4`
`I_up_max`	`0.005`
`V_i`	`13668.0`
`CMDN_max`	`0.045`
`g_Ca`	`0.24`
`Cm`	`100.0`
`g_to`	`0.19824`
`i_stim`	`-2900.0`
`Km_K_o`	`1.5`
`g_Na`	`7.8`
`g_B_Ca`	`0.00113`
`V_up`	`1109.52`
`K_mNa`	`87.5`
`i_p_Ca_max`	`0.275`
`g_Ks`	`0.0561`
`g_K1`	`0.15`
`CSQN_max`	`10.0`
`Cl_o`	`132.0`
`I_NaCa_max`	`1600.0`
`Km_Na_i`	`10.0`
`K_mCa`	`1.38`
`tau_tr`	`180.0`
`g_Kr`	`0.06984`
`R`	`8.3143`
`tau_f_Ca`	`2.0`
`F`	`96.4867`

States:

Name	Description
`Ca_CMDN(time)`	`0.001856`
`oa(time)`	`0.07164`
`oi(time)`	`0.998`
`Cl_i(time)`	`29.26`
`xr(time)`	`7.433e-7`
`v(time)`	`1.0`
`xs(time)`	`0.01791`
`f(time)`	`0.9999`
`ui(time)`	`0.9987`
`u(time)`	`0.0`
`j(time)`	`0.9869`
`m(time)`	`0.001972`
`Na_i(time)`	`11.75`
`w(time)`	`0.9993`
`d(time)`	`4.757e-6`
`Ca_rel(time)`	`1.502`
`V(time)`	`-83.53`
`h(time)`	`0.9791`
`ua(time)`	`0.05869`
`Ca_TRPN(time)`	`0.007022`
`K_i(time)`	`138.4`
`Ca_CSQN(time)`	`6.432`
`f_Ca(time)`	`0.7484`
`Ca_up(time)`	`1.502`
`Ca_i(time)`	`0.0001024`

rangamani_2007 — v0.0.1

Rangamani 2007

Details

Parameters:

Name	Description
`k20`	`0.0001`
`k21`	`0.0001`
`k10`	`1.25e-6`
`k9`	`0.000185`
`k18`	`0.0005`
`k_m1`	`1.0e6`
`k25`	`1.25e-6`
`k15`	`0.000185`
`k26`	`0.00037`
`k29`	`0.75`
`k8`	`1.25e-6`
`k19`	`0.0002`
`k4`	`1.25e-6`
`d_6`	`0.000283`
`k22`	`6.0e-5`
`k6`	`1.25e-6`
`k120`	`1.4e-5`
`k23`	`0.1`
`k110`	`0.00037`
`k16`	`1.25e-6`
`k_14`	`41.6`
`k130`	`1.25e-6`
`k1`	`0.000185`
`k140`	`0.00037`
`k3`	`0.000185`
`k28`	`0.0005`
`k7`	`0.000185`
`k17`	`0.00037`
`k5`	`0.000185`
`k24`	`0.000185`
`k2`	`1.25e-6`
`p`	`0.00175`

States:

Name	Description
`c20(time)`	`80.0`
`c13(time)`	`250.0`
`R_NOS2(time)`	`0.616`
`c18(time)`	`0.0`
`c22(time)`	`0.0`
`c27(time)`	`0.0`
`c2(time)`	`100.0`
`c5(time)`	`0.0`
`c23(time)`	`200.0`
`c4(time)`	`150.0`
`c21(time)`	`0.0`
`c15(time)`	`0.0`
`c30(time)`	`0.0`
`c19(time)`	`0.0`
`c9(time)`	`0.0`
`c16(time)`	`0.0`
`c1(time)`	`0.0`
`c31(time)`	`0.0`
`c12(time)`	`0.0`
`c8(time)`	`100.0`
`c17(time)`	`100.0`
`c10(time)`	`100.0`
`c29(time)`	`800.0`
`c7(time)`	`0.0`
`c14(time)`	`0.0`
`c24(time)`	`0.0`
`c28(time)`	`0.0`
`c6(time)`	`100.0`
`c25(time)`	`0.0`
`c26(time)`	`0.0`
`c3(time)`	`0.0`
`c11(time)`	`0.0`

raposo_sobrinho_ferreira_2002 — v0.0.1

Raposo, Sobrinho and Ferreira, 2002

Details

Parameters:

Name	Description
`X_R_i_D`	`90.0`
`k2_P`	`1.0`
`X_R_P_k_PTH`	`90.0`
`k_D`	`0.1`
`k_PTH`	`100.0`
`X_R_PTH_Ca`	`1.0`
`a`	`0.85`
`Y_PTH_p_2minus_Max`	`1.0`
`b_E_PTH`	`0.55`
`X_R_i_Ca`	`1.0`
`Y_Ca_i_2plus_Max`	`1.0`
`Y_PT_D_p_1plus_minus_Max`	`0.01`
`J_pu_P`	`1.27`
`C_Ca_p`	`2.4`
`k4_P`	`51.8`
`C_D_p`	`90.0`
`Stoic_Ca_P`	`0.464`
`J_P_ing`	`1.0`
`d`	`0.15`
`k_Ca_i`	`1.0`
`Y_k_Jext_1plus_minus_Max`	`0.01`
`C_Ca_i`	`1.0`
`C_PTH_p`	`3.85`
`b_PTH_Ca`	`0.05`
`b_i_D`	`0.03`
`k_Ca_b`	`1.0`
`Y_i_D_p_1plus_minus_Max`	`0.02`
`X_R_PTH_D`	`90.0`
`J_bp_Ca`	`3.3`
`X_R_E_PTH`	`3.85`
`C_P_p`	`1.2`
`k3_P`	`1.0`
`Y_PTH_p_2plus_Max`	`1.0`
`S_E`	`1.0`
`k_E`	`0.05`
`b_PTH_D`	`0.03`
`J_pu_Ca`	`0.21`
`Y_Ca_p_1plus_minus_Max`	`0.02`

States:

Name	Description
`Q_PTH_p(time)`	`1.0`
`Q_D_p(time)`	`1.0`
`Q_P_p(time)`	`1.0`
`Q_TP_k(time)`	`1.0`
`Q_E_k(time)`	`1.0`
`Q_C_PT(time)`	`1.0`
`Q_P_c(time)`	`3226.0`
`Q_P_b(time)`	`1.0`
`Q_Ca_b(time)`	`100.0`
`Q_Ca_p(time)`	`1.0`
`Q_TCa_i(time)`	`1.0`

rattananakul_lenbury_krishnamara_wollkind_2003 — v0.0.1

Rattananakul, Lenbury, Krishnamara, Wollkind, 2003

Details

Parameters:

Name	Description
`a3`	`0.675`
`kc`	`0.2`
`kp`	`0.5`
`a2`	`0.009`
`a1`	`0.05`
`b3`	`0.01`
`b2`	`0.3`
`k1`	`0.1`
`a4`	`0.01`
`delta`	`0.9`
`k3`	`0.025`
`epsilon`	`0.1`
`a5`	`0.005`
`k2`	`0.5`
`b1`	`0.1`

States:

Name	Description
`x(time)`	`2.0`
`y(time)`	`1.0`
`z(time)`	`0.15`

razumova_bukatina_campbell_1999 — v0.0.1

Razumova, Bukatina, Campbell, 1999

Details

Parameters:

Name	Description
`nu`	`3.0`
`h_prime_0`	`6.0`
`sigma_plus`	`8.0`
`e_cb`	`1.5`
`f_r`	`50.0`
`x_0`	`1.0e-16`
`g_0`	`4.0`
`R_T`	`1.0`
`k_off`	`50.0`
`sigma_minus`	`1.0`
`h_0`	`8.0`
`f_prime_0`	`400.0`
`k_on`	`120.0`

States:

Name	Description
`A_2(time)`	`0.005`
`SL(time)`	`2.0`
`A_1(time)`	`0.005`
`x_2(time)`	`1.0e-16`
`x_1(time)`	`1.0e-16`
`D(time)`	`0.005`

razumova_bukatina_campbell_2000 — v0.0.1

Razumova, Bukatina, Campbell, 2000

Details

Parameters:

Name	Description
`f_0`	`50.0`
`v`	`1.0`
`g`	`4.0`
`k_0_on`	`0.0`
`w`	`1.0`
`n_H`	`1.0`
`k_Ca_off`	`50.0`
`h`	`8.0`
`h_prime`	`6.0`
`R_T`	`1.0`
`u`	`1.0`
`f_prime_0`	`400.0`
`k_0_off`	`100.0`
`k_Ca_on`	`120.0`

States:

Name	Description
`A_2(time)`	`0.0`
`A_1(time)`	`0.0`
`D(time)`	`0.0`

reed_nijhout_sparks_ulrich_2004 — v0.0.1

Reed, Nijhout, Sparks, Ulrich, 2004

Details

Parameters:

Name	Description
`Km_five_mTHF_MS`	`25.0`
`alpha2`	`10.0`
`V_BHMTmax`	`2500.0`
`V_MATIIImax`	`22870.0`
`Km2_MATIII`	`21.1`
`Ki_GNMT`	`20.0`
`V_MATImax`	`561.0`
`alpha1`	`100.0`
`V_METHmax`	`4521.0`
`Km_GNMT`	`4500.0`
`V_GNMTmax`	`10600.0`
`Km_MATI`	`41.0`
`V_MSmax`	`500.0`
`Km_BHMT`	`12.0`
`beta2`	`30.0`
`Km_Hcy_MS`	`0.1`
`five_mTHF`	`5.2`
`Kd_MS`	`1.0`
`Km2_METH_A`	`10.0`
`Ki_MATI`	`50.0`
`beta1`	`1.7`

States:

Name	Description
`AdoHcy(time)`	`13.2`
`AdoMet(time)`	`137.6`
`Met(time)`	`53.5`
`Hcy(time)`	`0.88`

reidl_borowski_sensse_starke_zapotocky_eiswirth_2006 — v0.0.1

Reidl, Borowski, Sensse, Starke, Zapotocky, Eiswirth, 2006

Details

Parameters:

Name	Description
`CNG_tot`	`1.3e-13`
`km_CNG_i`	`0.34`
`k_Ca`	`1.0e-10`
`km_CNG_0`	`0.01`
`i_Ca`	`20000.0`
`kp_CaM4`	`1.1e9`
`CaM_tot`	`2.0e-5`
`sigma`	`5.0e-7`
`K_Ca`	`1.2e-7`
`kp_CNG_i`	`2.1e6`
`km_CaM4`	`2.5`

States:

Name	Description
`CNG_i(time)`	`0.0`
`CNG_o(time)`	`0.0`
`CaM4(time)`	`0.0`
`Ca(time)`	`0.0`

revilla_garcia-ramos_2003: revilla_garcia_ramos_2003 — v0.0.1

Revilla, Garcia-Ramos, 2003

Details

riccobene_omann_linderman_1999 — v0.0.1

Riccobene, Omann, Linderman, 1999

Details

Parameters:

Name	Description
`kf2`	`8.4e7`
`kr2`	`0.0046`
`ka`	`1.0e-7`
`kfR`	`10.0`
`alpha`	`10.0`
`Kact`	`0.0001`
`kds`	`0.0001`
`L`	`1.0e-12`
`kr`	`0.37`
`kf`	`8.4e7`
`ki`	`0.2`

States:

Name	Description
`LR(time)`	`0.01`
`R_star(time)`	`0.01`
`LR_star(time)`	`0.01`
`G(time)`	`0.01`
`R(time)`	`0.01`
`R_ds(time)`	`0.01`
`G_star(time)`	`0.01`
`LR_ds(time)`	`0.01`

rice_jafri_winslow_2000 — v0.0.1

Rice, Jafri, Winslow, 2000

Details

Parameters:

Name	Description
`g_`	`nothing`
`f`	`nothing`
`k_a_minus`	`nothing`
`f_XB`	`nothing`
`T`	`nothing`
`i_Ca_half`	`nothing`
`k_htrpn_plus`	`nothing`
`I_ns_Ca`	`nothing`
`Vmax_f`	`nothing`
`omega`	`nothing`
`k_b_minus`	`nothing`
`Ko`	`nothing`
`SL`	`nothing`
`Cm`	`nothing`
`k_htrpn_minus`	`nothing`
`V_NSR`	`nothing`
`g`	`nothing`
`k_sat`	`nothing`
`K_mNa`	`nothing`
`eta`	`nothing`
`zeta`	`nothing`
`PNa_K`	`nothing`
`LTRPN_tot`	`nothing`
`V_myo`	`nothing`
`k_b_plus`	`nothing`
`k_c_plus`	`nothing`
`tau_tr`	`nothing`
`k_c_minus`	`nothing`
`K_mCa`	`nothing`
`Pns_Na`	`nothing`
`g_XB`	`nothing`
`k_a_plus`	`nothing`
`N1`	`nothing`
`v1`	`nothing`
`b`	`nothing`
`Cao`	`nothing`
`V_SS`	`nothing`
`g_Nab`	`nothing`
`tau_xfer`	`nothing`
`K_mpCa`	`nothing`
`a`	`nothing`
`V_JSR`	`nothing`
`f_`	`nothing`
`k_trop_pn`	`nothing`
`K_mCSQN`	`nothing`
`n_fb`	`nothing`
`K_mCMDN`	`nothing`
`K_trop`	`nothing`
`K_m_ns_Ca`	`nothing`
`Vmax_r`	`nothing`
`A_cap`	`nothing`
`k_ltrpn_minus`	`nothing`
`CSQN_tot`	`nothing`
`I_NaK`	`nothing`
`k_rb`	`nothing`
`I_pCa`	`nothing`
`Nao`	`nothing`
`k_ltrpn_plus`	`nothing`
`K_mNai`	`nothing`
`CMDN_tot`	`nothing`
`k_fb`	`nothing`
`HTRPN_tot`	`nothing`
`P_Ca`	`nothing`
`g_Na`	`nothing`
`g_Cab`	`nothing`
`g_Kp`	`nothing`
`n_rb`	`nothing`
`m`	`nothing`
`Pns_K`	`nothing`
`k_NaCa`	`nothing`
`K_mKo`	`nothing`
`R`	`nothing`
`P_K`	`nothing`
`F`	`nothing`
`n`	`nothing`

States:

Name	Description
`P0(time)`	`nothing`
`P_C1(time)`	`nothing`
`X(time)`	`nothing`
`Ca_NSR(time)`	`nothing`
`P1(time)`	`nothing`
`P_C2(time)`	`nothing`
`C0(time)`	`nothing`
`C2(time)`	`nothing`
`y(time)`	`nothing`
`C3(time)`	`nothing`
`N0(time)`	`nothing`
`HTRPNCa(time)`	`nothing`
`O(time)`	`nothing`
`C_Ca0(time)`	`nothing`
`Ca_SS(time)`	`nothing`
`P2(time)`	`nothing`
`C_Ca3(time)`	`nothing`
`j(time)`	`nothing`
`C4(time)`	`nothing`
`m(time)`	`nothing`
`Nai(time)`	`nothing`
`LTRPNCa(time)`	`nothing`
`C_Ca4(time)`	`nothing`
`V(time)`	`nothing`
`h(time)`	`nothing`
`C_Ca1(time)`	`nothing`
`C1(time)`	`nothing`
`Ca_JSR(time)`	`nothing`
`Ki(time)`	`nothing`
`P_O1(time)`	`nothing`
`P3(time)`	`nothing`
`O_Ca(time)`	`nothing`
`Cai(time)`	`nothing`
`P_O2(time)`	`nothing`
`C_Ca2(time)`	`nothing`

rice_wang_bers_detombe_2008 — v0.0.1

Rice, Wang, Bers, Detombe, 2008

Details

Parameters:

Name	Description
`koffH`	`0.025`
`kn_p`	`0.5`
`Ca_amplitude`	`1.45`
`SEon`	`1.0`
`perm50`	`0.5`
`koffL`	`0.25`
`Ca_diastolic`	`0.09`
`hb`	`0.4`
`hfmdc`	`5.0`
`gslmod`	`6.0`
`hbmdc`	`0.0`
`tau1`	`20.0`
`fapp`	`0.5`
`massf`	`50.0`
`visc`	`3.0`
`len_hbare`	`0.1`
`Qgapp`	`2.5`
`len_thick`	`1.65`
`kp_n`	`0.05`
`SLmax`	`2.4`
`tau2`	`110.0`
`Qkn_p`	`1.6`
`kon`	`0.05`
`sigman`	`1.0`
`hf`	`2.0`
`KSE`	`1.0`
`SLrest`	`1.85`
`Qkon`	`1.5`
`Qkp_n`	`1.6`
`Qhf`	`6.25`
`PCon_t`	`0.002`
`start_time`	`5.0`
`PCon_c`	`0.02`
`SLset`	`1.9`
`sigmap`	`8.0`
`gapp`	`0.07`
`gxb`	`0.07`
`len_thin`	`1.2`
`Qkoff`	`1.3`
`PExp_c`	`70.0`
`SLmin`	`1.4`
`nperm`	`15.0`
`SL_c`	`2.25`
`TmpC`	`24.0`
`Qgxb`	`6.25`
`x_0`	`0.007`
`koffmod`	`1.0`
`Trop_conc`	`70.0`
`xPsi`	`2.0`
`Qhb`	`6.25`
`xbmodsp`	`1.0`
`Qfapp`	`6.25`
`PExp_t`	`10.0`
`kxb`	`120.0`

States:

Name	Description
`TRPNCaL(time)`	`0.0147730085063734`
`P_NoXB(time)`	`4.07437173988636e-8`
`TRPNCaH(time)`	`0.13066096561522`
`N(time)`	`0.999997834540066`
`SL(time)`	`1.89999811516093`
`xXBprer(time)`	`3.41212828972468e-8`
`XBprer(time)`	`3.0494964880038e-7`
`N_NoXB(time)`	`0.999999959256274`
`intf(time)`	`-4.5113452510363e-6`
`XBpostr(time)`	`1.81017564383744e-6`
`xXBpostr(time)`	`0.00700005394873882`

rice_winslow_hunter_1999 — v0.0.1

Rice, Winslow, Hunter, 1999

Details

Parameters:

Name	Description
`f`	`10.0`
`g`	`30.0`
`koff`	`40.0`
`alpha`	`1.0`
`koff_`	`19.6`
`K_Ca`	`1.47`
`SL`	`1.7`
`Ca`	`1.0`
`kon`	`20.0`
`k1_`	`45.0`
`g_`	`15.0`

States:

Name	Description
`P0(time)`	`nothing`
`TCa(time)`	`nothing`
`P3(time)`	`nothing`
`P2(time)`	`nothing`
`P1(time)`	`nothing`
`N1(time)`	`nothing`

rice_winslow_jafri_1999 — v0.0.1

Rice, Winslow, Jafri, 1999

Details

riemer_sobie_tung_1998 — v0.0.1

Riemer, Sobie, Tung, 1998

Details

Parameters:

Name	Description
`gamma_Cai`	`nothing`
`gamma_Cao`	`nothing`
`T`	`nothing`
`TRPN_max`	`nothing`
`calcium_overload`	`nothing`
`g_s`	`nothing`
`P_Na`	`nothing`
`Km_Ca`	`nothing`
`delta_Ca_i2`	`nothing`
`K_mup`	`nothing`
`Ca_JSR_old`	`nothing`
`delta_Ca_ith`	`nothing`
`K_sat`	`nothing`
`gamma_Nao`	`nothing`
`tau_on`	`nothing`
`CMDN_max`	`nothing`
`Cm`	`nothing`
`P_ns_Ca`	`nothing`
`R_A_V`	`nothing`
`P_NaK`	`nothing`
`K_mNa`	`nothing`
`eta`	`nothing`
`V_myo`	`nothing`
`tau_tr`	`nothing`
`Ca_NSR_max`	`nothing`
`K_mCa`	`nothing`
`Cao`	`nothing`
`g_Nab`	`nothing`
`K_mpCa`	`nothing`
`gamma_Nai`	`nothing`
`Cai_old`	`nothing`
`K_mCSQN`	`nothing`
`t`	`nothing`
`gamma_Ki`	`nothing`
`I_st`	`nothing`
`K_m_ns_Ca`	`nothing`
`K_mCMDN`	`nothing`
`tau_off`	`nothing`
`A_cap`	`nothing`
`E_s`	`nothing`
`I_pCa`	`nothing`
`I_NaK`	`nothing`
`Nao`	`nothing`
`K_mTRPN`	`nothing`
`K_mNai`	`nothing`
`P_Ca`	`nothing`
`g_Na`	`nothing`
`I_up`	`nothing`
`V_cleft`	`nothing`
`g_Cab`	`nothing`
`CSQN_th`	`nothing`
`g_Kp`	`nothing`
`K_mrel`	`nothing`
`CSQN_max`	`nothing`
`g_Ca_T`	`nothing`
`gamma_Ko`	`nothing`
`K_NaCa`	`nothing`
`K_mKo`	`nothing`
`R`	`nothing`
`P_K`	`nothing`
`F`	`nothing`

States:

Name	Description
`d(time)`	`nothing`
`g(time)`	`nothing`
`delta_Cai(time)`	`nothing`
`V(time)`	`nothing`
`h(time)`	`nothing`
`Ca_NSR(time)`	`nothing`
`c1(time)`	`nothing`
`f(time)`	`nothing`
`b1(time)`	`nothing`
`Xs(time)`	`nothing`
`Ko(time)`	`nothing`
`Ki(time)`	`nothing`
`b(time)`	`nothing`
`j(time)`	`nothing`
`Ca_total(time)`	`nothing`
`m(time)`	`nothing`
`Xr(time)`	`nothing`
`Nai(time)`	`nothing`
`Ca_foot(time)`	`nothing`

rivlin_saunders_1951 — v0.0.1

Rivlin, Saunders, 1951

Details

rogers_mcculloch_1994 — v0.0.1

Rogers, Mcculloch, 1994

Details

romond_rustici_gonze_goldbeter_1999 — v0.0.1

Romond, Rustici, Gonze, Goldbeter, 1999

Details

Parameters:

Name	Description
`v_i1`	`0.05`
`H_4`	`0.01`
`K_c2`	`0.5`
`v_d2`	`0.025`
`K_3`	`0.01`
`k_d2`	`0.001`
`H_3`	`0.01`
`U_2`	`0.15`
`U_4`	`0.05`
`H_1`	`0.01`
`K_4`	`0.01`
`K_im1`	`0.03`
`K_c1`	`0.5`
`K_2`	`0.01`
`V_4`	`0.05`
`V_2`	`0.15`
`K_d1`	`0.02`
`K_im2`	`0.03`
`U_M3`	`0.1`
`V_M1`	`0.3`
`k_d1`	`0.001`
`K_1`	`0.01`
`v_i2`	`0.05`
`H_2`	`0.01`
`V_M3`	`0.1`
`U_M1`	`0.3`
`K_d2`	`0.02`
`v_d1`	`0.025`

States:

Name	Description
`C_1(time)`	`2.0`
`M_2(time)`	`0.0`
`C_2(time)`	`0.0`
`X_2(time)`	`0.0`
`X_1(time)`	`0.0`
`M_1(time)`	`1.0`

rong_perelson_2009 — v0.0.1

Rong, Perelson 2009

Details

Parameters:

Name	Description
`c`	`23.0`
`k`	`2.4e-8`
`a_L`	`0.1`
`eta`	`0.001`
`a`	`0.03`
`delta`	`1.0`
`d_0`	`0.001`
`rho`	`0.01`
`N`	`2000.0`
`lambda`	`10000.0`
`T_off`	`54.0`
`d_T`	`0.01`
`T_on`	`50.0`
`p_v`	`2000.0`
`p`	`1.4`
`efficacy`	`0.85`

States:

Name	Description
`V(time)`	`50.0`
`T(time)`	`600000.0`
`L_a(time)`	`0.0`
`L_0(time)`	`2.0`
`L(time)`	`2.0`
`T_star(time)`	`0.3`

roux_noble_noble_marhl_2006 — v0.0.1

Roux, Noble, Noble, Marhl, 2006

Details

Parameters:

Name	Description
`V_surf`	`150.0`
`p`	`0.4`
`Clo`	`140.0`
`CaCT`	`0.0005`
`T`	`310.0`
`C`	`0.00012`
`i_pCamax`	`1.15`
`g_Cl`	`0.01`
`g_KCa`	`2.45`
`B`	`8.0e-5`
`Cli`	`55.0`
`tau_xi1`	`0.25`
`t36`	`1.5`
`Ko`	`5.0`
`cap`	`2.0e-5`
`x2`	`0.8`
`gamma_KSS`	`0.15`
`i_NaKmax`	`0.7`
`g_bCa`	`1.194e-5`
`Kmp_Ca`	`0.05`
`Km_nsCa`	`0.0012`
`g_Kdr`	`0.035`
`Km_Na`	`40.0`
`P_CaL`	`0.003`
`Cao`	`2.0`
`h`	`3.0`
`Ki`	`150.0`
`tau_xCa1`	`1.0`
`tau_xi2`	`1.98`
`A`	`0.0008`
`Nao`	`130.0`
`alpha`	`280.0`
`g_bK`	`0.008729`
`tau_f`	`0.0173`
`ds`	`30.0`
`Nai`	`12.0`
`beta`	`480.0`
`x1`	`15.0`
`g_bNa`	`0.003263`
`Km_K`	`1.0`
`R`	`8314.472`
`P_nsCa`	`1.75e-7`
`F`	`96485.3415`
`n`	`0.2`

States:

Name	Description
`d(time)`	`0.0`
`xi2(time)`	`0.0`
`xCa1(time)`	`1.0`
`V(time)`	`-60.0`
`xa(time)`	`0.001`
`ns(time)`	`1.0`
`f(time)`	`1.0`
`B(time)`	`0.001`
`xi1(time)`	`0.0`

rubin_shevtsova_ermentrout_smith_rybak_2009 — v0.0.1

Rubin, Shevtsova, Ermentrout, Smith and Rybak 2009

Details

Parameters:

Name	Description
`g_AD`	`10.0`
`C`	`0.02`
`c21`	`0.07`
`k_V2`	`4.0`
`a12`	`0.4`
`V_half`	`30.0`
`E_K`	`-85.0`
`g_synE`	`10.0`
`c11`	`0.115`
`b43`	`0.1`
`b42`	`0.35`
`c31`	`0.025`
`c34`	`0.0`
`b41`	`0.2`
`b23`	`0.25`
`c14`	`0.33`
`c12`	`0.3`
`g_K`	`5.0`
`c24`	`0.4`
`g_synI`	`60.0`
`b21`	`0.0`
`E_Na`	`50.0`
`k_AD3`	`1.3`
`E_synE`	`0.0`
`c33`	`0.0`
`k_AD4`	`0.9`
`k_V3`	`4.0`
`b31`	`0.3`
`d2`	`1.0`
`E_synI`	`-75.0`
`g_NaP`	`5.0`
`c13`	`0.63`
`E_L`	`-60.0`
`b34`	`0.35`
`b32`	`0.05`
`tau_AD3`	`2000.0`
`d1`	`1.0`
`b24`	`0.35`
`k_V1`	`8.0`
`k_AD2`	`0.9`
`tau_AD2`	`2000.0`
`g_L`	`2.8`
`tau_h_max`	`6000.0`
`c22`	`0.3`
`c23`	`0.0`
`d3`	`1.0`
`k_V4`	`4.0`
`tau_AD4`	`1000.0`
`c32`	`0.0`

States:

Name	Description
`V3(time)`	`-50.0`
`V2(time)`	`-50.0`
`V1(time)`	`-50.0`
`h(time)`	`0.92`
`V4(time)`	`-50.0`
`m(time)`	`0.92`

S

sachse_glanzel_seemann_2003 — v0.0.1

Sachse, Glanzel, Seemann, 2003

Details

sachse_moreno_abildskov_2008 — v0.0.1

Sachse, Moreno, Abildskov, 2008

Details

Parameters:

Name	Description
`k_a_minus`	`576.0`
`K_mEGTA`	`0.00015`
`stim_start`	`0.1`
`T`	`295.0`
`tau_Ca_inact`	`0.009`
`K_m_K`	`1.5`
`K_SR`	`1.0`
`kv0`	`30.0`
`Vmaxr`	`0.9`
`k_htrpn_plus`	`200000.0`
`k_o`	`18.0`
`d_NaCa`	`0.0001`
`k_b_minus`	`1930.0`
`aKir`	`0.94`
`Ko`	`5.0`
`i_NaK_max`	`0.08`
`number_of_fibroblasts`	`1.0`
`Cm`	`4.5e-6`
`k_htrpn_minus`	`0.066`
`g_B_K`	`0.000138`
`V_NSR`	`5.04e-6`
`k_v0`	`2.0`
`Eb`	`0.0`
`LTRPN_tot`	`0.07`
`V_myo`	`9.36e-6`
`EGTA_tot`	`10.0`
`g_K1`	`0.024`
`g_Ca_L`	`0.031`
`tau_tr`	`0.0005747`
`k_b_plus`	`4.05e9`
`k_c_plus`	`100.0`
`k_c_minus`	`0.8`
`LTRPNCa`	`0.0051619`
`i_Ca_P_max`	`0.004`
`GKir`	`0.001`
`k_a_plus`	`1.215e13`
`ko`	`77.0`
`Na_o`	`140.0`
`stim_duration`	`0.001`
`v1`	`1800.0`
`b`	`0.114`
`g_B_Na`	`8.015e-5`
`g_ss`	`0.007`
`V_SS`	`1.2e-8`
`Ca_o`	`1.2`
`tau_xfer`	`0.0267`
`a`	`0.886`
`Ki`	`140.0`
`V_JSR`	`5.6e-7`
`zv`	`1.28`
`R_mf`	`1.0e8`
`stim_end`	`10.0`
`bKir`	`1.26`
`stim_period`	`1.0`
`f_Na`	`0.2`
`K_mCSQN`	`0.8`
`K_mCMDN`	`0.00238`
`K_o`	`5.4`
`K_fb`	`0.000168`
`k_ltrpn_minus`	`40.0`
`CSQN_tot`	`15.0`
`K_m_Na`	`10.0`
`k_ltrpn_plus`	`40000.0`
`g_t`	`0.035`
`CMDN_tot`	`0.05`
`N_fb`	`1.2`
`HTRPN_tot`	`0.14`
`N_rb`	`1.0`
`Vmaxf`	`0.04`
`g_B_Ca`	`3.24e-5`
`g_f`	`0.00145`
`g_Na`	`0.8`
`PShkr`	`5.4e-9`
`stim_amplitude`	`0.1`
`K_rb`	`3.29`
`E_Ca_L`	`65.0`
`m`	`3.0`
`Gb`	`6.9e-6`
`gamma_NaCa`	`0.5`
`K_NaCa`	`9.984e-6`
`HTRPNCa`	`0.1394301`
`z_v`	`-1.53`
`R`	`8310.0`
`F`	`96500.0`
`n`	`4.0`

States:

Name	Description
`OShkrReal(time)`	`0.0`
`C4ShkrReal(time)`	`2.79e-7`
`P_C1(time)`	`0.6348229`
`Ca_ss(time)`	`8.737212e-5`
`Ca_NSR(time)`	`0.06600742`
`P_C2(time)`	`0.3647471`
`y(time)`	`0.003578708`
`s_slow(time)`	`0.6421196`
`f_11(time)`	`0.9999529`
`j(time)`	`0.6729362`
`C0ShkrReal(time)`	`0.911`
`m(time)`	`0.004164108`
`C2ShkrReal(time)`	`0.00302`
`s(time)`	`0.9842542`
`Na_i(time)`	`10.73519`
`d(time)`	`2.171081e-6`
`VmReal(time)`	`-58.0`
`V(time)`	`-80.50146`
`h(time)`	`0.6735613`
`r_ss(time)`	`0.002907171`
`f_12(time)`	`0.9999529`
`s_ss(time)`	`0.3142767`
`K_i(time)`	`139.2751`
`C3ShkrReal(time)`	`4.74e-5`
`Ca_JSR(time)`	`0.06607948`
`P_O1(time)`	`0.0004327548`
`r(time)`	`0.002191519`
`Ca_i(time)`	`7.901351e-5`
`P_O2(time)`	`6.06254e-10`
`Ca_inact(time)`	`0.9913102`
`C1ShkrReal(time)`	`0.0857`

saftenku_williams_sitsapesan_2001 — v0.0.1

Saftenku, Williams, Sitsapesan, 2001

Details

Parameters:

Name	Description
`C4O3`	`46.0`
`C3C2`	`8000.0`
`C1O2`	`2277.0`
`O2C3`	`92.0`
`O2O1`	`85.1`
`O3C4`	`300.0`
`C3O1`	`1100.0`
`C3O3`	`14.0`
`O2C1`	`2.62`
`O1O2`	`2.41`
`O1C3`	`3400.0`
`O3C3`	`138.0`
`O1C2`	`1480.0`
`C2O1`	`7.86`
`C2C1`	`13.3`
`O2C4`	`1900.0`
`C2C5`	`0.13`
`C2C3`	`68.0`
`C3O2`	`17.0`
`Ca`	`20.0`
`C1C2`	`2.5`
`C4O2`	`520.0`
`C5C2`	`3.6`

States:

Name	Description
`C5(time)`	`0.125`
`O3(time)`	`0.125`
`O1(time)`	`0.125`
`C4(time)`	`0.125`
`C2(time)`	`0.125`
`O2(time)`	`0.125`
`C1(time)`	`0.125`
`C3(time)`	`0.125`

sakmann_spindler_bryant_linz_noble_2000 — v0.0.1

Sakmann, Spindler, Bryant, Linz, Noble, 2000

Details

Parameters:

Name	Description
`proton`	`3.98e-5`
`stim_start`	`0.1`
`T`	`310.0`
`P_kna`	`0.03`
`alpha_Calmod`	`100000.0`
`g_bca`	`0.00025`
`alpha_Trop`	`100000.0`
`length`	`74.0`
`d_NaCa`	`0.0`
`K_leak_rate`	`0.05`
`alpha_up`	`0.4`
`i_NaK_max`	`0.7`
`Km_f2ds`	`0.001`
`g_to`	`0.005`
`delta_f`	`0.0001`
`Trop`	`0.05`
`Cm`	`0.000161`
`beta_up`	`0.03`
`FRiNaCa`	`0.001`
`FrICa`	`1.0`
`K_cyca`	`0.0003`
`beta_Trop`	`200.0`
`K_mNa`	`40.0`
`g_bna`	`0.0006`
`gnachannel`	`20.0`
`g_K1`	`0.2`
`delta_m`	`1.0e-5`
`P_Ca_L`	`0.11`
`K_srca`	`0.5`
`V_e_ratio`	`0.4`
`Na_o`	`140.0`
`V_ds_ratio`	`0.1`
`stim_duration`	`0.003`
`speed_d`	`3.0`
`Kdecay`	`10.0`
`K_m_rel`	`250.0`
`g_tos`	`0.0`
`n_NaCa`	`3.0`
`Ca_o`	`2.0`
`R_decay`	`20.0`
`nachanneldensity`	`1075.0`
`V_up_ratio`	`0.01`
`stim_period`	`1.0`
`stim_end`	`9.0`
`K_mk1`	`10.0`
`K_m_Ca_ds`	`0.01`
`Calmod`	`0.02`
`radius`	`12.0`
`beta_Calmod`	`50.0`
`K_o`	`4.0`
`K_m_Ca_cyt`	`0.0005`
`K_xcs`	`0.4`
`V_rel_ratio`	`0.1`
`P_CaK`	`0.002`
`K_mK`	`1.0`
`speed_f`	`0.3`
`g_pna`	`0.0029`
`stim_amplitude`	`-2.0`
`Km_f2`	`100000.0`
`P_CaNa`	`0.01`
`gamma`	`0.5`
`k_NaCa`	`0.00012`
`R`	`8314.472`
`F`	`96485.3415`

States:

Name	Description
`d(time)`	`0.000144`
`Ca_Trop(time)`	`0.0012852`
`Ca_rel(time)`	`0.7368094`
`xr(time)`	`1.98e-5`
`V(time)`	`-89.1374183`
`f2(time)`	`0.254433`
`xs(time)`	`0.0381477`
`h(time)`	`0.9873107`
`f(time)`	`0.9999993`
`K_i(time)`	`138.7963753`
`ProdFrac(time)`	`0.9584464`
`ActFrac(time)`	`0.0101647`
`Ca_ds(time)`	`0.0018991`
`r(time)`	`0.0`
`m(time)`	`0.0026891`
`Ca_up(time)`	`0.7625025`
`Ca_i(time)`	`5.44e-5`
`s(time)`	`0.7352365`
`f2ds(time)`	`0.9292189`
`Na_i(time)`	`5.6633707`
`Ca_Calmod(time)`	`0.0018544`

salem_saidel_stanley_cabrera_2002 — v0.0.1

Salem, Saidel, Stanley, Cabrera, 2002

Details

Parameters:

Name	Description
`aLA`	`1.8`
`RS0`	`0.111`
`ATP`	`4.5`
`NADH`	`0.19`
`aGL`	`4.0`
`sigmaCO2`	`1.0`
`aO2`	`6.53`
`Km`	`0.05`
`sigmaLA`	`0.51`
`aFA`	`0.5`
`sigmaO2`	`1.0`
`AF0`	`0.523`
`FC0`	`0.0088`
`Vmax`	`0.455`
`epsilon`	`0.775`
`CS0`	`1.0`
`PS0`	`0.2`
`sigmaFA`	`13.2`
`aCO2`	`15.5`
`sigmaGL`	`3.76`

States:

Name	Description
`GY(time)`	`33.0`
`FC(time)`	`0.0088`
`TG(time)`	`3.96`
`PC(time)`	`8.8`
`CO2(time)`	`20.0`
`O2(time)`	`0.963`
`CoA_pool(time)`	`0.043`
`GL(time)`	`0.998`
`GP(time)`	`0.171`
`NAD(time)`	`1.81`
`LA(time)`	`1.98`
`AC(time)`	`0.0046`
`PY(time)`	`0.2`
`FA(time)`	`0.021`
`ADP(time)`	`0.9`
`CR(time)`	`3.5`

SAN-ORd: SAN_ORd — v0.0.1

An encoding of the human ORd model by Steve Neiderer

Details

This workspace houses a CellML 1.0 encoding of the 2011 O'Hara, Virág, Varró, & Rudy 2011 human cardiac ventricular action potential model (ORd). The original article is available at http://www.ncbi.nlm.nih.gov/pubmed/21637795. This model was encoded based on the Matlab version of the code available from: http://rudylab.wustl.edu/research/cell/.

sarai_matsuoka_kuratomi_ono_noma_2003 — v0.0.1

Sarai, Matsuoka, Kuratomi, Ono, Noma, 2003

Details

Parameters:

Name	Description
`Y_d`	`0.027`
`g_ACh`	`4.32`
`k_C_U`	`0.143`
`P_lCa`	`0.44`
`T`	`310.0`
`P_Na`	`12.0`
`P_NaCa`	`6.81`
`KForceEC`	`140000.0`
`L`	`0.9602399999150041`
`P_ha_K`	`7.7286`
`V_rel`	`1.50795`
`Km_CaSR`	`0.08`
`Km_Ki`	`32.88`
`Km_Nai`	`8.75`
`B`	`1.2`
`k_C_CCa`	`6.954`
`k_CCa_UCa`	`0.0003`
`Ko`	`5.399964171929831`
`P_Cab`	`0.008`
`CMDN_max`	`0.05`
`P_KATP`	`0.0236`
`Cm`	`32.0`
`Z_2`	`0.0039`
`P_SR_T`	`11.58`
`k_AI_AP`	`8.75e-5`
`P_bNSC`	`0.152`
`P_NaK`	`21.0`
`P_st_K`	`0.138`
`h_c`	`0.005`
`Y_4`	`0.12`
`Y_1`	`39.0`
`k3`	`1.0`
`k_UCa_CCa`	`0.35`
`Z_1`	`0.03`
`ZeroForceEL`	`0.97`
`k_CCa_C`	`0.0042`
`Adenosine_Total`	`5.0`
`ProducingRate_Max`	`0.003`
`P_Kr`	`0.1045`
`Z_3`	`1560.0`
`ForceFactor`	`1.8e6`
`ACh`	`0.0`
`P_RyR`	`1860.0`
`Km_ATP`	`0.1`
`KForceLinearEc`	`200.0`
`P_CaL`	`2112.0`
`P_SR_L`	`13.77`
`Y_3`	`0.03`
`Cao`	`1.7999668787634697`
`k_U_UCa`	`6.954`
`Km_Cai`	`0.00138`
`Km_Ko`	`0.258`
`P_ha_Na`	`1.821`
`Km_Nao`	`87.5`
`Km_CaCyto`	`0.0008`
`k4`	`0.000849`
`N`	`1000.0`
`K_mCMDN`	`0.00238`
`K_mCSQN`	`0.8`
`L_a`	`1.17`
`Y_2`	`0.0039`
`Vi`	`2513.25`
`k_AP_AI`	`0.004`
`k_U_C`	`0.35`
`Nao`	`139.99977217549068`
`Km_Cao`	`1.38`
`Diadid_Factor`	`-3.0`
`Partition`	`0.32`
`V_up`	`3.769875`
`P_K1_0`	`0.003125`
`k1`	`0.01`
`Km_ACh`	`0.0042`
`P_st_Na`	`0.236`
`i_max`	`4875.0`
`CSQN_max`	`10.0`
`P_CaT`	`612.0`
`T_t`	`0.007`
`R`	`8.3143`
`k2`	`0.04`
`F`	`96.4867`

States:

Name	Description
`Caup(time)`	`3.539652240305415`
`y2(time)`	`0.6128486629679218`
`p_U(time)`	`0.018412749759150325`
`X(time)`	`0.9552449999150041`
`p_AP_CaL(time)`	`0.010773205742759775`
`p_open_RyR(time)`	`0.011424172905335395`
`p_close_RyR(time)`	`0.007354039651246729`
`y1(time)`	`0.04679297803939428`
`y(time)`	`0.54434573606543`
`O2(time)`	`1.1957124194086763e-8`
`Ca_Total(time)`	`5.185011336959393`
`C2(time)`	`3.757612529902994e-5`
`pCaCB(time)`	`0.02896443650702234`
`p_AI_Na(time)`	`0.9715915109181413`
`ATPi(time)`	`4.929308214702568`
`O1(time)`	`7.531035735927369e-7`
`y3(time)`	`0.6786243213825371`
`p_RP_CaL(time)`	`0.42833044151885075`
`Nai(time)`	`4.6808027298969925`
`p_AP_Na(time)`	`5.9898633533987405e-5`
`p_UCa(time)`	`0.00020870506374005444`
`pCB(time)`	`0.0020275353474589783`
`C1(time)`	`0.9999616586460943`
`p_RP_Na(time)`	`0.00022262336890623873`
`Ki(time)`	`139.22099524072777`
`p_C(time)`	`0.05040310692927668`
`Vm(time)`	`-42.987671350068005`
`p_AI_CaL(time)`	`0.5607106503080197`
`pCa(time)`	`0.24298053499618683`

sarkar_lauffenburger_2003 — v0.0.1

Sarkar, Lauffenburger, 2003

Details

saucerman_bers_2008 — v0.0.1

Saucerman, Bers, 2008

Details

Parameters:

Name	Description
`k20`	`10.0`
`kCaNCa_off`	`1.0`
`kCaN0_off`	`537.966`
`kbi`	`2.2`
`k2B_on`	`0.007`
`k4B_off`	`1.4e-5`
`k0B_on`	`0.007`
`kta`	`0.0022`
`kCaN4_off`	`0.0013`
`k4B_on`	`0.007`
`kb2i`	`328.36`
`kat`	`6.567`
`kib2`	`65.67`
`k0B_off`	`0.0014`
`Btot`	`24.5`
`kCaNCa_on`	`2.0`
`CaNtot`	`0.003`
`kib`	`6.567`
`kCaN2_off`	`3.2604`
`kSLCYT`	`8.59e-12`
`kPP1`	`1.72`
`k2B_off`	`1.4e-5`
`kCaN4_on`	`46.0`
`k20B`	`0.1`
`CaMKIItot`	`0.2`
`PP1tot`	`0.57`
`kat2`	`6.567`
`kCaN0_on`	`46.0`
`kt2a`	`32.835`
`k42`	`500.0`
`KmPP1`	`11.5`
`Ca`	`1.0`
`K`	`135.0`
`Mg`	`1.0`
`kCaN2_on`	`46.0`

States:

Name	Description
`CaMCaN(time)`	`0.1`
`Pa(time)`	`0.1`
`Ca2CaMB(time)`	`0.1`
`Ca4CaM(time)`	`0.1`
`Pb2(time)`	`0.1`
`Pb(time)`	`0.1`
`CaMB(time)`	`0.1`
`CaM(time)`	`0.1`
`Ca2CaM(time)`	`0.1`
`Pt(time)`	`0.1`
`Ca4CaN(time)`	`0.1`
`Pt2(time)`	`0.1`
`Ca2CaMCaN(time)`	`0.1`
`Ca4CaMCaN(time)`	`0.1`
`Ca4CaMB(time)`	`0.1`

saucerman_brunton_michailova_mcculloch_2003 — v0.0.1

Saucerman, Brunton, Michailova, Mcculloch, 2003

Details

saucerman_mcculloch_2004 — v0.0.1

Saucerman, Mcculloch, 2004

Details

Parameters:

Name	Description
`PKACII_RyRtot`	`0.034`
`RyRsum`	`0.135`
`KMrel0`	`1.0`
`Ks_RyR_PP2A`	`4.1`
`kPKA_TnI`	`54.0`
`KMTnC0`	`1.0`
`PP1_RyRtot`	`0.034`
`kPKA_RyR`	`54.0`
`PP2A`	`1.0`
`PKAC`	`1.0`
`Ks_RyR_PP1`	`7.0`
`kPP1_RyR`	`8.52`
`kPP2A_TnI`	`10.1`
`Ks_RyR_PKAC`	`21.0`
`KM_PP2A_TnI`	`3.0`
`epsilon`	`10.0`
`KM_PKA_TnI`	`21.0`
`PP2A_RyRtot`	`0.034`
`kPP2A_RyR`	`10.1`
`TnItot`	`70.0`

States:

Name	Description
`TnIp(time)`	`nothing`
`RyR(time)`	`nothing`
`RyRptot(time)`	`nothing`
`PP2A_RyR(time)`	`nothing`
`PP1_RyR(time)`	`nothing`
`RyRp(time)`	`nothing`
`PKACII_RyR(time)`	`nothing`

schenzle_1994 — v0.0.1

Schenzle 1994

Details

Parameters:

Name	Description
`X0`	`1.0e11`
`alpha`	`1.0e-6`
`b`	`0.2`
`mu2`	`1.0`
`mu0`	`0.004`
`a`	`1000.0`
`beta`	`0.5`
`delta1`	`0.3`
`omega`	`1.6e-16`
`phi`	`1000.0`
`gamma`	`0.5`
`delta2`	`1.0`
`mu1`	`0.3`

States:

Name	Description
`Z(time)`	`0.0`
`K(time)`	`1.35e-14`
`V(time)`	`1000.0`
`X(time)`	`1.0e11`
`Y(time)`	`100.0`

schlosser_selgrade_2000 — v0.0.1

Schlosser, Selgrade, 2000

Details

Parameters:

Name	Description
`Ki_LHP`	`26.0`
`kLH_rel`	`3.0`
`V0_LH`	`1400.0`
`dP`	`2.9`
`Ki_FSH_Ih`	`1176.5`
`CFSH_P`	`3.0`
`kFSH_cl`	`8.21`
`CLH_P`	`0.024`
`dE`	`0.42`
`h`	`8.0`
`kFSH_rel`	`45.0`
`Km_LH`	`360.0`
`V_FSH`	`4400.0`
`V1_LH`	`95900.0`
`CFSH_E`	`0.005`
`CLH_E`	`0.008`
`kLH_cl`	`14.0`
`v_dis`	`2.5`
`dIh`	`2.0`

States:

Name	Description
`FSH(time)`	`150.0`
`RP_FSH(time)`	`0.0`
`LH(time)`	`40.0`
`RP_LH(time)`	`467.0`

schmid_nash_young_hunter_2006 — v0.0.1

Schmid, Nash, Young, Hunter, 2006

Details

schmitmeier_2007 — v0.0.1

Improvement of metabolic performance of primary hepatocytes in hyperoxic cultures by vitamin C in a novel small-scale bioreactor

Details

Our small-scale bioreactor with a gas-permeable membrane has previously been shown to allow direct oxygenation of primary hepatocytes in collagenous sandwich cultures. In this work the applicability of this system for studying the response of hepatocytes to different ambient oxygen concentrations above the normoxic situation and the effect of the antioxidant vitamin C (ASC) on hepatocyte functionality in different oxygen cultures were evaluated. Determination of the parameters for functional levels (albumin and urea synthesis, biotransformation) combined with the model calculation of these parameters using a product inhibition model based on the concentration of hydrogen peroxide (H2 O2 ) indicated a relevance of oxygen levels for the maintenance of hepatic-specific functions. A model for the dynamics of oxidative stress was proposed to predict the time course of the qualitative concentrations of H2 O2 and the superoxide radical (O2.- ) in different oxygen cultures. The 20% and 30% O2 cultures exhibited similar differentiated hepatic functions that were unequivocally lost in the 40% O2 cultures apparently due to oxidative damage. Metabolic functions in the 20% and 30% O2 cultures could be improved by ASC. These findings suggest that our bioreactor model not only allows a prediction of the liver response to variations in oxygen environments, but also serves as an in vitro tool to screen new compounds for antioxidant capacity.

Parameters:

Name	Description
`p4`	`8.379310334`
`Vmax`	`1.04e7`
`p3`	`2.552293418`
`ki`	`8.982e-6`
`p2`	`0.117425199`
`F1`	`20.0`
`p1`	`1.43385e-5`

States:

Name	Description
`H2O2(time)`	`2.7947e-5`
`O2(time)`	`0.00235897`

schneider_shimayoshi_amano_matsuda_2006 — v0.0.1

Schneider, Shimayoshi, Amano, Matsuda, 2006

Details

Parameters:

Name	Description
`RU_total`	`0.0726`
`k_tmxb`	`-1.86`
`k_5`	`0.03723`
`k_4`	`0.077`
`k_minus3`	`0.008`
`k_minus4`	`0.001`
`k_Titin`	`0.2`
`MADPPi`	`0.1375`
`k_tmoff`	`0.067`
`k_3xb`	`-1.23`
`k_tmRU`	`10.0`
`k_3c`	`0.025`
`k_minus12`	`0.6`
`k_on`	`17.3`
`k_12`	`2.0`
`k_tmonc`	`0.014`
`L_0`	`0.001`
`k_xboff`	`-1.37`
`k_3f`	`50.0`
`k_offi`	`0.075`
`A_iso`	`9000.0`
`k_onI`	`0.2`
`k_off`	`0.2`
`k_OFF`	`-0.32`

States:

Name	Description
`RUA_MADPPi(time)`	`0.0`
`RUTCa_off(time)`	`0.0`
`RUTCa_on(time)`	`0.0`
`RUAMADPPi(time)`	`0.0`
`RUA_MADP(time)`	`0.0`
`RUTM_on(time)`	`0.0`
`Ca(time)`	`0.01`

schoeberl_eichlerjonsson_gilles_muller_2002 — v0.0.1

Schoeberl, Eichler-Jonsson, Gilles, Muller, 2002

Details

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

Parameters:

Name	Description
`k34`	`1.8`
`kd24`	`33.0`
`k18`	`0.0015`
`kd23`	`36.0`
`k40`	`0.003`
`k25`	`0.001`
`k52`	`0.00534`
`kd3`	`0.6`
`kd35`	`0.00045`
`kd8`	`12.0`
`k29`	`60.0`
`kd25`	`1.284`
`k8`	`0.0001`
`Vm36`	`61200.0`
`k49`	`3.48`
`kd32`	`2.4e-5`
`k61`	`0.01002`
`kd44`	`1.0998`
`kd52`	`1.98`
`kd34`	`0.00045`
`kd22`	`6.0`
`Km36`	`2.0e14`
`kd2`	`6.0`
`k37`	`18.0`
`k56`	`0.00145`
`k53`	`960.0`
`k60`	`0.04002`
`k16`	`0.001`
`kd56`	`36.0`
`k43`	`60.0`
`k32`	`6.0`
`k41`	`0.003`
`k33`	`12.0`
`k3`	`60.0`
`kd50`	`30.0`
`k28`	`0.0001`
`k42`	`0.007`
`k17`	`0.001`
`kd6`	`0.3`
`kd42`	`12.0`
`k20`	`0.00021`
`kd4`	`0.0996`
`k21`	`1.38`
`RT`	`50000.0`
`k13`	`130.2`
`k58`	`0.0005`
`k47`	`174.0`
`k15`	`600000.0`
`k35`	`0.09`
`k45`	`210.0`
`k19`	`30.0`
`k57`	`16.2`
`k4`	`1.038e-5`
`kd16`	`16.5`
`k22`	`0.0021`
`kd21`	`2.2e-5`
`kd28`	`0.318`
`k6`	`0.003`
`kd40`	`3.84`
`kd29`	`7.0e-5`
`kd20`	`24.0`
`kd10`	`0.66`
`kd1`	`0.228`
`k44`	`0.00111`
`k23`	`360.0`
`kd33`	`0.0021`
`k1`	`0.003`
`kd41`	`2.574`
`k10b`	`3.25581`
`kd37`	`9.0e-5`
`kd17`	`3.6`
`kd19`	`1.0e-5`
`kd58`	`30.0`
`kd18`	`78.0`
`k50`	`2.5e-5`
`k48`	`0.00143`
`k55`	`342.0`
`k59`	`18.0`
`k2`	`0.001`
`kd48`	`48.0`

States:

Name	Description
`c20(time)`	`0.0`
`c26(time)`	`72000.0`
`c33(time)`	`0.0`
`c79(time)`	`0.0`
`c86(time)`	`0.0`
`c13(time)`	`0.0`
`c18(time)`	`0.0`
`c52(time)`	`0.0`
`c72(time)`	`0.0`
`c2(time)`	`50000.0`
`c55(time)`	`2.1e7`
`c81(time)`	`0.0`
`c23(time)`	`0.0`
`c53(time)`	`40000.0`
`c69(time)`	`0.0`
`c42(time)`	`0.0`
`c56(time)`	`0.0`
`c36(time)`	`0.0`
`c16(time)`	`0.0`
`c75(time)`	`0.0`
`c10(time)`	`0.0`
`c28(time)`	`0.0`
`c54(time)`	`0.0`
`c48(time)`	`0.0`
`c3(time)`	`0.0`
`c11(time)`	`0.0`
`c62(time)`	`0.0`
`c73(time)`	`0.0`
`c88(time)`	`0.0`
`c67(time)`	`0.0`
`c66(time)`	`0.0`
`c64(time)`	`0.0`
`c77(time)`	`0.0`
`c76(time)`	`0.0`
`c45(time)`	`0.0`
`c89(time)`	`0.0`
`c21(time)`	`0.0`
`c74(time)`	`0.0`
`c71(time)`	`0.0`
`c51(time)`	`0.0`
`c85(time)`	`0.0`
`c32(time)`	`0.0`
`c47(time)`	`2.2e7`
`c1(time)`	`4962.0`
`c38(time)`	`0.0`
`c40(time)`	`0.0`
`c29(time)`	`0.0`
`c68(time)`	`0.0`
`c91(time)`	`0.0`
`c24(time)`	`26300.0`
`c43(time)`	`0.0`
`c80(time)`	`0.0`
`c35(time)`	`0.0`
`c58(time)`	`0.0`
`c27(time)`	`0.0`
`c22(time)`	`11000.0`
`c44(time)`	`40000.0`
`c65(time)`	`0.0`
`c4(time)`	`0.0`
`c41(time)`	`40000.0`
`c15(time)`	`0.0`
`c84(time)`	`0.0`
`c59(time)`	`0.0`
`c30(time)`	`40000.0`
`c90(time)`	`0.0`
`c9(time)`	`0.0`
`c39(time)`	`0.0`
`c31(time)`	`101000.0`
`c63(time)`	`0.0`
`c12(time)`	`81000.0`
`c8(time)`	`0.0`
`c70(time)`	`0.0`
`c14(time)`	`12000.0`
`c7(time)`	`0.0`
`c34(time)`	`0.0`
`c93(time)`	`0.0`
`c83(time)`	`0.0`
`c5(time)`	`0.0`
`c61(time)`	`0.0`
`c94(time)`	`0.0`
`c78(time)`	`0.0`
`c92(time)`	`0.0`
`c19(time)`	`0.0`
`c57(time)`	`0.0`
`c17(time)`	`0.0`
`c82(time)`	`0.0`
`c87(time)`	`0.0`
`c46(time)`	`0.0`
`c37(time)`	`0.0`
`c25(time)`	`0.0`
`c60(time)`	`1.0e7`
`c49(time)`	`0.0`
`c6(time)`	`0.0`
`c50(time)`	`0.0`

schuster_beny_meister_2003 — v0.0.1

Schuster, Beny, Meister, 2003

Details

Parameters:

Name	Description
`m3cat`	`-6.18`
`GR`	`955.0`
`c`	`-6.4`
`C`	`1.0`
`b`	`-80.8`
`Vrest`	`-31.1`
`a`	`53.3`
`E_K`	`-80.0`
`kPMCA`	`0.679`
`ECa`	`50.0`
`m4`	`0.3`
`m4PMCA`	`0.39`
`m4cat`	`0.37`
`A`	`0.211`
`kSR_rel`	`180.0`
`Gcat`	`0.66`
`m3SR`	`1.1`
`PoSKCa`	`0.5`
`m3IP3`	`4.0`
`m4IP3`	`55.0`
`Gtot`	`6927.0`
`m3`	`0.00132`
`kIP3`	`0.1733`
`m4SR`	`0.3`
`m3PMCA`	`-6.19`

States:

Name	Description
`Vm(time)`	`-31.1`
`IP3(time)`	`1.0`
`Ca(time)`	`50.0`

sedaghat_sherman_quon_2002 — v0.0.1

Sedaghat, Sherman, Quon, 2002

Details

Parameters:

Name	Description
`k_minus5`	`1.67e-18`
`k4b`	`0.0021`
`k_minus14`	`0.001155`
`PTEN`	`1.0`
`K_d`	`12.0`
`tau`	`1.5`
`k_minus4`	`0.003`
`k_minus13`	`0.167`
`APequil`	`9.09`
`k6`	`0.461`
`k9_stimulated`	`1.39`
`PI3K`	`5.0e-15`
`k_minus10`	`2.77`
`k_minus4b`	`0.00021`
`PTP`	`1.0`
`k1`	`6.0e7`
`k_minus1`	`0.2`
`SHIP`	`1.0`
`IRp`	`8.97e-13`
`k3`	`2500.0`
`V_max`	`20.0`
`k_minus8`	`10.0`
`k7`	`4.16`
`n`	`4.0`

States:

Name	Description
`x10(time)`	`0.0`
`x17(time)`	`0.0`
`x9(time)`	`1.0e-12`
`x5(time)`	`0.0`
`x18(time)`	`100.0`
`x16(time)`	`100.0`
`x2(time)`	`9.0e-13`
`x4(time)`	`0.0`
`x6(time)`	`1.0e-13`
`x3(time)`	`0.0`
`x21(time)`	`4.0`
`x7(time)`	`0.0`
`x20(time)`	`96.0`
`x19(time)`	`0.0`
`x13(time)`	`0.31`
`x10a(time)`	`0.0`
`x8(time)`	`0.0`
`x12(time)`	`2.54e-15`
`x14(time)`	`99.4`
`x15(time)`	`0.29`
`x11(time)`	`1.0e-13`

seemann_sachse_weib_dossel_2003 — v0.0.1

Seemann, Sachse, Weib, Dossel, 2003

Details

severi_fantini_charawi_difrancesco_2012 — v0.0.1

Details

Parameters:

Name	Description
`K3ni`	`26.44`
`T`	`6.928`
`C`	`3.2e-5`
`Km_fCa`	`0.00035`
`TC_tot`	`0.031`
`Km_Kp`	`1.4`
`kf_TC`	`88800.0`
`Iva_3_uM`	`0.0`
`Km_Nap`	`14.0`
`kbBAPTA`	`119.38`
`K1ni`	`395.3`
`EC50_SR`	`0.45`
`i_NaK_max`	`0.063`
`Ko`	`5.4`
`MaxSR`	`15.0`
`Kcni`	`26.44`
`L_sub`	`0.02`
`g_to`	`0.002`
`alpha_fCa`	`0.01`
`t_test`	`0.5`
`t_holding`	`0.5`
`BAPTA_10_mM`	`0.0`
`kb_TC`	`446.0`
`Qco`	`0.0`
`V_nsr_part`	`0.0116`
`P_up_basal`	`12.0`
`kf_TMM`	`2277.0`
`V_holding`	`-45.0`
`kfBAPTA`	`940000.0`
`Kco`	`3.663`
`clamp_mode`	`0.0`
`TMC_tot`	`0.062`
`kf_CM`	`227700.0`
`delta_m`	`1.0e-5`
`kim`	`5.0`
`tau_tr`	`0.04`
`g_Kr`	`0.0021637`
`kf_CQ`	`534.0`
`V_i_part`	`0.46`
`Kc`	`5.4`
`ACh`	`0.0`
`P_CaL`	`0.2`
`CQ_tot`	`10.0`
`K1no`	`1628.0`
`K_up`	`0.0006`
`kb_CM`	`542.0`
`Cao`	`1.8`
`shift`	`0.0`
`Km_f`	`45.0`
`Mgi`	`2.5`
`K2no`	`561.4`
`Ki`	`140.0`
`Qn`	`0.4315`
`tau_dif_Ca`	`4.0e-5`
`kb_TMM`	`751.0`
`koCa`	`10000.0`
`K3no`	`4.663`
`kom`	`60.0`
`K2ni`	`2.289`
`kf_TMC`	`227700.0`
`MinSR`	`1.0`
`ks`	`2.5e8`
`kb_CQ`	`445.0`
`Qci`	`0.1369`
`Nao`	`140.0`
`HSR`	`2.5`
`kiCa`	`500.0`
`Kci`	`0.0207`
`g_Na`	`0.0125`
`kb_TMC`	`7.51`
`g_KACh`	`0.00864`
`Cs_5_mM`	`0.0`
`V_jsr_part`	`0.0012`
`L_cell`	`70.0`
`P_CaT`	`0.02`
`R_cell`	`4.0`
`CM_tot`	`0.045`
`K_NaCa`	`4.0`
`V_test`	`-35.0`
`R`	`8314.472`
`F`	`96485.3415`
`Iso_1_uM`	`0.0`

States:

Name	Description
`paS(time)`	`0.322999177802891`
`paF(time)`	`0.0990510403258968`
`V_ode(time)`	`-52.0`
`dT(time)`	`0.0`
`I(time)`	`7.86181717518e-8`
`piy(time)`	`0.705410877258545`
`y(time)`	`0.181334538702451`
`fT(time)`	`0.0`
`fCQ(time)`	`0.299624275428735`
`O(time)`	`1.7340201253e-7`
`Ca_nsr(time)`	`1.05386465080816`
`fTC(time)`	`0.0180519400676086`
`Ca_sub(time)`	`1.0e-5`
`fCMs(time)`	`0.054381370046`
`n(time)`	`0.0`
`fTMC(time)`	`0.281244308217086`
`m(time)`	`0.440131579215766`
`q(time)`	`0.506139850982478`
`Ca_jsr(time)`	`0.316762674605`
`RI(time)`	`0.211148145512825`
`fBAPTA(time)`	`0.0`
`Nai_(time)`	`7.5`
`fTMM(time)`	`0.501049376634`
`h(time)`	`1.3676940140066e-5`
`fBAPTA_sub(time)`	`0.0`
`a(time)`	`0.0`
`fCa(time)`	`0.697998543259722`
`fCMi(time)`	`0.0373817991524254`
`r(time)`	`0.0144605370597924`
`R(time)`	`0.912317231017262`
`dL(time)`	`0.0`
`Cai(time)`	`1.0e-5`
`fL(time)`	`0.497133507285601`

shannon_wang_puglisi_weber_bers_2004 — v0.0.1

Shannon, Wang, Puglisi, Weber, Bers, 2004

Details

Parameters:

Name	Description
`Clo`	`150.0`
`G_tof`	`0.06`
`koff_Fluo3`	`0.11`
`stim_start`	`100.0`
`Km`	`0.0005`
`koff_SRB`	`0.06`
`Q10_CaL`	`1.8`
`kon_Myosin_Mg`	`0.0157`
`Bmax_Calsequestrin`	`0.14`
`D_Na_SL_cytosol`	`1.79e-5`
`G_CaBk`	`0.0002513`
`Cli`	`15.0`
`Bmax_SLB_jct`	`0.0046`
`EC50_SR`	`0.45`
`Indo1`	`0.0`
`Ko`	`5.4`
`PNa`	`1.5e-8`
`Fx_ICaL_SL`	`0.1`
`gamma_Nao`	`0.75`
`koff_TroponinC`	`0.0196`
`G_tos`	`0.02`
`Bmax_Indo1_Cytosol`	`0.025`
`kon_Myosin_Ca`	`13.8`
`Fx_NaBk_SL`	`0.89`
`Fx_ICaL_jct`	`0.9`
`Bmax_SL`	`1.65`
`Bmax_Calmodulin`	`0.024`
`Q10_SLCaP`	`2.35`
`kon_Indo1`	`100.0`
`koff_SLHigh`	`0.03`
`eta`	`0.35`
`Bmax_SLB_SL`	`0.0374`
`kon_TroponinC_Ca_Mg_Mg`	`0.003`
`Fx_SLCaP_jct`	`0.11`
`kim`	`0.005`
`kon_Calsequestrin`	`100.0`
`Q10_NaK`	`1.63`
`PK`	`2.7e-7`
`kon`	`0.0001`
`ksat`	`0.27`
`koff_Calmodulin`	`0.238`
`PCa`	`0.00054`
`Fx_CaBk_jct`	`0.11`
`jct_depth`	`0.015`
`Cao`	`1.8`
`SL_depth`	`0.045`
`Mgi`	`1.0`
`gamma_Nai`	`0.75`
`Mgo`	`1.0`
`I_NaK_max`	`1.91`
`Ki`	`135.0`
`Max_SR`	`15.0`
`Bmax_Myosin_Ca`	`0.14`
`Bmax_SRB`	`0.019`
`koCa`	`10.0`
`Q10_Km_Nai`	`1.49`
`koff_TroponinC_Ca_Mg_Ca`	`3.2e-5`
`H`	`1.787`
`Bmax_TroponinC`	`0.07`
`Bmax_TroponinC_Ca_Mg_Mg`	`0.14`
`ks`	`25.0`
`Nao`	`140.0`
`Kd_act`	`0.000256`
`K_mNai`	`12.29`
`HSR`	`2.5`
`Kmr`	`1.7`
`G_INa`	`16.0`
`Fx_NCX_jct`	`0.11`
`kon_Fluo3`	`100.0`
`g_Kp`	`0.001`
`stim_amplitude`	`9.5`
`Q10_NCX`	`1.57`
`jct_radius`	`0.16`
`Fx_NCX_SL`	`0.89`
`K_mCai`	`0.00359`
`F`	`96486.7`
`koff_Calsequestrin`	`65.0`
`gamma_Cai`	`0.341`
`gamma_Cao`	`0.341`
`K_mCao`	`1.3`
`K_mNao`	`87.5`
`T`	`310.0`
`pKNa`	`0.01833`
`kon_Calmodulin`	`34.0`
`koff`	`0.001`
`Bmax_SLHigh_jct`	`0.00165`
`Fluo3`	`0.0`
`Fx_NaBk_jct`	`0.11`
`Km_Nai`	`11.0`
`V_maxAF`	`0.0673`
`Q10_SRCaP`	`2.6`
`Fx_SLCaP_SL`	`0.89`
`koff_TroponinC_Ca_Mg_Mg`	`0.00333`
`Bmax_Indo1_jct`	`2.0e-5`
`Min_SR`	`1.0`
`Bmax_Myosin_Mg`	`0.14`
`Cm`	`1.381e-10`
`D_Ca_SL_cytosol`	`1.22e-6`
`Fx_Na_SL`	`0.89`
`koff_Indo1`	`0.06`
`Fx_Na_jct`	`0.11`
`koff_Myosin_Ca`	`0.00046`
`G_NaBk`	`0.000297`
`Bmax_TroponinC_Ca_Mg_Ca`	`0.14`
`Fx_Ks_SL`	`0.89`
`kon_SL`	`100.0`
`Fx_CaBk_SL`	`0.89`
`kon_TroponinC_Ca_Mg_Ca`	`2.37`
`V_max`	`9.0`
`Bmax_Fluo3_jct`	`2.0e-5`
`G_ClBk`	`0.009`
`Fx_Cl_jct`	`0.11`
`stim_duration`	`5.0`
`KSRleak`	`5.348e-6`
`Fx_NaK_jct`	`0.11`
`koff_Myosin_Mg`	`5.7e-5`
`Bmax_jct`	`3.7`
`Bmax_Fluo3_SL`	`0.00077`
`koff_SLB`	`1.3`
`Fx_Ks_jct`	`0.11`
`G_Cl`	`0.109625`
`Km_Ko`	`1.5`
`stim_period`	`1000.0`
`kon_TroponinC`	`32.7`
`kon_SRB`	`100.0`
`Cm_per_area`	`2.0e-6`
`gamma_Ki`	`0.75`
`kom`	`0.06`
`Fx_NaK_SL`	`0.89`
`x_SL_cytosol`	`0.45`
`Kd_ClCa`	`0.1`
`x_jct_SL`	`0.5`
`kiCa`	`0.5`
`Bmax_Fluo3_Cytosol`	`0.025`
`cell_length`	`100.0`
`A_jct_SL`	`3.01e-6`
`cell_radius`	`10.25`
`Kmf`	`0.000246`
`Bmax_SLHigh_SL`	`0.0134`
`gamma_Ko`	`0.75`
`Fx_Cl_SL`	`0.89`
`HNa`	`3.0`
`D_Ca_jct_SL`	`1.64e-6`
`Bmax_Indo1_SL`	`0.00077`
`A_SL_cytosol`	`0.00013`
`R`	`8314.3`
`H_NaK`	`4.0`
`D_Na_jct_SL`	`1.09e-5`

States:

Name	Description
`Y_tos(time)`	`0.293519921626`
`Ca_SLB_jct(time)`	`0.007780801995`
`Ca_SLB_SL(time)`	`0.009868629147`
`fCaB_SL(time)`	`0.015352888928`
`O(time)`	`7.11264e-7`
`Ca_jct(time)`	`0.000174843061`
`Nai(time)`	`8.874461106492`
`Na_SL(time)`	`8.874077316753`
`Ca_SLHigh_SL(time)`	`0.114438990328`
`V(time)`	`-85.719687955637`
`X_tos(time)`	`0.004011272375`
`Ca_SRB(time)`	`0.002177112381`
`Xs(time)`	`0.00687399199`
`fCaB_jct(time)`	`0.024609183734`
`R(time)`	`0.884673513138`
`Cai(time)`	`8.7350002e-5`
`Xr(time)`	`0.008471550841`
`Y_tof(time)`	`0.9946314893`
`Ca_TroponinC_Ca_Mg(time)`	`0.117995194438`
`Ca_Indo1_Cytosol(time)`	`0.0`
`Ca_Fluo3_Cytosol(time)`	`0.0`
`I(time)`	`9.272e-8`
`Na_jct_buf(time)`	`3.557055389701`
`R_tos_other(time)`	`0.383430556383`
`Ca_SLHigh_jct(time)`	`0.077503874257`
`Ca_Fluo3_jct(time)`	`0.0`
`f(time)`	`1.000675515962`
`Ca_Myosin(time)`	`0.001984672275`
`X_tof(time)`	`0.00401120993`
`Ca_Indo1_jct(time)`	`0.0`
`Na_SL_buf(time)`	`0.776121392467`
`j(time)`	`0.991822731369`
`Ca_Indo1_SL(time)`	`0.0`
`m(time)`	`0.001370685156`
`R_tos(time)`	`0.9946`
`Na_jct(time)`	`8.872823559072`
`d(time)`	`6.997531e-6`
`Ca_Fluo3_SL(time)`	`0.0`
`Mg_Myosin(time)`	`0.137497736234`
`h(time)`	`0.987140350343`
`Ca_Calsequestrin(time)`	`1.186496899338`
`Ca_SL(time)`	`0.000106395937`
`Mg_TroponinC_Ca_Mg(time)`	`0.010337654274`
`Ca_TroponinC(time)`	`0.008963736337`
`Ca_Calmodulin(time)`	`0.000295961245`
`Ca_SR(time)`	`0.545611267699`

shaw_chase_starfinger_smith_hann_desaive_ghuysen_2007 — v0.0.1

Shaw, Chase, Starfinger, Smith, Hann, Desaive, Ghuysen, 2007

Details

shaw_rudy_1997 — v0.0.1

Shaw, Rudy, 1997

Details

Parameters:

Name	Description
`gamma_Cai`	`nothing`
`gamma_Cao`	`nothing`
`T`	`nothing`
`TRPN_max`	`nothing`
`calcium_overload`	`nothing`
`P_Na`	`nothing`
`Km_Ca`	`nothing`
`delta_Ca_i2`	`nothing`
`K_mup`	`nothing`
`Ca_JSR_old`	`nothing`
`delta_Ca_ith`	`nothing`
`K_sat`	`nothing`
`K_05`	`nothing`
`gamma_Nao`	`nothing`
`tau_on`	`nothing`
`CMDN_max`	`nothing`
`Cm`	`nothing`
`P_ns_Ca`	`nothing`
`R_A_V`	`nothing`
`P_NaK`	`nothing`
`ATP_i`	`nothing`
`K_mNa`	`nothing`
`eta`	`nothing`
`V_myo`	`nothing`
`tau_tr`	`nothing`
`Ca_NSR_max`	`nothing`
`K_mCa`	`nothing`
`Cao`	`nothing`
`g_Nab`	`nothing`
`K_mpCa`	`nothing`
`gamma_Nai`	`nothing`
`Cai_old`	`nothing`
`K_mCSQN`	`nothing`
`t`	`nothing`
`gamma_Ki`	`nothing`
`I_st`	`nothing`
`K_m_ns_Ca`	`nothing`
`K_mCMDN`	`nothing`
`tau_off`	`nothing`
`A_cap`	`nothing`
`H`	`nothing`
`I_pCa`	`nothing`
`I_NaK`	`nothing`
`Nao`	`nothing`
`K_mTRPN`	`nothing`
`K_mNai`	`nothing`
`P_Ca`	`nothing`
`g_Na`	`nothing`
`I_up`	`nothing`
`V_cleft`	`nothing`
`g_Cab`	`nothing`
`CSQN_th`	`nothing`
`g_Kp`	`nothing`
`K_mrel`	`nothing`
`CSQN_max`	`nothing`
`g_Ca_T`	`nothing`
`gamma_Ko`	`nothing`
`Ko_normal`	`nothing`
`Nichols_area`	`nothing`
`K_NaCa`	`nothing`
`K_mKo`	`nothing`
`R`	`nothing`
`P_K`	`nothing`
`F`	`nothing`
`n`	`nothing`

States:

Name	Description
`d(time)`	`nothing`
`g(time)`	`nothing`
`delta_Cai(time)`	`nothing`
`V(time)`	`nothing`
`h(time)`	`nothing`
`Ca_NSR(time)`	`nothing`
`c1(time)`	`nothing`
`f(time)`	`nothing`
`b1(time)`	`nothing`
`Xs(time)`	`nothing`
`Ko(time)`	`nothing`
`Ki(time)`	`nothing`
`b(time)`	`nothing`
`j(time)`	`nothing`
`Ca_total(time)`	`nothing`
`m(time)`	`nothing`
`Xr(time)`	`nothing`
`Nai(time)`	`nothing`
`Ca_foot(time)`	`nothing`

shi_hose_2009 — v0.0.1

Shi, Hose, 2009

Details

Zero dimensional (lumped parameter) modelling of native human cardiovascular dynamics

shiferaw_watanabe_garfinkel_weiss_karma_2003 — v0.0.1

Shiferaw, Watanabe, Garfinkel, Weiss, Karma, 2003

Details

Parameters:

Name	Description
`BT`	`nothing`
`T`	`nothing`
`cup`	`nothing`
`K_sat`	`nothing`
`M`	`nothing`
`i_Ca_`	`nothing`
`cf_nsr`	`nothing`
`Vmax`	`nothing`
`gs`	`nothing`
`taur`	`nothing`
`tau_p`	`nothing`
`g`	`nothing`
`taus`	`nothing`
`K_mNa`	`nothing`
`eta`	`nothing`
`kd`	`nothing`
`vi`	`nothing`
`tau_tr`	`nothing`
`K_mCa`	`nothing`
`u`	`nothing`
`ko`	`nothing`
`tau_d`	`nothing`
`b`	`nothing`
`Cao`	`nothing`
`KCd`	`nothing`
`Vmin`	`nothing`
`a`	`nothing`
`kT_off`	`nothing`
`BSR`	`nothing`
`BCd`	`nothing`
`s`	`nothing`
`vs`	`nothing`
`A`	`nothing`
`Nao`	`nothing`
`alpha`	`nothing`
`P_Ca`	`nothing`
`taua`	`nothing`
`cp_`	`nothing`
`tau_f`	`nothing`
`kT_on`	`nothing`
`KSR`	`nothing`
`m`	`nothing`
`vup`	`nothing`
`gamma`	`nothing`
`K_NaCa`	`nothing`
`R`	`nothing`
`F`	`nothing`
`cs_`	`nothing`

States:

Name	Description
`d(time)`	`nothing`
`CaTi(time)`	`nothing`
`I_r(time)`	`nothing`
`CaTs(time)`	`nothing`
`cp(time)`	`nothing`
`cj(time)`	`nothing`
`a(time)`	`nothing`
`cj_(time)`	`nothing`
`f(time)`	`nothing`
`ci(time)`	`nothing`
`cf_jsr(time)`	`nothing`
`cs(time)`	`nothing`
`q(time)`	`nothing`

shorten_robson_mckinnon_wall_2000 — v0.0.1

Shorten, Robson, Mckinnon, Wall, 2000

Details

Parameters:

Name	Description
`k_n`	`4.5`
`V_h_T`	`-57.0`
`K_i`	`140.0`
`T`	`310.0`
`I_max`	`2.7`
`v_p`	`0.025`
`k_tau`	`22.0`
`K_p`	`0.08`
`Ca_e`	`20.0`
`f_cyt`	`0.005`
`g_K_Ca`	`0.09`
`K_e`	`5.6`
`k_m_L`	`12.0`
`V_tau`	`-60.0`
`Cm`	`7.0`
`ks`	`6.5`
`V_m_L`	`-12.0`
`tau_n`	`20.0`
`tau_h_T`	`15.0`
`tau_m_T_max`	`10.0`
`k_h_T`	`5.0`
`V_m_T`	`-30.0`
`g_K_IR`	`0.3`
`alpha`	`0.0074`
`beta`	`0.4`
`tau_m_L_max`	`27.0`
`k_m_T`	`10.5`
`g_Ca_L`	`9.0`
`g_K_DR`	`0.1`
`g_Ca_T`	`10.0`
`V_n`	`-20.0`
`V_K_IR`	`-71.5`
`R`	`8.314`
`F`	`96845.0`
`Kc`	`0.5`

States:

Name	Description
`h_T(time)`	`nothing`
`V(time)`	`nothing`
`n(time)`	`nothing`
`Ca_i(time)`	`nothing`
`m_T(time)`	`nothing`
`m_L(time)`	`nothing`

shorten_wall_2000 — v0.0.1

Shorten, Wall, 2000

Details

Parameters:

Name	Description
`k_n`	`4.5`
`V_h_T`	`-57.0`
`K_i`	`140.0`
`T`	`310.0`
`P`	`0.0012`
`v_p`	`4.5e-5`
`k_tau`	`22.0`
`K_p`	`8.0e-5`
`Ca_e`	`20.0`
`V_cell`	`1.77`
`f_cyt`	`0.01`
`f_er`	`0.0025`
`K_e`	`5.6`
`g_K_Ca`	`0.09`
`K_er`	`0.0002`
`k_m_L`	`12.0`
`V_tau`	`-60.0`
`Cm`	`7.0`
`V_m_L`	`-18.0`
`tau_n`	`20.0`
`tau_h_T`	`15.0`
`tau_m_T_max`	`10.0`
`k_h_T`	`5.0`
`V_m_T`	`-30.0`
`alpha`	`7.4e-6`
`g_L`	`0.3`
`V_L`	`-67.0`
`beta`	`0.47`
`tau_m_L_max`	`27.0`
`k_m_T`	`10.5`
`v_er`	`5.0e-5`
`g_Ca_L`	`9.0`
`g_K_DR`	`0.1`
`g_Ca_T`	`10.0`
`V_n`	`-20.0`
`R`	`8314.0`
`F`	`96845.0`
`Kc`	`0.0004`

States:

Name	Description
`h_T(time)`	`0.0`
`V(time)`	`-70.0`
`n(time)`	`0.0`
`Ca_i(time)`	`0.00026`
`Ca_er(time)`	`0.0172`
`m_T(time)`	`0.0`
`m_L(time)`	`0.0`

shrestha_hollot_chipkin_schmitt_chait_2010 — v0.0.1

Shrestha, Hollot, Chipkin, Schmitt and Chait 2010

Details

Parameters:

Name	Description
`t0`	`575.0`
`m2`	`15.0`
`alpha`	`0.0442`
`x2_max`	`14.043`
`m1`	`112.52`
`Ca_1`	`0.1817`
`x2_n`	`6.629`
`beta`	`1.0e6`
`lambda1`	`0.0125`
`x1_n`	`490.78`
`Ca_0`	`1.255`
`R`	`1.2162`
`x2_min`	`0.6697`
`lambda2`	`0.5595`

States:

Name	Description
`x2(time)`	`0.0`
`x1(time)`	`0.0`

siebert_rode_herzog_till_blickhan_2008 — v0.0.1

Siebert, Rode, Herzog, Till and Blickhan, 2008

Details

Parameters:

Name	Description
`k_1`	`0.012`
`curv`	`5.8`
`A`	`1.0`
`k`	`3.5`
`L_1`	`-23.0`
`tau`	`0.006`
`delta_L_sec1`	`4.1`
`L_4`	`19.0`
`f_c`	`0.49`
`L_mslack`	`0.3`
`k_sh`	`3.3`
`v_max`	`-141.0`
`F_im`	`18.1`
`k_2`	`0.317`
`L_m`	`0.3`
`L_2`	`-14.0`
`d_LSEC1`	`4.1`
`L_3`	`2.0`
`F_1`	`4.1`

States:

Name	Description
`f_v(time)`	`nothing`
`L_cc(time)`	`nothing`
`delta_L_pec(time)`	`nothing`

sine — v0.0.1

Approximating Sine Waves

Details

A test CellML 1.1 model which has a couple of sine approximations. This workspace and the data in it is primarily used for testing various things out.

sine-approximations: sine_approximations — v0.0.1

Sine-Approximations

Details

skouibine_trayanova_moore_1999 — v0.0.1

Skouibine, Trayanova, Moore, 1999

Details

Parameters:

Name	Description
`I_stim`	`nothing`
`C`	`nothing`
`g_s`	`nothing`
`g_Na`	`nothing`
`E_Na`	`nothing`
`R_d`	`nothing`
`R_f`	`nothing`

States:

Name	Description
`d(time)`	`0.0`
`V(time)`	`-86.9`
`h(time)`	`0.99`
`m(time)`	`0.0`
`Cai(time)`	`0.0001`
`f(time)`	`1.0`
`x1(time)`	`0.0`