CellMLPhysiome: J - N
J
joseph_zavros_merchant_kirschner_2003 — v0.0.1Joseph, Zavros, Merchant, Kirschner, 2003
Details
Parameters:
| Name | Description |
|---|---|
gamma_DC | nothing |
f | nothing |
KNS | nothing |
N_ | nothing |
alpha_AS | nothing |
alpha_Csc | nothing |
Nmax1 | nothing |
alpha_Fd | nothing |
gamma_P | nothing |
alpha_NH | nothing |
alpha_GS | nothing |
hb | nothing |
beta_A | nothing |
kFd | nothing |
gamma_DA | nothing |
gamma_Fdmax | nothing |
Bas1 | nothing |
alpha_HA | nothing |
kSA | nothing |
KAS | nothing |
kappa_NC | nothing |
k_BCmax | nothing |
Bas2 | nothing |
Nmax2 | nothing |
C_Csc | nothing |
KNG1 | nothing |
gamma_E | nothing |
kNS | nothing |
alpha_NG2 | nothing |
gamma_Asc | nothing |
KGA | nothing |
k_gmax | nothing |
kG | nothing |
KHA | nothing |
alpha_GA | nothing |
alpha_NG1 | nothing |
KNG2 | nothing |
kappa_H | nothing |
beta_G | nothing |
k_dmax | nothing |
alpha_GH | nothing |
kSG | nothing |
KNH | nothing |
KNA | nothing |
kappa_NE | nothing |
kSS | nothing |
gamma_Csc | nothing |
KFG | nothing |
kappa_A | nothing |
kappa_G | nothing |
C_Asc | nothing |
kappa_S | nothing |
kAN2 | nothing |
KGH | nothing |
T_Asc | nothing |
kAN1 | nothing |
alpha_NS | nothing |
Fd | nothing |
gmax | nothing |
alpha_NA | nothing |
gamma_Gc | nothing |
T_Csc | nothing |
k_Emax | nothing |
KGS | nothing |
k_Fdmax | nothing |
alpha_NB | nothing |
beta_B | nothing |
kSH | nothing |
alpha_E | nothing |
kappa_B | nothing |
kAG | nothing |
k_BAmax | nothing |
States:
| Name | Description |
|---|---|
P(time) | nothing |
DC(time) | nothing |
GtnA(time) | nothing |
BC(time) | nothing |
GtnC(time) | nothing |
Asc(time) | nothing |
NE(time) | nothing |
HC(time) | nothing |
AA(time) | nothing |
SA(time) | nothing |
SC(time) | nothing |
DA(time) | nothing |
E(time) | nothing |
BA(time) | nothing |
NC(time) | nothing |
Csc(time) | nothing |
G(time) | nothing |
AC(time) | nothing |
K
karagiannis_popel_2004 — v0.0.1Karagiannis, Popel, 2004
Details
Parameters:
| Name | Description |
|---|---|
kcat_M2C1 | 0.0045 |
kiso_M2T2 | 33.0 |
kon_MT1T2M2P | 140000.0 |
kon_MT1T2 | 3.54e6 |
kshed_eff | 2800.0 |
ki_M2T2 | 1.07e-6 |
kon_M2T2 | 5.9e6 |
kon_M2C1 | 2600.0 |
kcat_MT1C1 | 0.00197 |
km_MT1C1 | 2.9e-6 |
koff_M2C1 | 0.0021 |
kact_eff_m2 | 2800.0 |
k_iso_M2T2 | 2.0e-8 |
ki_MT1T2 | 4.9e-9 |
koff_MT1T2M2P | 0.0047 |
States:
| Name | Description |
|---|---|
M2T2star(time) | 0.0 |
MT1cat(time) | 0.0 |
M2T2(time) | 0.0 |
M2(time) | 0.0 |
M2P(time) | 5.0e-8 |
C1(time) | 1.0e-6 |
T2(time) | 5.0e-8 |
MT1(time) | 1.0e-7 |
C1dm2(time) | 0.0 |
C1dmt1(time) | 0.0 |
M2C1(time) | 0.0 |
MT1T2M2P(time) | 0.0 |
MT1T2(time) | 0.0 |
karagiannis_popel_2006 — v0.0.1Karagiannis, Popel, 2006
Details
Parameters:
| Name | Description |
|---|---|
kM2T2_on | 5.9e6 |
kMT1T2_on | 2.98e6 |
kMT1C1_on | 1000.0 |
kM2T2_negativeiso | 2.0e-8 |
qMT1 | 0.0 |
kMT1T2M2proMT1_off | 0.0009 |
kM2C1_off | 0.0021 |
kM2C1_on | 2600.0 |
kM2T2_off | 6.3 |
kMT1_shedeff | 2800.0 |
kMT1T2_off | 0.202 |
kMT1C1_off | 1.0 |
kMT1C1_cat | 0.00197 |
kMT1T2M2pro_off | 0.0047 |
kM2T2_iso | 33.0 |
kMT1T2M2proMT1_on | 3000.0 |
kM2_act | 0.02 |
kM2C1_cat | 0.0045 |
qT2 | 0.0 |
qpro | 0.0 |
kMT1T2M2pro_on | 140000.0 |
States:
| Name | Description |
|---|---|
M2C1(t) | 8.5e-6 |
MT1T2M2pro(t) | 0.0 |
C1_D(t) | 0.0 |
C1(t) | 0.0 |
MT1_cat(t) | 0.0 |
M2T2(t) | 7.2e-9 |
MT1T2M2proMT1(t) | 5.6e-10 |
M2_p(t) | 0.0 |
M2T2_star(t) | 0.0 |
MT1C1(t) | 2.9e-6 |
MT1T2(t) | 1.39e-9 |
MT1(t) | 0.0 |
T2(t) | 0.0 |
MT1_t(t) | 0.0 |
MT1T2_star(t) | 0.0 |
M2(t) | 0.0 |
katsnelson_nikitina_chemla_solovyova_coirault_lecarpentier_markhasin_2004 — v0.0.1Katsnelson, Nikitina, Chemla, Solovyova, Coirault, Lecarpentier, Markhasin, 2004
Details
Parameters:
| Name | Description |
|---|---|
a_c | 5200.0 |
alpha_P_lengthening | 16.0 |
t_d | 0.033 |
k_A | 2.8 |
q_Ca | 50.0 |
alpha_2 | 14.6 |
S_0 | 1.14 |
beta_P_lengthening | 0.0015 |
a_on | 2300.0 |
Ca_m | 0.03 |
B_tot | 0.4 |
m_0 | 0.9 |
r_Ca | 650.0 |
beta_S_shortening | 0.006 |
beta_2 | 0.000924 |
beta_Q | 5000.0 |
beta_3 | 0.01 |
F_afterload | 2.0 |
alpha_G | 1.0 |
b_on | 2600.0 |
alpha_S_shortening | 46.0 |
A_tot | 1.0 |
q_3 | 17.3 |
chi_0 | 3.0 |
a_off | 290.0 |
a | 0.25 |
mu | 3.0 |
alpha_Q | 10.0 |
l_0 | 0.527 |
v_star | 5.3035675 |
chi | 0.705 |
A_half | 0.6 |
v_max | 5.6 |
q_1 | 17.3 |
lambda | 96.0 |
q_star | 1000.0 |
alpha_3 | 48.0 |
isotonic | 0.0 |
q_4 | 15.0 |
alpha_1 | 19.0 |
q_2 | 259.0 |
v_0 | 560.0 |
beta_P_shortening | 0.0015 |
alpha_S_lengthening | 39.0 |
alpha_P_shortening | 16.0 |
b_off | 182.0 |
beta_S_lengthening | 0.008 |
beta_1 | 0.29 |
d_h | 0.5 |
alpha_P | 4.0 |
States:
| Name | Description |
|---|---|
N(time) | 0.0001 |
l_3(time) | 0.089 |
A(time) | 0.01 |
l_2(time) | 0.439 |
v(time) | 0.0 |
l_1(time) | 0.437 |
w(time) | 0.0 |
B(time) | 0.0 |
Ca_C(time) | 0.0 |
keener_2001 — v0.0.1Keener, 2001
Details
keizer_levine_1996 — v0.0.1Keizer, Levine, 1996
Details
Parameters:
| Name | Description |
|---|---|
kb_ | 385.9 |
ka | 1500.0 |
kc_ | 0.1 |
c1 | 0.15 |
kc | 1.75 |
fi | 0.01 |
n | 4.0 |
v1 | 40.0 |
Co | 10.0 |
ka_ | 28.8 |
m | 3.0 |
v2 | 0.5 |
kb | 1500.0 |
v3 | 1000.0 |
K3 | 0.3 |
States:
| Name | Description |
|---|---|
P_O1(time) | nothing |
P_C1(time) | nothing |
P_C2(time) | nothing |
P_O2(time) | nothing |
Cai(time) | nothing |
w(time) | nothing |
kesmir_deboer_1999 — v0.0.1Kesmir, Deboer, 1999
Details
Parameters:
| Name | Description |
|---|---|
pr | 0.15 |
SA | 500.0 |
mu | 3.0 |
rho | 4.0 |
sigma | 5.0 |
ST | 50.0 |
delta_T | 0.8 |
KB | 10000.0 |
KT | 100.0 |
u | 0.15 |
z | 0.02 |
delta_B | 0.8 |
p | 2.0 |
d | 2.0 |
States:
| Name | Description |
|---|---|
B10(time) | 0.0 |
B9(time) | 0.0 |
B1(time) | 0.0 |
B5(time) | 0.0 |
C_star(time) | 0.0 |
B8(time) | 0.0 |
M(time) | 0.0 |
T(time) | 0.0 |
B0(time) | 3.0 |
C(time) | 0.0 |
B3(time) | 0.0 |
B7(time) | 0.0 |
A(time) | 500.0 |
B2(time) | 0.0 |
B4(time) | 0.0 |
B6(time) | 0.0 |
kholodenko_demin_moehren_hoek_1999 — v0.0.1Kholodenko, Demin, Moehren, Hoek, 1999
Details
Parameters:
| Name | Description |
|---|---|
k14 | 6.0 |
k18 | 0.3 |
k25 | 1.0 |
k9 | 0.003 |
k15_ | 0.0009 |
k6_ | 0.05 |
k12_ | 0.0001 |
k21_ | 0.1 |
k10_ | 0.06 |
K16 | 340.0 |
k1_ | 0.06 |
k5_ | 0.2 |
V8 | 1.0 |
k12 | 0.0015 |
K4 | 50.0 |
K8 | 100.0 |
k3 | 1.0 |
k17 | 0.003 |
k22_ | 0.064 |
k20 | 0.12 |
k21 | 0.003 |
k10 | 0.01 |
k13 | 0.09 |
k18_ | 0.0009 |
k7_ | 0.006 |
k15 | 0.3 |
V16 | 1.7 |
k23_ | 0.021 |
k20_ | 0.00024 |
k19 | 0.01 |
k9_ | 0.05 |
k14_ | 0.06 |
k22 | 0.03 |
k13_ | 0.6 |
k6 | 1.0 |
k11 | 0.03 |
k23 | 0.1 |
V4 | 450.0 |
k11_ | 0.0045 |
k17_ | 0.1 |
k3_ | 0.01 |
k1 | 0.003 |
k2_ | 0.1 |
k7 | 0.3 |
k24_ | 0.0429 |
k25_ | 0.03 |
k19_ | 0.0214 |
k5 | 0.06 |
k24 | 0.009 |
k2 | 0.01 |
States:
| Name | Description |
|---|---|
R_Sh_G(time) | 0.0 |
EGF(time) | 680.0 |
R_PL(time) | 0.0 |
R2(time) | 0.0 |
R_ShP(time) | 0.0 |
Ra(time) | 0.0 |
R_Sh_G_S(time) | 0.0 |
Sh_G(time) | 0.0 |
G_S(time) | 0.0 |
R_G_S(time) | 0.0 |
ShP(time) | 0.0 |
Sh_G_S(time) | 0.0 |
R_PLP(time) | 0.0 |
RP(time) | 0.0 |
PLC_gamma(time) | 105.0 |
PLC_gamma_P_I(time) | 0.0 |
SOS(time) | 34.0 |
Grb(time) | 85.0 |
PLC_gamma_P(time) | 0.0 |
R_Sh(time) | 0.0 |
R(time) | 100.0 |
R_G(time) | 0.0 |
Shc(time) | 150.0 |
kirschner_panetta_1998 — v0.0.1Kirschner, Panetta, 1998
Details
Parameters:
| Name | Description |
|---|---|
mu3 | 10.0 |
s1 | 0.0 |
c | 0.02 |
b | 1.0e-9 |
mu2 | 0.03 |
s2 | 0.0 |
a | 1.0 |
r2 | 0.18 |
p2 | 5.0 |
g2 | 100000.0 |
p1 | 0.1245 |
g1 | 2.0e-7 |
g3 | 1000.0 |
States:
| Name | Description |
|---|---|
x(tau) | 1.0 |
z(tau) | 1.0 |
y(tau) | 1.0 |
kirschner_webb_1996 — v0.0.1Kirschner, Webb, 1996
Details
kneller_ramirez_chartier_courtemanche_nattel_2002 — v0.0.1Kneller, Ramirez, Chartier, Courtemanche, Nattel, 2002
Details
Parameters:
| Name | Description |
|---|---|
T | 310.0 |
TRPN_max | 0.35 |
K_rel | 30.0 |
Ca_up_max | 15.0 |
g_Cl_Ca | 0.3 |
V_rel | 96.48 |
q_Ca | 0.0 |
K_sat | 0.1 |
delta_CT_n | 87.8251 |
i_NaK_max | 0.6 |
I_up_max | 0.005 |
g_Ca | 0.24 |
CMDN_max | 0.045 |
g_B_Cl | 0.0018 |
g_to | 0.19824 |
Cm | 100.0 |
g_B_K | 0.0 |
Km_K_o | 1.5 |
K_mNa | 87.5 |
g_Ks | 0.0561 |
g_K1 | 0.15 |
tau_tr | 180.0 |
g_Kr | 0.06984 |
I_NaCa_max | 1600.0 |
K_mCa | 1.38 |
Na_o | 140.0 |
tau_q_Ca | 2.0 |
K_up | 0.00092 |
g_B_Na | 0.000674 |
Ca_o | 1.8 |
K_o | 5.4 |
V_i | 13668.0 |
i_stim | -2900.0 |
g_Na | 7.8 |
g_B_Ca | 0.00113 |
g_CT | 0.115 |
V_up | 1109.52 |
i_p_Ca_max | 0.275 |
CSQN_max | 10.0 |
Cl_o | 132.0 |
Km_Na_i | 10.0 |
tau_f_Ca | 2.0 |
R | 8.3143 |
F | 96.4867 |
n | 4.0 |
States:
| Name | Description |
|---|---|
Ca_CMDN(time) | nothing |
oa(time) | nothing |
oi(time) | nothing |
Cl_i(time) | nothing |
xr(time) | nothing |
v(time) | nothing |
xs(time) | nothing |
f(time) | nothing |
ui(time) | nothing |
u(time) | nothing |
j(time) | nothing |
m(time) | nothing |
Na_i(time) | nothing |
w(time) | nothing |
d(time) | nothing |
Ca_rel(time) | nothing |
V(time) | nothing |
h(time) | nothing |
ua(time) | nothing |
Ca_TRPN(time) | nothing |
K_i(time) | nothing |
Ca_CSQN(time) | nothing |
f_Ca(time) | nothing |
J_Ca_CSQN(time) | nothing |
Ca_up(time) | nothing |
Ca_i(time) | nothing |
J_Ca_TRPN(time) | nothing |
J_Ca_CMDN(time) | nothing |
koivumaki_2009 — v0.0.1Koivumaki,2009
Details
Parameters:
| Name | Description |
|---|---|
Kmf_PLB | 0.15 |
Na_i | 14000.0 |
C_m | 1.0 |
T | 298.0 |
PKA_reg | 0.1 |
kltrpn_pos | 0.1 |
SERCA_TOT | 47.0 |
kplb_neg | 6.8 |
Kmr_PLBKO | 2500.0 |
Ca_cyt | 0.25 |
Ca_NSR | 760.0 |
eta | 0.35 |
LTRPN_tot | 70.0 |
V_myo | 2.584e-5 |
Acap | 0.0001534 |
Km_CaM | 2.38 |
PLB_tot | 1.0 |
A1 | 110.0 |
PSR | 1.0 |
ksat | 0.1 |
br_serca_sr | 0.00625 |
Ca_pow | 2.0 |
kplb_pos | 1.0 |
Na_o | 140000.0 |
Ca_tau1 | 1.5 |
Ca_tau2 | 14.0 |
CaM_tot | 24.0 |
Ca_o | 1000.0 |
rest | -80.0 |
KmCa | 1380.0 |
J_leak | 0.0003 |
KmNa | 87500.0 |
CaMKII_reg | 0.0 |
A | 150.0 |
Kmf_PLBKO | 0.15 |
t2 | 8.0 |
kltrpn_neg | 0.06 |
t1 | 0.5 |
Kmr_PLB | 1110.0 |
kNaCa | 950.0 |
Ca_amp | 2.9 |
R | 8.314 |
F | 96.5 |
p | 2.0 |
States:
| Name | Description |
|---|---|
Ca_serca(time) | 12.0 |
LTRPN(time) | 11.0 |
Ca_cyt(time) | 0.1 |
PLB_dephosph(time) | 0.1 |
komarova_2005 — v0.0.1Komarova 2005
Details
Parameters:
| Name | Description |
|---|---|
g22 | 0.0 |
beta2 | 0.02 |
g12 | 1.0 |
alpha2 | 4.0 |
alpha1 | 3.0 |
g11 | 0.5 |
k1 | 0.24 |
beta1 | 0.2 |
k2 | 0.0017 |
States:
| Name | Description |
|---|---|
x2(time) | 212.132 |
z(time) | 100.0 |
x1(time) | 10.06066 |
komarova_smith_dixon_sims_wahl_2003 — v0.0.1Komarova, Smith, Dixon, Sims and Wahl, 2003
Details
Parameters:
| Name | Description |
|---|---|
g22 | 0.0 |
g21 | -0.5 |
beta2 | 0.02 |
g12 | 1.0 |
alpha2 | 4.0 |
alpha1 | 3.0 |
g11 | 1.1 |
k1 | 0.093 |
beta1 | 0.2 |
k2 | 0.0008 |
States:
| Name | Description |
|---|---|
x2(time) | 212.132 |
z(time) | 100.0 |
x1(time) | 10.06066 |
komarova_wodarz_2003 — v0.0.1Komarova, Wodarz, 2003
Details
Parameters:
| Name | Description |
|---|---|
r_5 | 1.0 |
r_1 | 0.6 |
r_3 | 0.8 |
alpha | 0.1 |
r_2 | 0.7 |
a | 0.5 |
r_4 | 0.9 |
r_8 | 1.3 |
r_6 | 1.1 |
beta | 0.2 |
rm | 1.3 |
rs | 1.0 |
epsilon_m | 0.1 |
r_0 | 0.5 |
r_7 | 1.2 |
u | 0.07 |
epsilon_s | 0.99 |
States:
| Name | Description |
|---|---|
S_6(time) | 0.0 |
M_2(time) | 0.0 |
M_0(time) | 0.5 |
S_7(time) | 0.0 |
M_4(time) | 0.0 |
S_3(time) | 0.0 |
S_1(time) | 0.0 |
S_5(time) | 0.0 |
w(time) | 0.0 |
M_1(time) | 0.0 |
S_4(time) | 0.0 |
M(time) | 0.5 |
M_7(time) | 0.0 |
S_2(time) | 0.0 |
M_3(time) | 0.0 |
S_0(time) | 0.5 |
M_1_2(time) | 0.0 |
M_6(time) | 0.0 |
M_8(time) | 0.0 |
S(time) | 0.5 |
M_5(time) | 0.0 |
S_8(time) | 0.0 |
kongas_vanbeek_2001 — v0.0.1Kongas, Vanbeek, 2001
Details
Parameters:
| Name | Description |
|---|---|
Vb | 29250.0 |
R_ADP | 8.16 |
Kia | 900.0 |
V_hyd | 4600.0 |
R_ATP | 8.16 |
R_Cr | 14.6 |
V_syn_max | 4600.0 |
Kid | 4730.0 |
Kic | 222.4 |
R_PCr | 14.6 |
V_cyt | 0.75 |
KPi | 20.0 |
Kib | 34900.0 |
KADP | 800.0 |
Kb | 15500.0 |
R_Pi | 18.4 |
Kd | 1670.0 |
V_ims | 0.0625 |
Vf | 6966.0 |
States:
| Name | Description |
|---|---|
PCr_i(time) | 12500.0 |
Pi(time) | 8000.0 |
PCr(time) | 12500.0 |
Cr(time) | 13500.0 |
ATP_i(time) | 9644.425 |
ADP_i(time) | 2.5 |
Cr_i(time) | 13500.0 |
ATP(time) | 9644.425 |
Pi_i(time) | 8000.0 |
ADP(time) | 60.0 |
korzeniewski_zoladz_2001 — v0.0.1Korzeniewski, Zoladz, 2001
Details
Parameters:
| Name | Description |
|---|---|
k_EFF | 1.9258 |
kSN | 34316.0 |
T | 289.0 |
Ae_SUM | 1600.2 |
nA | 2.5 |
protonmotive_force | 190.0 |
kC1 | 238.95 |
kPI | 69.421 |
kDH | 28074.0 |
Nt | 2970.0 |
c_buffi | 0.022 |
kL1 | 2.5 |
pKa | 6.8 |
c_buffe | 0.025 |
kL2 | 0.038 |
kUT | 686.5 |
pD | 0.8 |
KmO | 120.0 |
km_A | 150.0 |
Ai_SUM | 16260.0 |
kDDi | 282.0 |
pH_o | 7.0 |
dpH | 0.001 |
Mg_fi | 380.0 |
C_SUM | 35000.0 |
kDTi | 17.0 |
kEX | 54572.0 |
kDDe | 347.0 |
R_cm | 15.0 |
kC3 | 136.41 |
kf_CK | 1.9258 |
EmU0 | 85.0 |
at | 135.0 |
Ema0 | 540.0 |
BN | 5.0 |
km_ADP | 3.5 |
kf_AK | 862.1 |
Mg_fe | 4000.0 |
ct | 270.0 |
kb_CK | 0.00087538 |
KmN | 100.0 |
kDTe | 24.0 |
kC4 | 136.41 |
Emc0 | 250.0 |
kb_AK | 22.747 |
delta_Gp0 | 31.9 |
R | 0.0083 |
Ut | 1350.0 |
EmN0 | -320.0 |
F | 0.0965 |
States:
| Name | Description |
|---|---|
UQH2(time) | 1.0 |
ATP_ti(time) | 1.0 |
NADH(time) | 500.0 |
Hi(time) | 1.0 |
PCr(time) | 1.0 |
ADP_te(time) | 1.0 |
O2(time) | 1.0 |
He(time) | 1.0 |
Pi_te(time) | 1.0 |
Pi_ti(time) | 1.0 |
c_2(time) | 1.0 |
a_2(time) | 1.0 |
ATP_te(time) | 1.0 |
kroll_2000 — v0.0.1Kroll, 2000
Details
Parameters:
| Name | Description |
|---|---|
C3 | 1.0 |
K2 | 2.0 |
C | 50.0 |
k1 | 1.0 |
C1 | 1.0 |
C2 | 1.0 |
k4 | 0.9 |
k3 | 0.05 |
k6 | 0.02 |
K | 5.0 |
k5 | 5.0 |
k2 | 1.3 |
ky | 0.01 |
States:
| Name | Description |
|---|---|
P(time) | 10.0 |
Z(time) | 200.0 |
X(time) | 500.0 |
Y(time) | 10.0 |
IL6(time) | 1.9 |
kummer_2000 — v0.0.1Switching from Simple to Complex Oscillations in Calcium Signaling
Details
We present a new model for calcium oscillations based on experiments in hepatocytes. The model considers feedback inhibition on the initial agonist receptor complex by calcium and activated phospholipase C, as well as receptor type-dependent self-enhanced behavior of the activated G(alpha) subunit. It is able to show simple periodic oscillations and periodic bursting, and it is the first model to display chaotic bursting in response to agonist stimulations. Moreover, our model offers a possible explanation for the differences in dynamic behavior observed in response to different agonists in hepatocytes.
Parameters:
| Name | Description |
|---|---|
k14 | 153.0 |
k2 | 2.9259 |
k10 | 13.58 |
K11 | 2.67 |
k13 | 0.12 |
K15 | 0.16 |
k12 | 0.7 |
k16 | 4.85 |
k1 | 0.212 |
k8 | 32.24 |
K4 | 0.19 |
K17 | 0.05 |
k3 | 1.52 |
K9 | 29.09 |
k7 | 1.24 |
K12 | 0.16 |
k5 | 4.88 |
K6 | 1.18 |
k11 | 153.0 |
States:
| Name | Description |
|---|---|
d(time) | 20.0 |
b(time) | 0.01 |
c(time) | 0.01 |
a(time) | 0.01 |
kurata_hisatome_imanishi_shibamoto_2002 — v0.0.1Kurata, Hisatome, Imanishi, Shibamoto, 2002
Details
Parameters:
| Name | Description |
|---|---|
K3ni | 26.44 |
T | 310.15 |
Km_fCa | 0.00035 |
K_rel | 0.0012 |
TC_tot | 0.031 |
Km_Kp | 1.4 |
kf_TC | 88.8 |
g_h_Na | 0.1437375 |
Km_Nap | 14.0 |
V_rel | 4.2223e-15 |
K1ni | 395.3 |
i_NaK_max | 3.6 |
Ko | 5.4 |
g_to | 0.18 |
Kcni | 26.44 |
Cm | 32.0 |
kb_TC | 0.446 |
Qco | 0.0 |
g_h_K | 0.2312625 |
kf_TMM | 2.277 |
Kco | 3.663 |
g_Ks | 0.0259 |
kf_CM | 227.7 |
TMC_tot | 0.062 |
tau_tr | 60.0 |
g_sus | 0.02 |
kf_CQ | 0.534 |
P_rel | 0.5 |
beta_fCa | 60.0 |
CQ_tot | 10.0 |
K1no | 1628.0 |
K_up | 0.0006 |
kb_CM | 0.542 |
Cao | 2.0 |
Mgi | 2.5 |
K2no | 561.4 |
tau_dif_Ca | 0.04 |
Qn | 0.4315 |
g_st | 0.015 |
kb_TMM | 0.751 |
K3no | 4.663 |
g_b_Na | 0.0054 |
V_i | 1.5835e-12 |
K2ni | 2.289 |
kf_TMC | 227.7 |
E_CaL | 45.0 |
kb_CQ | 0.445 |
P_up | 0.005 |
Nao | 140.0 |
Qci | 0.1369 |
Kci | 0.0207 |
E_st | 37.4 |
V_sub | 3.5098e-14 |
kb_TMC | 0.00751 |
V_up | 4.0816e-14 |
kNaCa | 125.0 |
g_CaT | 0.458 |
CM_tot | 0.045 |
g_CaL | 0.58 |
R | 8.3144e15 |
F | 9.6485e16 |
E_CaT | 45.0 |
States:
| Name | Description |
|---|---|
qa(time) | 0.426018100136 |
paF(time) | 0.3493633709533 |
piy(time) | 0.852396631172 |
f(time) | 0.626999773853 |
y(time) | 0.067156687129 |
fCQ(time) | 0.260317260703 |
fTC(time) | 0.059206293446 |
n(time) | 0.054409723782 |
fCMs(time) | 0.074631965653 |
Ca_sub(time) | 0.00019074741 |
fTMC(time) | 0.602955114871 |
Nai(time) | 9.438646305915 |
q(time) | 0.531446952485 |
d(time) | 0.000602055134 |
Ca_rel(time) | 0.296742023718 |
fTMM(time) | 0.350600895635 |
V(time) | -58.600291137693 |
fCa(time) | 0.589580408056 |
Ki(time) | 139.984146485614 |
fCMi(time) | 0.116947220413 |
r(time) | 0.005550489445 |
qi(time) | 0.333330378068 |
Ca_up(time) | 1.462338380106 |
Cai(time) | 0.000312494921 |
paS(time) | 0.629323128348 |
kyrylov_severyanova_vieira_2005 — v0.0.1Kyrylov, Severyanova, Vieira, 2005
Details
Parameters:
| Name | Description |
|---|---|
a21 | 0.031 |
a22 | -0.0957 |
a42 | 0.000139 |
a12 | -0.0668 |
S4 | 0.01 |
a33 | -0.00857 |
a44 | -0.000143 |
a00 | -0.00843 |
S1 | 0.01 |
S3 | 0.01 |
S2 | 0.01 |
e2 | 0.0 |
a11 | -0.004 |
a10 | 0.082 |
e0 | 0.0 |
a23 | 0.0576 |
S0 | 0.01 |
epsilon | 0.5 |
a02 | -0.44 |
c0 | 0.443 |
a20 | 0.0 |
a24 | 0.000325 |
e1 | 0.0 |
a32 | 0.00869 |
States:
| Name | Description |
|---|---|
y2(time) | 1.17 |
y3(time) | 0.95 |
y1(time) | 1.4 |
y4(time) | 0.65 |
y0(time) | 0.4 |
L
lambeth_kushmerick_2002 — v0.0.1Lambeth, Kushmerick, 2002
Details
Parameters:
| Name | Description |
|---|---|
Keq_GAPDH | 0.089 |
K_F6P | 0.18 |
V_max_f | 12000.0 |
var_e | 0.01 |
Keq_PGK | 57109.0 |
Keq_CK | 233.0 |
K_G6P | 0.18 |
Keq_ALD | 9.5e-5 |
K_ATP_ | 0.25 |
Keq_ENOL | 0.49 |
K_G1P | 1.5 |
K_AMP | 1.9e-6 |
K_FBP | 4.02 |
d | 0.01 |
K_PEP | 0.08 |
Ki_GLY_b | 4.4 |
Keq_PGLM | 16.62 |
Ki_ADP | 0.135 |
Ki_Pi | 4.6 |
K_PYR | 7.05 |
K_F6P_ | 20.0 |
Keq_PK | 10304.0 |
K_three_PG | 0.2 |
Keq_PGI | 0.45 |
Keq_PGM | 0.18 |
K_GLY_f | 1.7 |
frac_a | 0.4 |
K_FBP_ | 4.02 |
nH | 1.75 |
Keq_TPI | 0.052 |
Ki_GLY_f | 15.0 |
K_GAP | 0.32 |
K_PCr | 1.11 |
K_ADP | 0.3 |
Lo | 13.0 |
K_ADP_ | 2.7 |
Keq_ADK | 2.21 |
K_NADH | 0.0033 |
Ka_AMP | 0.06 |
K_GLY_b | 0.15 |
K_Pi | 0.2 |
frac_b | 0.6 |
K_NAD | 0.09 |
K_two_PG | 0.014 |
V_ATPase | 600.0 |
Ki_PCr | 3.9 |
K_DHAP | 0.61 |
K_Cr | 3.8 |
Ki_G1P | 7.4 |
V_max_r | 880.0 |
K_LAC | 17.0 |
Keq_LDH | 16198.0 |
K_Thirteen_BPG | 0.0008 |
K_ATP | 1.13 |
Ki_ATP | 0.87 |
Keq_GP | 0.42 |
States:
| Name | Description |
|---|---|
PEP(time) | 0.0194 |
G6P(time) | 0.75 |
Pi(time) | 4.1 |
PCr(time) | 34.67 |
Cr(time) | 35.0 |
AMP(time) | 0.99 |
PYR(time) | 0.0994 |
two_PG(time) | 0.005 |
ATP(time) | 8.2 |
GAP(time) | 0.0355 |
F6P(time) | 0.228 |
Thirteen_BPG(time) | 0.065 |
NAD(time) | 0.5 |
LAC(time) | 1.3 |
DHAP(time) | 0.0764 |
FBP(time) | 0.0723 |
GLY(time) | 112.0 |
G1P(time) | 0.0589 |
three_PG(time) | 0.052 |
ADP(time) | 0.013 |
NADH(time) | 0.001 |
Land_et_al_2012 — v0.0.1Land et al. 2012
Details
Land et al 2012
Parameters:
| Name | Description |
|---|---|
T_ref | 120.0 |
k_xb | 0.1 |
Ca_50ref | 0.8 |
perm50 | 0.35 |
n_TRPN | 2.0 |
nperm | 5.0 |
alpha_1 | 0.1 |
A_1 | -29.0 |
a | 0.35 |
beta_1 | -1.5 |
alpha_2 | 0.5 |
k_off | 0.1 |
A_2 | 116.0 |
beta_0 | 1.65 |
States:
| Name | Description |
|---|---|
xb(time) | 0.00046 |
Q_2(time) | 0.0 |
TRPN(time) | 0.0752 |
Q_1(time) | 0.0 |
landesberg_sideman_1994 — v0.0.1Landesberg, Sideman, 1994
Details
Parameters:
| Name | Description |
|---|---|
f | nothing |
TRo | nothing |
L_b | nothing |
F_bar | nothing |
k_minus_h | nothing |
K_mu | nothing |
Ca_r | nothing |
d_alpha_dt | nothing |
B | nothing |
Q_u | nothing |
g_0 | nothing |
Troponin | nothing |
I_l | nothing |
SL | nothing |
Ca_0 | nothing |
L_a | nothing |
Q_i | nothing |
T_s | nothing |
tau_iR | nothing |
k_h | nothing |
Q_o | nothing |
tau_iF | nothing |
alpha | nothing |
U_s | nothing |
eta_PE | nothing |
Sp_0 | nothing |
D | nothing |
g_1 | nothing |
eta | nothing |
E | nothing |
Q_s | nothing |
L_z | nothing |
tau_SR | nothing |
tau_SF | nothing |
K_max | nothing |
L_prime_m | nothing |
k_1 | nothing |
States:
| Name | Description |
|---|---|
U_s(time) | nothing |
Ubar_d(time) | nothing |
Tbar_s(time) | nothing |
A_n(time) | nothing |
Tbar_d(time) | nothing |
Ubar_s(time) | nothing |
Abar_d(time) | nothing |
Rbar_s(time) | nothing |
Abar_s(time) | nothing |
Ca(time) | nothing |
Rbar_d(time) | nothing |
T_s(time) | nothing |
R_s(time) | nothing |
A_s(time) | nothing |
BCa_h(time) | nothing |
larsen_olsen_kummer_2003 — v0.0.1On the encoding and decoding of calcium signals in hepatocytes
Details
Many different agonists use calcium as a second messenger. Despite intensive research in intracellular calcium signalling it is an unsolved riddle how the different types of information represented by the different agonists, is encoded using the universal carrier calcium. It is also still not clear how the information encoded is decoded again into the intracellular specific information at the site of enzymes and genes. After the discovery of calcium oscillations, one likely mechanism is that information is encoded in the frequency, amplitude and waveform of the oscillations. This hypothesis has received some experimental support. However, the mechanism of decoding of oscillatory signals is still not known. Here, we study a mechanistic model of calcium oscillations, which is able to reproduce both spiking and bursting calcium oscillations. We use the model to study the decoding of calcium signals on the basis of co-operativity of calcium binding to various proteins. We show that this co-operativity offers a simple way to decode different calcium dynamics into different enzyme activities.
Parameters:
| Name | Description |
|---|---|
K19 | 3.5 |
k20 | 0.81 |
k14 | 153.0 |
K_M | 0.62 |
k18 | 79.0 |
k10 | 0.7 |
K11 | 3.0 |
k13 | 13.4 |
K15 | 0.16 |
k_rem | 3.0 |
p | 4.0 |
k8 | 32.24 |
K21 | 4.5 |
K17 | 0.05 |
K9 | 29.09 |
k12 | 2.8 |
k16 | 7.0 |
k_enz | 3.0 |
k1 | 0.01 |
K4 | 0.09 |
k_inact | 0.04 |
k_act | 5.0 |
k3 | 0.64 |
k7 | 2.08 |
k5 | 4.88 |
k2 | 1.75 |
K6 | 1.18 |
States:
| Name | Description |
|---|---|
PLC(time) | 0.01 |
Ca_ER(time) | 10.0 |
Enz(time) | 0.0 |
Ca_cyt(time) | 0.01 |
Pro(time) | 0.0 |
Ca_mit(time) | 0.001 |
G_a(time) | 0.01 |
lebeau_robson_mckinnon_donald_sneyd_1997 — v0.0.1Lebeau, Robson, Mckinnon, Donald, Sneyd, 1997
Details
Parameters:
| Name | Description |
|---|---|
i_CaT | nothing |
f | nothing |
Cai | nothing |
T | nothing |
vp | nothing |
g_K_Ca | nothing |
tau | nothing |
Cae | nothing |
Ki | nothing |
i_K_Ca | nothing |
Cm | nothing |
tau_h | nothing |
tau_n | nothing |
E_L | nothing |
alpha | nothing |
Ke | nothing |
Kp | nothing |
KC | nothing |
g_L | nothing |
beta | nothing |
g_CaT | nothing |
g_K_DR | nothing |
i_K_DR | nothing |
g_CaL | nothing |
Ca_eq | nothing |
tau_m_ | nothing |
R | nothing |
i_Leak | nothing |
F | nothing |
States:
| Name | Description |
|---|---|
V(time) | nothing |
n(time) | nothing |
m(time) | nothing |
h(time) | nothing |
lebeau_yule_groblewski_sneyd_1999 — v0.0.1Lebeau, Yule, Groblewski, Sneyd, 1999
Details
Parameters:
| Name | Description |
|---|---|
k2 | 0.5 |
alpha_1 | 40.0 |
beta_4 | 0.01 |
K_p | 0.54 |
k_flux | 28.0 |
alpha_4 | 0.06 |
beta_1 | 0.8 |
k3 | 0.5 |
V_p | 2.6 |
k5 | 0.02 |
J_influx | 0.4 |
k1_ | 0.88 |
p | 3.0 |
States:
| Name | Description |
|---|---|
O(time) | nothing |
I2(time) | nothing |
c(time) | nothing |
I1(time) | nothing |
leloup_goldbeter_1998 — v0.0.1Leloup, Goldbeter, 1998
Details
A Model for Circadian Rhythms in Drosophila Incorporating the Formation of a Complex between the PER and TIM proteins
Parameters:
| Name | Description |
|---|---|
n | 4.0 |
V_3 | 8.0 |
k_1 | 1.2 |
V_4P | 1.0 |
K_1T | 2.0 |
T_1init | 0.8 |
K_mT | 0.2 |
K_3 | 2.0 |
K_3T | 2.0 |
v_sT | 1.0 |
K_IT | 1.0 |
Y_1init | 0.8 |
V_1 | 8.0 |
k_2 | 0.2 |
V_4T | 1.0 |
v_dT | 2.0 |
K_2 | 2.0 |
V_4 | 1.0 |
k_d | 0.01 |
V_2 | 1.0 |
v_d | 2.0 |
M_Tinit | 1.427 |
V_1P | 8.0 |
k_3 | 1.2 |
v_mT | 0.7 |
k_sP | 0.9 |
P_2init | 0.01251 |
K_1 | 2.0 |
K_4P | 2.0 |
V_2T | 1.0 |
K_1P | 2.0 |
k_sT | 0.9 |
V_3T | 8.0 |
k_dN | 0.01 |
Y_0init | 0.02324 |
M_Pinit | 0.09107 |
T_2init | 4.733 |
Y_2init | 4.733 |
k_4 | 0.6 |
k_s | 0.9 |
K_d | 0.2 |
K_dP | 0.2 |
T_0init | 0.542 |
K_2T | 2.0 |
K_4 | 2.0 |
v_dT_dark | 2.0 |
K_mP | 0.2 |
K_m | 0.2 |
V_1T | 8.0 |
V_2P | 1.0 |
P_1init | 0.0221 |
K_I | 1.0 |
P_0init | 0.02324 |
v_s | 0.8 |
K_dT | 0.2 |
v_dP | 2.0 |
v_dT_light | 4.0 |
k_dC | 0.01 |
PI | 3.141592653589793 |
K_4T | 2.0 |
V_3P | 8.0 |
K_3P | 2.0 |
K_2P | 2.0 |
M_init | 0.09107 |
v_sP | 0.8 |
v_m | 0.8 |
K_IP | 1.0 |
v_mP | 0.8 |
States:
| Name | Description |
|---|---|
C_N(time) | 1.203 |
P_0(time) | 0.02324 |
P_2(time) | 0.01251 |
T_1(time) | 0.8 |
M(time) | 0.09107 |
Y_0(time) | 0.02324 |
C(time) | 0.179 |
T_0(time) | 0.542 |
Y_2(time) | 4.733 |
Y_1(time) | 0.8 |
T_2(time) | 4.733 |
P_1(time) | 0.0221 |
M_T(time) | 1.427 |
M_P(time) | 0.09107 |
leloup_goldbeter_2003 — v0.0.1Leloup, Goldbeter, 2003
Details
Parameters:
| Name | Description |
|---|---|
KmB | 0.4 |
PCNP_init | 0.1 |
Km | 0.4 |
MR_init | 1.5 |
V1 | 1.4 |
kdmr | 0.02 |
V2PC | 0.2 |
kdnc | 0.02 |
IN_init | 0.1 |
CC_init | 0.1 |
MC_init | 1.2 |
ke | 0.2 |
ksC | 3.2 |
vdPCN | 1.4 |
k3 | 0.8 |
BC_init | 0.1 |
vdRC | 4.4 |
V3PC | 2.4 |
vdCC | 1.4 |
ka | 0.4 |
vmB | 1.3 |
KmP | 0.3 |
PCP_init | 0.1 |
vsP | 2.4 |
MP_init | 0.1 |
Kd | 0.3 |
k6 | 0.4 |
ks | 1.2 |
vdPCC | 1.4 |
V2C | 0.2 |
V4B | 0.4 |
kdmb | 0.02 |
V1P | 9.6 |
Y_init | 0.1 |
vmR | 1.6 |
ksB | 0.32 |
m | 2.0 |
vm | 2.0 |
M_init | 1.2 |
MB_init | 9.0 |
k2 | 0.4 |
n | 2.0 |
vdBC | 3.0 |
PCN_init | 0.1 |
ksR | 1.7 |
c | 2.0 |
k9 | 0.8 |
vdIN | 1.6 |
k8 | 0.2 |
V2P | 0.6 |
V3B | 1.4 |
V4PC | 0.2 |
B | 0.6 |
vdRN | 0.8 |
vmP | 2.2 |
V1C | 1.2 |
KmC | 0.4 |
KAP | 0.6 |
YCP_init | 0.1 |
kc | 1.0 |
V1B | 1.4 |
kdn | 0.02 |
KAC | 0.6 |
vmC | 2.0 |
V1PC | 2.4 |
kd | 0.02 |
BCP_init | 0.1 |
KAR | 0.6 |
vsC | 2.2 |
KmR | 0.4 |
vsB | 1.8 |
YC_init | 0.1 |
PC_init | 0.1 |
k10 | 0.4 |
kdmp | 0.02 |
one | 1.0 |
ksP | 1.2 |
h | 2.0 |
V2B | 0.2 |
kdm | 0.02 |
kdmc | 0.02 |
Kdp | 0.1 |
k4 | 0.4 |
V2 | 0.2 |
kb | 0.8 |
vdPC | 3.4 |
vs | 2.2 |
A | 2.2 |
PCCP_init | 0.1 |
BN_init | 0.1 |
Kp | 1.006 |
PCC_init | 0.1 |
vd | 3.0 |
k1 | 0.8 |
BNP_init | 0.1 |
vsR | 1.6 |
CCP_init | 0.1 |
KIB | 2.2 |
k7 | 1.0 |
RN_init | 0.1 |
vdBN | 3.0 |
k5 | 0.8 |
States:
| Name | Description |
|---|---|
IN(time) | 0.1 |
PCNP(time) | 0.1 |
PCCP(time) | 0.1 |
YC(time) | 0.1 |
PCN(time) | 0.1 |
PCC(time) | 0.1 |
MB(time) | 9.0 |
MC(time) | 1.2 |
BC(time) | 0.1 |
BN(time) | 0.1 |
PC(time) | 0.1 |
MR(time) | 1.5 |
M(time) | 1.2 |
BCP(time) | 0.1 |
CCP(time) | 0.1 |
MP(time) | 0.1 |
RC(time) | 0.1 |
RN(time) | 0.1 |
CC(time) | 0.1 |
PCP(time) | 0.1 |
YCP(time) | 0.1 |
Y(time) | 0.1 |
BNP(time) | 0.1 |
leloup_goldbeter_2004 — v0.0.1Leloup, Goldbeter, 2004
Details
Parameters:
| Name | Description |
|---|---|
vdBC | 1.0 |
PCN_init | 0.1 |
c | 4.0 |
vdIN | 0.8 |
KmB | 0.4 |
PCNP_init | 0.1 |
Km | 0.4 |
k8 | 0.1 |
V2PC | 0.1 |
V1 | 1.0 |
V2P | 0.3 |
V3B | 1.0 |
kdnc | 0.01 |
IN_init | 0.1 |
V4PC | 0.1 |
vstot | 1.0 |
vmP | 1.1 |
B | 1.0 |
V1C | 0.6 |
CC_init | 0.1 |
KmC | 0.4 |
KAP | 0.7 |
YCP_init | 0.1 |
MC_init | 0.3 |
kc | 0.5 |
V1B | 1.0 |
kdn | 0.01 |
KAC | 1.0 |
ke | 0.1 |
vdPCN | 1.0 |
vmC | 1.0 |
kd | 0.01 |
BCP_init | 0.1 |
k3 | 0.8 |
BC_init | 0.1 |
kstot | 1.0 |
YC_init | 0.1 |
vdCC | 0.7 |
ka | 0.2 |
Vphos | 0.6 |
vmB | 0.2 |
PC_init | 0.1 |
KmP | 0.3 |
PCP_init | 0.1 |
kdmp | 0.01 |
V2B | 0.1 |
kdm | 0.01 |
kdmc | 0.01 |
Kdp | 0.3 |
k4 | 0.2 |
V2 | 0.1 |
kb | 0.8 |
MP_init | 0.5 |
Kd | 0.3 |
k6 | 0.2 |
vdPC | 0.7 |
vdPCC | 1.0 |
V2C | 0.1 |
V4B | 0.2 |
A | 0.8 |
PCCP_init | 0.1 |
BN_init | 0.1 |
Kp | 0.1 |
PCC_init | 0.1 |
vd | 1.0 |
k1 | 0.8 |
kdmb | 0.01 |
BNP_init | 0.1 |
Y_init | 0.1 |
m | 4.0 |
CCP_init | 0.1 |
KIB | 0.8 |
vm | 1.0 |
MB_init | 3.1 |
M_init | 0.3 |
k7 | 0.5 |
vdBN | 0.5 |
k5 | 0.4 |
k2 | 0.2 |
n | 4.0 |
States:
| Name | Description |
|---|---|
IN(time) | 0.1 |
BC(time) | 0.1 |
PCNP(time) | 0.1 |
M(time) | 0.3 |
PCCP(time) | 0.1 |
PC(time) | 0.1 |
BN(time) | 0.1 |
YC(time) | 0.1 |
BCP(time) | 0.1 |
YCP(time) | 0.1 |
CCP(time) | 0.1 |
MP(time) | 0.5 |
PCN(time) | 0.1 |
CC(time) | 0.1 |
PCP(time) | 0.1 |
PCC(time) | 0.1 |
Y(time) | 0.1 |
MB(time) | 3.1 |
MC(time) | 0.3 |
BNP(time) | 0.1 |
leloup_gonze_goldbeter_1999 — v0.0.1Leloup, Gonze, Goldbeter, 1999
Details
Parameters:
| Name | Description |
|---|---|
KIT | 1.0 |
ksT | 0.9 |
T1_init | 0.1 |
V3 | 8.0 |
K4T | 1.0 |
P2_init | 0.1 |
K3 | 2.0 |
V3P | 8.0 |
Km | 0.5 |
V1 | 8.0 |
K3T | 2.0 |
V2P | 1.0 |
KIP | 1.0 |
K2T | 2.0 |
KmT | 0.2 |
T2_init | 0.1 |
vmP | 0.7 |
V2T | 1.0 |
V4P | 1.0 |
vdT | 2.0 |
vdP | 2.0 |
K2P | 2.0 |
Y1_init | 0.1 |
kd | 0.01 |
K4 | 1.0 |
P0_init | 0.1 |
T0_init | 0.1 |
MT_init | 1.6 |
V1T | 8.0 |
k3 | 1.2 |
K3P | 2.0 |
V4T | 1.0 |
K1 | 2.0 |
K2 | 2.0 |
KmP | 0.2 |
V3T | 8.0 |
vsT | 1.0 |
ksP | 0.9 |
Y2_init | 0.1 |
k4 | 0.6 |
vsP | 1.0 |
V2 | 1.0 |
MP_init | 0.1 |
kdN | 0.01 |
Kd | 0.13 |
KI | 1.0 |
vmT | 0.7 |
KdT | 0.2 |
ks | 0.5 |
vs | 1.6 |
Y0_init | 0.1 |
K4P | 1.0 |
V4 | 1.0 |
vd | 1.4 |
KdP | 0.2 |
k1 | 0.5 |
V1P | 8.0 |
P1_init | 0.1 |
K1P | 2.0 |
vm | 0.505 |
M_init | 0.1 |
kdC | 0.01 |
K1T | 2.0 |
k2 | 0.6 |
n | 4.0 |
States:
| Name | Description |
|---|---|
T1(time) | 0.1 |
P0(time) | 0.1 |
FC(time) | 0.1 |
M(time) | 0.1 |
C(time) | 0.1 |
P1(time) | 0.1 |
T2(time) | 0.1 |
MT(time) | 1.6 |
MP(time) | 0.1 |
FN(time) | 0.1 |
Y1(time) | 0.1 |
P2(time) | 0.1 |
T0(time) | 0.1 |
CN(time) | 1.25 |
Y2(time) | 0.1 |
Y0(time) | 0.1 |
lemaire_tobin_greller_cho_suva_2004 — v0.0.1Lemaire, Tobin, Greller, Cho, Suva, 2004
Details
Parameters:
| Name | Description |
|---|---|
Io | 0.0 |
DC | 0.0021 |
ko | 0.35 |
f0 | 0.05 |
KOP | 200000.0 |
SP | 250.0 |
kB | 0.189 |
dB | 0.7 |
k4 | 0.017 |
DA | 0.7 |
k6 | 3.0 |
DR | 0.0007 |
IP | 0.0 |
k1 | 0.01 |
KLP | 3.0e6 |
kP | 86.0 |
C_s | 0.005 |
k3 | 0.00058 |
rL | 1000.0 |
K | 10.0 |
k5 | 0.02 |
k2 | 10.0 |
IL | 0.0 |
States:
| Name | Description |
|---|---|
R(time) | 0.0 |
C(time) | 0.0 |
B(time) | 0.0 |
lemon_gibson_bennett_2003 — v0.0.1Lemon, Gibson, Bennett, 2003
Details
Parameters:
| Name | Description |
|---|---|
eta_2 | 5.2 |
K_c | 0.4 |
epsilon_r | 0.185 |
N_a | 6.02252e17 |
L | 1000.0 |
a_2 | 0.2 |
delta | 0.001238 |
C_T | 67.0 |
K_e | 10.0 |
B_ER | 120000.0 |
B_x | 50.0 |
r_r | 10.0 |
G_T | 100000.0 |
eta_3 | 45.0 |
xi | 0.85 |
K_2 | 100.0 |
d_2 | 1.05 |
v | 5.0e-13 |
K_x | 0.2 |
k_d | 0.15 |
B_e | 150.0 |
alpha | 2.781e-5 |
k_deg | 1.25 |
k_a | 0.017 |
d_3 | 0.943 |
d_5 | 0.0823 |
k_3 | 0.4 |
eta_1 | 575.0 |
PIP_2_T | 5.0e7 |
d_1 | 0.13 |
R_T | 20000.0 |
K_1 | 5.0 |
k_e | 0.006 |
K_ER | 1200.0 |
k_r | 0.000175 |
k_p | 0.03 |
States:
| Name | Description |
|---|---|
PIP_2(time) | 4.9997e7 |
G(time) | 0.0 |
h(time) | 0.6155 |
RS_p(time) | 0.0 |
IP_3(time) | 0.01 |
RS(time) | 17000.0 |
C(time) | 0.0961 |
lenbury_pacheenburawana_1991 — v0.0.1Lenbury, Pacheenburawana, 1991
Details
Parameters:
| Name | Description |
|---|---|
omega | 2.0 |
alpha | 0.5 |
b | 1.091 |
gamma | 0.6 |
D | 0.8228 |
a | 8.1252 |
beta | 0.38 |
States:
| Name | Description |
|---|---|
x(time) | 1.5 |
y(time) | 0.95 |
z(time) | 1.0 |
lenbury_pornsawad_2005 — v0.0.1Lenbury, Pornsawad, 2005
Details
Parameters:
| Name | Description |
|---|---|
delta1 | 0.5 |
delta2 | 0.38 |
delta3 | 0.6 |
beta | 1.091 |
States:
| Name | Description |
|---|---|
x(time) | 1.0 |
y(time) | 0.01 |
z(time) | 0.01 |
lenbury_ruktamatakul_amornsamarnkul_2001 — v0.0.1Lenbury, Ruktamatakul, Amornsamarnkul, 2001
Details
Parameters:
| Name | Description |
|---|---|
c1 | 0.1 |
r5 | 0.09 |
r_2 | 0.1 |
delta | 0.01 |
r_4 | 0.1 |
r4 | 0.03 |
r_6 | 0.1 |
omega | 0.05 |
c_1 | 0.1 |
r_7 | 0.05 |
y_hat | 1.24 |
y_ | 1.08 |
c_2 | 0.1 |
r3 | 0.05 |
c2 | 0.1 |
r_5 | 0.1 |
r_1 | 0.2 |
r_3 | 0.1 |
z_ | 1.01 |
r7 | 0.05 |
r1 | 0.15 |
r2 | 0.12 |
z_hat | 2.0 |
epsilon | 0.1 |
c3 | 0.005 |
r6 | 0.1 |
States:
| Name | Description |
|---|---|
u(time) | 1.0 |
v(time) | 0.0 |
x(time) | 5.0 |
y(time) | 0.0 |
z(time) | 1.0 |
li_bertram_rinzel_1996 — v0.0.1Li, Bertram and Rinzel, 1996
Details
Parameters:
| Name | Description |
|---|---|
C_m | 1.0 |
k_Ca | 1.0 |
V_h | -30.0 |
g_K_Ca | 1.2 |
K_p | 15.0 |
R_pump | 18.0 |
V_K | -85.0 |
g_K_DR_D | 0.14 |
g_h | 0.1 |
K_Ca | 0.0004 |
V_NMDA | 0.0 |
V_Na | 55.0 |
g_K_DR_s | 6.4 |
q | 12.5 |
g_Na_s | 3.2 |
alpha | 0.5 |
K_Mg | 10.0 |
g_Na | 3.2 |
K_Na | 15.0 |
g_L | 0.18 |
V_L | -50.0 |
beta | 0.104 |
I_APP | -6.7 |
Na_eq | 8.0 |
g_NMDA | 1.25 |
V_Ca | 120.0 |
Mg_o | 1.4 |
g_Ca_T | 1.5 |
g_Ca_L | 0.19 |
g_K_DR | 3.2 |
g_Na_NMDA | 1.0 |
g_c | 0.0 |
g_A | 2.0 |
p | 0.5 |
States:
| Name | Description |
|---|---|
h(time) | 1.0 |
a(time) | 0.1 |
V_s(time) | -64.0 |
Na(time) | 5.09 |
m_L(time) | 0.1 |
h_T(time) | 0.1 |
Ca(time) | 0.0 |
b(time) | 0.1 |
m_h(time) | 0.1 |
n(time) | 0.002 |
V_D(time) | -25.0 |
m_T(time) | 0.1 |
li_kuang_mason_2006 — v0.0.1Li, Kuang, Mason, 2006
Details
Parameters:
| Name | Description |
|---|---|
C3 | 1000.0 |
Rm | 210.0 |
Gin | 0.54 |
a1 | 300.0 |
Ub | 72.0 |
alpha | 0.29 |
C4 | 80.0 |
di | 0.06 |
E | 0.2 |
Um | 940.0 |
beta | 1.77 |
C1 | 2000.0 |
C2 | 144.0 |
ti | 100.0 |
U0 | 40.0 |
Vp | 3.0 |
C5 | 26.0 |
Vg | 10.0 |
Rg | 180.0 |
Vi | 11.0 |
States:
| Name | Description |
|---|---|
G(time) | 1000.0 |
I(time) | 9000.0 |
li_rinzel_1994 — v0.0.1Li, Rinzel, 1994
Details
Parameters:
| Name | Description |
|---|---|
c1 | 0.185 |
v4 | 1.8 |
v1 | 40.0 |
d_inh | 0.4 |
k_er | 0.18 |
a | 1.0 |
d_act | 0.4 |
IP3 | 0.6 |
k_pl | 0.1 |
d_ip3 | 0.2 |
epsilon | 0.01 |
States:
| Name | Description |
|---|---|
j_in(time) | 1.2 |
h(time) | 0.8 |
v3(time) | 0.6 |
C(time) | 0.2 |
v2(time) | 0.02 |
c0(time) | 2.0 |
li_smith_2009 — v0.0.1Li, Smith, 2009
Details
Parameters:
| Name | Description |
|---|---|
const5 | 6.6755 |
T | 308.0 |
Km_CSQN | 800.0 |
delta_V_L | 7.0671 |
stim_offset | 100.0 |
P_ryr_const1 | -0.09 |
Km_Nai | 21000.0 |
k_plus_a | 0.006075 |
kf | 0.023761 |
Bmax | 109.0 |
Km_Cl | 10.0 |
Ko | 5400.0 |
i_NaK_max | 1.66 |
on_rate | 0.05 |
Cm | 1.0 |
K_L | 0.0964 |
vmup_init | 0.3158 |
E_Cl | -40.0 |
g_Kto_f | 0.4067 |
k_sat | 0.1 |
K_mNa | 86500.0 |
eta | 0.35 |
V_L | -2.0 |
g_Ks | 0.00575 |
g_K1 | 0.2938 |
i_CaL_max | 4.0 |
tau_tr | 20.0 |
g_Kr | 0.078 |
Acap | 0.00013866 |
K_mCa | 1380.0 |
Km_pCa | 0.4 |
P_ryr_const2 | -0.225 |
k_minus_a | 0.07125 |
P_CaL | 19.1078 |
stim_duration | 3.0 |
k_minus_b | 0.965 |
v1 | 4.5 |
i_pCa_max | 0.9 |
Cao | 1400.0 |
b | 14.0 |
Vmyo | 2.2e-5 |
g_Nab | 0.0026 |
tau_xfer | 8.0 |
Km_up | 0.412 |
g_Kto_s | 0.0 |
a | 0.07 |
Km_Ko | 1500.0 |
stim_period | 333.3333333 |
kb | 0.036778 |
Kd | 0.6 |
k_plus_b | 0.00405 |
CSQN_tot | 15000.0 |
off_rate | 0.00068 |
Nao | 134000.0 |
g_Na | 13.0 |
VJSR | 1.022e-7 |
k_plus_c | 0.009 |
g_Cab | 0.00088 |
stim_amplitude | -15.0 |
tau_L | 972.9715 |
g_ClCa | 10.0 |
VNSR | 1.786e-6 |
m | 3.0 |
phi_L | 1.6411 |
g_Kss | 0.05 |
v2 | 1.0e-5 |
k_minus_c | 0.0008 |
Vss | 1.264e-9 |
g_Kur | 0.16 |
k_NaCa | 772.8991 |
R | 8.314 |
t_L | 1.1683 |
F | 96.5 |
n | 4.0 |
States:
| Name | Description |
|---|---|
C_Na2(time) | 0.01702105 |
O_K(time) | 0.0004858865 |
I(time) | 0.009171979 |
O_Na(time) | 2.639399e-7 |
ato_f(time) | 0.001937245 |
P_C2(time) | 0.3797679 |
I2_Na(time) | 5.460299e-6 |
C_K2(time) | 0.0005301217 |
O(time) | 4.373318e-6 |
IC_Na2(time) | 0.005985434 |
C_Na1(time) | 0.0001581035 |
P_RyR(time) | 2.290355e-9 |
ito_f(time) | 0.9999985 |
nKs(time) | 0.002206261 |
I1_Na(time) | 1.799179e-5 |
Nai(time) | 16522.45 |
Cass(time) | 0.1043777 |
y_gate(time) | 0.8876797 |
IC_Na3(time) | 0.2543133 |
ato_s(time) | 0.02000568 |
V(time) | -85.64004 |
IF_Na(time) | 5.56206e-5 |
CaJSR(time) | 730.0589 |
C_K1(time) | 0.0007799137 |
CaMKt(time) | 0.08989079 |
aur(time) | 0.02000568 |
iur(time) | 0.9822006 |
iKss(time) | 1.0 |
P_O1(time) | 0.003825599 |
Ki(time) | 141474.0 |
I_K(time) | 7.519518e-5 |
CaNSR(time) | 841.106 |
ito_s(time) | 0.9308568 |
Cai(time) | 0.1040595 |
P_O2(time) | 1.835831e-8 |
aKss(time) | 0.8883113 |
lindblad_murphey_clark_giles_1996 — v0.0.1Lindblad, Murphey, Clark, Giles, 1996
Details
Parameters:
| Name | Description |
|---|---|
KmK1 | 0.59 |
T | 308.0 |
stim_start | 0.1 |
P_Na | 1.4e-6 |
Mg_i | 2.5 |
d_NaCa | 0.0003 |
alpha_rel | 200.0 |
k_NaK_K | 1.0 |
i_NaK_max | 0.06441 |
I_up_max | 2.8 |
g_to | 0.050002 |
g_B_Cl | 0.00012 |
k_CaP | 0.0002 |
Cm | 5.0e-5 |
shiftK1 | -3.6 |
Ca_c | 2.5 |
Vol_rel | 4.41e-8 |
Vol_i | 1.26e-5 |
k_rel | 0.0003 |
Cl_c | 132.0 |
Vol_up | 3.969e-7 |
g_Ks | 0.0025 |
g_K1 | 0.005088 |
k_xcs | 0.4 |
tau_tr | 0.01 |
g_Kr | 0.0035 |
g_Ca_L | 0.004 |
steepK1 | 1.393 |
stim_duration | 0.0008 |
K_c | 5.0 |
Na_c | 140.0 |
g_B_Na | 6.4e-5 |
E_Ca_T | 38.0 |
stim_period | 1.0 |
stim_end | 100000.0 |
k_NaK_Na | 11.0 |
k_srca | 0.5 |
Cl_i | 30.0 |
i_CaP_max | 0.009509 |
g_B_Ca | 3.1e-5 |
stim_amplitude | -2.0 |
k_cyca | 0.0003 |
Vol_Ca | 5.884e-6 |
E_Ca_app | 60.0 |
g_Ca_T | 0.006 |
gamma | 0.45 |
k_NaCa | 2.0e-5 |
k_F3 | 0.815 |
R | 8314.472 |
F | 96485.3415 |
States:
| Name | Description |
|---|---|
O_TC(time) | 0.01442 |
F3(time) | 0.68492 |
s2(time) | 0.39871 |
O_Calse(time) | 0.41837 |
f_T(time) | 0.30752 |
s3(time) | 0.57363 |
d_L(time) | 3.0e-5 |
s1(time) | 0.5753 |
m(time) | 0.01309 |
Na_i(time) | 8.4 |
O_C(time) | 0.02981 |
d_T(time) | 0.00046 |
Ca_rel(time) | 0.59984 |
h2(time) | 0.61493 |
O_TMgMg(time) | 0.67476 |
V(time) | -69.83663 |
p_i(time) | 0.76898 |
p_a(time) | 0.00016 |
z(time) | 0.02032 |
K_i(time) | 100.0 |
r(time) | 6.0e-5 |
F1(time) | 0.21603 |
f_L(time) | 0.99981 |
h1(time) | 0.706 |
Ca_up(time) | 0.64913 |
Ca_i(time) | 7.305e-5 |
F2(time) | 0.00205 |
O_TMgC(time) | 0.23532 |
liu_hu_peng_liu_1999 — v0.0.1Liu, Hu, Peng, Liu, 1999
Details
Parameters:
| Name | Description |
|---|---|
a21 | 200.0 |
a13 | 460.0 |
a2 | 0.0023 |
a1 | 1.7e-5 |
lambda_1 | 0.059 |
a15 | 0.1 |
a22 | 9400.0 |
a18 | 3800.0 |
a7 | 0.28 |
a12 | 18.0 |
lambda_3 | 0.0986 |
a5 | 36.0 |
a19 | 57.0 |
a27 | 0.57 |
a3 | 0.6 |
lambda_5 | 3.0e-5 |
lambda_4 | 0.024 |
a14 | 0.46 |
a4 | 45.0 |
a6 | 216.0 |
lambda_2 | 0.028 |
a10 | 0.18 |
a8 | 0.36 |
a11 | 150.0 |
a17 | 150.0 |
a23 | 10.0 |
a25 | 0.04 |
a26 | 0.00097 |
a16 | 0.04 |
a9 | 0.0003 |
a20 | 2600.0 |
a28 | 0.0017 |
a24 | 320.0 |
States:
| Name | Description |
|---|---|
x4(time) | 60.61 |
x3(time) | 6.51 |
x5(time) | 12.61 |
x2(time) | 0.04665 |
x1(time) | 0.01067 |
livervolume — v0.0.1Volume mesh of liver
Details
livshitz_rudy_2007 — v0.0.1Livshitz, Rudy, 2007
Details
Parameters:
| Name | Description |
|---|---|
prnak | 0.01833 |
GNa | 16.0 |
qn | 9.0 |
gcab | 0.003016 |
ganai | 0.75 |
GKsmax | 0.433 |
iupbar | 0.00875 |
tau | 4.75 |
Temp | 310.0 |
pk | 1.93e-7 |
stim_offset | 0.0 |
kmup | 0.00092 |
ibarpca | 1.15 |
tautr | 120.0 |
kmko | 1.5 |
GKpmax | 0.00552 |
kmpca | 0.0005 |
c2 | 0.0001 |
K_Relss | 1.0 |
l | 0.01 |
trpnbar | 0.07 |
gako | 0.75 |
kmtrpn | 0.0005 |
c1 | 0.00025 |
Na_o | 140.0 |
nsrbar | 15.0 |
stim_duration | 3.0 |
ibarnak | 2.25 |
csqnbar | 10.0 |
Ca_o | 1.8 |
stim_period | 400.0 |
kmcmdn | 0.00238 |
pna | 6.75e-7 |
kappa | 0.125 |
gacai | 1.0 |
K_o | 4.5 |
ganao | 0.75 |
gacao | 0.341 |
ra | 0.0011 |
GNab | 0.004 |
kmnai | 10.0 |
GK1max | 0.75 |
gcat | 0.05 |
kmca | 0.0006 |
kmcsqn | 0.8 |
pca | 0.00054 |
stim_amplitude | -15.0 |
gammas | 0.15 |
gaki | 0.75 |
R | 8314.0 |
cmdnbar | 0.05 |
F | 96485.0 |
gkrmax | 0.02614 |
States:
| Name | Description |
|---|---|
d(time) | 3.2514786721066e-27 |
g(time) | 0.952834331760863 |
xr(time) | 0.000162194715543637 |
Ca_JSR_T(time) | 7.87371650296567 |
Ca_NSR(time) | 2.71518235696672 |
V(time) | -89.4356034692784 |
f(time) | 0.997404948824816 |
K_i(time) | 139.730914103161 |
J(time) | 0.996100688673679 |
Rel(time) | 1.06874246141923e-23 |
Over(time) | 1.0e-12 |
xs1(time) | 0.0285147332973946 |
b(time) | 0.000927461915392873 |
H(time) | 0.994401369032678 |
Ca_T(time) | 0.0257059808595638 |
m(time) | 0.000734780346592185 |
xs2(time) | 0.0764114040188678 |
Na_i(time) | 16.612739313555 |
lockwood_ewy_hermann_holford_2006 — v0.0.1Lockwood, Ewy, Hermann, Holford, 2006
Details
Application of Clinical Trial Simulation to Compare Proof-of-Concept Study Designs for Drugs with a Slow Onset of Effect; An Example in Alzheimer’s Disease
Parameters:
| Name | Description |
|---|---|
t_half_eq_p | 6.0 |
t_half_el_p | 7.0 |
alpha | 0.0164 |
beta_a | -0.047 |
k_ab | 115.44 |
CL_ic | 763.2 |
age | 40.0 |
S0 | 30.0 |
epsilon | 0.0 |
beta_P | -3.0 |
Vp | 222.0 |
CeA | 25.0 |
smk | 1.0 |
Vc | 172.0 |
States:
| Name | Description |
|---|---|
CC(time) | 0.0 |
PC(time) | 0.0 |
A_in(time) | 25.0 |
lokta_volterra — v0.0.1Lokta, Volterra
Details
Predator-prey equations
Parameters:
| Name | Description |
|---|---|
B | 1.0 |
A | 1.0 |
C | 1.0 |
D | 1.0 |
States:
| Name | Description |
|---|---|
x(t) | 3.0 |
y(t) | 6.0 |
Lorenz_1963 — v0.0.1Deterministic Nonperiodic Flow
Details
The Lorenz attractor, named for Edward N. Lorenz, is an example of a non-linear dynamic system corresponding to the long-term behavior of the Lorenz oscillator. The Lorenz oscillator is a 3-dimensional dynamical system that exhibits chaotic flow, noted for its lemniscate shape. The map shows how the state of a dynamical system (the three variables of a three-dimensional system) evolves over time in a complex, non-repeating pattern.
States:
| Name | Description |
|---|---|
z(t) | 1.05 |
x(t) | 0.0 |
y(t) | 1.0 |
lovell_cloherty_celler_dokos_2004 — v0.0.1Lovell, Cloherty, Celler, Dokos, 2004
Details
Parameters:
| Name | Description |
|---|---|
K3ni | nothing |
PKNa_s | nothing |
beta1_Eslope | nothing |
T | nothing |
beta4_0 | nothing |
g_bCl | nothing |
alpha2_Eslope | nothing |
beta2_0 | nothing |
Iup_max | nothing |
beta1_0 | nothing |
alpha4_0 | nothing |
beta4_infinity | nothing |
Vup | nothing |
K1ni | nothing |
PKNa_r | nothing |
alpha3_infinity | nothing |
Ve | nothing |
Cab | nothing |
alpha3_Eslope | nothing |
g_f_K | nothing |
beta3_Eslope | nothing |
Kb | nothing |
beta3 | nothing |
P_f_K | nothing |
g_to | nothing |
Kcni | nothing |
Cm | nothing |
beta2_E50 | nothing |
beta4 | nothing |
Qco | nothing |
alpha3_E50 | nothing |
beta1_E50 | nothing |
beta4_Eslope | nothing |
alpha2_0 | nothing |
alpha1_infinity | nothing |
Kco | nothing |
g_Ks | nothing |
alpha2_infinity | nothing |
alpha4_Eslope | nothing |
alpha1_Eslope | nothing |
tau_b | nothing |
g_Kr | nothing |
Km_Caup | nothing |
tau_tr | nothing |
alpha4_E50 | nothing |
alpha1_E50 | nothing |
alpha3_0 | nothing |
Km_Na | nothing |
tau_rel | nothing |
beta3_E50 | nothing |
K1no | nothing |
Clb | nothing |
alpha1_0 | nothing |
beta3_infinity | nothing |
Km_f | nothing |
K2no | nothing |
Qn | nothing |
Nab | nothing |
Km_Carel | nothing |
beta2_infinity | nothing |
beta3_0 | nothing |
beta4_E50 | nothing |
K3no | nothing |
alpha3 | nothing |
K2ni | nothing |
Vi | nothing |
Qci | nothing |
Kci | nothing |
g_Na | nothing |
alpha4 | nothing |
alpha2_E50 | nothing |
g_f_Na | nothing |
beta2_Eslope | nothing |
kNaCa | nothing |
g_CaT | nothing |
Km_K | nothing |
Ip_max | nothing |
g_CaL | nothing |
alpha4_infinity | nothing |
beta1_infinity | nothing |
R | nothing |
Vrel | nothing |
F | nothing |
Kb_K | nothing |
States:
| Name | Description |
|---|---|
Caup(time) | nothing |
A_Kr(time) | nothing |
Em(time) | nothing |
A_to(time) | nothing |
Cli(time) | nothing |
A_CaL(time) | nothing |
Cao(time) | nothing |
A_f(time) | nothing |
Clo(time) | nothing |
Ko(time) | nothing |
A_Ks(time) | nothing |
I2(time) | nothing |
Ki(time) | nothing |
A_CaT(time) | nothing |
I3(time) | nothing |
Cai(time) | nothing |
Nai(time) | nothing |
Carel(time) | nothing |
A_Na(time) | nothing |
I1(time) | nothing |
Nao(time) | nothing |
luo_rudy_1991 — v0.0.1Luo, Rudy, 1991
Details
Parameters:
| Name | Description |
|---|---|
g_b | 0.03921 |
stim_duration | 2.0 |
T | 310.0 |
C | 1.0 |
stim_start | 100.0 |
Nao | 140.0 |
g_Na | 23.0 |
PR_NaK | 0.01833 |
E_b | -59.87 |
g_Kp | 0.0183 |
Ki | 145.0 |
stim_end | 9000.0 |
stim_period | 1000.0 |
Nai | 18.0 |
stim_amplitude | -25.5 |
Ko | 5.4 |
R | 8314.0 |
F | 96484.6 |
States:
| Name | Description |
|---|---|
d(time) | 0.00302126301779861 |
j(time) | 0.989108212766685 |
V(time) | -84.3801107371 |
h(time) | 0.982660523699656 |
X(time) | 0.0417603108167287 |
m(time) | 0.00171338077730188 |
Cai(time) | 0.00017948816388306 |
f(time) | 0.999967936476325 |
luo_rudy_1994 — v0.0.1Luo, Rudy, 1994
Details
Parameters:
| Name | Description |
|---|---|
gamma_Cai | 1.0 |
gamma_Cao | 0.34 |
T | 310.0 |
P_Na | 6.75e-9 |
Km_Ca | 0.0006 |
delta_Ca_i2 | 0.0 |
K_mup | 0.00092 |
G_rel_max | 60.0 |
delta_Ca_ith | 0.00018 |
K_sat | 0.1 |
Ko | 5.4 |
gamma_Nao | 0.75 |
tau_on | 2.0 |
Cm | 0.01 |
stimCurrent | 0.5 |
stimDuration | 0.5 |
P_ns_Ca | 1.75e-9 |
V_NSR | 0.0552 |
Am | 200.0 |
PR_NaK | 0.01833 |
K_mNa | 87.5 |
eta | 0.35 |
V_myo | 0.68 |
tau_tr | 180.0 |
Ca_NSR_max | 15.0 |
g_K_max | 0.00282 |
K_mCa | 1.38 |
g_K1_max | 0.0075 |
Cao | 1.8 |
g_Nab | 1.41e-5 |
t_CICR | 0.0 |
gamma_Nai | 0.75 |
K_mpCa | 0.0005 |
V_JSR | 0.0048 |
gamma_Ki | 0.75 |
K_m_ns_Ca | 0.0012 |
tau_off | 2.0 |
I_pCa | 0.0115 |
I_NaK | 0.015 |
Nao | 140.0 |
K_mNai | 10.0 |
P_Ca | 5.4e-6 |
g_Na | 0.16 |
stimPeriod | 1000.0 |
I_up | 0.005 |
g_Cab | 3.016e-5 |
g_Kp | 0.000183 |
K_mrel | 0.0008 |
gamma_Ko | 0.75 |
K_NaCa | 20.0 |
K_mKo | 1.5 |
R | 8314.5 |
P_K | 1.93e-9 |
F | 96845.0 |
States:
| Name | Description |
|---|---|
d(time) | 0.0 |
V(time) | -84.624 |
X(time) | 0.0 |
Ca_NSR(time) | 1.8 |
h(time) | 1.0 |
f(time) | 1.0 |
Ca_JSR(time) | 1.8 |
Ki(time) | 145.0 |
j(time) | 1.0 |
m(time) | 0.0 |
Cai(time) | 0.00012 |
Nai(time) | 10.0 |
M
macgregor_leng_2005 — v0.0.1Macgregor, Leng, 2005
Details
Parameters:
| Name | Description |
|---|---|
delta_r | 0.2 |
c | 0.01 |
Ise | 10.0 |
theta_3 | 30.0 |
Is2 | 50.0 |
theta_1 | 1.0 |
n1 | 4.0 |
k8 | 0.07 |
theta_2 | 30.0 |
delta | 60.0 |
sr | -0.56 |
k4 | 0.5 |
sb | 0.029 |
g2 | 0.008 |
k6 | 5.0 |
n3 | 5.0 |
g1 | 1.0 |
j1 | 10.0 |
gmax | 5.0 |
k1 | 0.1 |
Ih | 50.0 |
n2 | 2.0 |
delta1 | 15.0 |
k3 | 0.018 |
delta_b | 0.3 |
k7 | 5.0 |
k5 | 71.0 |
k2 | 0.002 |
States:
| Name | Description |
|---|---|
hh(time) | 0.0 |
g(time) | 2.0 |
r(time) | 0.0 |
h(time) | 0.0 |
s(time) | 0.0 |
f(time) | 0.3 |
se(time) | 0.0 |
mackenzie_loo_panayotova_heiermann_wright_1996 — v0.0.1Mackenzie, Loo, Panayotova-Heiermann and Wright, 1996
Details
magnus_keizer_1997 — v0.0.1Magnus, Keizer, 1997
Details
Parameters:
| Name | Description |
|---|---|
pH_m | nothing |
na | nothing |
f | nothing |
rb | nothing |
Jmax_ant | nothing |
T | nothing |
Na_i | nothing |
Ca_i | nothing |
L | nothing |
pb | nothing |
K_Ca | nothing |
Jmax_uni | nothing |
pH_i | nothing |
ATP_m | nothing |
pa | nothing |
g | nothing |
Cmito | nothing |
g_H | nothing |
pc2 | nothing |
ATP_i | nothing |
r2 | nothing |
ADP_i | nothing |
pc1 | nothing |
rho_F1 | nothing |
p2 | nothing |
p1 | nothing |
rc2 | nothing |
p3 | nothing |
V_offset | nothing |
b | nothing |
fm | nothing |
K_trans | nothing |
ra | nothing |
rho_res | nothing |
r3 | nothing |
V_B | nothing |
NAD_m | nothing |
K_res | nothing |
Jmax_Na_Ca | nothing |
Pi_m | nothing |
K_Na | nothing |
NADH_m | nothing |
K_act | nothing |
r1 | nothing |
K_F1 | nothing |
rc1 | nothing |
R | nothing |
F | nothing |
n | nothing |
States:
| Name | Description |
|---|---|
V(time) | nothing |
Ca_m(time) | nothing |
ADP_m(time) | nothing |
magnus_keizer_1998 — v0.0.1Magnus, Keizer, 1998
Details
Parameters:
| Name | Description |
|---|---|
K_tt | nothing |
na | nothing |
k_Ca | nothing |
C | nothing |
V_K | nothing |
K_Ca | nothing |
Jmax_ANT | nothing |
beta3 | nothing |
ATP_m | nothing |
beta6 | nothing |
K_dd | nothing |
g_H | nothing |
pc2 | nothing |
Jmax_NaCa | nothing |
k_minus_2 | nothing |
g_K_ATP | nothing |
K_td | nothing |
r2 | nothing |
glu | nothing |
Tmin | nothing |
rho_F1 | nothing |
p1 | nothing |
pc1 | nothing |
n_hyd | nothing |
ATP_m_free | nothing |
tau_hyd | nothing |
p3 | nothing |
b | nothing |
K_trans | nothing |
beta7 | nothing |
beta1 | nothing |
r3 | nothing |
k_hyd | nothing |
k_plus_2 | nothing |
alpha | nothing |
K_res | nothing |
gamma2 | nothing |
beta5 | nothing |
Jp_TCA | nothing |
f_i | nothing |
K_act | nothing |
r1 | nothing |
rc1 | nothing |
F | nothing |
n | nothing |
pH_m | nothing |
f | nothing |
T | nothing |
tau_Ca_f | nothing |
k_plus_3 | nothing |
delta_psi_offset | nothing |
L | nothing |
pb | nothing |
delta_J_gly_total | nothing |
beta2 | nothing |
tau_I | nothing |
Jmax_uni | nothing |
g_Ca | nothing |
J_red_basal | nothing |
K_Ca2 | nothing |
pH_i | nothing |
pa | nothing |
g | nothing |
beta4 | nothing |
Cmito | nothing |
beta_max | nothing |
u2 | nothing |
k_minus_3 | nothing |
rc2 | nothing |
p2 | nothing |
g_NS | nothing |
fm | nothing |
K_NS | nothing |
Ca_o | nothing |
TJ | nothing |
ra | nothing |
delta_J_hyd_max | nothing |
rho_res | nothing |
u1 | nothing |
K_Na | nothing |
Pi_m | nothing |
K_glu | nothing |
g_K_dr | nothing |
gamma1 | nothing |
K_F1 | nothing |
R | nothing |
rb | nothing |
Na_i | nothing |
States:
| Name | Description |
|---|---|
NADH_m(time) | nothing |
V(time) | nothing |
I(time) | nothing |
Ca_m(time) | nothing |
C(time) | nothing |
B(time) | nothing |
J(time) | nothing |
delta_J_hyd(time) | nothing |
delta_psi(time) | nothing |
n(time) | nothing |
ADP_i(time) | nothing |
ADP_m(time) | nothing |
Ca_i(time) | nothing |
mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_restrepo_karma_garfinkel_qu_weiss_2008 — v0.0.1Mahajan, Shiferaw, Sato, Baher, Olcese, Xie, Yang, Chen, Restrepo, Karma, Garfinkel, Qu, Weiss, 2008
Details
Parameters:
| Name | Description |
|---|---|
gca | 182.0 |
T | 308.0 |
cup | 0.5 |
ay | 0.05 |
kmem | 0.3 |
stim_offset | 0.0 |
xmcai | 0.0036 |
s6 | 8.0 |
sx | 3.0 |
av | 11.3 |
wca | 8.0 |
tca | 78.0329 |
xmcao | 1.3 |
taur | 30.0 |
k2t | 0.00224 |
vx | -40.0 |
xmnao | 87.5 |
vy | -40.0 |
gtos | 0.04 |
prNaK | 0.01833 |
gNaK | 1.5 |
bcal | 24.0 |
xkon | 0.0327 |
xkdna | 0.3 |
r2 | 3.0 |
xkmko | 1.5 |
xkmnai | 12.0 |
vyr | -40.0 |
ksar | 13.0 |
gkr | 0.0125 |
syr | 11.32 |
gtof | 0.11 |
Na_o | 136.0 |
gleak | 2.069e-5 |
vth | 0.0 |
gks | 0.1386 |
K_i | 140.0 |
stim_duration | 3.0 |
taups | 0.5 |
Ca_o | 1.8 |
gdyad | 9000.0 |
taupo | 1.0 |
gryr | 2.58079 |
stim_period | 400.0 |
k1t | 0.00413 |
xkcal | 7.0 |
ax | 0.3576 |
s1t | 0.00195 |
K_o | 5.4 |
taud | 4.0 |
srmax | 47.0 |
xmnai | 12.3 |
cstar | 90.0 |
gna | 12.0 |
gbarsr | 26841.8 |
gkix | 0.3 |
taua | 100.0 |
cpt | 6.09365 |
srkd | 0.6 |
gNaCa | 0.84 |
sy | 4.0 |
kj | 50.0 |
tau3 | 3.0 |
pca | 0.00054 |
stim_amplitude | -15.0 |
r1 | 0.3 |
cat | 3.0 |
bsar | 42.0 |
btrop | 70.0 |
vup | 0.4 |
bmem | 15.0 |
R | 8.314472 |
xkoff | 0.0196 |
F | 96.4853415 |
k2 | 0.000103615 |
States:
| Name | Description |
|---|---|
trops(time) | 19.864701949854 |
xi2ca(time) | 0.004173008466 |
xi1ba(time) | 3.3616596e-5 |
xr(time) | 0.007074239331 |
Ca_NSR(time) | 104.450004990523 |
xtof(time) | 0.003643592594 |
xir(time) | 0.006679257264 |
c2(time) | 0.979322592773 |
xh(time) | 0.990691306716 |
xs1(time) | 0.048267587131 |
Ca_dyad(time) | 1.716573130685 |
xs2(time) | 0.105468807033 |
Na_i(time) | 11.441712311614 |
V(time) | -87.169816169406 |
Ca_submem(time) | 0.226941113355 |
xj(time) | 0.993888937283 |
c1(time) | 1.8211252e-5 |
ytos(time) | 0.174403618112 |
xtos(time) | 0.00364776906 |
Ca_JSR(time) | 97.505463697266 |
xm(time) | 0.001075453357 |
ytof(time) | 0.993331326442 |
xi1ca(time) | 0.001208153482 |
xi2ba(time) | 0.015242594688 |
tropi(time) | 22.171689894953 |
Ca_i(time) | 0.256752008084 |
maldonado_borchers_findeisen_allgower_2006 — v0.0.1Maldonado, Borchers, Findeisen and Allgower, 2006
Details
Parameters:
| Name | Description |
|---|---|
Io | 0.0 |
SP | 250.0 |
X_c | 0.0009127 |
k_yd | 1.0 |
K_l_p | 3.0e6 |
D_A | 0.7 |
k_nokl | 100.0 |
k_nod | 1000.0 |
k_res | 0.01 |
k_y | 1.0 |
Il | 0.0 |
IP | 0.0 |
X_bss | 0.0007282 |
k_B | 0.189 |
k_for | 0.001 |
C_s | 0.005 |
k3 | 0.00058 |
k_pger | 0.0001 |
K | 10.0 |
k_Fs | 1.0 |
K_o_p | 200000.0 |
f0 | 0.05 |
ko | 0.35 |
X_y | 0.0073 |
X_yss | 0.0073 |
k_rB | 1.0 |
X_b | 0.0007282 |
k_nopg | 10.0 |
dB | 0.7 |
k4 | 0.017 |
k_byp | 0.1 |
k6 | 3.0 |
k_opgd | 0.35 |
k_yno | 20000.0 |
D_C | 0.189 |
D_R | 0.0007 |
k1 | 0.01 |
k_nopge | 1.0 |
k_pged | 100.0 |
kP | 86.0 |
X_noe | 0.0 |
k_ypge | 100.0 |
X_pgex | 0.0 |
k5 | 0.02 |
rl | 1000.0 |
k2 | 10.0 |
States:
| Name | Description |
|---|---|
x_no(time) | 0.02 |
xy(time) | 0.0073 |
xc(time) | 0.0009127 |
xr(time) | 0.0007734 |
r_B(time) | 0.9912 |
x_kl(time) | 0.01 |
x_pge(time) | 0.01 |
x_opg(time) | 0.01 |
xb(time) | 0.0007282 |
maleckar_greenstein_trayanova_giles_2009 — v0.0.1Maleckar, Greenstein, Trayanova, Giles, 2009
Details
Parameters:
| Name | Description |
|---|---|
gamma_Na | 0.45 |
k_Ca | 0.025 |
T | 306.15 |
P_Na | 0.0018 |
tau_K | 10.0 |
Mg_i | 2.5 |
stim_offset | 0.0 |
d_NaCa | 0.0003 |
tau_di | 0.01 |
alpha_rel | 200000.0 |
i_NaK_max | 68.55 |
I_up_max | 2800.0 |
phi_Na_en | 0.0 |
k_CaP | 0.0002 |
Cm | 50.0 |
Ca_b | 1.8 |
Vol_rel | 4.41e-5 |
Vol_i | 0.005884 |
g_kur | 2.25 |
Na_b | 130.0 |
Vol_up | 0.0003969 |
g_Ks | 1.0 |
g_K1 | 3.1 |
k_xcs | 0.4 |
tau_tr | 0.01 |
g_Kr | 0.5 |
k_rel_i | 0.0003 |
g_Ca_L | 6.75 |
ACh | 1.0e-24 |
pow_K_NaK_Na_15 | 36.4829 |
stim_duration | 0.006 |
g_B_Na | 0.060599 |
k_rel_d | 0.003 |
stim_period | 1.0 |
K_NaK_K | 1.0 |
k_srca | 0.5 |
g_t | 8.25 |
tau_Ca | 24.7 |
Vol_d | 0.00011768 |
r_recov | 0.815 |
i_CaP_max | 4.0 |
Vol_c | 0.000800224 |
g_B_Ca | 0.078681 |
stim_amplitude | -15.0 |
tau_Na | 14.3 |
k_cyca | 0.0003 |
E_Ca_app | 60.0 |
K_NaCa | 0.0374842 |
R | 8314.0 |
F | 96487.0 |
K_b | 5.4 |
States:
| Name | Description |
|---|---|
O_TC(time) | 0.012922 |
O_Calse(time) | 0.431547 |
O(time) | 1.38222 |
n(time) | 0.004374 |
d_L(time) | 1.4e-5 |
m(time) | 0.003289 |
f_L1(time) | 0.998597 |
s(time) | 0.948597 |
Na_i(time) | 8.516766 |
O_C(time) | 0.026766 |
pa(time) | 5.3e-5 |
Ca_rel(time) | 0.632613 |
h2(time) | 0.873881 |
O_TMgMg(time) | 0.714463 |
V(time) | -74.031982 |
K_c(time) | 5.560224 |
f_L2(time) | 0.998586 |
Ca_c(time) | 1.815768 |
K_i(time) | 129.485991 |
Ca_d(time) | 7.1e-5 |
r(time) | 0.001089 |
F1(time) | 0.470055 |
h1(time) | 0.877202 |
Na_c(time) | 130.022096 |
Ca_up(time) | 0.649195 |
a_ur(time) | 0.000367 |
Ca_i(time) | 6.5e-5 |
F2(time) | 0.002814 |
O_TMgC(time) | 0.190369 |
i_ur(time) | 0.96729 |
maltsev_2009 — v0.0.1Maltsev 2009
Details
Parameters:
| Name | Description |
|---|---|
K3ni | 26.44 |
T | 310.15 |
Km_fCa | 0.00035 |
TC_tot | 0.031 |
Km_Kp | 1.4 |
kf_TC | 88.8 |
Km_Nap | 14.0 |
K1ni | 395.3 |
EC50_SR | 0.45 |
i_NaK_max | 2.88 |
Ko | 5.4 |
MaxSR | 15.0 |
Kcni | 26.44 |
Cm | 32.0 |
L_sub | 0.02 |
g_to | 0.252 |
alpha_fCa | 0.021 |
kb_TC | 0.446 |
Qco | 0.0 |
V_nsr_part | 0.0116 |
kf_TMM | 2.277 |
Kco | 3.663 |
g_Ks | 0.0259 |
kf_CM | 227.7 |
TMC_tot | 0.062 |
kim | 0.005 |
V_i_part | 0.46 |
g_Kr | 0.08113973 |
kf_CQ | 0.534 |
tau_tr | 40.0 |
g_sus | 0.02 |
g_b_Ca | 0.0006 |
CQ_tot | 10.0 |
K1no | 1628.0 |
K_up | 0.0006 |
kb_CM | 0.542 |
Cao | 2.0 |
g_if | 0.15 |
Mgi | 2.5 |
VIf_half | -64.0 |
K2no | 561.4 |
Ki | 140.0 |
Qn | 0.4315 |
g_st | 0.003 |
tau_dif_Ca | 0.04 |
kb_TMM | 0.751 |
koCa | 10.0 |
K3no | 4.663 |
kom | 0.06 |
g_b_Na | 0.00486 |
K2ni | 2.289 |
kf_TMC | 227.7 |
MinSR | 1.0 |
ks | 250000.0 |
E_CaL | 45.0 |
kb_CQ | 0.445 |
P_up | 0.012 |
Qci | 0.1369 |
Nao | 140.0 |
HSR | 2.5 |
kiCa | 0.5 |
E_st | 37.4 |
Kci | 0.0207 |
kb_TMC | 0.00751 |
Nai | 10.0 |
V_jsr_part | 0.0012 |
kNaCa | 187.5 |
L_cell | 70.0 |
g_CaT | 0.1832 |
R_cell | 4.0 |
g_CaL | 0.464 |
CM_tot | 0.045 |
R | 8314.4 |
F | 96485.0 |
E_CaT | 45.0 |
States:
| Name | Description |
|---|---|
qa(time) | 0.42380243163 |
paS(time) | 0.453100576739 |
paF(time) | 0.144755091176 |
dT(time) | 0.00504393374639 |
I(time) | 7.86181717518e-8 |
pi_(time) | 0.849409822329 |
y(time) | 0.113643187247 |
fT(time) | 0.420757825415 |
fCQ(time) | 0.273207128393 |
O(time) | 1.7340201253e-7 |
Ca_nsr(time) | 1.49348117734 |
fTC(time) | 0.0291316176172 |
n(time) | 0.0264600410928 |
fCMs(time) | 0.054381370046 |
Ca_sub(time) | 0.000138112560112 |
fTMC(time) | 0.432694959597 |
q(time) | 0.694241313965 |
Ca_jsr(time) | 0.316762674605 |
RI(time) | 0.311951987007 |
fTMM(time) | 0.501049376634 |
fCa(time) | 0.711395919653 |
fCMi(time) | 0.0594880901438 |
r(time) | 0.00558131733359 |
qi(time) | 0.447294008304 |
Vm(time) | -57.9639346865 |
R(time) | 0.688047760973 |
dL(time) | 0.000584545564405 |
Cai(time) | 0.000150018670943 |
fL(time) | 0.862381249774 |
maly_wiley_lauffenburger_2004 — v0.0.1Maly, Wiley, Lauffenburger, 2004
Details
margaridamartins_mendes_coreiro_pocesfreire_2001 — v0.0.1Margaridamartins, Mendes, Coreiro, Pocesfreire, 2001
Details
Parameters:
| Name | Description |
|---|---|
HTA | 1.0 |
Kmq | 0.49 |
V | 0.0812 |
Kmp | 0.61 |
Kms | 0.61 |
Keq | 0.61 |
D_lactate | 0.0 |
States:
| Name | Description |
|---|---|
SDLGSH(time) | 1.0 |
GSH(time) | 1.0 |
marhl_haberichter_brumen_heinrich_2000 — v0.0.1Marhl, Haberichter, Brumen, Heinrich, 2000
Details
Parameters:
| Name | Description |
|---|---|
k_m | 0.00625 |
beta_ER | 0.0025 |
k_plus | 0.1 |
K1 | 5.0 |
K2 | 0.8 |
k_ch | 4100.0 |
k_leak | 0.05 |
Ca_tot | 90.0 |
rho_m | 0.01 |
k_in | 300.0 |
k_minus | 0.01 |
k_out | 125.0 |
Pr_tot | 120.0 |
beta_m | 0.0025 |
rho_ER | 0.01 |
K3 | 5.0 |
k_pump | 20.0 |
States:
| Name | Description |
|---|---|
Ca_cyt(time) | 0.05 |
Ca_m(time) | 0.4 |
Ca_ER(time) | 1.0 |
marhl_schuster_brumen_heinrich_1997 — v0.0.1Marhl, Schuster, Brumen, Heinrich, 1997
Details
Parameters:
| Name | Description |
|---|---|
k_pump | 76.0 |
T | 310.0 |
k_leak | 10.0 |
A_tot | 3890.0 |
Ca_tot | 45.0 |
C_tot | 5000.0 |
Vcyt | 5.84e-11 |
k_minus | 0.5 |
rho | 0.01 |
S | 0.00616 |
Pr_tot | 600.0 |
g_Ca_max | 100.0 |
K_Ca | 5.0 |
R | 8.3143 |
F | 96.4867 |
k_plus | 0.1 |
States:
| Name | Description |
|---|---|
Pr(time) | nothing |
Ca_cyt(time) | nothing |
martinov_vitvitsky_mosharov_banerjee_ataullakhanov_2000 — v0.0.1Martinov, Vitvitsky, Mosharov, Banerjee, Ataullakhanov, 2000
Details
Parameters:
| Name | Description |
|---|---|
V_MATIIImax | 22870.0 |
Km2_MATIII | 21.1 |
Ki_GNMT | 20.0 |
V_MATImax | 561.0 |
V_METmax | 4544.0 |
Km_GNMT | 4500.0 |
V_GNMTmax | 10600.0 |
Km_MATI | 41.0 |
alpha_d | 1333.0 |
K_AHC | 0.1 |
Ki_MATI | 50.0 |
Km2_MET_A | 10.0 |
Ado | 1.0 |
States:
| Name | Description |
|---|---|
AdoHcy(time) | 3.0 |
AdoMet(time) | 60.0 |
marwan_2003 — v0.0.1Marwan, 2003
Details
Parameters:
| Name | Description |
|---|---|
glucose | 1.0 |
alpha2 | 50.0 |
alpha1 | 30.0 |
kia | 0.1 |
kai | 0.8 |
kd | 0.1 |
Ifr_sigma_fr_phi_fr | 0.1 |
kx | 0.2 |
kG | 0.1 |
ky | 1.0 |
Ir_sigma_r_phi_r | 0.0 |
States:
| Name | Description |
|---|---|
Pr(time) | 0.0 |
prepreS(time) | 200.0 |
Pfr(time) | 10.0 |
Ya(time) | 0.9 |
V(time) | 50.0 |
Xa(time) | 0.0 |
S(time) | 0.0 |
Xi(time) | 6.0 |
preS(time) | 0.0 |
matsuoka_sarai_kuratomi_ono_noma_2003 — v0.0.1Matsuoka, Sarai, Kuratomi, Ono, Noma, 2003
Details
Parameters:
| Name | Description |
|---|---|
Y_d | 0.027 |
k_C_U | 0.143 |
P_lCa | 0.11 |
stim_start | 50.0 |
T | 310.0 |
P_Na | 2860.0 |
P_Ks_Na | 0.2016 |
P_NaCa | 6.81 |
KForceEC | 140000.0 |
L | 0.9623799975411884 |
V_rel | 160.0 |
Km_CaSR | 0.08 |
Km_Ki | 32.88 |
Km_Nai | 8.75 |
B | 1.2 |
k_C_CCa | 6.954 |
P_Ks_K | 5.04 |
k_CCa_UCa | 0.0003 |
Ko | 5.4 |
P_Cab | 0.04 |
CMDN_max | 0.05 |
P_KATP | 0.0236 |
Cm | 132.0 |
Z_2 | 0.0039 |
P_SR_T | 386.0 |
k_AI_AP | 8.75e-5 |
P_bNSC | 0.385 |
P_NaK | 21.0 |
h_c | 0.005 |
beta_y2 | 0.004444 |
Y_4 | 0.12 |
Y_1 | 39.0 |
k3 | 1.0 |
k_UCa_CCa | 0.35 |
Z_1 | 0.03 |
ZeroForceEL | 0.97 |
Adenosine_Total | 5.0 |
ProducingRate_Max | 0.003 |
P_Kr | 0.00864 |
Z_3 | 1560.0 |
ForceFactor | 1.8e6 |
P_RyR | 62000.0 |
k_CCa_C | 0.0042 |
Km_ATP | 0.1 |
KForceLinearEc | 200.0 |
P_CaL | 8712.0 |
stim_duration | 2.0 |
P_SR_L | 459.0 |
Y_3 | 0.03 |
Cao | 1.8 |
P_to_K | 0.033 |
k_U_UCa | 6.954 |
Km_Cai | 0.00138 |
Km_Ko | 0.258 |
stim_period | 400.0 |
stim_end | 1.0e6 |
Km_Nao | 87.5 |
Km_CaCyto | 0.0008 |
k4 | 0.000849 |
N | 2333.0 |
K_mCMDN | 0.00238 |
K_mCSQN | 0.8 |
L_a | 1.17 |
Y_2 | 0.0039 |
Vi | 8000.0 |
k_AP_AI | 0.004 |
P_to_Na | 0.00297 |
k_U_C | 0.35 |
Nao | 140.0 |
Km_Cao | 1.38 |
Diadid_Factor | -150.0 |
Partition | 0.32 |
V_up | 400.0 |
P_K1_0 | 1.146 |
k1 | 0.01 |
i_max | 162500.0 |
stim_amplitude | -4000.0 |
CSQN_max | 10.0 |
P_CaT | 612.0 |
T_t | 0.07 |
R | 8.3143 |
k2 | 0.04 |
F | 96.4867 |
States:
| Name | Description |
|---|---|
y2(time) | 0.20443083454225305 |
Caup(time) | 2.611712901567567 |
p_U(time) | 0.17246483915629204 |
X(time) | 0.9573749975411884 |
p_AP_CaL(time) | 1.5445004166497696e-6 |
p_open_RyR(time) | 0.00034314360001543243 |
p_close_RyR(time) | 0.19135178123107768 |
y1(time) | 1.6882718240109127e-5 |
y(time) | 0.6080573900752752 |
Ca_Total(time) | 9.455741736977666 |
pCaCB(time) | 0.001990153835322864 |
p_AI_Na(time) | 0.40285968661346977 |
ATPi(time) | 4.657102729020499 |
y3(time) | 0.967887666264921 |
p_RP_CaL(time) | 0.9968480629364956 |
Nai(time) | 4.925761439682025 |
p_AP_Na(time) | 1.779648367445368e-5 |
p_UCa(time) | 6.098246017787626e-5 |
pCB(time) | 0.00042941813853474524 |
p_RP_Na(time) | 0.3556412697995689 |
Ki(time) | 143.1837333000449 |
p_C(time) | 0.4250747299372254 |
Vm(time) | -85.95752434460744 |
p_AI_CaL(time) | 0.000877325391245903 |
pCa(time) | 0.02490898775497523 |
maurya_bornheimer_venkatasubramanian_subramaniam_2005 — v0.0.1Maurya et al. 2005
Details
Parameters:
| Name | Description |
|---|---|
G_tot | 1.0e-8 |
P_minus2 | 25.0 |
P_minus4 | 25.0 |
k1 | 529000.0 |
P_minus3 | 0.013 |
k2 | 1.28 |
P_minus1 | 0.013 |
States:
| Name | Description |
|---|---|
Pi_(time) | 0.0044 |
RG(time) | 0.0 |
T(time) | 0.000468 |
RGD(time) | 0.0 |
GD(time) | 1.0e-8 |
GAD(time) | 0.0 |
GT(time) | 0.0 |
RGT(time) | 0.0 |
A(time) | 0.0 |
G(time) | 0.0 |
R(time) | 0.0 |
GA(time) | 0.0 |
RGAT(time) | 0.0 |
RGA(time) | 0.0 |
D(time) | 0.000149 |
GAT(time) | 0.0 |
RGAD(time) | 0.0 |
mazhari_greenstein_winslow_marban_nuss_2001 — v0.0.1Mazhari, Greenstein, Winslow, Marban, Nuss, 2001
Details
Parameters:
| Name | Description |
|---|---|
Kb | 0.1348 |
Kf | 0.0266 |
Vm | -80.0 |
States:
| Name | Description |
|---|---|
O(time) | nothing |
I(time) | nothing |
C2(time) | nothing |
C1(time) | nothing |
C3(time) | nothing |
mcallister_noble_tsien_1975 — v0.0.1Mcallister, Noble, Tsien, 1975
Details
Parameters:
| Name | Description |
|---|---|
g_Clb | 0.01 |
g_si | 0.8 |
C | 10.0 |
E_Cl | -70.0 |
g_Na | 150.0 |
g_Nab | 0.105 |
E_K | -110.0 |
g_qr | 2.5 |
E_si | 70.0 |
E_Na | 40.0 |
E_K1 | -30.0 |
g_si_ | 0.04 |
E_s | -52.0 |
States:
| Name | Description |
|---|---|
d(time) | 0.00293135 |
r(time) | 0.13500116 |
V(time) | -78.041367 |
h(time) | 0.78656359 |
m(time) | 0.02566853 |
x2(time) | 0.0176854 |
s(time) | 0.75473994 |
f(time) | 0.80873917 |
x1(time) | 0.02030289 |
q(time) | 3.11285794 |
mckenzie_sneyd_1998 — v0.0.1Mckenzie, Sneyd, 1998
Details
mclean_su_vandenbogert_2003 — v0.0.1Mclean, Su, Vandenbogert, 2003
Details
Parameters:
| Name | Description |
|---|---|
g_max | 1.5 |
L_CE_opt | 0.01 |
W | 0.63 |
A | 0.25 |
L_slack | 0.0025 |
k_SEE | 1.0e6 |
a | 0.8 |
S | 2.0 |
F_max | 7000.0 |
F_min | 10.0 |
V_max | 0.93 |
gamma | 5.67 |
States:
| Name | Description |
|---|---|
g_V_CE(time) | nothing |
L_CE(time) | nothing |
mears_sheppard_atwater_rojas_bertram_sherman_1997 — v0.0.1Mears 1997
Details
Parameters:
| Name | Description |
|---|---|
V_CRAC | 0.0 |
sloper | 3.0 |
f | 0.01 |
kerp | 0.09 |
dip3 | 0.2 |
sigma_er | 1.0 |
g_K_Ca | 1200.0 |
Vm_f | -20.0 |
Vj | -53.0 |
V_K | -70.0 |
Sj | 2.0 |
IP3 | 0.0 |
g_Ca_f | 810.0 |
Vn | -15.0 |
verp | 0.24 |
Sm_s | 10.0 |
lambda_n | 1.85 |
lambda_er | 250.0 |
Cm | 6158.0 |
dinh | 0.4 |
kmp | 0.35 |
Vm_s | -16.0 |
Sm_f | 7.5 |
Ca_er_bar | 40.0 |
Sn | 6.0 |
g_K | 3900.0 |
g_K_ATP | 150.0 |
dact | 0.35 |
perl | 0.003 |
V_Ca | 100.0 |
g_leak | 0.0 |
gamma | 3.607e-6 |
g_Ca_s | 510.0 |
vmp | 0.08 |
g_CRAC | 75.0 |
kdkca | 0.55 |
States:
| Name | Description |
|---|---|
jm(time) | 0.12 |
V(time) | -61.0 |
n(time) | 0.0005 |
Ca_i(time) | 0.11 |
Ca_er(time) | 60.0 |
Medrano_Gracia_PCA_2013 — v0.0.1Large Scale Left Ventricular Shape Atlas Using Automated Model Fitting to Contours
Details
The model gives a statistical model of left ventricular cardiac shape (built using Principal Components Analysis). In this repository, the data has been converted into JSON format, and can be loaded into a WebGL based model visualiser.
MetabolicComponentLibrary — v0.0.1Metabolic Component Library
Details
Library of CellML metabolic components.
michailova_mcculloch_2001 — v0.0.1Michailova, Mcculloch, 2001
Details
Parameters:
| Name | Description |
|---|---|
k_a_minus | 576.0 |
K_mEGTA | 0.00015 |
stim_start | 0.1 |
k_minus_CaADP | 193500.0 |
Vmaxr | 0.318 |
tau_xfer_MgADP | 0.0534 |
k_minus_MgATP | 10875.0 |
omega | 10.0 |
k_b_minus | 1930.0 |
k_plus_CaATP | 225000.0 |
V_NSR | 2.1e-6 |
ADP_tot | 0.005 |
K_mNa | 87.5 |
eta | 0.35 |
k_minus_MgADP | 84500.0 |
LTRPN_tot | 0.07 |
g_Ks | 0.0027134 |
tau_tr | 0.0005747 |
g_Kr | 0.0034 |
K_mCa | 1.38 |
k_a_plus | 1.215e13 |
V_ss | 1.2e-9 |
Na_o | 138.0 |
fprime | 7.0 |
v1 | 1800.0 |
b | 2.0 |
g_Nab | 0.0031 |
tau_xfer | 0.0267 |
tau_xfer_MgATP | 0.0534 |
MgATP_i0 | 2.888 |
tau_xfer_CaATP | 0.0534 |
gprime | 7000.0 |
k_ltrpn_minus | 40.0 |
I_pCa | 0.05 |
I_NaK | 0.693 |
k_plus_MgATP | 125000.0 |
CSQN_tot | 15.0 |
N_rb | 1.0 |
g_Kp | 0.002216 |
stim_amplitude | -100.0 |
m | 3.0 |
F | 96.4853415 |
n | 4.0 |
f | 300.0 |
K_mNa_i | 10.0 |
T | 310.0 |
C_sc | 0.001 |
K_SR | 1.0 |
i_Ca_half | -0.265 |
k_htrpn_plus | 20000.0 |
K_sat | 0.2 |
K_mK1 | 13.0 |
tau_xfer_CaADP | 0.0534 |
tau_xfer_Mg | 0.0267 |
ATP_tot | 7.0 |
k_htrpn_minus | 0.066 |
g | 2000.0 |
k_b_plus | 4.05e9 |
k_c_plus | 100.0 |
g_K1 | 2.8 |
V_myo | 2.584e-5 |
k_c_minus | 0.8 |
k_plus_MgADP | 125000.0 |
EGTA_tot | 0.0 |
stim_duration | 0.0005 |
K_mK_o | 1.5 |
Ca_o | 2.0 |
K_mpCa | 5.0e-5 |
a | 2.0 |
tau_factor | 1.0 |
stim_period | 1.0 |
stim_end | 1.0e8 |
V_JSR | 1.6e-7 |
K_mCSQN | 0.8 |
K_mCMDN | 0.00238 |
K_o | 4.0 |
K_fb | 0.000168 |
k_minus_CaATP | 45000.0 |
A_cap | 0.0001534 |
k_ltrpn_plus | 40000.0 |
CMDN_tot | 0.05 |
N_fb | 1.2 |
HTRPN_tot | 0.14 |
g_to1 | 0.23815 |
P_Ca | 0.0003125 |
g_Na | 12.8 |
Vmaxf | 0.0813 |
g_Cab | 0.0003842 |
k_plus_CaADP | 125000.0 |
K_rb | 3.29 |
K_NaCa | 0.3 |
R | 8.314472 |
P_K | 5.79e-7 |
States:
| Name | Description |
|---|---|
Ca_NSR(time) | 0.262 |
MgADP_i(time) | 0.00298 |
C0(time) | 0.997208 |
y(time) | 0.798 |
C3(time) | 1.63909e-14 |
HTRPNCa(time) | 0.98 |
O(time) | 9.84546e-21 |
C_Ca0(time) | 0.00272826 |
CaADP_i(time) | 1.1e-7 |
Mg_ss(time) | 1.0 |
C_Ca3(time) | 2.87031e-15 |
X_to1(time) | 2.63 |
LTRPNCa(time) | 0.078 |
X_ks(time) | 0.264 |
V(time) | -96.1638 |
C_Ca1(time) | 6.99215e-7 |
C1(time) | 6.38897e-5 |
O_Ca(time) | 0.0 |
P_O2(time) | 0.0 |
C_Ca2(time) | 6.71989e-11 |
X_kr(time) | 0.51 |
P_C1(time) | 0.47 |
Ca_ss(time) | 0.0001315 |
P_C2(time) | 0.53 |
C2(time) | 1.535e-9 |
CaATP_i(time) | 0.000237 |
MgATP_ss(time) | 6.4395 |
j(time) | 0.99254 |
CaATP_ss(time) | 0.00025 |
m(time) | 0.0328302 |
C4(time) | 6.56337e-20 |
Y_to1(time) | 0.99 |
Na_i(time) | 10.0 |
CaADP_ss(time) | 1.3e-7 |
Mg_i(time) | 1.0 |
MgATP_i(time) | 6.4395 |
C_Ca4(time) | 4.59752e-20 |
h(time) | 0.988354 |
K_i(time) | 159.48 |
P_O1(time) | 0.0 |
Ca_JSR(time) | 0.2616 |
MgADP_ss(time) | 0.00298 |
Ca_i(time) | 8.464e-5 |
michailova_saucerman_belik_mcculloch_2005 — v0.0.1Michailova 2005
Details
Parameters:
| Name | Description |
|---|---|
k_a_minus | 576.0 |
K_mEGTA | 0.00015 |
stim_start | 0.1 |
k_minus_CaADP | 193500.0 |
Vmaxr | 0.318 |
tau_xfer_MgADP | 0.0534 |
k_minus_MgATP | 10875.0 |
omega | 10.0 |
k_b_minus | 1930.0 |
k_plus_CaATP | 225000.0 |
V_NSR | 2.1e-6 |
ADP_tot | 0.005 |
gd | 0.89 |
K_mNa | 87.5 |
eta | 0.35 |
k_minus_MgADP | 84500.0 |
LTRPN_tot | 0.07 |
g_Ks | 0.0027134 |
tau_tr | 0.0005747 |
g_Kr | 0.0034 |
K_mCa | 1.38 |
k_a_plus | 1.215e13 |
V_ss | 1.2e-9 |
Na_o | 138.0 |
v1 | 1800.0 |
b | 2.0 |
g_Nab | 0.0031 |
tau_xfer | 0.0267 |
tau_xfer_MgATP | 0.0534 |
MgATP_i0 | 2.888 |
tau_xfer_CaATP | 0.0534 |
k_ltrpn_minus | 40.0 |
I_pCa | 0.05 |
I_NaK | 0.693 |
k_plus_MgATP | 125000.0 |
k_MgATP_ss | 1.4 |
CSQN_tot | 15.0 |
N_rb | 1.0 |
g_Kp | 0.002216 |
stim_amplitude | -100.0 |
m | 3.0 |
K_o_normal | 4.5 |
F | 96.4853415 |
n | 4.0 |
f | 300.0 |
K_mNa_i | 10.0 |
T | 310.0 |
k_MgADP | 0.4 |
C_sc | 0.001 |
K_SR | 1.0 |
k_htrpn_plus | 20000.0 |
G_K_ATP | 0.05 |
K_sat | 0.2 |
K_mK1 | 13.0 |
p_prime_k | 6.658e-7 |
tau_xfer_CaADP | 0.0534 |
tau_xfer_Mg | 0.0267 |
ATP_tot | 7.0 |
k_htrpn_minus | 0.066 |
g | 2000.0 |
k_b_plus | 4.05e9 |
k_c_plus | 100.0 |
g_K1 | 2.8 |
V_myo | 2.584e-5 |
k_c_minus | 0.8 |
k_plus_MgADP | 125000.0 |
EGTA_tot | 0.0 |
stim_duration | 0.0005 |
K_mK_o | 1.5 |
Ca_o | 2.0 |
K_mpCa | 5.0e-5 |
a | 2.0 |
tau_factor | 1.0 |
stim_period | 1.0 |
stim_end | 1.0e8 |
V_JSR | 1.6e-7 |
K_mCSQN | 0.8 |
K_mCMDN | 0.00238 |
K_o | 4.0 |
K_fb | 0.000168 |
k_minus_CaATP | 45000.0 |
go | 0.08 |
k_ltrpn_plus | 40000.0 |
A_cap | 0.0001534 |
CMDN_tot | 0.05 |
N_fb | 1.2 |
HTRPN_tot | 0.14 |
g_to1 | 0.23815 |
P_Ca | 0.0003594 |
g_Na | 12.8 |
k_ATP | 0.6 |
Vmaxf | 0.0813 |
g_Cab | 0.0003842 |
k_plus_CaADP | 125000.0 |
K_rb | 3.29 |
K_NaCa | 0.3 |
R | 8.314472 |
States:
| Name | Description |
|---|---|
X_kr(time) | 0.51 |
P_C1(time) | 0.47 |
Ca_ss(time) | 0.0001315 |
MgADP_i(time) | 0.00298 |
P_C2(time) | 0.53 |
v(time) | 0.1 |
y(time) | 0.798 |
Ca_NSR(time) | 0.262 |
HTRPNCa(time) | 0.98 |
CaATP_i(time) | 0.000237 |
MgATP_ss(time) | 6.4395 |
CaADP_i(time) | 1.1e-7 |
Mg_ss(time) | 1.0 |
CaATP_ss(time) | 0.00025 |
j(time) | 0.99254 |
X_to1(time) | 2.63 |
m(time) | 0.0328302 |
Y_to1(time) | 0.99 |
w(time) | 0.1 |
CaADP_ss(time) | 1.3e-7 |
Mg_i(time) | 1.0 |
MgATP_i(time) | 6.4395 |
Na_i(time) | 10.0 |
LTRPNCa(time) | 0.078 |
X_ks(time) | 0.264 |
V(time) | -96.1638 |
h(time) | 0.988354 |
z(time) | 0.1 |
K_i(time) | 159.48 |
P_O1(time) | 0.0 |
Ca_JSR(time) | 0.2616 |
MgADP_ss(time) | 0.00298 |
P_O2(time) | 0.0 |
Ca_i(time) | 8.464e-5 |
miftakhov_abdusheva_christensen_1999 — v0.0.1Miftakhov, Abdusheva, Christensen, 1999
Details
Parameters:
| Name | Description |
|---|---|
E_Ca | 80.0 |
K_c | 0.00425 |
E_Cl | -40.0 |
alpha | 0.12 |
tau_x_Ca | 500.0 |
g_Cl | 0.003 |
rho | 125.0 |
g_K | 0.3 |
E_K | -75.0 |
g_Ca_K | 0.03 |
g_Ca_L | 0.004 |
g_Ca_T | 0.51 |
lamda | 12.5 |
Cm | 2.5 |
States:
| Name | Description |
|---|---|
V(time) | -55.0 |
n(time) | 0.01 |
h(time) | 0.01 |
x_Ca(time) | 0.01 |
Ca(time) | 0.0001 |
mijailovich_butler_fredburg_2000 — v0.0.1Mijailovich, Butler, Fredburg, 2000
Details
Parameters:
| Name | Description |
|---|---|
fp | 0.44 |
gp | 0.11 |
gp1 | 0.22 |
fp1 | 0.88 |
gx | 0.11 |
k5 | 0.1 |
k2 | 0.1 |
g1 | 0.01 |
States:
| Name | Description |
|---|---|
AMp(time) | 0.0 |
Mp(time) | 0.0 |
M(time) | 1.0 |
AM(time) | 0.0 |
mikane_araki_kohno_nakayama_suzuki_shimuzi_matsubara_hirakawa_takaki_suga_1997 — v0.0.1Mikane, Araki, Kohno, Nakayama, Suzuki, Shimuzi, Matsubara, Hirakawa, Takaki, Suga, 1997
Details
Parameters:
| Name | Description |
|---|---|
Ca_tot_released | 35.0 |
f | 400000.0 |
total_CB | 150.0 |
g | 10.0 |
total_Tn | 70.0 |
k_2 | 10.0 |
k_3 | 1000.0 |
k_1 | 5.0e6 |
States:
| Name | Description |
|---|---|
TnCa_t(time) | 0.0 |
cumCB_off_t(time) | 0.0 |
Ca_released(time) | 0.0 |
Ca_t(time) | 0.0 |
CB_on_t(time) | 0.0 |
Ca_sequestered(time) | 0.0 |
cumCB_on_t(time) | 0.0 |
mitchell_schaeffer_2003 — v0.0.1Mitchell, Schaeffer, 2003
Details
Parameters:
| Name | Description |
|---|---|
tau_out | 6.0 |
IstimPeriod | 500.0 |
IstimAmplitude | 0.2 |
tau_in | 0.3 |
IstimPulseDuration | 1.0 |
tau_open | 120.0 |
tau_close | 150.0 |
V_gate | 0.13 |
IstimStart | 0.0 |
IstimEnd | 50000.0 |
States:
| Name | Description |
|---|---|
Vm(time) | 8.20413566106744e-6 |
h(time) | 0.8789655121804799 |
mittler_sulzer_neumann_perelson_1998 — v0.0.1Mittler, Sulzer, Neumann, Perelson, 1998
Details
Parameters:
| Name | Description |
|---|---|
p | 774.0 |
tau_p | 0.0 |
c | 3.0 |
VI_0 | 200000.0 |
m | 0.01 |
k | 2.4e-5 |
b | 0.25 |
delta | 0.5 |
n | 4.0 |
States:
| Name | Description |
|---|---|
VNI(time) | 0.0 |
VI(time) | 200000.0 |
E2(time) | 0.0 |
I(time) | 0.1 |
E3(time) | 0.0 |
E4(time) | 0.0 |
E1(time) | 0.0 |
mlcek_neumann_kittnar_novak_2001 — v0.0.1Mlcek, Neumann, Kittnar, Novak, 2001
Details
modularmassactionprimer — v0.0.1A Primer on Modular Mass Action Modelling with CellML
Details
Example code for the book chapter 'A Primer on Modular Mass Action Modelling with CellML'. Please select one of the Exposures below to access the code.
mohr_taylor_newell_2008 — v0.0.1Mohr, Taylor, Newell, 2008
Details
morris_lecar_1981 — v0.0.1Morris and Lecar 1981
Details
Parameters:
| Name | Description |
|---|---|
i_app | 300.0 |
V3 | -1.0 |
E_L | -50.0 |
E_Ca | 100.0 |
C | 20.0 |
g_L | 2.0 |
V4 | 14.5 |
lambda_n_bar | 0.066666667 |
lambda_m_bar | 1.0 |
V1 | 10.0 |
g_K | 8.0 |
E_K | -70.0 |
V2 | 15.0 |
g_Ca | 4.0 |
States:
| Name | Description |
|---|---|
V(time) | -50.0 |
n(time) | 0.001 |
m(time) | 0.1 |
mosekilde_lading_yanchuk_maistrenko_2001 — v0.0.1Mosekilde, Lading, Yanchuk, Maistrenko, 2001
Details
moss_kazmierczak_kirley_harris_2009 — v0.0.1Moss, Kazmierczak, Kirley, Harris, 2009
Details
muller_obeyesekere_mills_ram_2008 — v0.0.1Muller, Obeyesekere, Mills, Ram, 2008
Details
Parameters:
| Name | Description |
|---|---|
b1 | 10.0 |
f24 | 0.8 |
f13 | 0.6 |
f35 | 0.3 |
a1 | 10.0 |
a2 | 10.0 |
b2 | 10.0 |
d1 | 0.2 |
E | 10.0 |
f14 | 0.1 |
f53 | 1.5 |
f45 | 0.1 |
d5 | 1.0 |
h36 | 0.1 |
d3 | 1.0 |
d6 | 0.001 |
d4 | 1.1 |
d2 | 0.1 |
States:
| Name | Description |
|---|---|
y2(time) | 0.0 |
y3(time) | 0.0 |
y1(time) | 0.0 |
y4(time) | 0.0 |
y5(time) | 0.0 |
y6(time) | 0.0 |
Myocardial_contractility_and_regional_work — v0.0.1Myocardial contractility and regional work throughout the cardiac cycle using FEM and MRI
Details
N
nagano_gerritsen_2001 — v0.0.1Nagano and Gerritsen, 2001
Details
Parameters:
| Name | Description |
|---|---|
slope | 2.0 |
alpha | 1449.027 |
L_slack | 0.42 |
B_REL | 5.2 |
width | 0.888 |
A_REL | 0.41 |
F_max | 3277.4 |
Factor | 1.0 |
F_asympt | 1.5 |
L_ce_opt | 0.055 |
q | 1.0 |
States:
| Name | Description |
|---|---|
L_ce(time) | 0.05 |
nagerl_novo_mody_vergara_2000 — v0.0.1Nagerl, Novo, Mody, Vergara, 2000
Details
Parameters:
| Name | Description |
|---|---|
koff_D | nothing |
Ca_T | nothing |
kon_D | nothing |
alpha | nothing |
D_T | nothing |
kon_Bi | nothing |
kon_DM | nothing |
Bi | nothing |
koff_DM | nothing |
DM_T | nothing |
koff_Bi | nothing |
koff_DM_ | nothing |
tau_photolysis | nothing |
t_pulse | nothing |
States:
| Name | Description |
|---|---|
CaD(time) | nothing |
CaDM2(time) | nothing |
CaDM1(time) | nothing |
CaBi(time) | nothing |
nash_panfilov_2004 — v0.0.1Nash, Panfilov, 2004
Details
nazaret_heiske_thurley_mazat_2009 — v0.0.1Nazaret, Heiske, Thurley and Mazat, 2009
Details
nelson_murray_perelson_2000 — v0.0.1Nelson, Murray, Perelson, 2000
Details
Parameters:
| Name | Description |
|---|---|
delta_1 | 0.03 |
c | 3.0 |
m | 0.01 |
np | 1.0 |
N | 480.0 |
k | 3.43e-5 |
lambda | 5.0 |
tau | 1.0 |
delta | 0.5 |
States:
| Name | Description |
|---|---|
VNI(time) | 0.0 |
VI(time) | 134000.0 |
T(time) | 180.0 |
T_star(time) | 3.6 |
nelson_perelson_1995 — v0.0.1Nelson, Perelson 1995
Details
Parameters:
| Name | Description |
|---|---|
N_0 | 300.0 |
k_1 | 2.4e-5 |
s_0 | 10.0 |
T_max | 1500.0 |
k_1_ | 2.4e-7 |
r | 0.03 |
k_s | 0.48 |
mu_TD | 0.02 |
t_c | 7305.0 |
mu_V | 2.4 |
mu_b | 0.24 |
D_0 | 0.1 |
theta | 1.0 |
mu_T | 0.02 |
mu_D | 0.76 |
mu_bD | 0.12 |
k_2 | 0.017 |
gamma | 25.0 |
t_DIV | 2557.0 |
k_1D | 2.4e-5 |
States:
| Name | Description |
|---|---|
T_D2(time) | 0.0 |
T_2(time) | 0.0 |
V_(time) | 0.0 |
V(time) | 0.001 |
T(time) | 1000.0 |
T_1(time) | 0.0 |
D(time) | 0.0 |
T_D1(time) | 0.0 |
D_ode(time) | 0.0 |
neumann_lam_dahari_gretch_wiley_layden_perelson_1998 — v0.0.1Neumann, Lam, Dahari, Gretch, Wiley, Layden, Perelson, 1998
Details
Parameters:
| Name | Description |
|---|---|
delta | 0.5 |
beta | 3.0e-7 |
c | 5.0 |
epsilon | 0.99 |
eta | 0.8 |
s | 10.0 |
p | 100.0 |
d | 0.02 |
States:
| Name | Description |
|---|---|
V(time) | 9.4e6 |
I(time) | 0.0 |
T(time) | 1000.0 |
nevo_golding_neumann_schwartz_akselrod_2004 — v0.0.1Nevo, Golding, Neumann, Schwartz, Akselrod, 2004
Details
niederer_hunter_smith_2006 — v0.0.1Niederer, Hunter, Smith, 2006
Details
Parameters:
| Name | Description |
|---|---|
T_ref | 56.2 |
Ca_50ref | 0.00105 |
n_Hill | 3.0 |
z_p | 0.85 |
A_1 | -29.0 |
a | 0.35 |
K_z | 0.15 |
alpha_2 | 0.13 |
alpha_r1 | 0.002 |
A_2 | 138.0 |
beta_0 | 4.9 |
k_on | 100.0 |
k_Ref_off | 0.2 |
alpha_3 | 0.625 |
n_Rel | 3.0 |
Ca_TRPN_Max | 0.07 |
alpha_r2 | 0.00175 |
gamma_trpn | 2.0 |
alpha_1 | 0.03 |
beta_1 | -4.0 |
A_3 | 129.0 |
alpha_0 | 0.008 |
States:
| Name | Description |
|---|---|
Q_2(time) | 0.0 |
Q_3(time) | 0.0 |
TRPN(time) | 0.067593139865 |
z(time) | 0.014417937837 |
Q_1(time) | 0.0 |
niederer_smith_2007 — v0.0.1Niederer, Smith, 2007
Details
Parameters:
| Name | Description |
|---|---|
KA | 21.4935205515214 |
kp1 | 4677.0 |
Cle | 126.0 |
PP_co2e | 0.05 |
g_Cl | 2.0e-5 |
Ae | 140.0 |
B_CMDN | 0.05 |
K_CMDN | 0.00238 |
scale_K | 0.0 |
alpha_2 | 0.13 |
k_on | 100.0 |
d | 100.0 |
Na_e | 140.0 |
J_CO2 | 0.0 |
theta_R | 0.012 |
g_H | 4.0e-6 |
K_HCO3 | 0.008017 |
k_sat | 0.1 |
K_mNa | 87.5 |
eta | 0.35 |
delta_VL | 7.0 |
J_R | 2.0e-11 |
Nae | 140.0 |
K_mCa | 1.38 |
ib1 | 31.2044223705215 |
A_3 | 129.0 |
alpha_0 | 0.008 |
g_SAC | 4.1333e-7 |
kr_co2hyd | 0.481 |
a_endo | 0.583 |
Na_o | 140.0 |
Ca_50ref | 0.00105 |
pKa_ib2 | 7.48048792987277 |
n_Hill | 3.0 |
km1 | 777.92 |
b | 14.0 |
g_ss | 7.0e-6 |
K_z | 0.15 |
V_SR | 2.098e-6 |
g_pCa | 3.5e-6 |
g_D | 6.5e-11 |
b_endo | 0.417 |
alpha_r1 | 0.002 |
P_atm | 760.0 |
f_Na | 0.2 |
g_NCX | 0.0385 |
K_m_Na | 10.0 |
n_Rel | 3.0 |
g_t | 3.5e-5 |
n_Hi | 2.91 |
pH_scale | 1.0 |
gamma_trpn | 2.0 |
g_f | 1.45e-6 |
K_Cl | 983.5 |
stim_amplitude | -0.0006 |
tau_L | 650.0 |
Pco2 | 5.8e-5 |
phi_L | 2.35 |
K_RyR | 0.041 |
NO_on | 0.0 |
g_SRl | 5.2e-6 |
kf_co2hyd | 0.000365 |
kp2 | 6.656 |
F | 96487.0 |
ib2 | 6.84513535697271 |
T | 295.0 |
c | 0.01 |
K_m_K | 1.5 |
A_1 | -29.0 |
phi_R_base | 0.05 |
pKa_ib1 | 6.40013149605198 |
K_He | 6.53e-5 |
i_NaK_max | 9.5e-5 |
K_L | 0.00022 |
g_B_K | 1.38e-7 |
g_Ko | 1.2e-6 |
Q_10Scaler | 0.35 |
alpha_r2 | 0.00175 |
J_L | 9.13e-13 |
V_myo | 2.584e-5 |
g_K1 | 2.4e-5 |
KB | 1.77948608115949e-7 |
K_Hi | 0.000183 |
CO_2sol | 0.03253 |
tau_R | 2.43 |
CmF | 0.0001 |
SAC_on | 0.0 |
E_R | -10.0 |
T_ref | 56.2 |
stim_duration | 10.0 |
V_L0 | -2.0 |
z_p | 0.85 |
B_TRPN | 0.07 |
Ca_o | 2.0 |
g_B_Na | 8.015e-8 |
K_mpCa | 0.0005 |
a | 0.35 |
Ca_e | 2.0 |
delta | 0.075 |
stim_period | 1000.0 |
pH_e | 7.4 |
ExtensionRatio | 1.0 |
N | 75000.0 |
K_o | 5.4 |
TRPN_tot | 0.07 |
A_cap | 0.01534 |
beta_0 | 4.9 |
A_2 | 138.0 |
pH_on | 0.0 |
K_SERCA | 0.0005 |
alpha_3 | 0.625 |
g_SERCA | 0.00045 |
g_Na | 0.0008 |
alpha_1 | 0.03 |
K_Na | 4866.11 |
g_Cab | 2.4216e-8 |
beta_1 | -4.0 |
k_off | 0.2 |
scale_Na | 0.0 |
n_He | 2.18 |
t_L | 1.0 |
R | 8314.5 |
K_OH | 0.0008907 |
States:
| Name | Description |
|---|---|
z_1(time) | 0.988955429362334 |
y(time) | 0.00331726547133295 |
z_2(time) | 0.00860686643357905 |
s_slow(time) | 0.530207467628341 |
j(time) | 0.675294627571238 |
Q_3(time) | 0.0 |
z_3(time) | 0.00241692704700704 |
m(time) | 0.00419283833975832 |
s(time) | 0.922573773425153 |
Na_i(time) | 10.9735342589175 |
HCO3i(time) | 15.1428688811927 |
TRPN(time) | 0.0670845085340179 |
V(time) | -80.5561112771341 |
Cli(time) | 16.2285651746901 |
h(time) | 0.675647510010602 |
r_ss(time) | 0.00289374682707489 |
z(time) | 0.0175189833295748 |
K_i(time) | 142.021261491871 |
s_ss(time) | 0.308572839431787 |
Q_2(time) | 0.0 |
r(time) | 0.00218107055088884 |
CO2i(time) | 1.23610845162584 |
Ca_SR(time) | 0.843733859307907 |
Ca_i(time) | 8.60587059887361e-5 |
pH_i(time) | 7.20905044774657 |
Q_1(time) | 0.0 |
noble_1962 — v0.0.1Noble, 1962
Details
Parameters:
| Name | Description |
|---|---|
E_L | -60.0 |
g_L | 75.0 |
E_Na | 40.0 |
g_Na_max | 400000.0 |
Cm | 12.0 |
States:
| Name | Description |
|---|---|
V(time) | -87.0 |
h(time) | 0.8 |
m(time) | 0.01 |
n(time) | 0.01 |
noble_2000 — v0.0.1Noble, 2000
Details
Parameters:
| Name | Description |
|---|---|
T | 310.0 |
stim_start | 200.0 |
g_Kr2 | 0.0017 |
P_kna | 0.03 |
alpha_Calmod | 100000.0 |
g_bca | 0.00025 |
alpha_Trop | 100000.0 |
length | 74.0 |
d_NaCa | 0.0 |
K_leak_rate | 0.05 |
alpha_up | 0.4 |
i_NaK_max | 0.7 |
g_to | 0.005 |
delta_f | 0.0001 |
Trop | 0.05 |
Cm | 9.5e-5 |
beta_up | 0.03 |
FRiNaCa | 0.001 |
g_Kr1 | 0.0028 |
FrICa | 0.7 |
K_cyca | 0.0003 |
beta_Trop | 200.0 |
K_mNa | 40.0 |
g_bna | 0.0006 |
g_Ks | 0.0016 |
g_K1 | 0.5 |
delta_m | 1.0e-5 |
P_Ca_L | 1.0 |
KCaChoff | 0.01 |
K_srca | 0.5 |
V_e_ratio | 0.4 |
Na_o | 140.0 |
V_ds_ratio | 0.1 |
stim_duration | 0.002 |
speed_d | 3.0 |
Kdecay | 10.0 |
K_m_rel | 250.0 |
g_tos | 0.0 |
n_NaCa | 3.0 |
Kmdsinact | 0.001 |
Ca_o | 2.0 |
shift_h | 0.0 |
V_up_ratio | 0.01 |
stim_period | 1.0 |
stim_end | 600.0 |
K_mk1 | 10.0 |
K_m_Ca_ds | 0.01 |
Calmod | 0.02 |
radius | 12.0 |
beta_Calmod | 50.0 |
K_o | 4.0 |
K_m_Ca_cyt | 0.0005 |
K_xcs | 0.4 |
V_rel_ratio | 0.1 |
P_CaK | 0.002 |
K_mK | 1.0 |
g_Na | 0.5 |
speed_f | 0.3 |
g_pna | 0.0027 |
stim_amplitude | -6.0 |
P_CaNa | 0.01 |
gamma | 0.2 |
k_NaCa | 0.0005 |
R | 8314.472 |
F | 96485.3415 |
States:
| Name | Description |
|---|---|
d(time) | 0.0 |
Ca_Trop(time) | 0.0003732 |
xr2(time) | 2.0e-7 |
Ca_rel(time) | 0.6460487 |
V(time) | -92.8915042 |
h(time) | 0.9944559 |
xs(time) | 0.0006469 |
f(time) | 0.0 |
K_i(time) | 136.1745362 |
ProdFrac(time) | 0.6950649 |
ActFrac(time) | 0.0049039 |
Ca_ds(time) | 2.7e-6 |
r(time) | 0.0 |
m(time) | 0.0016111 |
xr1(time) | 1.02e-5 |
Ca_i(time) | 1.49e-5 |
s(time) | 0.9948645 |
Ca_up(time) | 0.36963 |
Na_i(time) | 7.6713487 |
Ca_Calmod(time) | 0.0005841 |